Research Explorer

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Researcher

Hans Nauwynck

Awards & Distinctions

750 Results

2023

Effect of salinity drop on susceptibility to WSSV infection in Litopenaeus vannamei shrimp using a per os challenge model

Natasja CoxEvelien De SwaefMathias CorteelWim Van Den BroeckPeter BossierJoão José Pereira Dantas Da Rocha LimaHans Nauwynck

Effect of viral and host genetics on pcv2 replication in lymphoblasts and clearance by monocytes

Yueling OuyangHans Nauwynck

Genotyping and phylogeography of Infectious Bronchitis Virus isolates from Pakistan show unique linkage to GI-24 lineage

Waqar SaleemNick VereeckeMuhammad Goher ZamanFarhan AfzalIqra RemanSaeed ul-Hasan KhanHans Nauwynck

A1 Journal Article in POULTRY SCIENCE

Predictive power of long-read whole-genome sequencing for rapid diagnostics of multidrug-resistant brachyspira hyodysenteriae strains

Nick VereeckeNadine BotteldoornCharlotte BrosséCaroline BonckaertHans NauwynckFreddy HaesebrouckFilip BoyenDominiek MaesSebastiaan Theuns

A1 Journal Article in MICROBIOLOGY SPECTRUM

Prevalence, genetic variation, and cross-species transmission of small ruminant lentiviruses in Belgium : a study to enhance diagnostic strategies and support the voluntary control program

Rodolphe MichielsNick De ReggeHans Nauwynck

Revolutionizing viral and bacterial diagnostics in veterinary medicine using nanopore sequencing

Nick VereeckeHans NauwynckSebastiaan TheunsFreddy HaesebrouckMarjan De Mey

Selection and validation of reference genes for RT-qPCR normalization of porcine alveolar macrophages (PAMs) for PRRSV studies

Dayoung OhWard De SpiegelaereHans Nauwynck

A1 Journal Article in SCIENTIFIC REPORTS

Several Alphaherpesviruses interact similarly with the NF-κB pathway and suppress NF-κB-dependent gene expression

Nicolás Romero RataAlexander Tishchenko KhoruzhRuth VerhammeShelly M. M. Wuerzberger-DavisCliff Van WaesbergheHans NauwynckShigeki MiyamotoHerman Favoreel

A1 Journal Article in MICROBIOLOGY SPECTRUM

Successful whole genome nanopore sequencing of swine influenza a virus (swIAV) directly from oral fluids collected in Polish pig herds

Nick VereeckeAleksandra WoźniakMarthe PauwelsSieglinde CoppensHans NauwynckPiotr CybulskiSebastiaan TheunsTomasz Stadejek

A1 Journal Article in VIRUSES-BASEL

Susceptibility of perivenous macrophages to PRRSV-1 subtype 1 LV and PRRSV-1 subtype 3 Lena using a new vein explant model

Shaojie HanDayoung OhJiexiong XieHans Nauwynck

A1 Journal Article in FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

The nasal frontier : decoding the acute stage of PRRSV and ASFV infection resulting in new insights in porcine nasal macrophages

Dayoung OhHans Nauwynck

The way of water : unravelling White Spot Syndrome Virus (WSSV) transmission dynamics in Litopenaeus vannamei shrimp

Natasja CoxEvelien De SwaefMathias CorteelWim Van Den BroeckPeter BossierJoão José Pereira Dantas Da Rocha LimaHans Nauwynck

A1 Journal Article in VIRUSES-BASEL

2022

A new long noncoding RNA, MAHAT, inhibits replication of porcine reproductive and respiratory syndrome virus by recruiting DDX6 to bind to ZNF34 and promote an innate immune response

Yuming LiuXing LiuJuan BaiYangyang SunHans NauwynckXianwei WangYuanqi YangPing Jiang

A1 Journal Article in JOURNAL OF VIROLOGY

Addressing personal protective equipment (PPE) decontamination : methylene blue and light inactivates severe acute respiratory coronavirus virus 2 (SARS-CoV-2) on N95 respirators and medical masks with maintenance of integrity and fit

Thomas Sean LendvayJames ChenBrian H. HarcourtFlorine E. M. ScholteYing Ling LinF. Selcen Kilinc-BalciMolly M. LambKamonthip HomdayjanakulYi CuiAmy Price et al.

A1 Journal Article in INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Age-dependent invasion of pseudorabies virus into porcine central nervous system via maxillary nerve

Konstantinos PapageorgiouIoannis GrivasMaria ChiotelliAlexandros TheodoridisEmmanuel PanterisDimitris PapadopoulosEvanthia PetridouNikolaos PapaioannouHans NauwynckSpyridon K. Kritas

A1 Journal Article in PATHOGENS

Bacterial toxins from Staphylococcus aureus and Bordetella bronchiseptica predispose the horse’s respiratory tract to equine herpesvirus type 1 infection

Eline Van CrombruggeEmma VanbeylenJolien Van CleemputWim Van Den BroeckKathlyn LavalHans Nauwynck

A1 Journal Article in VIRUSES-BASEL

Cluster of differentiation frequency on antigen presenting-cells : the next step to cervical cancer prognosis?

Parisa Shiri AghbashMilad ShirvalilooAmmar Khalo Abass KashoFarbod AlinezhadHans NauwynckHossein Bannazadeh Baghi

A1 Journal Article in INTERNATIONAL IMMUNOPHARMACOLOGY

Development of standardized in vivo white spot syndrome virus (WSSV) individual and group challenge models for experimental infection studies in Litopenaeus vannamei shrimp

Natasja CoxEvelien De SwaefMathias CorteelWim Van Den BroeckPeter BossierJoão José Pereira Dantas Da Rocha LimaHans Nauwynck

Functional analysis of human and feline coronavirus cross-reactive antibodies directed against the SARS-CoV-2 fusion peptide

Nathalie VanderheijdenAnnelies StevaertJiexiong XieXiaolei RenCyril BarbezangeSam NoppenIsabelle DesombereBruno VerhasseltPeter GeldhofNick Vereecke et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Genomics-based epidemiology and antimicrobial susceptibility of Mycoplasma bovis isolates from veal, dairy, and beef herds

Jade BokmaNick VereeckeLinde GilleLaura Van DriesscheKoen De BleeckerHans NauwynckFreddy HaesebrouckSebastiaan TheunsFilip BoyenBart Pardon

Hemocyten van de honingbij (Apis mellifera), een babylonische spraakverwarring

Cato Van HerzeleHans NauwynckDirk de Graaf

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Innate antiviral responses in porcine nasal mucosal explants inoculated with influenza A virus are comparable with responses in respiratory tissues after viral infection

Sofie M. R. StarbaekMalene Rask AndersenLouse BrogaardAnna SpinelliVictoria RapsonHelena Aagaard GludLars E. LarsenPeter M. H. HeegaardHans NauwynckKerstin Skovgaard

A1 Journal Article in IMMUNOBIOLOGY

Milk lactose protects against porcine group A rotavirus infection

Xiaolei RenWaqar SaleemRobin HaesJiexiong XieSebastiaan TheunsHans Nauwynck

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Molecular epidemiology of Porcine Parvovirus Type 1 (PPV1) and the reactivity of vaccine-induced antisera against historical and current PPV1 strains

Nick VereeckeLise Kirstine KvisgaardGuy BaeleCarine BooneMarius KunzeLars Erik LarsenSebastiaan TheunsHans Nauwynck

A1 Journal Article in VIRUS EVOLUTION

Nanopore sequencing as a rapid diagnostic tool for identification, strain typing, and antimicrobial susceptibility testing of Mycoplasma bovis

Jade BokmaNick VereeckeFreddy HaesebrouckHans NauwynckSebastiaan TheunsFilip BoyenBart Pardon

Virus discovery in small mammals : a closer look at the families arteriviridae and paramyxoviridae

Bert VanmechelenHans NauwynckPiet MaesSebastiaan Theuns

2021

'Don, doff, discard' to 'don, doff, decontaminate'-FFR and mask integrity and inactivation of a SARS-CoV-2 surrogate and a norovirus following multiple vaporised hydrogen peroxide-, ultraviolet germicidal irradiation-, and dry heat decontaminations

Louisa F. Ludwig-BegallConstance WielickOlivier JoloisLorene DamsRavo M. RazafimahefaHans NauwynckPierre-Francois DemeuldreAurore NappJan LaperreEtienne Thiry et al.

A1 Journal Article in PLOS ONE

A substantial neutrophilic inflammation as regular part of severe type 2 chronic rhinosinusitis with nasal polyps

Tim DelemarreGabriële HoltappelsNatalie De RuyckNan ZhangHans NauwynckClaus BachertElien Gevaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

African swine fever virus circulation between Tanzania and neighboring countries : a systematic review and meta-analysis

Jean N. HakizimanaClara YonaOlivier KamanaHans NauwynckGerald Misinzo

A1 Journal Article in VIRUSES-BASEL

Comparison of primary virus isolation in pulmonary alveolar macrophages and four different continuous cell lines for type 1 and type 2 porcine reproductive and respiratory syndrome virus

Jiexiong XieNick VereeckeSebastiaan TheunsDayoung OhNathalie VanderheijdenIvan TrusJannes SauerPhilip VytCaroline BonckaertChristian Lalonde et al.

A1 Journal Article in VACCINES

Complete genome analysis of African swine fever virus responsible for outbreaks in domestic pigs in 2018 in Burundi and 2019 in Malawi

Jean N. HakizimanaJean B. NtirandekuraClara YonaLionel NyabongoGladson KamwendoJulius L. C. ChuluDesire NtakirutimanaOlivier KamanaHans NauwynckGerald Misinzo

A1 Journal Article in TROPICAL ANIMAL HEALTH AND PRODUCTION

Environmental stability of porcine respiratory coronavirus in aquatic environments

Maarten De RijckeMohammed Hisham ShaikhJan MeesHans NauwynckMichiel Bert Vandegehuchte

A1 Journal Article in PLOS ONE

Evaluation of nanopore sequencing as a diagnostic tool for the rapid identification of Mycoplasma bovis from individual and pooled respiratory tract samples

Jade BokmaNick VereeckeMathilde PasLaurens ChantillonMarianne VahlEefke WeesendorpRuud H. DeurenbergHans NauwynckFreddy HaesebrouckSebastiaan Theuns et al.

A1 Journal Article in JOURNAL OF CLINICAL MICROBIOLOGY

Genome sequences of equine herpesvirus 1 strains from a European outbreak of neurological disorders linked to a horse gathering in Valencia, Spain, in 2021

Nick VereeckeFlora CarnetStéphane PronostKatleen VanschandevijlSebastiaan TheunsHans Nauwynck

A2 Journal Article in MICROBIOLOGY RESOURCE ANNOUNCEMENTS

Genome-wide association study reveals genetic markers for antimicrobial resistance in Mycoplasma bovis

Jade BokmaNick VereeckeHans NauwynckFreddy HaesebrouckSebastiaan TheunsBart PardonFilip Boyen

A1 Journal Article in MICROBIOLOGY SPECTRUM

Glyceraldehyde-3-phosphate dehydrogenase restricted in cytoplasmic location by viral GP5 facilitates porcine reproductive and respiratory syndrome virus replication via its glycolytic activity

Xuewei LiuXing LiuJuan BaiYanni GaoZhongbao SongHans NauwynckXianwei WangYuanqi YangPing Jiang

A1 Journal Article in JOURNAL OF VIROLOGY

ICTV virus taxonomy profile : Arteriviridae 2021

Margo A. BrintonAnastasia A. GulyaevaUdeni B. R. BalasuriyaMagda DunowskaKay S. FaabergTony GoldbergFrederick C. C. LeungHans NauwynckEric J. SnijderTomasz Stadejek et al.

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Mycoplasma bovis point mutations as genetic markers for antimicrobial resistance revealed by Genome Wide Association Study (lecture, 12 min.)

Nick VereeckeJade BokmaFreddy HaesebrouckHans NauwynckSebastiaan TheunsBart PardonFilip Boyen

Organ-specific genome diversity of replication-competent SARS-CoV-2

Jolien Van CleemputWillem van SnippenbergLaurens LambrechtsAmélie DendoovenValentino D'OnofrioLiesbeth CouckWim TrypsteenJan VanrusseltSebastiaan TheunsNick Vereecke et al.

A1 Journal Article in NATURE COMMUNICATIONS

Presence of broad-spectrum beta-lactamase-producing Enterobacteriaceae in zoo mammals

Chloë De WitteNick VereeckeSebastiaan TheunsClaudia De RuyckFrancis VercammenTim BoutsFilip BoyenHans NauwynckFreddy Haesebrouck

A1 Journal Article in MICROORGANISMS

Semi-quantitative risk assessment by expert elicitation of potential introduction routes of African swine fever from wild reservoir to domestic pig industry and subsequent spread during the Belgian outbreak (2018-2019)

Axel MauroyPieter DepoorterClaude SaegermanBrigitte CayNick De ReggeMaria-Eleni FilippitziClaude FischerMartine LaitatDominiek MaesKevin Morelle et al.

A1 Journal Article in TRANSBOUNDARY AND EMERGING DISEASES

The discovery of the shrimp nephrocomplex (revision of the antennal gland) and its role during WSSV-entry and the moulting process

Gaëtan De GryseHans NauwynckPeter Bossier

The pathogenesis and immune evasive mechanisms of equine herpesvirus type 1

Kathlyn LavalKatrien C. K. PoelaertJolien Van CleemputJing ZhaoAnnelies P. VandekerckhoveAnnick C. GryspeerdtBarbara GarréKaren van der MeulenHossein B. BaghiHaileleul N. Dubale et al.

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

2020

A comparative study of techniques used for the diagnosis of effusive feline infectious peritonitis

Arnaut HellemansDelphine AcarVeerle StroobantsSebastiaan TheunsL. M. B. DesmaretsHans Nauwynck

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

An alphaherpesvirus exploits antimicrobial beta-defensins to initiate respiratory tract infection

Jolien Van CleemputKatrien PoelaertKathlyn LavalNathalie VanderheijdenMaarten DhaenensSimon DaledFilip BoyenFrank PasmansHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

Characterization of feline herpesvirus-1 deletion mutants in tissue explant cultures

Yao LeeRoger MaesMatti KiupelHans NauwynckGisela Soboll Hussey

A1 Journal Article in VIRUS RESEARCH

Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis

Elien GevaertTim DelemarreJoyceline De VolderNan ZhangGabriële HoltappelsNatalie De RuyckEmma PerssonInes HeyndrickxKenneth VerstraeteHelena Catharine Aegerter et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genetic analysis of African swine fever virus from the 2018 outbreak in South-Eastern Burundi

Jean N. HakizimanaLionel NyabongoJean B. NtirandekuraClara YonaDésiré NtakirutimanaOlivier KamanaHans NauwynckGerald Misinzo

A1 Journal Article in FRONTIERS IN VETERINARY SCIENCE

Genetic profile of African swine fever virus responsible for the 2019 outbreak in northern Malawi

J. N. HakizimanaG. KamwendoJ. L. C. ChuluO. KamanaHans NauwynckG. Misinzo

A1 Journal Article in BMC VETERINARY RESEARCH

High quality MinION and Flongle long-read nanopore genome assemblies of Mycoplasma bovis using taxon-specific training of the Bonito basecaller

Nick VereeckeJade BokmaBart PardonFilip BoyenHans NauwynckSebastiaan Theuns

High quality genome assemblies of Mycoplasma bovis using a taxon-specific Bonito basecaller for MinION and Flongle long-read nanopore sequencing

Nick VereeckeJade BokmaFreddy HaesebrouckHans NauwynckFilip BoyenBart PardonSebastiaan Theuns

A1 Journal Article in BMC BIOINFORMATICS

Isolation and characterization of a new population of nasal surface macrophages and their susceptibility to PRRSV-1 subtype 1 (LV) and subtype 3 (Lena).

Dayoung OhJiexiong XieNathalie VanderheijdenHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

New insights about vaccine effectiveness : Impact of attenuated PRRS-strain vaccination on heterologous strain transmission

Margo Chase-ToppingJiexiong XieChristopher PooleyIvan TrusCaroline BonckaertKelly RedigerRichard I. BaileyHelen BrownVasiliki BitsouniMaria Belén Barrio et al.

A1 Journal Article in VACCINE

Persistent domestic circulation of African swine fever virus in Tanzania, 2015–2017

Clara M. YonaMerijn VanheeEdgar SimulunduMariam MakangeHans NauwynckGerald Misinzo

A1 Journal Article in BMC VETERINARY RESEARCH

Phylogenomic analysis and antimicrobial susceptibility data of Mycoplasma bovis from different Belgian cattle production systems

Jade BokmaNick VereeckeKoen De BleeckerJozefien CallensHans NauwynckFreddy HaesebrouckSebastiaan TheunsBart PardonFilip Boyen

Phylogenomic analysis of Mycoplasma bovis from Belgian veal, dairy and beef herds

Jade BokmaNick VereeckeKoen De BleeckerJozefien CallensStefaan RibbensHans NauwynckFreddy HaesebrouckSebastiaan TheunsFilip BoyenBart Pardon

A1 Journal Article in VETERINARY RESEARCH

Porcine reproductive and respiratory syndrome virus Nsp4 cleaves ZAP to antagonize its antiviral activity

Yongxiang ZhaoZhongbao SongJuan BaiXuewei LiuHans NauwynckPing Jiang

A1 Journal Article in VETERINARY MICROBIOLOGY

Role of Porcine Aminopeptidase N and Sialic Acids in Porcine Coronavirus Infections in Primary Porcine Enterocytes.

Tingting CuiSebastiaan TheunsJiexiong XieWim Van Den BroeckHans Nauwynck

A1 Journal Article in Viruses

Role of porcine amino peptidase N and sialic acids in porcine coronavirus infections in primary porcine enterocytes

Tingting CuiSebastiaan TheunsJiexiong XieWim Van Den BroeckHans Nauwynck

A2 Journal Article in VIRUSES

The attenuated pseudorabies virus vaccine strain Bartha K61 : a brief review on the knowledge gathered during 60 years of research

Jonas DelvaHans NauwynckThomas C. MettenleiterHerman Favoreel

A1 Journal Article in PATHOGENS

The involvement of viral and cellular proteins in the enigmatic feline coronavirus pathogenesis : a molecular and cell biology approach

Delphine AcarHans NauwynckXavier Saelens

The shrimp nephrocomplex serves as a major portal of pathogen entry and is involved in the molting process

Gaëtan De GryseKhuong Van ThuongBenedicte DescampsWim Van Den BroeckChristian VanhovePieter CornilliePatrick SorgeloosPeter BossierHans Nauwynck

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The use of germicidal ultraviolet light, vaporized hydrogen peroxide and dry heat to decontaminate face masks and filtering respirators contaminated with a SARS-CoV-2 surrogate virus

L. F. Ludwig-BegallC. WielickL. DamsHans NauwynckP-F DemeuldreA. NappJ. LaperreE. HaubrugeE. Thiry

A1 Journal Article in JOURNAL OF HOSPITAL INFECTION

Type 2 inflammation in chronic rhinosinusitis without nasal polyps : another relevant endotype

Tim DelemarreGabriële HoltappelsNatalie De RuyckNan ZhangHans NauwynckClaus BachertElien Gevaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

2019

25-Hydroxycholesterol provides antiviral protection against highly pathogenic porcine reproductive and respiratory syndrome virus in swine

Zhongbao SongJuan BaiHans NauwynckLv LinXuewei LiuJie YuPing Jiang

A1 Journal Article in VETERINARY MICROBIOLOGY

A DNA prime immuno-potentiates a modified live vaccine against the porcine reproductive and respiratory syndrome virus but does not improve heterologous protection

Cindy Bernelin-CottetCeline UrienMaxence FretaudChristelle LangevinIvan TrusLuc JouneauFany BlancJean-Jacques LeplatCeline BarcOlivier Boulesteix et al.

