Impact of peripheral virus infection on the central nervous system

Infectious Center One Health (ICOH)

New insights into the fusion process of porcine reproductive and respiratory syndrome virus (PRRSV) in macrophages show the way for the development of effective PRRS vaccines

Characterization and functions of haemocytes in honeybees

Detecting the receptor of alphaherpesviruses in mammals

Development of a new intranasal vaccine against respiratory and reproductive problems caused by equine herpesvirus 1

Doctoral project Abubakar Garba

Doctoral project Aludee Jane Andrade

Doctoral project Annelike Dedeurwaerder

Doctoral project Ben Vermeulen

Doctoral project Caroline Bonckaert

Doctoral project Colas Soldan

Doctoral project Delphine Acar

Doctoral project Dominique Olyslaegers

Doctoral project Eline Van Crombrugge

Doctoral project Getnet Adiss

Doctoral project Haileleul Negussie Dubale

Doctoral project Ines Zarak

Doctoral project Inge Decorte

Doctoral project Inge Roukaerts

Doctoral project Ivan Trus

Doctoral project Jiexiong Xie

Doctoral project Jing Zhao

Doctoral project Jolien Van Cleemput

Doctoral project Jun Cao

Doctoral project Jun Xiang

Doctoral project Kasper Meyntjens

Doctoral project Kathlyn Laval

Doctoral project Katrien Poelaert

Doctoral project Kelly Rediger

Doctoral project Khuong Van Thuong

Doctoral project Lennert Steukers

Doctoral project Leslie Bosseler

Doctoral project Liping Huang

Doctoral project Lowiese Desmarets

Doctoral project Mieke Verbeeck

Doctoral project Miet De Baere

Doctoral project Mostafa Rakhshani Nejad

Doctoral project Noémie Tybebo

Doctoral project Quinten Bernaert

Doctoral project Rhea Creve

Doctoral project Robin Haes

Doctoral project Ruifang Wei

Doctoral project Sabrina Vairo

Doctoral project Sarah Descamps

Doctoral project Sebastiaan Theuns

Doctoral project Sebastiaan Van Bockstael

Doctoral project Shunchuan Zhang

Doctoral project Tingting Cui

Doctoral project Toon Rosseel

Doctoral project Uladzimir Karniychuk

Doctoral project Veerle Stroobants

Doctoral project Vishwanatha Reddy Avalakuppa Papi Reddy

Doctoral project Vo Van Tuan

Doctoral project Wendy Baetens

Doctoral project Wenfeng Li

Doctoral project Wim Van Raemdonck

Doctoral project Xiaolei Ren

Doctoral project Xiaoyun Yang

Doctoral project Yewei Li

Early pathogenesis of African swine fever

Effect of viral and host genetics on the PCV2 replication in lymphoblasts and clearance by monocytes

Feline coronavirus-infections in cats in Flanders: epidemiology and pathogenesis.

Feline coronavirus-infections in cats in Flanders: epidemiology and pathogenesis.

Impact of Porcine Hemagglutinating Encephalomyelitis Virus (PHEV) peripheral infection on the swine brain.

In-depth analysis of trans-generational immune priming routes in honeybees in their natural environment (B-immmune)

Molecular pathogenesis of the coronakiller ‘feline infectious peritonitis’ in cats.

Mucus matters: unraveling its role in age -dependent susceptibility to enteric viral infections

NK-like activities of a new population of nonadherent, lymphocyte-like haemocytes in shrimp

Opportunities for genetic selection for resistance to PRRS infection in pigs in Belgium

Opportunities for genetic selection for resistance to PRRS infection in pigs in Belgium

Pathogenesis of coronaviral diseases in humans and animals

Resistance against PRRSV and PCV2 in pigs

Revolutionizing viral and bacterial diagnostics in veterinary medicine using nanopore sequencing

Susceptibility of perivenous macrophages to PRRSV and ASFV and search for PRRSV/ASFV entry mediators by the use of monoclonal antibodies

The Discovery of the shrimp nephrocomplex (revision of the antennal gland) and its role during WSSV-entry and the moulting process

The nasal frontier: decoding the acute stage of PRRSV and ASFV infection, resulting in new insights in porcine nasal macrophages

Unraveling the fusion of porcine reproductive and respiratory syndrome virus in its target cell, the cornerstone for the development of more efficient vaccines

