Research Explorer

Project

Characteristic glycosylation patterns displayed on porcine reproductive and respiratory syndrome virus (PRRSV) and PRRSV-infected cells and their role in interactions with sialic acid-binding immune system lectins
Code
01P09311
Duration
01 October 2011 → 30 September 2014
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Microbiology
Keywords
immune system lectins PRRSV glycosylation
 
Project description
 

Porcine reproductive and respiratory syndrome virus (PRRSV) is an important pathogen of swine. This research project aims to analyze the nature of the virus-linked glycans and the influence of PRRSV infection on cellular glycosylation. Furthermore, the interaction of these glycans with sialic acid-binding immune system lectins will be analyzed, as these are often crucial in regulation of immune responses.