A1 Journal Article in VIRUSES-BASEL

A DNA-modified live vaccine prime-boost strategy broadens the T-cell response and enhances the antibody response against the porcine reproductive and respiratory syndrome virus

Cindy Bernelin-CottetCeline UrienElisabeth StubsrudVirginie JakobEdwige BouguyonElise BordetCeline BarcOlivier BoulesteixVanessa ContrerasChristophe Barnier-Quer et al.

A1 Journal Article in VIRUSES-BASEL

A new co-culture system of primary porcine enterocytes/myofibroblasts to investigate the replication characteristics of porcine enteric viruses in their target cell

Tingting CuiHans NauwynckSebastiaan Theuns

A triple amino acid substitution at position 88/94/95 in glycoprotein GP2a of type 1 porcine reproductive and respiratory syndrome virus (PRRSV1) is responsible for adaptation to MARC-145 cells

Jiexiong XieIvan TrusDayoung OhLise K KvisgaardJulie CF RappeNicolas RuggliNathalie VanderheijdenLars E LarsenFrançois LefèvreHans Nauwynck

A1 Journal Article in VIRUSES

Better insights in porcine circovirus type 2 (PCV2) epidemiology and cellular pathogenesis

Ruifang WeiHans Nauwynck

Beyond gut instinct : metabolic short-chain fatty acids moderate the pathogenesis of alphaherpesviruses

Katrien PoelaertJolien Van CleemputKathlyn LavalSarah DescampsHerman FavoreelHans Nauwynck

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Changes on the viral capsid surface during the evolution of porcine circovirus type 2 (PCV2) from 2009 till 2018 may lead to a better receptor binding

Ruifang WeiJiexiong XieSebastiaan TheunsHans Nauwynck

A1 Journal Article in VIRUS EVOLUTION

Demonstration of the efficacy and safety of PRRSV vaccines developed by a new attenuation technology

Caroline BonckaertHans Nauwynck

Deoxynivalenol, but not fumonisin B1, aflatoxin B1 or diesel exhaust particles disrupt integrity of the horse's respiratory epithelium and predispose it for equine herpesvirus type 1 infection

Jolien Van CleemputKatrien PoelaertKathlyn LavalWim Van Den BroeckHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Equine herpesvirus 1 bridles T lymphocytes to reach its target organs

Katrien PoelaertJolien Van CleemputKathlyn LavalHerman FavoreelLiesbeth CouckWim Van Den BroeckWalid AzabHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

Equine herpesvirus 1 infection orchestrates the expression of chemokines in equine respiratory epithelial cells

Katrien PoelaertJolien Van CleemputKathlyn LavalJiexiong XieHerman FavoreelHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Failure to remove bluetongue serotype 8 virus (BTV-8) from in vitro produced and in vivo derived bovine embryos and subsequent transmission of BTV-8 to recipient cows after embryo transfer

Andy HaegemanLeen VandaeleIlse De LeeuwAndre OliveiraHans NauwynckAnn Van SoomKris De Clercq

A1 Journal Article in FRONTIERS IN VETERINARY SCIENCE

Gammaherpesvirus BoHV-4 infects bovine respiratory epithelial cells mainly at the basolateral side

Bo YangJiexiong XieJolien Van CleemputRuifang WeiGeert OpsomerHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Identification of peptide domains involved in the subcellular localization of the feline coronavirus 3b protein

Delphine AcarVeerle StroobantsHerman FavoreelXavier SaelensHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Immune-metabolic factors mediate the pathogenesis of equine herpesvirus 1 : an evolutionary pas-de-deux

Katrien PoelaertHans NauwynckHerman Favoreel

Interplay between porcine reproductive and respiratory syndrome virus (PRRSV) and cellular entry mediators

Jiexiong XieHans Nauwynck

No evidence for a role for antibodies during vaccination-induced enhancement of porcine reproductive and respiratory syndrome

Carmen A SautterIvan TrusHans NauwynckArtur Summerfield

A1 Journal Article in VIRUSES-BASEL

Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection

Jolien Van CleemputKatrien PoelaertKathlyn LavalFrancis ImpensWim Van Den BroeckKris GevaertHans Nauwynck

A1 Journal Article in SCIENTIFIC REPORTS

Porcine rotavirus mainly infects primary porcine enterocytes at the basolateral surface

Tingting CuiSebastiaan TheunsJiexiong XieHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Presence of gammaherpesvirus BoHV-4 in endometrial cytology samples is not associated with subclinical endometritis diagnosed at artificial insemination in dairy cows

Bo YangOsvaldo Américo Bogado PascottiniJiexiong XieLowiese DesmaretsTingting CuiGeert OpsomerHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Prevalentiestudie naar feliene immunodefiëntievirus en feliene leukosevirus bij straatkatten in Gent

Roy Theodorus Lambertus van VugtHans NauwynckIngeborgh PolisHilde De Rooster

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Replication characteristics of BoHV-4 in respiratory and genital mucosae and lack of association with subclinical endometritis

Bo YangHans NauwynckGeert Opsomer

S100A9 regulates porcine reproductive and respiratory syndrome virus replication by interacting with the viral nucleocapsid protein

Zhongbao SongJuan BaiXuewei LiuHans NauwynckJiaqiang WuXing LiuPing Jiang

A1 Journal Article in VETERINARY MICROBIOLOGY

Strain-dependent porcine circovirus type 2 (PCV2) entry and replication in T-lymphoblasts

Ruifang WeiNicolaas Van RenneHans Nauwynck

A1 Journal Article in VIRUSES-BASEL

Therapeutic effect of Xanthohumol against highly pathogenic porcine reproductive and respiratory syndrome viruses

Xuewei LiuJuan BaiChenlong JiangZhongbao SongYongxiang ZhaoHans NauwynckPing Jiang

A1 Journal Article in VETERINARY MICROBIOLOGY

Toll-like receptor agonists as adjuvants for inactivated porcine reproductive and respiratory syndrome virus (PRRSV) vaccine

Sandra VremanJoanne McCaffreyDitta J Popma-de GraafHans NauwynckHuub FJ SavelkoulAnne MooreJohanna MJ RebelNorbert Stockhofe-Zurwieden

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Unravelling the first key steps in equine herpesvirus type 5 (EHV5) pathogenesis using ex vivo and in vitro equine models

Jolien Van CleemputKatrien PoelaertKathlyn LavalHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Xanthohumol inhibits PRRSV proliferation and alleviates oxidative stress induced by PRRSV via the Nrf2-HMOX1 axis

Xuewei LiuZhongbao SongJuan BaiHans NauwynckYongxiang ZhaoPing Jiang

A1 Journal Article in VETERINARY RESEARCH

ZAP, a CCCH-type zinc finger protein, inhibits porcine reproductive and respiratory syndrome virus replication and interacts with viral Nsp9

Yongxiang ZhaoZhongbao SongJuan BaiXuewei LiuHans NauwynckPing Jiang

A1 Journal Article in JOURNAL OF VIROLOGY

2018

Abortigenic but not neurotropic equine herpes virus 1 modulates the interferon antiviral defense

Katrien PoelaertJolien Van CleemputKathlyn LavalHerman FavoreelGisela Soboll HusseyRoger K MaesHans Nauwynck

A1 Journal Article in FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

Breed differences in PCV2 uptake and disintegration in porcine monocytes

Ruifang WeiIvan TrusBo YangLiping HuangHans Nauwynck

A1 Journal Article in VIRUSES-BASEL

Dissecting clinical outcome of porcine circovirus type 2 with in vivo derived transcriptomic signatures of host tissue responses

Nicolaas Van RenneRuifang WeiNathalie PochetHans Nauwynck

A1 Journal Article in BMC GENOMICS

Establishment of porcine enterocyte/myofibroblast co-cultures for the growth of porcine rota- and coronaviruses

Tingting CuiSebastiaan TheunsLowiese DesmaretsJiexiong XieGaëtan De GryseBo YangWim Van Den BroeckHans Nauwynck

A1 Journal Article in SCIENTIFIC REPORTS

Increased differentiation and PRRSV susceptibility of monocytic cells during co-cultivation with immortalized mesenchymal stromal cells

Abubakar GarbaHans Nauwynck

Introduction to Virology special issue featuring nidovirus research

Ying FangSusan BakerEric SnijderThomas GallagherShinji MakinoHans Nauwynck

Editorial material

Nanopore sequencing as a revolutionary diagnostic tool for porcine viral enteric disease complexes identifies porcine kobuvirus as an important enteric virus

Sebastiaan TheunsBert VanmechelenQuinten BernaertWard DeboutteMarilou VandenholeLeen BellerJelle MatthijnssensPiet MaesHans Nauwynck

A1 Journal Article in SCIENTIFIC REPORTS

Preferential use of Siglec-1 or Siglec-10 by type 1 and type 2 PRRSV strains to infect PK15S1-CD163 and PK15S10-CD163 cells

Jiexiong XieIsaura ChristiaensBo YangIvan TrusBert DevriendtTingting CuiRuifang WeiHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

The horse's respiratory mucosa, airborne pathogens and respirable hazards : the archetypical trifecta of co-evolution

Jolien Van CleemputHans Nauwynck

2017

Access to a main alphaherpesvirus receptor, located basolaterally in the respiratory epithelium, is masked by intercellular junctions

Jolien Van CleemputKatrien PoelaertKathlyn LavalRoger MaesGisela S HusseyWim Van Den BroeckHans Nauwynck

A1 Journal Article in SCIENTIFIC REPORTS

CCL2 and CCL5 driven attraction of CD172a+ monocytic cells during an equine herpesvirus type 1 (EHV-1) infection in equine nasal mucosa and the impact of two migration inhibitors, rosiglitazone (RSG) and quinacrine (QC)

Jing ZhaoKatrien PoelaertJolien Van CleemputHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Contemporary outbreaks of different avipoxviruses in Humboldt penguins of wild animal park Planckendael and in chickens of commercial poultry farms in Belgium

Vishwanatha Reddy Avalakuppa Papi ReddyFrancis VercammenIvan TrusHans Nauwynck

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Detection of equine herpesvirus (EHV) -1, -2, -4 and -5 in Ethiopian equids with and without respiratory problems and genetic characterization of EHV-2 and EHV-5 strains

Haileleul Negussie DubaleD GizawL TesfawYewei LiK OgumaH SentsuiTS TessemaHans Nauwynck

A1 Journal Article in TRANSBOUNDARY AND EMERGING DISEASES

Epidemiology of equine herpesviruses (EHVs) in Ethiopian equids and invasion characteristics of EHV-1 and EHV-3 in respiratory and genital mucosae

Haileleul Negussie DubaleHans NauwynckTesfaye Sisay Tessema

Equine herpesvirus-1 myeloencephalopathy, an emerging threat of working equids in Ethiopia

Haileleul Negussie DubaleDaniel GizawTesfaye TessemaHans Nauwynck

A1 Journal Article in TRANSBOUNDARY AND EMERGING DISEASES

Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in patients with severe airway inflammation

Elien GevaertNan ZhangOlga KryskoFeng LanGabriële HoltappelsNatalie De RuyckHans NauwynckShida YousefiHans-Uwe SimonClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genetic and pathogenic characterization of a Russian subtype 2 PRRSV-1 isolate

Anton G YuzhakovSergei A RaevAndrei N SkrylevAlexander M MishinTatiana V GrebennikovaOleg A VerkhovskyAlexei D ZaberezhnyIvan TrusHans NauwynckTaras I Aliper

A1 Journal Article in VETERINARY MICROBIOLOGY

Genotyping of local feline immunodeficiency virus (FIV) isolates and characterization of FIV replication in peripheral blood mononuclear cells

Inge RoukaertsHans Nauwynck

Hampered cumulus expansion of porcine cumulus-oocyte complexes by excessive presence of alpha2-macroglobulin is likely mediated via inhibition of zinc-dependent metalloproteases

Ruth AppeltantJosine BeekDominiek MaesJo BijttebierKatleen Van SteendamHans NauwynckAnn Van Soom

A1 Journal Article in ANIMAL SCIENCE JOURNAL

Identification of an enterovirus recombinant with a torovirus-like gene insertion during a diarrhea outbreak in fattening pigs

Nádia Conceição-NetoSebastiaan TheunsTingting CuiMark ZellerClaude Kwe YindaIsaura ChristiaensElisabeth HeylenMarc Van RanstSebastien CarpentierHans Nauwynck et al.

A1 Journal Article in VIRUS EVOLUTION

Immortalized porcine mesenchymal cells derived from nasal mucosa, lungs, lymph nodes, spleen and bone marrow retain their stemness properties and trigger the expression of siglec-1 in co-cultured blood monocytic cells

Abubakar GarbaLowiese DesmaretsDelphine AcarBert DevriendtHans Nauwynck

A1 Journal Article in PLOS ONE

Invasion of equine and bovine alphaherpesviruses through the respiratory mucosa and interaction between equine herpes- and arteritis virus

Jing ZhaoHans Nauwynck

Invasion of feline, canine and porcine alphaherpesviruses through target mucosae of their respective host

Yewei LiHans Nauwynck

Long-term culture and differentiation of porcine red bone marrow hematopoietic cells co-cultured with immortalized mesenchymal cells

Abubakar GarbaDelphine AcarInge RoukaertsLowiese DesmaretsBert DevriendtHans Nauwynck

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Molecular cloning of porcine Siglec-3, Siglec-5 and Siglec-10, and identification of Siglec-10 as an alternative receptor for porcine reproductive and respiratory syndrome virus (PRRSV)

Jiexiong XieIsaura ChristiaensBo YangWander Van BreedamTingting CuiHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Monoclonal antibody binding to the macrophage-specific receptor sialoadhesin alters the phagocytic properties of human and mouse macrophages

Marjorie De SchryverDavie CappoenDirk ElewautHans NauwynckLouis MaesGuy CaljonPaul CosPeter L Delputte

A1 Journal Article in CELLULAR IMMUNOLOGY

Myelin sheath development in the maxillary nerve of the newborn pig

KV PapageorgiouI GrivasM ChiotelliE PanterisN PapaioannouHans NauwynckSK Kritas

A1 Journal Article in ANATOMIA HISTOLOGIA EMBRYOLOGIA

Outcome of highly pathogenic PRRSV1 subtype 3 in pigs immune after infection with PRRSV1 subtype 1 and after vaccination with commercial and new experimental attenuated vaccines

Ivan TrusHans Nauwynck

Presence of DNA extracellular traps but not MUC5AC and MUC5B mucin in mucoid plugs/casts of infectious laryngotracheitis virus (ILTV) infected tracheas of chickens

Vishwanatha Reddy Avalakuppa Papi ReddyIvan TrusHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Presence of DNA extracellular traps but not MUC5AC and MUC5B mucin in mucoid plugs/casts of infectious laryngotracheitis virus (ILTV) infected tracheas of chickens

Vishwanatha Reddy Avalakuppa Papi ReddyIvan TrusVenugopal NairHans Nauwynck

Primary replication and invasion of the bovine gammaherpesvirus BoHV-4 in the genital mucosae

Bo YangYewei LiOsvaldo Américo Bogado PascottiniJiexiong XieRuifang WeiGeert OpsomerHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Replication of neurovirulent equine herpesvirus type 1 (EHV-1) in CD172a+ monocytic cells

Kathlyn LavalJolien Van CleemputKatrien PoelaertIvy BrownHans Nauwynck

A1 Journal Article in COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

The complex co-translational processing of glycoprotein GP5 of type 1 porcine reproductive and respiratory syndrome virus

Bastian ThaaSusanne KauferSara A NeumannBernadett PeibstHans NauwynckEberhard KrauseMichael Veit

A1 Journal Article in VIRUS RESEARCH

Us3 and Us9 proteins contribute to the stromal invasion of bovine herpesvirus 1 in the respiratory mucosa

Jing ZhaoKatrien PoelaertLennert SteukersHerman FavoreelYewei LiShafiqul I ChowdhurySylvia van Drunen Littel-van den HurkBrigitte CaijHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

2016

Antibacterial and antiviral activity of different haemocyte subpopulations of Litopenaeus vannamei

Vo Van TuanHans Nauwynck

Better insights in the pathogenesis of cytomegalovirus (CMV) infection and CMV vaccination by the use of a new murine CMV infection model

Jun XiangHans Nauwynck

Characterization of a genetically heterogeneous porcine rotavirus C, and other viruses present in the fecal virome of a non-diarrheic Belgian piglet

Sebastiaan TheunsNádia Conceição-NetoMark ZellerElisabeth HeylenInge RoukaertsLowiese DesmaretsMarc Van RanstHans NauwynckJelle Matthijnssens

A1 Journal Article in INFECTION GENETICS AND EVOLUTION

Characterization of immune responses following homologous reinfection of pigs with European subtype 1 and 3 porcine reproductive and respiratory syndrome virus strains that differ in virulence

Eefke WeesendorpNorbert Stockhofe-ZurwiedenHans NauwynckDitta J Popma-De GraafJohanna MJ Rebel

A1 Journal Article in VETERINARY MICROBIOLOGY

Combining laboratory and mathematical models to infer mechanisms underlying kinetic changes in macrophage susceptibility to an RNA virus

Andrea Doeschl-WilsonAlison WilsonJens NielsenHans NauwynckAlan ArchibaldTahar Ait-Ali

A1 Journal Article in BMC SYSTEMS BIOLOGY

Development and characterization of new species cross-reactive anti-sialoadhesin monoclonal antibodies

Marjorie De SchryverHanne Van GorpInge HoebekeBauke De MaeyerKaren OomsIsabel PintelonLouis J MaesPaul CosHans NauwynckPeter L Delputte

A2 Journal Article in ANTIBODIES

Development and evaluation of antiviral immunoglobulin single variable domains for prophylaxis of rabies in mice

Sanne TerrynHans NauwynckSteven Van Gucht

Difference in replication of low-passage MCMV HaNa1 in BALB/c, C57BL/6 and NOD mice and role of different branches of immunity in susceptibility

Jun XiangShunchuan ZhangGeorges LeclercqHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Differences in Env and Gag protein expression patterns and epitope availability in feline immunodeficiency virus infected PBMC compared to infected and transfected feline model cell lines

Inge RoukaertsChris K GrantSebastiaan TheunsIsaura ChristiaensDelphine AcarSebastiaan Van BockstaelLowiese DesmaretsHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Differences in uptake and killing of pathogenic and non-pathogenic bacteria by haemocyte subpopulations of penaeid shrimp, Litopenaeus vannamei, (Boone)

Vo Van TuanJoão José Pereira Dantas Da Rocha LimaKhuong Van ThuongWenfeng LiKorneel GrauwetPeter BossierHans Nauwynck

A1 Journal Article in JOURNAL OF FISH DISEASES

Dual infections of equine herpesvirus 1 and equine arteritis virus in equine respiratory mucosa explants

Jing ZhaoHaileleul Negussie DubaleKathlyn LavalKatrien PoelaertHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Early events of canine herpesvirus 1 infections in canine respiratory and genital mucosae by the use of ex vivo models

Yewei LiHaileleul Negussie DubaleYu QiuVishwanatha Reddy Avalakuppa Papi ReddyBart MateusenHans Nauwynck

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

Effect of equine herpesvirus type 1 (EHV-1) infection of nasal mucosa epithelial cells on integrin alpha 6 and on different components of the basement membrane

Hossein Bannazadeh BaghiHans Nauwynck

A1 Journal Article in ARCHIVES OF VIROLOGY

Effects of acute change in salinity and moulting on the infection of white leg shrimp (Penaeus vannamei) with white spot syndrome virus upon immersion challenge

Khuong Van ThuongVo Van TuanWenfeng LiPatrick SorgeloosPeter BossierHans Nauwynck

A1 Journal Article in JOURNAL OF FISH DISEASES

Entry of equid herpesvirus 1 into CD172a+ monocytic cells

Kathlyn LavalHerman FavoreelJolien Van CleemputKatrien PoelaertIvy BrownBruno VerhasseltHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Equine CD172a+ monocytic cells, the 'Trojan horse' for equine herpesvirus type 1 (EHV-1) dissemination in the horse

Kathlyn LavalHans Nauwynck

Experimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte cultures

Lowiese DesmaretsBen VermeulenSebastiaan TheunsNádia Conceição-NetoMark ZellerInge RoukaertsDelphine AcarDominique OlyslaegersMarc Van RanstJelle Matthijnssens et al.