Use of frontline technologies to screen pathogens, environment and pigs for a better disease control in swine herds

VIRUS DISCOVERY IN SMALL MAMMALS: A CLOSER LOOK AT THE FAMILIES ARTERIVIRIDAE AND PARAMYXOVIRIDAE

Characterization of viral-induced proteinopathies in mammals

Doctoral project Sofía González Hernández

Doctoral project Waqar Zaib

Herpesvirus-induced neuroinflammation in the peripheral nervous system (PNS) as a 'distant' trigger of Alzheimer's disease

Identification of alphaherpesvirus mechanisms that suppress the activity of plasmacytoid dendritic cells

Investigating the neuropathogenesis of Herpes Simplex Virus type 1 (HSV-1) in a transgenic Alzheimer's disease mouse model

Karakterisering van microgliale celactivering bij perifere virale infecties

Prevalence, Genetic Variation, and Cross-Species Transmission of small ruminant lentiviruses in Belgium: A study to Enhance Diagnostic Strategies and Support the voluntary control program.

Pseudorabies virus interaction with innate antiviral interferons in porcine epithelial cells

Unravelling the fundamental pathogenesis steps of feline immunodeficiency virus (FIV) to develop a genetic cure for FIV

Advanced vaccines and pharmaceuticals targeted to macrophages via sialoadhesin

Alphaherpesviruses and the innate antiviral defence in the respiratory and genital tract: a fight for supremacy

Aspects of porcine arterivirus entry in macrophages leading to virus persistence

Characteristic glycosylation patterns displayed on porcine reproductive and respiratory syndrome virus (PRRSV) and PRRSV-infected cells and their role in interactions with sialic acid-binding immune system lectins

Characterization of the infection and invasion of alphaherpesviruses in the respiratory and genital mucosae.

Comparative transgenerational immunity in African and European bees.

Control of feline enteric coronavirus in Flemish shelters and catteries to prevent feline infectious peritonitis

Control of highly virulent/pathogenic European porcine reproductive and respiratory syndrome viruses

Creation of a PRRSV-sensitive cell line for use in vaccine production by stable expression of

Credit for the sake of Social and humanitarian RedenenAbubakar Gabrba

Crustacean Cell Cultures: Strengthening IP position and preparation of license track (CruCell)

Decontamination infrastructure for the animal research center on highly infectious human and veterinary pathogens (HIPath)

Developing a diagnostic strategy and optimizing preventive means to recognize and control rotavirus infections in young piglets

Development of an adaptable vector vacinne against Porcine Epidemic Diarrhoea Virus

Development of an anti-immune evasion therapy for the Feline Immunodeficiency Virus

Development of a safe and efficacious intranasal equine herpesvirus-1 (EHV-1) vaccine based on novel insights in the pathogenesis of EHV-1 infections

Development of a sample collection/preparation device for accurate fast diagnostics of viruses and bacteria

Development of a ‘sample-to-diagnostic report’ pipeline for revolutionizing diagnostics of infectious diseases in veterinary medicine.

Development of customizable attenuated and vector vaccines to protect against porcine reproductive and respiratory syndrome (PRRS), essential for a successful treatment

Development of equine herpesvirus 1 vaccine based on new insights into the pathogenesis of foeto- and neuro virulent equine herpesvirus 1 strains

Development of fast assays for the identification of SARS-CoV-2-infected/immune humans/animals and potential human-animal-human transmissions

Early replication stages of feline enteric coronavirus in its real target cell, the enterocyte.

Entry of feline coronaviruses in their primary target cells

Entry process of porcine arterivirus in macrophages and link with virulence/pathogenicity 

Entry process of porcine arterivirus in macrophages and link with virulence/pathogenicity

Entry process of porcine arterivirus in macrophages and link with virulence/pathogenicity

Equipement for a new L3 laboratory enabling in vitro experiments with high risk pathogens

Evaluation of the protective effect and the mode of action of fatty acids based products against shrimp pathogens

Exploration of macrophage-specific molecules for cell-directed therapy

FIP-project: Feline infectious peritonitis

Functions of a new subpopulation of non-adherent, lymphocyte-like haemocytes in shrimp

Genetic Characterization and molecular epidemiology of equine herpes virus 1 in working equids in Ethiopia

Host factors that determine the clinical outcome (subclinical versus peralysis) during an infection with neurovirulent equine herpesvirus type 1 in horses

Immune evasion of eqiune herpesvirus type 1

Immune evasion of the feline infectious peritonitis virus kattenmonocyten.