A1 Journal Article in SCIENTIFIC REPORTS

Experimental studies on the portal of entry of White spot syndrome virus in Penaeus vannamei

Khuong Van ThuongHans Nauwynck

Genome sequences of two pseudorabies virus strains isolated in Greece

Konstantinos V PapageorgiouNicolás M SuárezGavin S WilkieGeorge FilioussisNikolaos PapaioannouHans NauwynckAndrew J DavisonSpyridon K Kritas

A2 Journal Article in MICROBIOLOGY RESOURCE ANNOUNCEMENTS

Immunity raised by recent European subtype 1 PRRSV strains allows better replication of East European subtype 3 PRRSV strain Lena than that raised by an older strain

Ivan TrusIlias FrydasVishwanatha Reddy Avalakuppa Papi ReddyCaroline BonckaertYewei LiLise KvisgaardLars LarsenHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Infections of neonatal and adult mice with murine CMV HaNa1 strain upon oronasal inoculation: new insights in the pathogenesis of natural primary CMV infections

Jun XiangShunchuan ZhangHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Kinetic analysis of internalization of white spot syndrome virus by haemocyte subpopulations of penaeid shrimp, Litopenaeus vannamei (Boone), and the outcome for virus and cell

Vo Van TuanGaëtan De GryseKhuong Van ThuongPeter BossierHans Nauwynck

A1 Journal Article in JOURNAL OF FISH DISEASES

MCMV exploits the spleen as a transfer hub for systemic dissemination upon oronasal inoculation

Shunchuan ZhangJun XiangSebastiaan TheunsLowiese DesmaretsHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Modified-live PRRSV subtype 1 vaccine UNISTRAIN® PRRS provides a partial clinical and virological protection upon challenge with East European subtype 3 PRRSV strain Lena

Caroline BonckaertKaren van der MeulenIsaac Rodríguez-BallaràRafael Pedrazuela SanzMar Fenech MartinezHans Nauwynck

A2 Journal Article in PORCINE HEALTH MANAGEMENT

Novel insights in the pathogenesis of infectious laryngotracheitis and bronchitis viruses in chickens

Vishwanatha Reddy Avalakuppa Papi ReddyHans Nauwynck

Pathogenesis of the highly passaged MCMV Smith strain and low passaged HaNa1 strain in Balb/c mice mimicking natural infection upon oronasal inoculation

Shunchuan ZhangHans Nauwynck

Pattern of circulation of MCMV mimicking natural infection upon oronasal inoculation

Shunchuan ZhangJun XiangLowiese DesmaretsHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Per os infectivity of white spot syndrome virus (WSSV) in white-legged shrimp (Litopenaeus vannamei) and role of peritrophic membrane

Khuong Van ThuongVo Van TuanWenfeng LiPatrick SorgeloosPeter BossierHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Porcine semen as a vector for transmission of viral pathogens

Dominiek MaesAnn Van SoomRuth AppeltantIoannis ArsenakisHans Nauwynck

A1 Journal Article in THERIOGENOLOGY

Presence and characterization of pig group A and C rotaviruses in feces of Belgian diarrheic suckling piglets

Sebastiaan TheunsPhilip VytLowiese DesmaretsInge RoukaertsElisabeth HeylenMark ZellerJelle MatthijnssensHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Productive replication of nephropathogenic infectious bronchitis virus in peripheral blood monocytic cells, a strategy for viral dissemination and kidney infection in chickens

Vishwanatha Reddy Avalakuppa Papi ReddyIvan TrusLowiese DesmaretsYewei LiSebastiaan TheunsHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Pseudorabies virus glycoprotein gE triggers ERK1/2 phosphorylation and degradation of the pro-apoptotic protein Bim in epithelial cells

Maria Setas Lopes PontesCliff Van WaesbergheHans NauwynckBruno VerhasseltHerman Favoreel

A1 Journal Article in VIRUS RESEARCH

Replication characteristics of eight virulent and two attenuated genotype 1 and 2 porcine reproductive and respiratory syndrome virus (PRRSV) strains in nasal mucosa explants

Ilias FrydasHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Replication characteristics of equine herpesvirus 1 and equine herpesvirus 3: comparative analysis using ex vivo tissue cultures

Haileleul Negussie DubaleYewei LiTesfaye Sisay TessemaHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Th2 biased upper airway inflammation is associated with an impaired response to viral infection with Herpes simplex virus 1

Feng LanXiang Dong WaneHans NauwynckGabriële HoltappelsLuo ZhangSebastian L JohnstonNikolaos G PapadopoulosClaus BachertNan Zhang

A1 Journal Article in RHINOLOGY

The US3 protein of pseudorabies virus drives viral passage across the basement membrane in porcine respiratory mucosa explants

Jochen LamoteSarah GlorieuxHans NauwynckHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

Upregulation of endothelial cell adhesion molecules characterizes veins close to granulomatous infiltrates in the renal cortex of cats with feline infectious peritonitis and is indirectly triggered by feline infectious peritonitis virus-infected monocytes in vitro

Delphine AcarDominique OlyslaegersAnnelike DedeurwaerderInge RoukaertsWendy BaetensSebastiaan Van BockstaelGaëtan De GryseLowiese DesmaretsHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

2015

A critical assessment of the effect of serine protease inhibitors on porcine fertilization and quality parameters of porcine spermatozoa in vitro

Josine BeekDominiek MaesHans NauwynckSofie PiepersAnn Van Soom

A1 Journal Article in REPRODUCTIVE BIOLOGY

A murine model for natural primary CMV infections: age-dependent differences in the replication kinetics of murine CMV HaNa1 isolate in BALB/c mice

Jun XiangShunchuan ZhangHans Nauwynck

A sequence of basic residues in the porcine circovirus type 2 capsid protein is crucial for its co-expression and co-localization with the replication protein

Liping HuangNicolaas Van RenneChangming LiuHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Circulation of pig group A and C rotaviruses in Belgian diarrheic suckling pigs and its impact on veterinary diagnostically analyses

Sebastiaan TheunsPhilip VytLowiese DesmaretsInge RoukaertsElisabeth HeylenMark ZellerMarc Van RanstJelle MatthijnssensHans Nauwynck

Comparison of in/ex vivo replication characteristics of different porcine reproductive and respiratory syndrome virus strains

Ilias FrydasHans Nauwynck

Comparison of the pathogenesis of the highly passaged MCMV Smith strain with that of the low passaged MCMV HaNa1 isolate in BALB/c mice upon oronasal inoculation

Shunchuan ZhangJun XiangJan Van DoorsselaereHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Complete genome characterization of recent and ancient Belgian pig group A rotaviruses and assessment of their evolutionary relationship with human rotaviruses

Sebastiaan TheunsElisabeth HeylenMark ZellerInge RoukaertsLowiese DesmaretsMarc Van RanstHans NauwynckJelle Matthijnssens

Complete genome characterization of recent and ancient Belgian pig group A rotaviruses and assessment of their evolutionary relationship with human rotaviruses

Sebastiaan TheunsElisabeth HeylenMark ZellerInge RoukaertsLowiese DesmaretsMarc Van RanstHans NauwynckJelle Matthijnssens

A1 Journal Article in JOURNAL OF VIROLOGY

Complete genome sequence of a porcine epidemic diarrhea virus from a novel outbreak in Belgium, January 2015

Sebastiaan TheunsNádia Conceição-NetoIsaura ChristiaensMark ZellerLowiese DesmaretsInge RoukaertsDelphine AcarElisabeth HeylenJelle MatthijnssensHans Nauwynck

A2 Journal Article in MICROBIOLOGY RESOURCE ANNOUNCEMENTS

Development of primary and secondary cell cultures from the lymphoid organ of Penaeus vannamei to study the replication cycle of white spot syndrome virus (WSSV)

Wenfeng LiHans Nauwynck

Different clinical, virological, serological and tissue tropism outcomes of two new and one old Belgian type 1 subtype 1 porcine reproductive and respiratory syndrome virus (PRRSV) isolates

Ilias FrydasIvan TrusLise KvisgaardCaroline BonckaertVishwanatha Reddy Avalakuppa Papi ReddyYewei LiLars LarsenHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Effects of EHV-1 infection on the migration behavior of monocytic cells and on components of the basement membrane in the respiratory mucosa

Hossein Bannazadeh BaghiHans Nauwynck

Equine herpesvirus type 1 enhances viral replication in CD172a⁺ monocytic cells upon adhesion to endothelial cells

Kathlyn LavalHerman FavoreelKatrien PoelaertJolien Van CleemputHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

Equine herpesvirus type 1 replication is delayed in CD172a⁺ monocytic cells and controlled by histone deacetylases

Kathlyn LavalHerman FavoreelHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Ex vivo modeling of feline herpesvirus replication in ocular and respiratory mucosae, the primary targets of infection

Yewei LiJolien Van CleemputYu QiuVishwanatha Reddy Avalakuppa Papi ReddyBart MateusenHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Eye extract improves cell migration out of lymphoid organ explants of L-vannamei and viability of the primary cell cultures

Wenfeng LiVo Van TuanKhuong Van ThuongPeter BossierHans Nauwynck

A1 Journal Article in IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Fecal virome analysis from a diarrhea outbreak in Belgian fattening pigs reveals novel divergent porcine picobirnaviruses

Nadia Conceição-NetoSebastiaan TheunsKwe Claude YindaMark ZellerElisabeth HeylenIsaura ChristiaensLowiese DesmaretsInge RoukaertsDelphine AcarMarc Van Ranst et al.

Genetic characterization of the Belgian nephropathogenic infectious bronchitis virus (NIBV) reference strain B1648

Vishwanatha Reddy Avalakuppa Papi ReddySebastiaan TheunsInge RoukaertsMark ZellerJelle MatthijnssensHans Nauwynck

A1 Journal Article in VIRUSES-BASEL

Genome sequencing by random priming methods for viral identification

Toon RosseelSteven Van BormHans Nauwynck

Inhibitors of serine proteases decrease sperm penetration during porcine fertilization in vitro by inhibiting sperm binding to the zona pellucida and acrosome reaction

Josine BeekHans NauwynckRuth AppeltantDominiek MaesAnn Van Soom

A1 Journal Article in THERIOGENOLOGY

Interactions of pseudorabies virus and swine influenza virus with porcine respiratory mucus

Xiaoyun YangHans NauwynckKristien Van Reeth

MCMV exploits the spleen as a transfer hub for systemic dissemination upon oronasal inoculation

Shunchuan ZhangJun XiangSebastiaan TheunsLowiese DesmaretsHans Nauwynck

Novel insights in the role of proteases during porcine fertilization in vitro

Josine BeekAnn Van SoomDominiek MaesHans Nauwynck

Phylogenetic analysis of feline immunodeficiency virus strains from naturally infected cats in Belgium and The Netherlands

Inge RoukaertsSebastiaan TheunsElien TaffinSylvie DaminetHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Porcine rotavirus infections in Belgian piglets and assessment of their evolutionary relationship with human rotaviruses

Sebastiaan TheunsHans NauwynckJelle Matthijnssens

Replication characteristics of respiratory and nephrophathogenic infectious bronchitis virus (IBV) strains M41 and B1648 in respiratory mucosa and monocytes

Vishwanatha Reddy Avalakuppa Papi ReddyIvan TrusYewei LiHans Nauwynck

Sensitivity of porcine epidemic diarrhea virus (PEDV) to pH and heat treatment in the presence or absence of porcine plasma

Galyna RybachukHans NauwynckID Kalmar

A1 Journal Article in VETERINARY MICROBIOLOGY

Successive subclinical group A rotavirus infections in piglets after weaning on a closed Belgian pig farm

Sebastiaan TheunsLowiese DesmaretsInge RoukaertsIsaura ChristiaensElisabeth HeylenMark ZellerMarc Van RanstJelle MatthijnssensHans Nauwynck

Systemic dissemination of MCMV HaNa1 via non-productively infected leukocytes between nose, lymphoid organs and salivary glands upon oronasal exposure

Shunchuan ZhangJun XiangLowiese DesmaretsHans Nauwynck

The fecal virome of a Belgian non-diarrheic piglet contains group A and C rotaviruses, and an astro- and enterovirus

Sebastiaan TheunsNadia Conceição-NetoElisabeth HeylenMark ZellerInge RoukaertsLowiese DesmaretsMarc Van RanstHans NauwynckJelle Matthijnssens

The immunity raised by recent European subtype 1 PRRSV strains allows a better replication of East European subtype 3 PRRSV strain Lena than the immunity raised by an older strain: increased risk for spatial expansion of PRRSV Lena-like strains

Ivan TrusIlias FrydasVishwanatha Reddy Avalakuppa Papi ReddyCaroline BonckaertYewei LiLise K KvisgaardLars E LarsenHans Nauwynck

The invasion mechanisms of infectious laryngotracheitis virus (ILTV) in the respiratory and conjunctival mucosa

Vishwanatha Reddy Avalakuppa Papi ReddyIvan TrusYewei LiHans Nauwynck

Tracing back roots: unravelling feline enteric coronavirus pathogenesis to combat feline infectious peritonitis

Lowiese DesmaretsHans Nauwynck

Virus replication cycle of white spot syndrome virus in secondary cell cultures from the lymphoid organ of Litopenaeus vannamei

Wenfeng LiLowiese DesmaretsGaëtan De GryseSebastiaan TheunsVo Van TuanKhuong Van ThuongPeter BossierHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Vpx-independent lentiviral transduction and shRNA-mediated protein knock-down in monocyte-derived dendritic cells

Wojciech WitkowskiJolien VermeireAlessia LandiEvelien NaessensHanne VanderstraetenHans NauwynckHerman FavoreelBruno Verhasselt

A1 Journal Article in PLOS ONE

2014

A beneficiary role for neuraminidase in influenza virus penetration through the respiratory mucus

Xiaoyun YangLennert SteukersKatrien ForierRanhua XiongKevin BraeckmansKristien Van ReethHans Nauwynck

A1 Journal Article in PLOS ONE

Bitter-sweet symphony: glycan–lectin interactions in virus biology

Wander Van BreedamStefan PöhlmannHerman FavoreelRaoul de GrootHans Nauwynck

A1 Journal Article in FEMS MICROBIOLOGY REVIEWS

Boosting in planta production of antigens derived from the porcine reproductive and respiratory syndrome virus (PRRSV) and subsequent evaluation of their immunogenicity

Robin PironStefaan De KokerAnnelies De PaepeJulie GoossensJohan GrootenHans NauwynckAnna Depicker

A1 Journal Article in PLOS ONE

Changing receptor use of PRRSV leads to different virological, immunological and clinical outcome: impact on diagnosis and control

Hans NauwynckIlias FrydasIsaura ChristiaensWander Van BreedamCaroline BonckaertIvan Trus

Characterization of a primary cell culture from lymphoid organ of Litopenaeus vannamei and use for studies on WSSV replication

Wenfeng LiVan Thao NguyenMathias CorteelJoão José Pereira Dantas Da Rocha LimaKhuong Van ThuongVo Van TuanPeter BossierPatrick SorgeloosHans Nauwynck

A1 Journal Article in AQUACULTURE

Comparison of the pathogenesis of the highly passaged MCMV Smith strain with that of low passaged MCMV HaNa1 strain in Balb/c mice upon oronasal inoculation

Shunchuan ZhangJun XiangHans Nauwynck

Comparison of the pathogenesis of the highly passaged MCMV Smith strain with that of the low passaged MCMV HaNa1 strain in Balb/c mice upon oronasal inoculation

Shunchuan ZhangJun XiangHans Nauwynck

Complete genome characterization of recent and ancient Belgian pig group A rotaviruses and assessment of their evolutionary relationship with human rotaviruses

Sebastiaan TheunsElisabeth HeylenMark ZellerInge RoukaertsLowiese DesmaretsMarc Van RanstHans NauwynckJelle Matthijnssens

Detection of total and PRRSV-specific antibodies in oral fluids collected with different rope types from PRRSV-vaccinated and experimentally infected pigs

Inge DecorteWander Van BreedamYves Van der StedeHans NauwynckNick De ReggeAnn Brigitte Cay

A1 Journal Article in BMC VETERINARY RESEARCH

Efficacy of an attenuated European subtype 1 porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in pigs upon challenge with the East European subtype 3 PRRSV strain Lena

Ivan TrusCaroline BonckaertKaren van der MeulenHans Nauwynck

A1 Journal Article in VACCINE

Efficacy of an attenuated European subtype 1 porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in pigs upon challenge with the East European subtype 3 PRRSV strain Lena

Ivan TrusCaroline BonckaertKaren van der MeulenHans Nauwynck

Establishment of feline intestinal epithelial cell cultures for the propagation and study of feline enteric coronaviruses

Lowiese DesmaretsSebastiaan TheunsDominique OlyslaegersAnnelike DedeurwaerderBen VermeulenInge RoukaertsHans Nauwynck

Feline infectious peritonitis virus accessory proteins and type I interferon are fighting for dominance

Annelike DedeurwaerderHans Nauwynck

Impact of equine herpesvirus type 1 (EHV-1) infection on the migration of monocytic cells through equine nasal mucosa

Hossein Bannazadeh BaghiHans Nauwynck

A1 Journal Article in COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

Isolation and characterization of equine nasal mucosal CD172a⁺ cells

Hossein Bannazadeh BaghiKathlyn LavalHerman FavoreelHans Nauwynck

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Mimicking herpes simplex virus 1 and herpes simplex virus 2 mucosal behavior in a well characterized human genital organ culture

Lennert SteukersSteven WeyersXiaoyun YangAnnelies VandekerckhoveSarah GlorieuxMaria CornelissenWim Van Den BroeckMarleen TemmermanHans Nauwynck

A1 Journal Article in JOURNAL OF INFECTIOUS DISEASES

Myosins 1 and 6, myosin light chain kinase, actin and microtubules cooperate during antibody-mediated internalisation and trafficking of membrane-expressed viral antigens in feline infectious peritonitis virus infected monocytes

Hannah DewerchinLowiese DesmaretsYtse NoppeHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

ORF7-encoded accessory protein 7a of feline infectious peritonitis virus as a counteragent against IFN-α-induced antiviral response

Annelike DedeurwaerderDominique OlyslaegersLowiese DesmaretsInge RoukaertsSebastiaan TheunsHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

ORF7-encoded accessory protein 7a of feline infectious peritonitis virus as a counteragent against IFN-α-induced antiviral response

Annelike DedeurwaerderDelphine AcarDominique OlyslaegersLowiese DesmaretsInge RoukaertsSebastiaan TheunsHans Nauwynck

Performance of assays for testing antibodies against porcine reproductive and respiratory syndrome virus in sera collected from swine farms in a region with an extreme virus heterogeneity

U Uladzimir KarniychukHans Nauwynck

A1 Journal Article in ACTA VETERINARIA-BEOGRAD

Phylogenetic analysis of FIV strains from naturally infected cats in Belgium and the Netherlands

Inge RoukaertsSebastiaan TheunsElien TaffinSylvie DaminetHans Nauwynck

Phylogenetic analysis of FIV strains from naturally infected cats in Belgium and the Netherlands.

Inge RoukaertsSebastiaan TheunsElien TaffinSylvie DaminetHans Nauwynck

Porcine group A rotaviruses with heterogeneous VP7 and VP4 genotype combinations can be found together with enteric bacteria on Belgian swine farms

Sebastiaan TheunsLowiese DesmaretsElisabeth HeylenMark ZellerAnnelike DedeurwaerderInge RoukaertsMarc Van RanstJelle MatthijnssensHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

RNA-Sequence analysis of primary alveolar macrophages after in vitro infection with porcine reproductive and respiratory syndrome virus strains of differing virulence

Bouabid BadaouiTeresa RutiglianoAnna AnselmoMerijn VanheeHans NauwynckElisabetta GiuffraSara Botti

A1 Journal Article in PLOS ONE

Replication characteristics of infectious laryngotracheitis virus in the respiratory and conjunctival mucosa

Vishwanatha Reddy Avalakuppa Papi ReddyLennert SteukersYewei LiWalter FuchsAlain VanderplasschenHans Nauwynck

A1 Journal Article in AVIAN PATHOLOGY

Role of sialic acids in feline enteric coronavirus infections

Lowiese DesmaretsSebastiaan TheunsInge RoukaertsDelphine AcarHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Role of sialic acids in feline enteric coronaviruses infections

Lowiese DesmaretsSebastiaan TheunsInge RoukaertsDelphine AcarHans Nauwynck

The immunity raised by recent European subtype 1 porcine reproductive and respiratory syndrome virus (PRRSV) strains allows spatial expansion of highly virulent East European subtype 3 PRRSV strains

Ivan TrusIlias FrydasCaroline BonckaertVishwanatha Reddy Avalakuppa Papi ReddyYewei LiLise KvisgaardLars LarsenHans Nauwynck

The intriguing game of porcine reproductive and respiratory syndrome virus with different macrophage subsets determines the virological and clinical outcome

Hans NauwynckIlias FrydasIvan TrusIsaura ChristiaensCaroline BonckaertWander Van Breedam

The recent European isolate (08P178) of equine arteritis virus causes inflammation but not arteritis in experimentally infected ponies

Sabrina VairoVeronique SaeyC BombardiRichard DucatelleHans Nauwynck

A1 Journal Article in JOURNAL OF COMPARATIVE PATHOLOGY

The role of leukocyte extravasation in the pathogenesis of feline infectious peritonitis

Dominique OlyslaegersHans NauwynckHannah L Dewerchin

Unraveling the role of porcine group A rotaviruses in the pathogenesis of piglet diarrhea and assessment of their genetic constellation

Sebastiaan TheunsLowiese DesmaretsElisabeth HeylenMark ZellerAnnelike DedeurwaerderInge RoukaertsMarc Van RanstJelle MatthijnssensHans Nauwynck

2013

Adaptable inactivated vaccine for combating Porcine Reproductive and Respiratory Syndrome Virus

Marc GeldhofHans NauwynckWander Van Breedam

Altered expression of adhesion molecules on peripheral blood leukocytes in feline infectious peritonitis

Dominique OlyslaegersAnnelike DedeurwaerderLowiese DesmaretsBen VermeulenHannah DewerchinHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Antibody response and maternal immunity upon boosting PRRSV-immune sows with experimental farm-specific and commercial PRRSV vaccines

Marc GeldhofWander Van BreedamEllen De JongAlfonso Lopez RodriguezUladzimir KarniychukMerijn VanheeJan Van DoorsselaereDominiek MaesHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Complete genome analysis of Belgian porcine rotaviruses reveals a rather conserved porcine-like genotype constellation, despite large genetic diversity of VP7 and VP4

Sebastiaan TheunsElisabeth HeylenMark ZellerMarc Van RanstJelle MatthijnssensHans Nauwynck

Contrasting replication of feline enteric coronavirus and feline infectious peritonitis virus in newly established feline intestinal epithelial cell cultures

Lowiese DesmaretsSebastiaan TheunsDominique OlyslaegersAnnelike DedeurwaerderBen VermeulenHannah DewerchinHans Nauwynck

Development and use of a polarized equine upper respiratory tract mucosal explant system to study the early phase of pathogenesis of a European strain of equine arteritis virus

Sabrina VairoWim Van Den BroeckHerman FavoreelAlessandra ScagliariniHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Development of a recombinant antibody to target peptides and proteins to sialoadhesin-expressing macrophages

Karen OomsHanne Van GorpTim Van GaeverHans NauwynckPeter Delputte

A1 Journal Article in BMC BIOTECHNOLOGY

Development of techniques to culture shrimp haemocytes and purify white spot syndrome virus (WSSV) in order to study WSSV-haemocyte interactions

João José Pereira Dantas Da Rocha LimaHans NauwynckPatrick Sorgeloos

Development of two reproducible haemocyte culture systems for application in crustacean immunity studies

João José Pereira Dantas Da Rocha LimaMathias CorteelDangh OanhPeter BossierPatrick SorgeloosHans Nauwynck

Diagnosis of porcine rotavirus infections by RT-qPCR and RT-PCR reveals a possible synergism between enteric bacteria and genetically heterogeneous porcine rotaviruses in Belgium

Sebastiaan TheunsLowiese DesmaretsElisabeth HeylenMark ZellerAnnelike DedeurwaerderMarc Van RanstJelle MatthijnssensHans Nauwynck

Effect of saliva stabilisers on detection of porcine reproductive and respiratory syndrome virus in oral fluid by quantitative reverse transcriptase real-time PCR

Inge DecorteYves Van der StedeHans NauwynckNick De ReggeAnn Brigitte Cay

A1 Journal Article in VETERINARY JOURNAL

Equine viral arteritis : in vivo and ex vivo pathogenesis of a European isolate

Sabrina VairoHans NauwynckA. Scagliarini

Establishment of feline intestinal epithelial cell cultures for the propagation and study of feline enteric coronaviruses

Lowiese DesmaretsSebastiaan TheunsDominique OlyslaegersAnnelike DedeurwaerderBen VermeulenInge RoukaertsHans Nauwynck

Establishment of feline intestinal epithelial cell cultures for the propagation and study of feline enteric coronaviruses

Lowiese DesmaretsSebastiaan TheunsDominique OlyslaegersAnnelike DedeurwaerderBen VermeulenInge RoukaertsHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Evaluation of viral peptide targeting to porcine sialoadhesin using a porcine reproductive and respiratory syndrome virus vaccination-challenge model

Karen OomsHanne Van GorpSara BottiTim Van GaeverPeter DelputteHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Feline peripheral blood mononuclear cell cultivation: cell population evolution, FIV receptor expression, and FIV replication

Inge RoukaertsDominique OlyslaegersLowiese DesmaretsSebastiaan TheunsAnnelike DedeurwaerderHans Nauwynck

Generation and characterization of feline arterial and venous endothelial cell lines for the study of the vascular endothelium

Dominique OlyslaegersLowiese DesmaretsAnnelike DedeurwaerderHannah DewerchinHans Nauwynck

A1 Journal Article in BMC VETERINARY RESEARCH

Identification of target cells of a European equine arteritis virus strain in experimentally infected ponies

Sabrina VairoHerman FavoreelA ScagliariniHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Nulla tenaci invia est via : unraveling herpesvirus mucosal invasion in an ex vivo organ culture

Lennert SteukersHans Nauwynck

ORF7-encoded accessory protein 7a of feline infectious peritonitis virus as a counteragent against IFN-α-induced antiviral response

Annelike DedeurwaerderDominique OlyslaegersLowiese DesmaretsInge RoukaertsSebastiaan TheunsHans Nauwynck

Pathogenesis and prevention of placental and transplacental porcine reproductive and respiratory syndrome virus infection

Uladzimir KarniychukHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Porcine reproductive and respiratory syndrome virus infection is associated with an increased number of Sn-positive and CD8-positive cells in the maternal-fetal interface

Uladzimir KarniychukWard De SpiegelaereHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Porcine, murine and human sialoadhesin (Sn/Siglec-1/CD169): portals for porcine reproductive and respiratory syndrome virus entry into target cells

Wander Van BreedamMieke VerbeeckIsaura ChristiaensHanne Van GorpHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Purification of white spot syndrome virus by iodixanol density gradient centrifugation

João José Pereira Dantas Da Rocha LimaMathias CorteelMaria CornelissenPeter BossierPatrick SorgeloosHans Nauwynck

A1 Journal Article in JOURNAL OF FISH DISEASES

Replication characteristics of porcine reproductive and respiratory syndrome virus (PRRSV) European subtype 1 (Lelystad) and subtype 3 (Lena) strains in nasal mucosa and cells of the monocytic lineage: indications for the use of new receptors of PRRSV (Lena)

Ilias FrydasMieke VerbeeckJun CaoHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Separation of Penaeus vannamei haemocyte subpopulations by iodixanol density gradient centrifugation

João José Pereira Dantas Da Rocha LimaVo Van TuanMathias CorteelKorneel GrauwetNTT AnPatrick SorgeloosHans Nauwynck

A1 Journal Article in AQUACULTURE

Suppression of NK cell-mediated cytotoxicity against PRRSV-infected porcine alveolar macrophages in vitro

Jun CaoKorneel GrauwetBen VermeulenBert DevriendtPing JiangHerman FavoreelHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Suppression of NK cell-mediated cytotoxicity and immunoenhancement of CD40 ligand against porcine reproductive and respiratory syndrome virus

Jun CaoPing JiangHans Nauwynck

Suppression of NK cells and regulatory T lymphocytes in cats naturally infected with feline infectious peritonitis virus

Ben VermeulenBert DevriendtDominique OlyslaegersAnnelike DedeurwaerderLowiese DesmaretsHerman FavoreelHannah DewerchinHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Targeting antigens to sialoadhesin-expressing macrophages as a vaccination strategy

Karen OomsPeter DelputteHans Nauwynck

The pathogenesis of porcine reproductive and respiratory syndrome (PRRS) is fully determined by the intriguing interplay of PRRSV with monocytic cells

Hans NauwynckUladzimir KarniychukMieke VerbeeckIsaura ChristiaensIvan TrusJun CaoIlias FrydasWander Van Breedam

The role of accessory proteins in the replication of feline infectious peritonitis virus in peripheral blood monocytes

Annelike DedeurwaerderLowiese DesmaretsDominique OlyslaegersBen VermeulenHannah DewerchinHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

The role of cell-mediated immunity during coronavirus infections in cats : opportunities for therapeutic avenues?

Ben VermeulenHans Nauwynck

Use of Staby® technology for development and production of DNA vaccines free of antibiotic resistance gene

Anca ReschnerSophie ScohyGaëlle VandermeulenMarc DaukandtCéline JacquesBenjamin MichelHans NauwynckFlorence XhonneuxVéronique PréatAlain Vanderplasschen et al.

A1 Journal Article in HUMAN VACCINES & IMMUNOTHERAPEUTICS

Use of a new RT-qPCR assay for diagnosis of genetically heterogeneous porcine group A rotaviruses in Belgium reveals a possible synergism with enteric bacteria

Sebastiaan TheunsLowiese DesmaretsElisabeth HeylenMark ZellerAnnelike DedeurwaerderMarc Van RanstJelle MatthijnssensHans Nauwynck

White spot syndrome virus infection in P. vannamei and M. rosenbergii : experimental studies on susceptibility to infection and disease

Mathias CorteelHans NauwynckPatrick SorgeloosVictoria Alday-Sanz

2012

Antigenic characterisation of porcine circovirus 2 strains and outcome of experimental porcine circovirus 1 and 2 infections in porcine foetuses and in pigs

Dipongkor SahaHans Nauwynck

Antigenic subtyping and epitopes' competition analysis of porcine circovirus type 2 using monoclonal antibodies

Dipongkor SahaLiping HuangEva BussalleuDavid LefebvreMaria FortJan Van DoorsselaereHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Cell tropism and entry of porcine circovirus 2

Hans NauwynckR SanchezPeter MeertsDavid LefebvreDipongkor SahaLiping HuangG Misinzo

A1 Journal Article in VIRUS RESEARCH

Clinical and virological outcome of an infection with the Belgian equine arteritis virus strain 08P178

Sabrina VairoAnnelies VandekerckhoveLennert SteukersSarah GlorieuxWim Van Den BroeckHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Comparison of the efficacy of autogenous inactivated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccines with that of commercial vaccines against homologous and heterologous challenges

Marc GeldhofMerijn VanheeWander Van BreedamJan Van DoorsselaereUladzimir KarniychukHans Nauwynck

A1 Journal Article in BMC VETERINARY RESEARCH

Complete genome characterization of a East European Type 1 subtype 3 porcine reproductive and respiratory syndrome virus

Jan Van DoorsselaereMS BrarM ShiUladzimir KarniychukFCC LeungHans Nauwynck

A1 Journal Article in VIRUS GENES

Congenital porcine reproductive and respiratory syndrome virus infection in naïve and vaccinated sows

Uladzimir KarniychukHans Nauwynck

Contrasting replication kinetics of feline enteric coronavirus and feline infectious peritonitis virus in newly established feline intestinal epithelial cell cultures

Lowiese DesmaretsSebastiaan TheunsDominique OlyslaegersAnnelike DedeurwaerderBen VermeulenHannah DewerchinHans Nauwynck

Demonstration of microchimerism in pregnant sows and effects of congenital PRRSV infection

Uladzimir KarniychukWander Van BreedamNadine Van RoyClaire Rogel-GaillardHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Demonstration of microchimerism in pregnant sows and fetuses and putative microchimerism involvement in the pathogenesis of congenital PRRSV infection

Uladzimir KarniychukWander Van BreedamNadine Van RoyC Rogel-GaillardHans Nauwynck

Development of two haemocyte culture systems (in attachment and in suspension) for shrimp immunity studies

João José Pereira Dantas Da Rocha LimaMathias CorteelDTH OanhPeter BossierPatrick SorgeloosHans Nauwynck

A1 Journal Article in AQUACULTURE

Diverse microbial interactions with the basement membrane barrier

Lennert SteukersSarah GlorieuxAnnelies VandekerckhoveHerman FavoreelHans Nauwynck

A1 Journal Article in TRENDS IN MICROBIOLOGY

Evaluation of the antiviral activity of (1'S,2'R)-9-[[1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl]guanine (A-5021) against equine herpesvirus type 1 in cell monolayers and equine nasal mucosal explants

Sarah GlorieuxAnnelies VandekerckhoveNesya GorisXiaoyun YangLennert SteukersGerlinde Van de WalleSiska CroubelsJohan NeytsHans Nauwynck

A1 Journal Article in ANTIVIRAL RESEARCH

Expression of late viral proteins is restricted in nasal mucosal leucocytes but not in epithelial cells during early-stage equine herpes virus-1 infection

Annick GryspeerdtAnnelies VandekerckhoveHossein Bannazadeh BaghiGerlinde Van de WalleHans Nauwynck

A1 Journal Article in VETERINARY JOURNAL

Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue

XiangDong WangNan ZhangSarah GlorieuxGabriële HoltappelsMario VaneechoutteOlga KryskoLuo ZhangDeMin HanHans NauwynckClaus Bachert

A1 Journal Article in PLOS ONE

Immobilization of pseudorabies virus in porcine tracheal respiratory mucus revealed by single particle tracking

Xiaoyun YangKatrien ForierLennert SteukersSandra Van VlierberghePeter DubruelKevin BraeckmansSarah GlorieuxHans Nauwynck

A1 Journal Article in PLOS ONE

Impact of a novel inactivated PRRS virus vaccine on virus replication and virus-induced pathology in fetal implantation sites and fetuses upon challenge

Uladzimir KarniychukDipongkor SahaMerijn VanheeMarc GeldhofPieter CornillieAB CaijNick De ReggeHans Nauwynck

A1 Journal Article in THERIOGENOLOGY

In vitro assessment of the feline cell-mediated immune response against feline panleukopeniavirus, calicivirus and felid herpesvirus 1 using 5-bromo-2'-deoxyuridine labeling

Ben VermeulenSabine GleichAnnelike DedeurwaerderDominique OlyslaegersLowiese DesmaretsHannah DewerchinHans Nauwynck

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Inactivated virus vaccines from chemistry to prophylaxis: merits, risks and challenges

Iris DelrueDieter VerzeleAnnemieke MadderHans Nauwynck

A1 Journal Article in EXPERT REVIEW OF VACCINES

Inhibitors of zinc-dependent metalloproteases hinder sperm passage through the cumulus oophorus during porcine fertilization in vitro

Josine BeekHans NauwynckDominiek MaesAnn Van Soom

A1 Journal Article in REPRODUCTION

Instability in vitro of a PCV2 infectious clone containing an insertion between ORF1 and ORF2

Dipongkor SahaJan Van DoorsselaereHans Nauwynck

A1 Journal Article in VIRUS GENES

Interaction of the European genotype porcine reproductive and respiratory syndrome virus (PRRSV) with sialoadhesin (CD169/Siglec-1) inhibits alveolar macrophage phagocytosis

Miet De BaereHanne Van GorpPeter DelputteHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Kinetics of BoHV-1 dissemination in an in vitro culture of bovine upper respiratory tract mucosa explants

Lennert SteukersAnnelies VandekerckhoveWim Van Den BroeckSarah GlorieuxHans Nauwynck

A1 Journal Article in ILAR JOURNAL

Micro-dissecting the pathogenesis and immune response of PRRSV infection paves the way for more efficient PRRSV vaccines

Hans NauwynckHanne Van GorpMerijn VanheeUladzimir KarniychukMarc GeldhofJun CaoMieke VerbeeckWander Van Breedam

A1 Journal Article in TRANSBOUNDARY AND EMERGING DISEASES

Moult cycle of laboratory-raised Penaeus (Litopenaeus) vannamei and P. monodon

Mathias CorteelJoão José Pereira Dantas Da Rocha LimaMathieu WilleV Alday-SanzMaurice PensaertPatrick SorgeloosHans Nauwynck

A1 Journal Article in AQUACULTURE INTERNATIONAL

Natural killer cells: frequency, phenotype and function in healthy cats

Ben VermeulenBert DevriendtDominique OlyslaegersAnnelike DedeurwaerderLowiese DesmaretsKorneel GrauwetHerman FavoreelHannah DewerchinHans Nauwynck

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Novel insights in the physiological function of sialoadhesin as a downregulator of macrophage phagocytosis and its implications for viral infection

Miet De BaereHans NauwynckPeter Delputte

Porcine sialoadhesin: a newly identified xenogeneic innate immune receptor

LG BrockPeter DelputteJP WaldmanHans NauwynckMA Rees

A1 Journal Article in AMERICAN JOURNAL OF TRANSPLANTATION

Quantitative analysis of an anti-viral immune escape compound ML-7 in feline plasma using ultra performance liquid chromatography/electrospray ionization mass spectrometry

Marc CherletSabine GleichHannah DewerchinHans NauwynckSylvie DaminetPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Schmallenberg virus: emergence of an Orthobunyavirus among ruminants in Western Europe

Lennert SteukersGuido BertelsAnn Brigitte CayHans Nauwynck

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Single amino acid mutations in the capsid switch the neutralization phenotype of porcine circovirus 2

Dipongkor SahaDavid LefebvreKaren OomsLiping HuangPeter DelputteJan Van DoorsselaereHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Susceptibility of juvenile Macrobrachium rosenbergii to different doses of high and low virulence strains of white spot syndrome virus (WSSV)

Mathias CorteelJoão José Pereira Dantas Da Rocha LimaVo Van TuanKhuong Van ThuongMathieu WilleVictoria Alday-SanzMaurice PensaertPatrick SorgeloosHans Nauwynck

A1 Journal Article in DISEASES OF AQUATIC ORGANISMS

The pig: a model for human infectious diseases

François MeurensArtur SummerfieldHans NauwynckLinda SaifVolker Gerdts

A1 Journal Article in TRENDS IN MICROBIOLOGY

The role of accessory proteins in the replication of feline infectious peritonitis virus in peripheral blood monocytes

Annelike DedeurwaerderLowiese DesmaretsDominique OlyslaegersBen VermeulenHannah DewerchinHans Nauwynck

The role of regulatory T cells during infection with feline infectious peritonitis virus

Ben VermeulenLowiese DesmaretsAnnelike DedeurwaerderDominique OlyslaegersHannah DewerchinHans Nauwynck

The role of vaccines for PRRS control and PRRSV eradication

Hans NauwynckIvan TrusIsaura ChristiaensUladzimir KarniychukIlias FrydasJun CaoWander Van Breedam

Third international Havemeyer workshop on equine herpesvirus type 1 (EHV-1)

Julia KiddJosh SlaterNikolaus OsterriederDavid LunnDoug AntczakWalid AzabUdeni BalasuriyaCyril BarnettMargaret BrosnahanCorrey Cook et al.