Immune responses of swine to highly virulent Chinese porcine reproductive and respiratory syndrome virus (PRRSV)

Immune responses of swine to highly virulent Chinese porcine reproductive and respiratory syndrome virus (PRRSV)

Impact of stromal cells of different lymphoid tissues on the replication of feline immunodeficiency virus in monocytic cells and T-lymphocytes

Improving livelihood through control of viral diseases affecting short cycle stocks

Invasion of alphaherpesviruses through the genital mucosa: elucidation of the mechanism with a view to improving the prevention and treatment

Molecular analysis of the cytoplasmic tail of sialoadhesin, the driving force behind this multifunctional receptor. As well as analysis of the pathways that are altered upon ligand-induced sialoadhesin endocytosis, and the effect on antigen presentation

New intranasal marker vector vaccine for protection of horses against equine herpesvirus 1 related and other (re)emerging viral diseases.

New intranasal marker vector vaccine for protection of horses against equine herpesvirus 1 related and other (re)emerging viral diseases.

Pathogenesis of viral diseases in animals

Pathogenetic processes for viral diseases of mammals

PEDetect: Validation of diagnostic tests for the detection and monitoring of porcine epidemic diarrhoea virus in Belgium

Pig MinION

Possibilities of oral vaccination of pigs against Aujeszky's disease

Production of immunotolerant pigs to PCV1 and PCV2 and approach to reproduce postweaning multisystemic wasting syndrome (PMWS)

Receptor identification for porcine viruses with a macrophage tropism (African swine fever virus (ASFV), porcine reproductive and respiratory syndrome virus (PRRSV))

Replacement of confocal fluorescence microscope for visualisation of biological processes in humans and animals

Research into new methods for the prevention and control of PRRS in pigs

Role of accessory proteins in the evolution of the Feline Enteric Coronavirus to the Feline Infectious Peritonitis Virus, prospects for a new diagnosis

Role of monocytic cells in the pathogenesis of nephropathogenic infectious bronchitis virus (IBV) in chickens

Role of non-phagocytic, lymphocyte-like haemocytes in the antiviral and antibacterial defence of shrimp

Role of viral glycans and siglec receptors for infection of macrophages and viral immune evasion

Safe universal vector vaccine for oral vaccination in swine

Shrimp defense against White Spot Syndrome Virus

Strengthening Animal Production and Health through the Immune Response

Study of the cellular protease activity in the replication cycle of the porcine reproductive and respiratory syndrome virus for the targeted development of vaccines and vaccine virus production

Study of the pathogenesis (role of host receptors) of African Swine Fever (ASF) and innate immune response in ASF virus infected domestic pigs

The development of a treatment for feline infectious peritonitis virus (FIPV)

Transplacental PRRSV transmission and pathogenesis of PRRSV- induced abortions is sows

Ultracentrifuge for virological and cell biological applications.

Unraveling the honeybee colony mortality complex using an intensive long-term study with revolutionary diagnostic tools and exposure experiments

Unraveling the role of porcine rotaviruses in the pathogenesis of piglet diarrhea and assessment of their potential for interspecies transmission

Upregulation of sialyl lewis X of Feline Infectious Peritonitis, a basis for the development of a diagnostic test

Urokinase plasminogen activator-inhibitors, new drugs for treatment of herpesvirusassociated

Use of frontline technologies to screen pathogens, environment and pigs for a better disease control in swine herds

Use of uPA inhibitors to block invasion of alphaherpesviruses through the mucosa (type 3)

Using the myosin light chain kinase as a target for screening candidate anti-virals

VeRONICa: Validation of Research On Nano-electronic Integrated Circuits

Viral and cellular factors that determine virus replication and clinical picture during infections with equine arteritisvirus in horse

Virus host interplay at the early stages of infection

Virus infections of man and animal

Development of an innovative range of antiseptics / disinfectants

Evaluation of the protective effect and the mode of action of fatty acids based products against shrimp pathogens

Live cell analysis equipment for the study of biosafety level BSL3 pathogens

Robust state-of-the-art 3-laser flow cytometer

Robust, user-friendly and state-of-the-art fluorescence activated cell sorter (FACS)

The development of an anti-immune evasion therapy for FIV

Strategic Institutional Partnership Can Tho University 2020-2022