Editorial material

2011

A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosa

Sarah GlorieuxHerman FavoreelLennert SteukersAnnelies VandekerckhoveHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Antibody binding to porcine sialoadhesin reduces phagocytic capacity without affecting other macrophage effector functions

Miet De BaereHanne Van GorpHans NauwynckPeter Delputte

A1 Journal Article in CELLULAR IMMUNOLOGY

Antigenic differences among PCV2 strains of different genetic clusters as demonstrated by the use of monoclonal antibodies generated against PCV2A or PCV2B

Dipongkor SahaE BussalleuDavid LefebvreM FortTomas CsankJ Van DoorsselaereHans Nauwynck

Antigenic profiling of the porcine reproductive and respiratory syndrome virus

Merijn VanheeHans Nauwynck

Aujeszky's disease (pseudorabies): an old threat in current pig industry?, part I : pathogenetic information and implications

KV PapageorgiouAR BurrielG FilioussisV PsychasHans NauwynckSK Kritas

A1 Journal Article in JOURNAL OF THE HELLENIC VETERINARY MEDICAL SOCIETY

Aujeszky's disease (pseudorabies): an old threat in current pig industry?, part II : epidemiology, immunity, prevention and the current situation in Greece

KV PapageorgiouAR BurrielG FilioussisG ChristodoulopoulosHans NauwynckSK Kritas

A1 Journal Article in JOURNAL OF THE HELLENIC VETERINARY MEDICAL SOCIETY

Better molecular insights in the pathogenesis of PRRSV infections and immune response show the way for more efficient PRRSV vaccines

Hans NauwynckWander Van BreedamHanne Van GorpUladzimir KarniychukMarc GeldhofA CaoMieke VerbeeckMerijn Vanhee

Characterization of a circulating PRRSV strain by means of random PCR cloning and full genome sequencing

Joris Van DoorsselaereMarc GeldhofHans NauwynckPeter Delputte

A1 Journal Article in VIROLOGY JOURNAL

Characterization of antigenic regions in the porcine reproductive and respiratory syndrome virus by the use of peptide-specific serum antibodies

Merijn VanheeWander Van BreedamSarah CostersMarc GeldhofYtse NoppeHans Nauwynck

A1 Journal Article in VACCINE

Clinical pathological and virological outcome of an infection with the Belgian equine arteritis virus strain 08P178

Sabrina VairoAnnelies VandekerckhoveLennert SteukersSarah GlorieuxWim Van Den BroeckHans Nauwynck

Comparative analysis of replication characteristics of BoHV-1 subtypes in bovine respiratory and genital mucosa explants: a phylogenetic enlightenment

Lennert SteukersAnnelies VandekerckhoveWim Van Den BroeckSarah GlorieuxHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Comparison of the efficacy of inactivated PRRSV vaccine virus grown on MARC-145 or PK15SN-CD163 cells

Marc GeldhofIris DelrueJ Van DoorsselaereHans Nauwynck

Description of an unusually large outbreak of nervous system disorders caused by equine herpesvirus 1 (EHV1) in 2009 in Belgium

Annick GryspeerdtAnnelies VandekerckhoveJoris Van DoorsselaereGerlinde Van de WalleHans Nauwynck

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Disordini riproduttivi di origine virale nella scrofa

Efficacy of a farm-specific inactivated PRRSV vaccine in the field

Marc GeldhofEllen de JongAlfonso Lopez RodriguezJ Van DoorsselaereDominiek MaesHans Nauwynck

Elucidation of HSV-1 and HSV-2 mucosal behavior in a new human genital organ culture for a better understanding and control of genital herpes

Lennert SteukersSarah GlorieuxSteven WeyersAnnelies VandekerckhoveMARIJE VAN DE WATERMaria CornelissenWim Van Den BroeckMarleen TemmermanHans Nauwynck

Embryonic apoptosis after BTV-8 infection in bovine hatched in vitro produced blastocysts

Leen VandaeleWendy WesselinghK De ClercqI De LeeuwHerman FavoreelAnn Van SoomHans Nauwynck

Equine alphaherpesviruses (EHV-1 and EHV-4) differ in their efficiency to infect mononuclear cells during early steps of infection in nasal mucosal explants

Annelies VandekerckhoveSarah GlorieuxAnnick GryspeerdtLennert SteukersJoris Van DoorsselaereN OsterriederGerlinde Van de WalleHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Equine herpesvirus 1 and 4 differ in their efficiency to infect mononuclear cells during early steps of infection in nasal mucosal explants

Annelies VandekerckhoveSarah GlorieuxAnnick GryspeerdtLennert SteukersJ Van DoorsselaereN OsterriederGerlinde Van de WalleHans Nauwynck

Equine nasal mucosal explants, a valuable tool to study early events of the pathogenesis of equine herpesvirus infections

Annelies VandekerckhoveHans NauwynckGerlinde Van de WalleWim Van Den Broeck

Exceptional outcome of an infection with a PCV2B strain in mid-gestational porcine foetuses

Dipongkor SahaUladzimir KarniychukMarc GeldhofRichard DucatelleJan Van DoorsselaereHans Nauwynck

Expression of late viral proteins is hampered in infected nasal mucosal leukocytes but not in epithelial cells during early EHV-1 infection

Annelies VandekerckhoveAnnick GryspeerdtHossein Bannazadeh BaghiGerlinde Van de WalleHans Nauwynck

Fetal and maternal cells are not present in the porcine myometrium and fetal placentas, respectively, at the last stage of gestation

Uladzimir KarniychukWander Van BreedamClaire Rogel-GaillardNadine Van RoyHans Nauwynck

Genetic characterization of African swine fever viruses from a 2008 outbreak in Tanzania

G MisinzoJ MagamboJ MasambuMG YongoloJoris Van DoorsselaereHans Nauwynck

A1 Journal Article in TRANSBOUNDARY AND EMERGING DISEASES

Herpes Simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa

Sarah GlorieuxClaus BachertHerman FavoreelAnnelies VandekerckhoveLennert SteukersAnamaria RekeckiWim Van Den BroeckR ClaytonHans Nauwynck

Herpes simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa

Sarah GlorieuxClaus BachertHerman FavoreelAnnelies VandekerckhoveLennert SteukersAnamaria RekeckiWim Van Den BroeckJoline GoossensSiska CroubelsReginald F Clayton et al.

A1 Journal Article in PLOS ONE

Herpes: the difficult one

Identification of non-neutralizing and neutralizing antigenic regions in PRRSV by the use of peptide-specific serum and antibodies

Merijn VanheeWander Van BreedamSarah CostersMarc GeldhofYtse NoppeHans Nauwynck

Increased replication of porcine circovirus type 2 in porcine cell cultures by statins

Dipongkor SahaDavid LefebvreHans Nauwynck

Interaction of the porcine reproductive and respiratory syndrome virus with the macrophage-specific lectin sialoadhesin

Wander Van BreedamHans NauwynckPeter Delputte

Intriguing interplay between feline infectious peritonitis virus and its receptors during entry in primary feline monocytes

Evelien Van HammeLowiese DesmaretsHannah DewerchinHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Intriguing interplay between feline infectious peronitis virus and its receptors during entry in primary feline monocytes

Evelien Van HammeLowiese DesmaretsHannah DewerchinHans Nauwynck

Mapping of neutralizing epitopes in the capsid protein of porcine circovirus 2

Dipongkor SahaDavid LefebvreKaren OomsPeter DelputteJ Van DoorsselaereHans Nauwynck

Outcome of experimental porcine circovirus type 1 infections in mid-gestational porcine foetuses

Dipongkor SahaDavid LefebvreRichard DucatelleJan Van DoorsselaereHans Nauwynck

A1 Journal Article in BMC VETERINARY RESEARCH

Outcome of porcine circovirus type 1 (PCV1) infections in mid-gestational porcine foetuses

Dipongkor SahaDavid LefebvreUladzimir KarniychukMarc GeldhofRichard DucatelleJ Van DoorsselaereHans Nauwynck

PRRSV binding to and/or internalization by its receptor sialoadhesin on macrophages is sufficient to compromise phagocytosis

Miet De BaereHanne Van GorpPeter DelputteHans Nauwynck

PRRSV challenge of late term pregnant gilts vaccinated with an experimental inactivated vaccine

Uladzimir KarniychukMarc GeldhofMerijn VanheeDipongkor SahaHans Nauwynck

PRRSV efficiently replicates in fetal implantation sites and causes apoptosis in infected macrophages and surrounding cells

Uladzimir KarniychukDipongkor SahaMarc GeldhofMerijn VanheeHans Nauwynck

Porcine reproductive and respiratory syndrome virus (PRRSV) causes apoptosis during its replication in fetal implantation sites

Uladzimir KarniychukDipongkor SahaMarc GeldhofMerijn VanheePieter CornillieWim Van Den BroeckHans Nauwynck

A1 Journal Article in MICROBIAL PATHOGENESIS

Porcine reproductive and respiratory syndrome virus (PRRSV) entry in its host cell, the macrophage

Hans NauwynckHanne Van GorpMieke VerbeeckIlias FrydasWander Van Breedam

Porcine reproductive and respiratory syndrome virus (PRRSV)-specific mAbs: supporting diagnostics and providing new insights into the antigenic properties of the virus

Wander Van BreedamSarah CostersMerijn VanheeCarl A GagnonIrene M Rodriguez-GomezMarc GeldhofMieke VerbeeckJan Van DoorsselaereUladzimir KarniychukHans Nauwynck

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Porcine sialoadhesin (CD169/Siglec-1) is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages

Peter DelputteHanne Van GorpHerman FavoreelInge HoebekeIris DelrueHannah DewerchinFrederik VerdonckBruno VerhasseltEric CoxHans Nauwynck

A1 Journal Article in PLOS ONE

Quantification of regulatory T cells during infection with feline infectious peronitis virus

Ben VermeulenSabine GleichDominique OlyslaegersAnnelike DedeurwaerderLowiese DesmaretsHannah DewerchinHans Nauwynck

Research-driven development of new generation adaptable PRRSV vaccines

Hans NauwynckMarc GeldhofMerijn Vanhee

Role of group A p21-activated kinases in the anti-apoptotic activity of the pseudorabies virus US3 protein kinase

Celine Van den BroekeM RaduHans NauwynckJ ChernoffHerman Favoreel

A1 Journal Article in VIRUS RESEARCH

Sibling and fetal microchimerism in healthy and porcine reproductive and respiratory syndrome virus infected dams

Uladzimir KarniychukWander Van BreedamClaire Rogel-GaillardNadine Van RoyHans Nauwynck

Susceptibility of in vitro produced hatched bovine blastocysts to infection with bluetongue virus serotype 8

Leen VandaeleWendy WesselinghKris De ClercqIlse De LeeuwHerman FavoreelAnn Van SoomHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

The current status and future directions of myxoma virus, a master in immune evasion

Bart SpiesschaertGrant McFaddenKatleen HermansHans NauwynckGerlinde Van de Walle

A1 Journal Article in VETERINARY RESEARCH

The importance of cumilus expansion for monospermic fertilization of porcine cumulus-oocyte complexes

Josine BeekJo BijttebierDominiek MaesHans NauwynckAnn Van Soom

The pathogenesis of EHV1 in horses : novel insights from experimental inoculations and field situations

Annick GryspeerdtHans NauwynckGerlinde Van de Walle

Ultrasound prediction of the partus datum in dogs

PA de WispelaereAnn Van SoomTom RijsselaereJimmy SaundersG StormsDieter VerdonckEva VandermeulenC De SadeleerA DobbeleirHamphrey Ham et al.

A1 Journal Article in TIJDSCHRIFT VOOR DIERGENEESKUNDE

Use of a farm-specific inactivated vaccine for boosting the humoral immunity of infection-immune sows in comparison with the current available commercial vaccines

Marc GeldhofUladzimir KarniychukJ Van DoorsselaereTamara VandersmissenDominiek MaesHans Nauwynck

2010

A trypsin-like serine protease is involved in PRV invasion through the basement membrane barrier in porcine nasal respiratory mucosa

Sarah GlorieuxHerman FavoreelHans Nauwynck

A variable region in GP4 of European-type porcine reproductive and respiratory syndrome virus induces neutralizing antibodies against homologous but not heterologous virus strains

Merijn VanheeSarah CostersWander Van BreedamMarc GeldhofJan Van DoorsselaereHans Nauwynck

A1 Journal Article in VIRAL IMMUNOLOGY

Alphaherpesvirus use and misuse of cellular actin and cholesterol

Herman FavoreelCeline Van den BroekeAnn DesplanquesMatthias DeruelleG Van MinnebruggenHans NauwynckSarah GlorieuxNina Van OpdenboschNick De Regge

A1 Journal Article in VETERINARY MICROBIOLOGY

Canine herpes virus 1-infections in dogs : truth and lies

Cholesterol depletion affects infectivity and stability of pseudorabies virus

Ann DesplanquesMaria Setas Lopes PontesNatasha De CorteNele VerheyenHans NauwynckDries VercauterenHerman Favoreel

A1 Journal Article in VIRUS RESEARCH

Clinical and virological outcome of experimental PCV2a and PCV2b infections in mid-gestational porcine foetuses

Dipongkor SahaDavid LefebvreJoris Van DoorsselaereKalina AtanasovaFilip BarbéMarc GeldhofUladzimir KarniychukHans Nauwynck

Comparative analysis of replication characteristics of different BoHV-1 subtypes in bovine respiratory and genital mucosa explants

Lennert SteukersSarah GlorieuxAnnelies VandekerckhoveHans Nauwynck

Comparative analysis of replication characteristics of different BoHV-1 subtypes in bovine respiratory and genital mucosa explants: a phylogenetic enlightenment

Lennert SteukersSarah GlorieuxAnnelies VandekerckhoveHans Nauwynck

Correlation between qPCR and virus isolation for the quantification of porcine circovirus type 2 in tissue samples from naturally infected pigs

A CaijDavid LefebvreYves Van der StedeCora MiryHans Nauwynck

Detection of truncated circular DNA species in Escherichia coli with a PCV2-containing plasmid with a single PCV2 origin of replication

Jan Van DoorsselaereDavid LefebvreHans NauwynckPeter Delputte

A1 Journal Article in INTERVIROLOGY

Development of a new inactivated porcine reproductive and respiratory syndrome virus (PRRSV) vaccine

Iris DelrueHans NauwynckPeter Delputte

Differences in replication kinetics and cell tropism between neurovirulent and non-neurovirulent EHV1 strains during the acute phase of infection in horses

Annick GryspeerdtAnnelies VandekerckhoveBarbara GarréFilip BarbéGerlinde Van de WalleHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Efficacy of an experimental inactivated PRRSV vaccine based on a recently isolated field strain

Marc GeldhofMerijn VanheeJoris Van DoorsselaereHans Nauwynck

Efficacy of an experimental inactivated PRRSV vaccine based on a recently isolated field strain

Marc GeldhofMerijn VanheeJ Van DoorsselaereUladzimir KarniychukHans Nauwynck

Feline cell-mediated immune response against viral pathogens using 5-bromo-2’-deoxyuridine (BrdU) labeling

Ben VermeulenLeslie BosselerHannah DewerchinHans Nauwynck

GP4 of porcine reproductive and respiratory syndrome virus contains a neutralizing epitope that is susceptible to immunoselection in vitro

Sarah CostersDavid LefebvreJan Van DoorsselaereMerijn VanheePeter DelputteHans Nauwynck

A1 Journal Article in ARCHIVES OF VIROLOGY

GP4-specific neutralizing antibodies might be a driving force in PRRSV evolution

Sarah CostersMerijn VanheeWander Van BreedamJan Van DoorsselaereMarc GeldhofHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Genetic diversity of porcine reproductive and respiratory syndrome virus isolates in Flanders

Marc GeldhofJan Van DoorsselaereMerijn VanheeWander Van BreedamUladzimir KarniychukHans Nauwynck

Genetic diversity of porcine reproductive and respiratory syndrome virus isolates in Flanders

Marc GeldhofJan Van DoorsselaereMerijn VanheeWander Van BreedamUladzimir KarniychukHans Nauwynck

Going the whole hog

A4 Journal Article in INTERNATIONAL INNOVATION

Identification of the CD163 protein domains involved in infection of the porcine reproductive and respiratory syndrome virus

Hanne Van GorpWander Van BreedamJan Van DoorsselaerePeter DelputteHans Nauwynck

Identification of the CD163 protein domains involved in infection of the porcine reproductive and respiratory syndrome virus

Hanne Van GorpWander Van BreedamJan Van DoorsselaerePeter DelputteHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

Influence of sperm-oocyte coincubation period on porcine in vitro fertilization (IVF) efficiency

Josine BeekDominiek MaesHans NauwynckAnn Van Soom

Interferon alpha induces establishment of Alphaherpesvirus latency in sensory neurons in vitro

Nick De ReggeNina Van OpdenboschHans NauwynckStacey EfstathiouHerman Favoreel

A1 Journal Article in PLOS ONE

Is the zona pellucida an efficient barrier to viral infection?

Ann Van SoomAE WrathallA HerrlerHans Nauwynck

A1 Journal Article in REPRODUCTION FERTILITY AND DEVELOPMENT

Micro-dissecting the pathogenesis and immune response of PRRSV infection paves the way for more efficient PRRS vaccines

Hans NauwynckMerijn VanheeHanne Van GorpUladzimir KarniychukMarc GeldhofA CaoWander Van Breedam

Oral administration of beta-1,3/1,6-glucan Macrogard® fails to enhance the mucosal immune response following oral F4 fimbrial immunisation in gnotobiotic pigs

Edith StuyvenWim Van Den BroeckHans NauwynckBruno GoddeerisEric Cox

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

PCV2 impact on reproduction in swine

Hans NauwynckAnn Van SoomR SanchezP MeertsB MateusenG MisinzoDavid LefebvreDipongkor Saha

PRRSV efficiently replicates in fetal implantation sites and causes apoptosis in infected macrophages and surrounding cells

Uladzimir KarniychukDipongkor SahaMarc GeldhofMerijn VanheeHans Nauwynck

Pathogenesis and antigenic characterization of a new East European subtype 3 porcine reproductive and respiratory syndrome virus isolate

Uladzimir KarniychukMarc GeldhofMerijn VanheeJ Van DoorsselaereTA SavelevaHans Nauwynck

A1 Journal Article in BMC VETERINARY RESEARCH

Pathologic and virologic findings in mid-gestational porcine foetuses after experimental inoculation with PCV2a or PCV2b

Dipongkor SahaDavid LefebvreJan Van DoorsselaereKalina AtanasovaFilip BarbéMarc GeldhofUladzimir KarniychukHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Pathologic and virologic findings in mid-gestational porcine foetuses after experimental inoculation with PCV2a or PCV2b

Dipongkor SahaDavid LefebvreJ Van DoorsselaereKalina AtanasovaFilip BarbéMarc GeldhofUladzimir KarniychukHans Nauwynck

Porcine reproductive and respiratory syndrome virus (PPRSV) replication in fetal implantation sites

Uladzimir KarniychukDipongkor SahaMarc GeldhofMerijn VanheePieter CornillieHans Nauwynck

Porcine reproductive and respiratory syndrome virus (PRRSV) causes apoptosis during its replication in fetal implantation sites

Uladzimir KarniychukDipongkor SahaMarc GeldhofMerijn VanheePieter CornillieHans Nauwynck

Porcine reproductive and respiratory syndrome virus (PRRSV) entry in its host cell, the macrophage

Hans NauwynckWander Van Breedam

Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage

Wander Van BreedamPeter DelputteHanne Van GorpGerald MisinzoNathalie VanderheijdenXiaoBo DuanHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Pseudorabies virus US3-mediated inhibition of apoptosis does not affect infectious virus production

Matthias DeruelleNatasha De CorteJoan EnglebienneHans NauwynckHerman Favoreel

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Replication kinetics of neurovirulent versus non-neurovirulent equine herpesvirus type 1 strains in equine nasal mucosal explants

Annelies VandekerckhoveSarah GlorieuxAnnick GryspeerdtLennert SteukersLuc DuchateauN OsterriederGerlinde Van de WalleHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Replication of avian, human and swine influenza viruses in porcine respiratory explants and association with sialic acid distribution

Sjouke Van PouckeJohn M NichollsHans NauwynckKristien Van Reeth

A1 Journal Article in VIROLOGY JOURNAL

Role of p21-activated kinases 1 and 2 in pseudorabies virus US3-mediated effects on apoptosis and nuclear egress

Celine Van den BroekeC HoffmanHans NauwynckWim Van Den BroeckJ ChernoffHerman Favoreel

Role of p21-activated kinases 1 and 2 in pseudorabies virus US3-mediated effects on apoptosis and nuclear egress

Celine Van den BroekeC HoffmanHans NauwynckWim Van Den BroeckJ ChernoffHerman Favoreel

Role of the pseudorabies virus US3 protein kinase in the evasion of antiviral host responses during infection

Matthias DeruelleHerman FavoreelHans Nauwynck

Scavenger receptor CD163, a Jack-of-all-trades and potential target for cell-directed therapy

Hanne Van GorpPeter DelputteHans Nauwynck

A1 Journal Article in MOLECULAR IMMUNOLOGY

Sialoadhesin and CD163, a dynamic duo involved in porcine reproductive and respiratory syndrome virus entry in macrophages and possible targeting molecules

Hanne Van GorpHans NauwynckPeter Delputte

Susceptibility of bovine hatched blastocysts to bluetongue virus serotype 8 infection

Leen VandaeleWendy WesselinghKris De ClercqHans NauwynckAnn Van Soom

Susceptible cell lines for the production of porcine reproductive and respiratory syndrome virus by stable transfection of sialoadhesin and CD163

Iris DelrueHanne Van GorpJ Van DoorsselaerePeter DelputteHans Nauwynck

A1 Journal Article in BMC BIOTECHNOLOGY

The M/GP(5) glycoprotein complex of porcine reproductive and respiratory syndrome virus binds the sialoadhesin receptor in a sialic acid-dependent manner

Wander Van BreedamHanne Van GorpJiquan Q ZhangPaul R CrockerPeter DelputteHans Nauwynck

A1 Journal Article in PLOS PATHOGENS

2009

Absence of antibody-dependent, complement-mediated lysis of feline infectious peritonitis virus-infected cells

Els CornelissenHannah DewerchinEvelien Van HammeHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases

Celine Van den BroekeMaria RaduMatthias DeruelleHans NauwynckClemens HofmannZahara M JafferJonathan ChernoffHerman Favoreel

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An outbreak of sheep-associated malignant catarrhal fever in sows

B MateusenP VytStefaan RibbensS Van ColenC LetellierP KerkhofsHans NauwynckDominiek Maes

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Assessing the functionality of viral entry-associated domains of porcine reproductive and respiratory syndrome virus during inactivation procedures, a potential tool to optimize inactivated vaccines

Iris DelruePeter DelputteHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Determination of acyclovir in horse plasma and body fluids by high-performance liquid chromatography combined with fluorescence detection and heated electrospray ionization tandem mass spectrometry

An MaesBarbara GarréNoël DesmetK van der MeulenHans NauwynckPatrick De BackerSiska Croubels

A1 Journal Article in BIOMEDICAL CHROMATOGRAPHY

Development of an experimental inactivated PRRSV vaccine that induces virus-neutralizing antibodies

Merijn VanheePeter DelputteIris DelrueMarc GeldhofHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Different replication characteristics of historical pseudorabies virus strains in porcine respiratory nasal mucosa explants

Sarah GlorieuxHerman FavoreelGeert MeesenWinnok De VosWim Van Den BroeckHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Effect of dose and challenge routes of Vibrio spp. on co-infection with white spot syndrome virus in Penaeus vannamei

Phuoc Le HongMathias CorteelCong Thanh NguyenHans NauwynckMaurice PensaertVictoria Alday-SanzWim Van Den BroeckPatrick SorgeloosPeter Bossier

A1 Journal Article in AQUACULTURE

Effect of multiple- and single-day enrofloxacin medications against dual experimental infection with avian pneumovirus and Escherichia coli in turkeys

An GarmynAn MartelR FroymanHans NauwynckLuc DuchateauFreddy HaesebrouckFrank Pasmans

A1 Journal Article in POULTRY SCIENCE

Efficacy of four enrofloxacin treatment regimens against experimental infection in turkey poults with avian pneumovirus and Ornithobacterium rhinotracheale

An GarmynAn MartelRobrecht FroymanHans NauwynckLuc DuchateauFreddy HaesebrouckFrank Pasmans

A1 Journal Article in AVIAN PATHOLOGY

Entry of feline infectious peritonitis virus in blood monocytes

Evelien Van HammeHans NauwynckHannah Dewerchin

Evaluation of orally administered valacyclovir in experimentally EHV1-infected ponies

Barbara GarréAnnick GryspeerdtSiska CroubelsPatrick De BackerHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Evidence that an Arg-Gly-Asp (RGD) adhesion sequence plays a role in bovine fertilization

Mirjan ThysHans NauwynckDominiek MaesAnn Van Soom

Expression and putative function of fibronectin and its receptor (integrin alpha-5 beta-1) in male and female gametes during bovine fertilization in vitro

Mirjan ThysHans NauwynckDominiek MaesMaarten HoogewijsDries VercauterenTom RijsselaereHerman FavoreelAnn Van Soom

A1 Journal Article in REPRODUCTION

Functional impairment of PRRSV-specific peripheral CD3(+)CD8(high) cells

Sarah CostersDavid LefebvreBruno GoddeerisPeter DelputteHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Genetic, antigenic and pathogenetic features of porcine circovirus type 2 strains

David LefebvreHans Nauwynck

Head-to-head agglutination of frozen-thawed boar spermatozoa in modified Tris-buffered medium

Josine BeekJo BijttebierDominiek MaesHans NauwynckAnn Van Soom

Immune evasion of feline infectious peritonitis virus-infected monocytes

Els CornelissenHans Nauwynck

In vitro culture of equine respiratory mucosa explants

Annelies VandekerckhoveSarah GlorieuxWim Van Den BroeckAnnick GryspeerdtKaren van der MeulenHans Nauwynck

A1 Journal Article in VETERINARY JOURNAL

Invasion of pseudorabies virus in porcine nasal respiratory mucosa explants

Sarah GlorieuxHans NauwynckHerman Favoreel

Molt stage and cuticle damage influence white spot syndrome virus immersion infection in penaeid shrimp

Mathias CorteelJoão José Pereira Dantas Da Rocha LimaMathieu WilleVictoria Alday-SanzMaurice PensaertPatrick SorgeloosHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Multiple oral dosing of valacyclovir in horses and ponies

Barbara GarréKris BaertHans NauwynckPiet DeprezPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Neonatal foal death due to infection with equine arteritis virus in Belgium

Annick GryspeerdtKoen ChiersJan GovaereGriet VercauterenRichard DucatelleGerlinde Van de WalleHans Nauwynck

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

New insights and advances in bovine fertilization in vitro

Mirjan ThysAnn Van SoomHans Nauwynck

Pharmacokinetic and pharmacodynamic properties of orally administered valacyclovir in an equine herpesvirus type 1 infection experiment

Siska CroubelsBarbara GarréAnnick GryspeerdtHans NauwynckPatrick De Backer

Porcine circovirus 2 infection of epithelial cells is clathrin-, caveolae- and dynamin-independent, actin and Rho-GTPase-mediated, and enhanced by cholesterol depletion

Gerald MisinzoPeter DelputteDavid LefebvreHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Porcine ulcerative dermatitis syndrome in sows: a form of vesicular cutaneous lupus erythematosus?

Alfonso Lopez RodriguezKoen ChiersSebastiaan Van HoorebekeEdith StuyvenTom MeynsHans NauwynckM WelleDominiek Maes

A1 Journal Article in VETERINARY RECORD

Pseudorabies virus US3-and UL49.5-dependent and -independent downregulation of MHC I cell surface expression in different cell types

Matthias DeruelleCeline Van den BroekeHans NauwynckThomas C MettenleiterHerman Favoreel

A1 Journal Article in VIROLOGY

Quantitative changes of Sialoadhesin and CD163 positive macrophages in the implantation sites and organs of porcine embryos/fetuses during gestation

Uladzimir KarniychukHans Nauwynck

A1 Journal Article in PLACENTA

Recombination of two porcine circovirus type 2 strains

David LefebvreJ Van DoorsselaerePeter DelputteHans Nauwynck

A1 Journal Article in ARCHIVES OF VIROLOGY

Role of cholesterol and lipid rafts during pseudorabies virus infection

Ann DesplanquesHerman FavoreelHans Nauwynck

Serosurvey for viruses associated with reproductive failure in newly introduced gilts and in multiparous sows in Belgian sow herds

David LefebvreKristien Van ReethFrédéric VangroenwegheDominiek MaesE Van DriesscheM LaitatHans Nauwynck

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Simultaneous zoonotic transmission of Chlamydophila psittaci genotypes D, F and E/B to a veterinary scientist

Caroline Van DroogenbroeckDelphine Sylvie Anne BeeckmanKristel VerminnenMaja MariënHans NauwynckLeopold de Thibault de BoesingheDaisy Vanrompay

A1 Journal Article in VETERINARY MICROBIOLOGY

The effect of reduced treatment time and dosage of enrofloxacin on the course of respiratory disease caused by avian metapneumovirus and Ornithobacterium rhinotracheale

An GarmynAn MartelR FroymanC LudwigHans NauwynckFreddy HaesebrouckFrank Pasmans

A1 Journal Article in POULTRY SCIENCE

The kinase activity of pseudorabies virus US3 is required for modulation of the actin cytoskeleton

Celine Van den BroekeMatthias DeruelleHans NauwynckKelly E CollerGregory A SmithJan Van DoorsselaereHerman Favoreel

A1 Journal Article in VIROLOGY

The mechanism of pseudorabies virus US3-mediated actin rearrangements

Celine Van den BroekeHerman FavoreelHans Nauwynck

The porcine reproductive and respiratory syndrome virus requires trafficking through CD163-positive early endosomes, but not late endosomes, for productive infection

Hanne Van GorpWander Van BreedamPeter DelputteHans Nauwynck

A1 Journal Article in ARCHIVES OF VIROLOGY

The role of dendritic cells in alphaherpesvirus infections: archetypes and paradigms

Gerlinde Van de WalleEric CoxHans NauwynckHerman Favoreel

A1 Journal Article in REVIEWS IN MEDICAL VIROLOGY

2008

A review on the morphology, molecular characterization, morphogenesis and pathogenesis of white spot syndrome virus

CM ESCOBEDO-BONILLAV ALDAY-SANZMathieu WillePatrick SorgeloosMaurice PensaertHans Nauwynck

A1 Journal Article in JOURNAL OF FISH DISEASES

Antigenic differences among porcine circovirus type 2 strains, as demonstrated by the use of monoclonal antibodies

David LefebvreSarah CostersJ VAN DOORSSELAEREGerald MisinzoPL DEPUTTEHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Characterization of putative immune evasion mechanisms of feline infectious peritonitis virus

Hannah DewerchinHans NauwynckBruno VerhasseltHerman Favoreel

Clathrin- and caveolae-independent entry of feline infectious peritonitis virus in monocytes depends on dynamin

Evelien Van HammeHannah DewerchinEls CornelissenBruno VerhasseltHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Complexity of controlling foot-and-mouth disease

Nesya GorisHans Nauwynck

Diseases in swine transmitted by artificial insemination: An overview

Dominiek MaesHans NauwynckT RIJSSELAEREBart MateusenP VYTAart de KruifAnn Van Soom

A1 Journal Article in THERIOGENOLOGY

Effect of pre-incubation of male and female gametes with fibronectin prior to fertilization in vitro in cattle

Mirjan ThysHans NauwynckDominiek MaesAnn Van Soom

Expression and function of fibronectin in male and female gametes during bovine fertilization in vitro

Mirjan ThysHans NauwynckDominiek MaesHerman FavoreelAnn Van Soom

Foot-and-mouth disease vaccine potency testing in cattle using homologous and heterologous challenge strains: Precision of the "Protection against Podal Generalisation" test

Nesya GorisE MARADEIR D'ALOIAN FONDEVILAN MATTIONA PEREZE SMITSAARTHans NauwynckJ LA TORREE PALMA et al.

A1 Journal Article in VACCINE

Gene expression profiling of porcine alveolar macrophages after antibody-mediated cross-linking of sialoadhesin (Sn, Siglec-1)

S GENINIR MALINVERNIPeter DelputteS FIORENTINIA STELLAS BOTTIHans NauwynckE GIUFFRA

A1 Journal Article in JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Genome-wide transcriptional response of primary alveolar macrophages following infection with porcine reproductive and respiratory syndrome virus

S GENINIPeter DelputteR MALINVERNIM CECEREA STELLAHans NauwynckE GIUFFRA

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Increased porcine circovirus type 2 replication in porcine leukocytes in vitro and in vivo by concanavalin A stimulation

David LefebvrePeter MeertsSarah CostersGerald MisinzoFilip BarbéKristien Van ReethHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Increased susceptibility of white spot syndrome virus-infected Litopenaeus vannamei to Vibrio campbellii

LH PHUOCMathias CorteelHans NauwynckMaurice PensaertV ALDAY-SANZWim Van Den BroeckPatrick SorgeloosPeter Bossier

A1 Journal Article in ENVIRONMENTAL MICROBIOLOGY

Increased yield of porcine circovirus-2 by a combined treatment of PK-15 cells with interferon-gamma and inhibitors of endosomal-lysosomal system acidification

Gerald MisinzoPeter DelputteDavid LefebvreHans Nauwynck

A1 Journal Article in ARCHIVES OF VIROLOGY

Indirect foot-and-mouth disease vaccine potency testing based on a serological alternative

Nesya GorisT WILLEMSVI DIEVP MERKELBACH-PETERST VANBINSTY VAN DER STEDEHP KRAFTVM ZAKHAROVVV BORISOVHans Nauwynck et al.

A1 Journal Article in VACCINE

Inhibition of endosome-lysosome system acidification enhances porcine circovirus 2 infection of porcine epithelial cells

Gerald MisinzoPeter DelputteHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

Involvement of proteases in porcine reproductive and respiratory syndrome virus uncoating upon internalization in primary macrophages

Gerald MisinzoPeter DelputteHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

PCV-2 genotype definition and nomenclature

J SEGALESA OLVERAL GRAU-ROMAC CHARREYREHans NauwynckL LARSENK DUPONTK MCCULLOUGHJ ELLISS KRAKOWKA et al.

A1 Journal Article in VETERINARY RECORD

Pharmacokinetics and clinical efficacy of acyclovir in the treatment of equine herpes virus type 1 infections

Barbara GarréSiska CroubelsHans Nauwynck

Plasma membrane cholesterol is required for efficient pseudorabies virus entry

Ann DesplanquesHans NauwynckDries VercauterenTom GeensHerman Favoreel

A1 Journal Article in VIROLOGY

Porcine reproductive and respiratory syndrome virus modulates apoptosis during replication in alveolar macrophages

Sarah CostersDavid LefebvrePeter DelputteHans Nauwynck

A1 Journal Article in ARCHIVES OF VIROLOGY

Presence of Integrin Alpha5 in Bovine Gametes

Mirjan ThysHans NauwynckHerman FavoreelAnn Van Soom

Sialoadhesin and CD163 join forces during entry of the porcine reproductive and respiratory syndrome virus

Hanne Van GorpWander Van BreedamPeter DelputteHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Single and dual experimental infection of specific pathogen-free Litopenaeus vannamei shrimp with White Spot Syndrome Virus and Vibrio species

Hong Phuoc LePeter BossierHans Nauwynck

Strategies exhibited by PRRSV allowing evasion of immune detection and/or clearance in the infected pig

Sarah CostersHans NauwynckPeter Delputte

Surface-expressed viral proteins in feline infectious peritonitis virus-infected monocytes are internalized through a clathrin- and caveolae-independent pathway

Hannah DewerchinEls CornelissenEvelien Van HammeKaatje SmitsBruno VerhasseltHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Virulence of white spot syndrome virus (WSSV) isolates may be correlated with the degree of replication in gills of Penaeus vannamei juveniles

Muhammad RahmanMathias CorteelCM ESCOBEDO-BONILLAMathieu WilleV ALDAY-SANZMaurice PensaertPatrick SorgeloosHans Nauwynck

A1 Journal Article in DISEASES OF AQUATIC ORGANISMS

2007

A point mutation in the putative ATP binding site of the pseudorabies virus US3 protein kinase prevents Bad phosphorylation and cell survival following apoptosis induction

Matthias DeruelleKristin GeenenHans NauwynckHerman Favoreel

A1 Journal Article in VIRUS RESEARCH

AI transmitted diseases in swine: an overview

Dominiek MaesHans NauwynckTom RijsselaereBart MateusenPhilip VytAart de KruifAnn Van Soom

Absence of surface expression of feline infectious peritonitis virus (FIPV) antigens on infected cells isolated from cats with FIP

Els CornelissenHannah DewerchinEvelien Van HammeHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Attachment and internalization of feline infectious peritonitis virus in feline blood monocytes and Crandell feline kidney cells

Evelien Van HammeHannah DewerchinEls CornelissenHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Brn-3a suppresses pseudorabies virus-induced cell death in sensory neurons

K GEENENHans NauwynckNick De ReggeKevin BraeckmansHerman Favoreel

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Causes of abortion in sows

Dominiek MaesAnn Van SoomFreddy HaesebrouckHans NauwynckAart de Kruif

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Cell biological and molecular characteristics of pseudorabies virus infections in cell cultures and in pigs with emphasis on the respiratory tract

Hans NauwynckSarah GlorieuxHerman FavoreelMaurice Pensaert

A1 Journal Article in VETERINARY RESEARCH

Daily fluctuations of water temperature (27°C and 33°C) affect clinical and virological outcome of white spot syndrome virus (WSSV) infection in Penaeus vannamei juveniles

Muhammad RahmanMathias CorteelJoão José Pereira Dantas Da Rocha LimaMathieu WilleV ALDAY-SANZMaurice PensaertPatrick SorgeloosHans Nauwynck

Degree of replication in gills may be associated with virulence of white spot syndrome virus (WSSV) strains in infected Penaeus vannamei juveniles

Muhammad RahmanMathias CorteelMathieu WilleV ALDAY-SANZMaurice PensaertPatrick SorgeloosHans Nauwynck

Differences in virulence between white spot syndrome virus (WSSV) isolates and testing of some control strategies in WSSV infected shrimp

Meezanur RahmanHans NauwynckMaurice PensaertPatrick Sorgeloos

Effect of a porcine circovirus type 2 infection on embryos during early pregnancy

Bart MateusenDominick MaesAnn Van SoomDavid LefebvreHans Nauwynck

A1 Journal Article in THERIOGENOLOGY

Efficacy of enrofloxacin, florfenicol and amoxicillin against Ornithobacterium rhinotracheale and Escherichia coli O2: K1 dual infection in turkeys following APV priming

Maja MarienAnnemie DecostereLuc DuchateauKoen ChiersR FROYMANHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Efficacy of high water temperature (33°C) to prevent disease and reduce mortality in Penaeus vannamei juveniles infected with white spot syndrome virus depends on progression of infection

Muhammad RahmanMathias CorteelMathieu WilleV ALDAY-SANZMaurice PensaertPatrick SorgeloosHans Nauwynck

Embryotoxicity assay for antiviral compound BPIP (5-[(4-bromophenyl)methyl]-2-phenyl-5H-imidazo[4,5-c]pyridine) in bovine in vitro-produced embryos

Johanna MestachJ PAESHUYSEJ NEYTSHans NauwynckDominiek MaesAnn Van Soom

Enhancement of PCV2 infection and production by treatment of PK-15 cells with a combination of IFN-γ and inhibitors of endosomal-lysosomal system acidification

Gerald MisinzoHans Nauwynck

Expression of fibronectin on male and female gametes in bovine

Mirjan ThysS AZEVEDOHans NauwynckAnn Van Soom

Expression of vitronectin on male gamete in cattle

Mirjan ThysS AZEVEDOHans NauwynckAnn Van Soom

IFN-α treatment enhances porcine Arterivirus infection of monocytes via upregulation of the porcine Arterivirus receptor sialoadhesin

Peter DelputteWander Van BreedamFilip BarbéKristien Van ReethHans Nauwynck

A1 Journal Article in JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Impact of daily fluctuations of optimum (27 degrees C) and high water temperature (33 degrees C) on Penaeus vannamei juveniles infected with white spot syndrome virus (WSSV)

Meezanur RahmanMathias CorteelJJ DANTAS-LIMAMathieu WilleV ALDAY-SANZMaurice PensaertPatrick SorgeloosHans Nauwynck

A1 Journal Article in AQUACULTURE

In vitro culture of porcine respiratory nasal mucosa explants for studying the interaction of orcine viruses with the respiratory tract

Sarah GlorieuxWim Van Den BroeckKM VAN DER MEULENKristien Van ReethHerman FavoreelHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGICAL METHODS

In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet

Barbara GarréK VAN DER MEULENJ NUGENTJ NEYTSSiska CroubelsPatrick De BackerHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Inhibition of endosomal-lysosomal system acidification in porcine epithelial cells enhances porcine circovirus 2 infection

Gerald MisinzoHans Nauwynck

Interaction of viruses with porcine embryos

Bart MateusenAnn Van SoomDominiek MaesHans Nauwynck

Interferon alpha dependent enhancement of porcine reproductive and respiratory syndrome virus infection of monocytes

Peter DelputteWander Van BreedamMerijn VanheeFilip BarbéKristien Van ReethHans Nauwynck

Pathogenesis of a Thai strain of white spot syndrome virus (WSSV) in juvenile, specific pathogen-free Litopenaeus vannamei

CM ESCOBEDO-BONILLAMathieu WilleVA SANZPatrick SorgeloosMaurice PensaertHans Nauwynck

A1 Journal Article in DISEASES OF AQUATIC ORGANISMS

Pathogenesis of porcine circovirus 2 infections

Hans NauwynckDavid LefebvreGerald Misinzo

Pharmacokinetics of acyclovir after intravenous infusion of acyclovir and after oral administration of acyclovir and its prodrug valacyclovir in healthy adult horses

Barbara GarréKhaled ShebanyAnnick GryspeerdtKris BaertK VAN DER MEULENHans NauwynckPiet DeprezPatrick De BackerSiska Croubels

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Porcine arterivirus attachment to the macrophage-specific receptor sialoadhesin is dependent on the sialic acid-binding activity of the N-terminal immunoglobulin domain of sialoadhesin

Peter DelputteWander Van BreedamIris DelrueCornelia OetkePaul R CrockerHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

Porcine macrophage binding of human erythrocytes is mediated by sialoadhesin

L GODINGPeter DelputteHans NauwynckM REES

Quantitative determination of acyclovir in horse plasma and white blood cells using LC-ESI-MS/MS as part of a pharmacokinetic study

Barbara GarréNoël DesmetPatrick De BackerK Van der MeulenHans NauwynckSiska Croubels

Receptor mediated porcine arterivirus entry in macrophages

Peter DelputteHanne Van GorpWander Van BreedamGerald MisinzoIris DelrueHans Nauwynck

Receptor-determined resistance of preimplantation embryos to porcine reproductive and respiratory syndrome virus

Hans NauwynckBart MateusenDominiek MaesPeter DelputteAnn Van Soom

Receptor-determined susceptibility of porcine preimplantation embryos to pseudorabies virus

Hans NauwynckBart MateusenDominiek MaesHerman FavoreelAnn Van Soom

Receptor-determined susceptibility of preimplantation embryos to pseudorabies virus and porcine reproductive and respiratory syndrome virus

Bart MateusenAnn Van SoomDominiek MaesHerman FavoreelHans Nauwynck

A1 Journal Article in BIOLOGY OF REPRODUCTION

Replication of equine herpesvirus 1 in equine respiratory mucosa explants

Annelies VandekerckhoveWim Van Den BroeckKaren van der MeulenSarah GlorieuxAnnick GryspeerdtHans Nauwynck

Sialoadhesin (Siglec-1), a unique macrophage entry portal for targeted delivery of antigens and drugs

Sven ArnoutsHans NauwynckHanne Van GorpPeter Delputte

The effect of raising water temperature to 33 degrees C in Penaeus vannamei juveniles at different stages of infection with white spot syndrome virus (WSSV)

Muhammad RahmanMathias CorteelMathieu WilleVictoria Alday-SanzMaurice PensaertPatrick SorgeloosHans Nauwynck

A1 Journal Article in AQUACULTURE

The protective properties of vaccination against equine herpesvirus 1-induced viremia, abortion and nervous system disorders

Karen van der MeulenAnnick GryspeerdtAnnelies VandekerckhoveBarbara GarréHans Nauwynck

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Transmission of mice minute virus by in vivo -but not in vitro- produced mouse embryos

E MAHABIRD BULIANJ NEEDHAMR SCHMöLLERA MAYERBart MateusenAnn Van SoomHans NauwynckJessie Schmidt

Transmission of mice minute virus by in vivo-produced mouse embryos

E MAHABIR-BRENNERD BULIANJ NEEDHAMR SCHMOLLERA MAYERBart MateusenAnn Van SoomHans NauwynckJ SCHMIDT

Transmission of mouse minute virus (MMV) but not mouse hepatitis virus (MHV) following embryo transfer with experimentally exposed in vivo-derived embryos'

E MAHABIRD BULIANJ NEEDHAMA MAYERBart MateusenAnn Van SoomHans NauwynckJ SCHMIDT

A1 Journal Article in BIOLOGY OF REPRODUCTION

Tyrosine phosphorylation and lipid raft association of pseudorabies virus glycoprotein E during antibody-mediated capping

Ann DesplanquesHans NauwynckKelly TillemanDieter DeforceHerman Favoreel

A1 Journal Article in VIROLOGY

2006

A homologous in vitro model to study interactions between alphaherpesviruses and trigeminal ganglion neurons

Nick De ReggeHerman FavoreelKristin GeenenHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Absence of viral envelope proteins in equine herpesvirus 1-infected blood mononuclear cells during cell-associated viremia

Karen van der MeulenB CAIJMaurice PensaertHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Cell type-specific resistance of trigeminal ganglion neurons towards apoptotic stimuli

Kristin GeenenHerman FavoreelHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Clinical effect of cidofovir and a diet supplemented with Spirulina platensis in white spot syndrome virus (WSSV) infected specific pathogen-free Litopenaeus vannamei juveniles

Muhammad RahmanCM ESCOBEDO-BONILLAMathieu WilleVA SANZLieve AudoornJ NEYTSMaurice PensaertPatrick SorgeloosHans Nauwynck

A1 Journal Article in AQUACULTURE

Comparison of the efficacy of four antimicrobial treatment schemes against experimental Ornithobacterium rhinotracheale infection in turkey poults pre-infected with avian pneumovirus

Maja MarienHans NauwynckLuc DuchateauAn MartelKoen ChiersLuc DevrieseR FROYMANAnnemie Decostere

A1 Journal Article in AVIAN PATHOLOGY

Effect of high water temperature (33 degrees C) on the clinical and virological outcome of experimental infections with white spot syndrome virus (WSSV) in specific pathogen-free (SPF) Litopenaeus vannamei

Muhammad RahmanCM ESCOBEDO-BONILLAMathias CorteelJJ DANTAS-LIMAMathieu WilleVA SANZMaurice PensaertPatrick SorgeloosHans Nauwynck

A1 Journal Article in AQUACULTURE

Effect of high water temperature on the virological and clinical outcome of experimental infections with white spot syndrome virus (WSSV) in specific pathogen free (SPF) Litopenaeus vannamei. Aqua 2006, Joint International Conference & Exhibition of European Aquaculture Society & World Aquaculture Society. Florence, Italy

Muhammad RahmanMathias CorteelJoão José Pereira Dantas Da Rocha LimaMathieu WilleV ALDAY-SANZMaurice PensaertPatrick SorgeloosHans Nauwynck

Efficacy of an inactivated PRRSV vaccine - Induction of virus-neutralizing antibodies and partial virological protection upon challenge

Gerald MisinzoPeter DelputteP MEERTSC DREXLERHans Nauwynck

A1 Journal Article in NIDOVIRUSES: TOWARD CONTROL OF SARS AND OTHER NIDOVIRUS DISEASES

Equine coital exanthema in a mare in Belgium

Karen van der MeulenA CAIJK SMETSHans Nauwynck

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Evolutionary history of the closely related group 2 coronaviruses: Porcine hemagglutinating encephalomyelitis virus, bovine coronavirus, and human coronavirus OC43

L VIJGENE KEYAERTSP LEMEYP MAESKristien Van ReethHans NauwynckMaurice PensaertMarijke Van Ranst

A1 Journal Article in JOURNAL OF VIROLOGY

Feline infectious peritonitis virus-infected monocytes internalize viral membrane-bound proteins upon antibody addition

Hannah DewerchinEls CornelissenHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Herpesvirus interference with virus-specific antibodies: bridging antibodies, internalizing antibodies, and hiding from antibodies

Herman FavoreelGeert Van MinnebruggenGerlinde Van de WalleJolanta FicinskaHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Immune escape of equine herpesvirus 1 and other herpesviruses of veterinary importance

Karen van der MeulenHerman FavoreelMaurice PensaertHans Nauwynck

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

In vitro comparison of antiviral drugs against feline herpesvirus 1

K VAN DER MEULENBarbara GarréSiska CroubelsHans Nauwynck

In vitro comparison of antiviral drugs against feline herpesvirus 1

Karen van der MeulenBarbara GarréSiska CroubelsHans Nauwynck

A2 Journal Article in BMC VETERINARY RESEARCH

In vitro potency of selected antiviral compounds against six isolates of equine herpesvirus-1 and pharmacokinetics of acyclovir in horses

Barbara GarréK VAN DER MEULENPatrick De BackerHans NauwynckSiska Croubels

In vivo selection of reduced enrofloxacin susceptibility in Ornithobacterium rhinotracheale and its resistance-related mutations in gyrA

Maja MarienAnnemie DecostereHans NauwynckR FROYMANLuc DevrieseFreddy Haesebrouck

A1 Journal Article in MICROBIAL DRUG RESISTANCE-MECHANISMS EPIDEMIOLOGY AND DISEASE

Lefebvre D.J., Meerts P., Misinzo G., Nielsen J., Bøtner A., Kristensen C.S. and Nauwynck H.J. Absence of PCV2-neutralizing antibodies in PMWS-affected pigs. Proceedings of the 19th International Pig Veterinary Society Congress, Copenhagen, Denmark, 175

David LefebvrePeter MeertsGerald MisinzoHans Nauwynck

Long-term administration of a commercial porcine reproductive and respiratory syndrome virus (PRRSV)-inactivated vaccine in PRRSV-endemically infected sows

VG PAPATSIROSC ALEXOPOULOSSK KRITASG KOPTOPOULOSHans NauwynckMaurice PensaertKonstantinos Kyriakis

A1 Journal Article in JOURNAL OF VETERINARY MEDICINE SERIES B-INFECTIOUS DISEASES AND VETERINARY PUBLIC HEALTH

Mateusen B., Van Soom A., Maes D.G.D. and Nauwynck H.J. Susceptibility of embryonic cells of morulae and blastocysts to porcine parvovirus (PPV), pseudorabies virus (PRV) and porcine reproductive and respiratory syndrome virus (PRRSV). Proceedings of the 19th International Pig Veterinary Society Congress, Copenhagen, Denmark, 113

Bart MateusenAnn Van SoomDominiek MaesHans Nauwynck

Pathogenic interactions between Chlamydophila psittaci and avian pneurnovirus infections in turkeys

A VAN LOOCKK LOOTSSaskia Van De ZandeM VAN HEERDENHans NauwynckBruno GoddeerisDaisy Vanrompay

A1 Journal Article in VETERINARY MICROBIOLOGY

Plaquewise spread of pseudorabies virus in explants of porcine nasal respiratory mucosa

Sarah GlorieuxWim Van Den BroeckHerman FavoreelK VAN DER MEULENHans Nauwynck

Porcine arterivirus entry in macrophages - Heparan sulfate-mediated attachment, sialoadhesin-mediated internalization, and a cell-specific factor mediating virus disassembly and genome release

PL DEPUTTEHans Nauwynck

A1 Journal Article in NIDOVIRUSES: TOWARD CONTROL OF SARS AND OTHER NIDOVIRUS DISEASES

Porcine circovirus 2 uses heparan sulfate and chondroitin sulfate B glycosaminoglycans as receptors for its attachment to host cells

Gerald MisinzoPeter DelputtePeter MeertsDavid LefebvreHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

Porcine reproductive and respiratory syndrome virus (PRRSV) entry in macrophages. Proceedings of the 19th International Pig Veterinary Society Congress, Copenhagen, Denmark, 17

Peter DelputteGerald MisinzoHans Nauwynck

Porcine reproductive and respiratory syndrome virus-infected alveolar macrophages contain no detectable levels of viral proteins in their plasma membrane and are protected against antibody-dependent, complement-mediated cell lysis

Sarah CostersPeter DelputteHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Protection of PRRSV-infected macrophages against antibody-dependent, complement-mediated cell lysis due to absence of surface expression of viral proteins. Proceedings of the 19th International Pig Veterinary Society Congress, Copenhagen, Denmark

Sarah CostersPeter DelputteHans Nauwynck

Rahman M.M., Escobedo-Bonilla C.M., Corteel M., Wille M., Alday-Sanz V., Pensaert M.B., Sorgeloos P. and Nauwynck H.J. Evaluation of virulence of three white spot shrimp Litopenaeus vannamei. Aqua 2006, Joint International Conference & Exhibition of European Aquaculture Society & World Aquaculture Society. Florence, Italy

Muhammad RahmanMathias CorteelMathieu WilleV ALDAY-SANZMaurice PensaertPatrick SorgeloosHans Nauwynck

Serological profile at farm level after long-term vaccination of the breeding stock with a PRRSV incativated vaccine. Proceedings of the 19th International Pig Veterinary Society Congress, Copenhagen, Denmark

V PAPATSIROSC ALEXOPOULOSS KRITASG KOPTOPOULOSHans NauwynckMaurice PensaertKonstantinos Kyriakis

Special issue - Proceedings of the 2nd ESVV Veterinary Herpesvirus Symposium - Ghent, Belgium - 2nd-4th March, 2005 - Foreword

Herman FavoreelHans Nauwynck

Editorial material

Standardized white spot syndrome virus (WSSV) inoculation procedures for intramuscular or oral routes

CM ESCOBEDO-BONILLALieve AudoornMathieu WilleV ALDAY-SANZPatrick SorgeloosMaurice PensaertHans Nauwynck

A1 Journal Article in DISEASES OF AQUATIC ORGANISMS

alpha-herpesvirus glycoprotein D interaction with sensory neurons triggers formation of varicosities that serve as virus exit sites

Nick De ReggeHans NauwynckKristin GeenenC KRUMMENACHERGH COHENRJ EISENBERGTC METTENLEITERHerman Favoreel

A1 Journal Article in JOURNAL OF CELL BIOLOGY

2005

Analysis of porcine reproductive and respiratory syndrome virus attachment and internalization: distinctive roles for heparan sulphate and sialoadhesin

Peter DelputteSarah CostersHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Antivirale behandeling van rinotracheitisvirus, immunodeficientievirus en leukemievirus infecties bij de kat

Eva NeirinckxBarbara GarréHans NauwynckSiska CroubelsPatrick De BackerKaren van der Meulen

A3 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Assessement of the susceptibility of porcine preimplantation embryos to pseudorabies virus (PRV) and porcine reproductive and respiratory syndrome virus (PRRSV) using perivitelline microinjection

Bart MateusenAnn Van SoomDominiek MaesHans Nauwynck

Binding and entry characteristics of porcine circovirus 2 in cells of the porcine monocyte line 3D4/31

Gerald MisinzoPeter MeertsH WEINGARTLM BUBLOTJ MASTHans Nauwynck

Binding and entry characteristics of porcine circovirus 2 in cells of the porcine monocytic line 3D4/31

Gerald MisinzoPeter MeertsM BUBLOTJ MASTHM WEINGARTHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Correlation between differences in the immune response against porcine circovirus 2 and evolution in replcation in pigs

Peter MeertsDavid LefebvreEric CoxHans Nauwynck

Correlation between differences in the immune response against porcine circovirus 2 and evolution in replication in pigs

David LefebvreEric CoxHans Nauwynck

Correlation between type of adaptive immune response against porcine circovirus type 2 and level of virus replication

Peter MeertsSteven Van GuchtEric CoxA VANDEBOSCHHans Nauwynck

A1 Journal Article in VIRAL IMMUNOLOGY

Cytoskeletal rearrangements and cell extensions induced by the US3 kinase of an alphaherpesvirus are associated with enhanced spread

Herman FavoreelG VAN MINNEBRUGGEND ADRIAENSENHans Nauwynck

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficacy of Baytril® and other antimicrobial products in ORT or ORT/E. coli challenged turkeys using a recently developed challenge model

Maja MarienAnnemie DecostereHans Nauwynck

Enhancement of porcine circovirus 2 replication in porcine cell lines by IFN-γ before and after treatment and by IFN-α after treatment

Peter MeertsGerald MisinzoHans Nauwynck

A1 Journal Article in JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Equine herpesvirus-1 as a target for antiviral chemotherapy

Barbara GarréKaren van der MeulenSiska CroubelsPatrick De BackerHans Nauwynck

Heparan and dermatan sulphate glycosaminoglycans mediate porcine circovirus attachment to the porcine monocytic line 3D4/31

Peter MeertsGerald MisinzoHans Nauwynck

Higher resistance of porcine trigeminal ganglion neurons towards pseudorabies virus-induced cell death compared with other porcine cell types in vitro

Kristin GeenenHerman FavoreelHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

In vivo titration of white spot syndrome virus

V Alday-SanzCésar Escobedo BonillaMaurice PensaertHans NauwynckMathieu WillePatrick Sorgeloos

In vivo titration of white spot syndrome virus (WSSV) in specific pathogen-free Litopenaeus vannamei by intramuscular and oral routes

CM ESCOBEDO-BONILLAM WILLEVA SANZPatrick SorgeloosMB PENSAERTHans Nauwynck

A1 Journal Article in DISEASES OF AQUATIC ORGANISMS

Inhibition of bovine sperm-zona binding by bovine herpesvirus-1

Sofie TangheGeert VanrooseAnn Van SoomLuc DuchateauMT YsebaertP KerkhofsE ThirySV Littel-van den HurkPatric Van OostveldtHans Nauwynck

A1 Journal Article in REPRODUCTION

Interferon-gamma enhances porcine circovirus 2 infection in vitro

Peter MeertsGerald MisinzoHans Nauwynck

Key role of Chlamydophila psittaci on Belgian turkey farms in association with other respiratory pathogens

M VAN LOOCKTom GeensL DE SMITHans NauwynckP VAN EMPELC NAYLORHM HAFEZBruno GoddeerisDaisy Vanrompay

A1 Journal Article in VETERINARY MICROBIOLOGY

Pathogenesis of a Thai strain of white spot syndrome virus (WSSV) in specific-free Litopenaeus vannamei

Mathieu WilleV ALDAY-SANZPatrick SorgeloosMaurice PensaertHans Nauwynck

Porcine reproductive and respiratory syndrome virus infection increases CD14 expression and lipopolysaccharide-binding protein in the lungs of pigs

Steven Van GuchtKristien Van ReethHans NauwynckM PENSAERT

A1 Journal Article in VIRAL IMMUNOLOGY

Pseudorabies virus glycoprotein gD contains a functional endocytosis motif that acts in concert with an endocytosis motif in gB to drive internalization of antibody-antigen complexes from the surface of infected monocytes

J FICINSKAG VAN MINNEBRUGGENHans NauwynckK BIENKOWSKA-SZEWCZYKHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

Replication kinetics of different porcine circovirus 2 strains in PK-15 cells, fetal cardiomyocytes and macrophages

Peter MeertsGerald MisinzoF MCNEILLYHans Nauwynck

A1 Journal Article in ARCHIVES OF VIROLOGY

Replication of feline coronaviruses in peripheral blood monocytes

Hannah DewerchinEls CornelissenHans Nauwynck

A1 Journal Article in ARCHIVES OF VIROLOGY

Sialoadhesin: a macrophage receptor involved in binding sialic acid-bearing xenogeneic cells and viruses

L GODINGPeter DelputteHans NauwynckM REES

Sperm-oocyte interactions during bovine fertilization in vitro

Sofie TangheAnn Van SoomHans Nauwynck

Synergy between avian pneumovirus and Ornithobacterium rhinotracheale in turkeys

Maja MarienAnnemie DecostereAn MartelKoen ChiersR FROYMANHans Nauwynck

Synergy between avian pneumovirus and Ornithobacterium rhinotracheale in turkeys

Maja MarienAnnemie DecostereAn MartelKoen ChiersR FROYMANHans Nauwynck

A1 Journal Article in AVIAN PATHOLOGY

The complex interaction between porcine circovirus type 2 and the pig’s immune system

Peter MeertsHans Nauwynck

The pseudorabies virus US3 protein kinase possesses anti-apoptotic activity that protects cells from apoptosis during infection and after treatment with sorbitol or staurosporine

Kristin GeenenHerman FavoreelLeighAnne OlsenLynn W EnquistHans Nauwynck

A1 Journal Article in VIROLOGY

West Nile virus in the vertebrate world

Karen van der MeulenMB PENSAERTHans Nauwynck

A1 Journal Article in ARCHIVES OF VIROLOGY

2004

Aujeszky's disease vaccination and differentiation of vaccinated from infected pigs

M PENSAERTGeoffrey LabarqueHerman FavoreelHans Nauwynck

A2 Journal Article in Developmental biology Basel

Aujeszky's disease vaccination and differentiation of vaccinated from infected pigs

Maurice PensaertGeoffrey LabarqueHerman FavoreelHans Nauwynck

Aujeszky’s disease vaccination and differentiation of vaccinated from infected pigs

Maurice PensaertHerman FavoreelHans Nauwynck

Carbohydrates and glycoproteins involved in bovine fertilization in vitro

Sofie TangheAnn Van SoomLuc DuchateauHans NauwynckAart de Kruif

Carbohydrates and glycoproteins involved in bovine fertilization in vitro

Sofie TangheAnn Van SoomLuc DuchateauHans NauwynckAart de Kruif

A1 Journal Article in MOLECULAR REPRODUCTION AND DEVELOPMENT

Characteristics of porcine circovirus-2 replication in lymphoid organs of pigs inoculated in late gestation or postnatally and possible relation to clinical and pathological outcome of infection

RE SANCHEZPeter MeertsHans NauwynckJA ELLISMaurice Pensaert

A1 Journal Article in JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION

Comparison of the effects of temperature, spirulina and cidofovir on disease and mortality caused by WSSV infection

C ESCOBEDO-BONILLAMuhammad RahmanMathieu WilleV ALDAY-SANZPatrick SorgeloosMaurice PensaertHans Nauwynck

Copatching and lipid raft association of different viral glycoproteins expressed on the surfaces of pseudorabies virus-infected cells

Herman FavoreelTC METTENLEITERHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

Effect of virus-specific antibodies on attachment, internalization and infection of porcine reproductive and respiratory syndrome virus in primary macrophages

PL DEPUTTEPeter MeertsSarah CostersHans Nauwynck

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Impact of genetic diversity of European-type porcine reproductive and respiratory syndrome virus strains on vaccine efficacy

Geoffrey LabarqueSteven Van GuchtKristien Van ReethC DREXLERHans NauwynckMaurice Pensaert

Impact of genetic diversity of European-type porcine reproductive and respiratory syndrome virus strains on vaccine efficacy

Geoffrey LabarqueKristien Van ReethHans NauwynckC DREXLERSteven Van GuchtMaurice Pensaert

A1 Journal Article in VACCINE

In vitro susceptibility of morula and blastocyst stage embryos to pseudorabies virus (PRV) and porcine reproductive and respiratory syndrome virus (PRRSV)

Bart MateusenAnn Van SoomDominiek MaesHans Nauwynck

Internalization of pseudorabies virus glycoprotein B is mediated by an interaction between the YQRL motif in its cytoplasmic domain and the clathrin-associated AP-2 adaptor complex

Geert Van MinnebruggenHerman FavoreelHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

PMWS: experimental model and co-infections

GM ALLANF MCNEILLYJ ELLISS KRAKOWKAA BOTNERK MCCULLOUGHHans NauwynckS KENNEDYB MEEHANC CHARREYRE

A1 Journal Article in VETERINARY MICROBIOLOGY

Porcine Arterivirus infection of alveolar macrophages is mediated by sialic acid on the virus

PL DEPUTTEHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

Prevalence of porcine circovirus 2 (PCV2)-related wasting on Belgian farms with or without a history of postweaning multisystemic wasting syndrome

Peter MeertsHans NauwynckRE SANCHEZBart MateusenMaurice Pensaert

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Pseudorabies virus interactions with the cellular endocytosis machinery and actin cytoskeleton, and possible implications for antibody-resistant virus spread

Geert Van MinnebruggenHerman FavoreelHans Nauwynck

Replication of porcine circovirus 2 (PCV2) in PK-15 and porcine alveolar macrophages and diffences between PCV2-strains

Peter MeertsHans Nauwynck

Reproducible WSSV inoculation models by intramuscular or oral routes

C ESCOBEDO-BONILLAMathieu WilleV ALDAY-SANZPatrick SorgeloosMaurice PensaertHans Nauwynck

Susceptibility of pig embryos to porcine circovirus type 2 infection

Bart MateusenRE SANCHEZAnn Van SoomPeter MeertsDominiek MaesHans Nauwynck

A1 Journal Article in THERIOGENOLOGY

Susceptibility of porcine morulae and blastocyst stage embryos to pseudorabies virus and porcine reproductive and respiratory syndrome virus

Bart MateusenAnn Van SoomDominiek MaesHans Nauwynck

The vaginal microflora and canine herpesvirus 1 antibody titers throughout the estrous cycle of breeding bitches

Bianca FeyenAnn Van SoomHans NauwynckLuc DevrieseAnnemie DecostereBoudewijn CatryJeroen DewulfAart de Kruif

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Viremia and effect of fetal infection with porcine viruses with special reference to porcine circovirus 2 infection

Maurice PensaertRE SANCHEZAS LADEKJAER-MIKKELSENGM ALLANHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Viruses and assisted reproductive technology

Ann Van SoomM MATEUSENSofie TangheHans NauwynckAart de Kruif

2003

A local epidemic of equine herpesvirus 1-induced neurological disorders in Belgium

Karen van der MeulenGriet VercauterenHans NauwynckMaurice Pensaert

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Absence of viral antigens on the surface of equine herpesvirus-1-infected peripheral blood mononuclear cells: a strategy to avoid complement-mediated lysis

Karen van der MeulenHans NauwynckMaurice Pensaert

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Anti body-induced internalization of viral glycoproteins and gE-gl Fc receptor activity protect pseudorabies virus-infected monocytes from efficient complement-mediated lysis

Gerlinde Van de WalleHerman FavoreelHans NauwynckMaurice Pensaert

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Apoptosis in the lungs of pigs infected with porcine reproductive and respiratory syndrome virus and associations with the production of apoptogenic cytokines

Geoffrey LabarqueSteven Van GuchtHans NauwynckKristien Van ReethMaurice Pensaert

A1 Journal Article in VETERINARY RESEARCH

Change of porcine circovirus 2 target cells in pigs during development from fetal to early postnatal life

RE SANCHEZPeter MeertsHans NauwynckMaurice Pensaert

A1 Journal Article in VETERINARY MICROBIOLOGY

Entry process of porcine reproductive and respiratory syndrome virus in porcine alveolar macrophages

Hans NauwynckN VANDERHEIJDENPeter DelputteMaurice Pensaert

In vivo titration of white spot syndrome virus (WSSV) in shrimps

C ESCOBEDO-BONILLAHans NauwynckMathieu WillePatrick SorgeloosMaurice Pensaert

Interactions between PCV2 and porcine embryos

Bart MateusenAnn Van SoomDominiek MaesHans Nauwynck

Involvement of sialoadhesin in entry of porcine reproductive and respiratory syndrome virus into porcine alveolar macrophages

Nathalie VanderheijdenPeter DelputteHerman FavoreelJoël VandekerckhoveJozef Van DammePA VAN WOENSELHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

New insights in the pathogenesis of PCV2 infections in fetuses

Hans NauwynckR SANCHEZPeter MeertsBart MateusenMaurice Pensaert

PCV2 replication in lymph nodes of pigs inoculated in late-gestation or postnatally: virus quantification, immunophenotyping of target cells and relation to clinical and pathological outcome of infection

R SANCHEZPeter MeertsHans NauwynckJ ELLISMaurice Pensaert

PRRSV infection increases CD14 expression and LPS-binding protein in the lungs: possible mechanism of PRRSV-LPS clinical synergy

Steven Van GuchtKristien Van ReethGeoffrey LabarqueHans NauwynckMaurice Pensaert

Pathogenesis of porcine circovirus 2 infections in pigs from foetal to early postnatal life

Romeo SanchezHans NauwynckMaurice Pensaert

Pathogenic interaction of Chlamydophila psittaci, avian pneumovirus, Ornithobacterium rhinotracheale and Mycoplasma gallisepticum

M VAN LOOCKDaisy VanrompayHans NauwynckP VAN EMPELC NAYLORL DE SMITG VOLCKAERTBruno Goddeeris

Porcine reproductive and respiratory syndrome virus (PRRSV) distribution in lymphoid tissues is dependent of the resident macrophage population and the local T cel response

Z XIAOL BATISTAS DEEK ROSSOWHans NauwynckM MURTAUGH

Prevalence of PMWS in suspected and non-suspected Belgian farms

Peter MeertsR SANCHEZBart MateusenHans NauwynckMaurice Pensaert

Pseudorabies virus (PRV)-specific antibodies suppress intracellular viral protein levels in PRV-infected monocytes

Herman FavoreelGerlinde Van de WalleHans NauwynckThomas C MettenleiterMaurice Pensaert

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Pseudorabies virus US3 protein kinase mediates actin stress fiber breakdown

Geert Van MinnebruggenHerman FavoreelL JACOBSHans Nauwynck

A1 Journal Article in JOURNAL OF VIROLOGY

Respiratory tract protection upon challenge of pigs vaccinated with attenuated porcine reproductive and respiratory syndrome virus vaccines

Geoffrey LabarqueSteven Van GuchtKristien Van ReethHans NauwynckMaurice Pensaert

A1 Journal Article in VETERINARY MICROBIOLOGY

Susceptibility of pig embryos to porcine circovirus type 2 infection

Bart MateusenR SANCHEZAnn Van SoomP MEERTSDominiek MaesHans Nauwynck

Transmission of pseudorabies virus from immune-masked blood monocytes to endothelial cells

Gerlinde Van de WalleHerman FavoreelHans NauwynckThomas C MettenleiterMaurice Pensaert

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Virus complement evasion strategies

Herman FavoreelGerlinde Van de WalleHans NauwynckMaurice Pensaert

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

2002

A tyrosine-based motif in the cytoplasmic tail of pseudorabies virus glycoprotein B is important for both antibody-induced internalization of viral glycoproteins and efficient cell-to-cell spread.

Herman FavoreelGeert Van MinnebruggenHans NauwynckLW ENQUISTMaurice Pensaert

A1 Journal Article in JOURNAL OF VIROLOGY

Antibody-induced internalization of viral glycoproteins in pseudorabies virus-infected monocytes and role of the cytoskeleton: a confocal study

Gerlinde Van de WalleHerman FavoreelHans NauwynckPatric Van OostveldtMaurice Pensaert

A1 Journal Article in VETERINARY MICROBIOLOGY

Clinical and virological outcome of PCV2 infections in late-term fetuses and newborn piglets

R SANCHEZPeter MeertsHans NauwynckG ALLANMaurice Pensaert

Effect of a cytokine inhibitor on PRRS virus-bacterial endotoxin induced respiratory disease in pigs

Steven Van GuchtKristien Van ReethHans NauwynckMaurice Pensaert

Efficacy of avian pneumovirus vaccines against an avian pneumovirus/Escherichia coli O2: K1 dual infection in turkeys.

Saskia Van De ZandeHans NauwynckMaurice Pensaert

A1 Journal Article in VETERINARY RECORD

Efficacy testing of a modified live PRRSV vaccine using the clinical synergy between PRRS virus and bacterial lipopolysaccharides

Geoffrey LabarqueT MAGYARF KOVACSKristien Van ReethHans NauwynckMaurice Pensaert

Increased susceptibility of peripheral blood mononuclear cells to equine herpes virus type 1 infection upon mitogen stimulation: a role of the cell cycle and of cell-to-cell transmission of the virus.

Karen van der MeulenHans NauwynckMaurice Pensaert

A1 Journal Article in VETERINARY MICROBIOLOGY

Involvement of the matrix protein in attachment of porcine reproductive and respiratory syndrome virus to a heparinlike receptor on porcine alveolar macrophages.

Peter DelputteNathalie VanderheijdenHans NauwynckMaurice Pensaert

A1 Journal Article in JOURNAL OF VIROLOGY

Minireview: Functions of the cumulus oophorus during oocyte maturation, ovulation, and fertilization.

Sofie TangheAnn Van SoomHans NauwynckMarc CorynAart de Kruif

A1 Journal Article in MOLECULAR REPRODUCTION AND DEVELOPMENT

Pathogenicity of an avian pneumovirus infection in Chlamydophila psittaci infected turkeys

M VAN LOOCKDaisy VanrompaySaskia Van De ZandeHans NauwynckG VOLCKAERTBruno Goddeeris

Porcine reproductive-respiratory syndrome virus infection predisposes pigs for respiratory signs upon exposure to bacterial lipopolysaccharide.

Geoffrey LabarqueKristien Van ReethSteven Van GuchtHans NauwynckMaurice Pensaert

A1 Journal Article in VETERINARY MICROBIOLOGY

Reproduction failure induced by porcine circovirus 2-infections in sows

Hans NauwynckR SANCHEZPeter MeertsBart MateusenMaurice Pensaert

Seroprevalence of canine herpesvirus-1 in the Belgian dog population in 2000.

V RONSSEJ VERSTEGENK ONCLINAL GUIOTC AEBERLEHans NauwynckH POULET

A1 Journal Article in REPRODUCTION IN DOMESTIC ANIMALS

Seroprevalence of porcine reproductive and respiratory syndrome virus (PRRSV) in 20 Belgian farrow-to-finish pig herds

Bart MateusenDominiek MaesHans NauwynckB BALISM VERDONCKAart de Kruif

Synergy between PRRS virus and bacterial lipopolysaccharides in the induction of respiratory signs in pigs

Geoffrey LabarqueKristien Van ReethSteven Van GuchtHans NauwynckMaurice Pensaert

Temporary disturbance of actin stress fibers in swine kidney cells during pseudorabies virus infection

Geert Van MinnebruggenGerlinde Van de WalleHerman FavoreelHans NauwynckMaurice Pensaert

A1 Journal Article in VETERINARY MICROBIOLOGY

2001

Apoptosis in the lungs of pigs during an infection with a European strain of porcine reproductive and respiratory syndrome virus.

Geoffrey LabarqueHans NauwynckKristien Van ReethMaurice Pensaert

A1 Journal Article in NIDOVIRUSES (CORONAVIRUSES AND ARTERIVIRUSES)

Caniene herpesvirus infecties.

Steven Van GuchtHans NauwynckMaurice Pensaert

A3 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Clinical effects of experimental dual infections with porcine reproductive and respiratory syndrome virus followed by swine influenza virus in conventional and colostrum-deprived pigs.

Kristien Van ReethHans NauwynckMaurice Pensaert

A1 Journal Article in JOURNAL OF VETERINARY MEDICINE SERIES B-INFECTIOUS DISEASES AND VETERINARY PUBLIC HEALTH

Effects of heparin on the entry of porcine reproductive and respiratory syndrome virus into alveolar macrophages

Nathalie VanderheijdenPeter DelputteHans NauwynckMaurice Pensaert

A1 Journal Article in ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY

Field and experimental infections with turkey herpesvirus

Saskia Van De ZandeHans NauwynckMaurice Pensaert

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Influence of changes in the population of target cells and appearance of specific antibodies on the replication of porcine reproductive and respiratory syndrome virus in the lungs of pigs.

Hans NauwynckGeoffrey LabarqueKristien Van ReethMaurice Pensaert

A1 Journal Article in NIDOVIRUSES (CORONAVIRUSES AND ARTERIVIRUSES)

Involvement of cellular cytoskeleton components in antibody-induced internalization of viral glycoproteins in pseudorabies virus-infected monocytes

Gerlinde Van de WalleHerman FavoreelHans NauwynckPatric Van OostveldtMaurice Pensaert

A1 Journal Article in VIROLOGY

Mitogen stimulation favours replication of equine herpesvirus-1 in equine blood mononuclear cells by inducing cell proliferation and formation of close intercellular contacts.

Karen van der MeulenHans NauwynckMaurice Pensaert

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

No effect of turkey herpesvirus infections on the outcome of avian pneumovirus infections in turkeys.

Saskia Van De ZandeHans NauwynckMaurice Pensaert

A1 Journal Article in AVIAN DISEASES

PMWS: experimental model and co-infections.

GM ALLANF MCNEILLYJ ELLISS KRAKOWKAA BOTNERK MCCULLOUGHHans NauwynckS KENNEDYB MEEHANC CHARREYRE

Porcine circovirus 2 infection in swine foetuses inoculated at different stages of gestation.

RE SANCHEZHans NauwynckF MCNEILLYGM ALLANMaurice Pensaert

A1 Journal Article in VETERINARY MICROBIOLOGY

Post-weaning multisystemic wasting syndrome (PMWS) : a review of selected literature

G ALLANC CHARREYREMaurice PensaertHans NauwynckA BOTNERK MCCULLOUGH

Prevalence of canine herpesvirus in kennels and the possible association with fertility problems and neonatal death.

S VAN GUCHTHans NauwynckMaurice Pensaert

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Prevalentie van het caniene herpesvirus in kennels en het mogelijk verband met vruchtbaarheidsproblemen en neonatale sterfte.

Steven Van GuchtHans NauwynckMaurice Pensaert

A3 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

The clinical, pathological and microbiological outcome of an Escherichia coli O2: K1 infection in avian pneumovirus infected turkeys.

Saskia Van De ZandeHans NauwynckMaurice Pensaert

A1 Journal Article in VETERINARY MICROBIOLOGY

The role of clathrin and actin in antibody-induced internalization of viral glycoproteins in pseudorabies virus-infected monocytes

Gerlinde Van de WalleHerman FavoreelHans NauwynckPatric Van OostveldtMaurice Pensaert

A4 Journal Article in BIOCONCEPTS

Transmission of porcine circovirus type 2 from the sow to the litter.

Maurice PensaertRE SANCHEZHans Nauwynck

2000

A potential role for tumour necrosis factor-alpha in synergy between porcine respiratory coronavirus and bacterial lipopolysaccharide in the induction of respiratory disease in pigs.

Kristien Van ReethHans NauwynckMaurice Pensaert

A1 Journal Article in JOURNAL OF MEDICAL MICROBIOLOGY

Antibody-induced endocytosis of viral glycoproteins, expressed on pseudorabies virus-infected monocytes protects these cells from complement-mediated lysis.

Herman FavoreelHans NauwynckP VAN OOSTVELDTMaurice Pensaert

A2 Journal Article in VETERINARY RESEARCH

Differentiation of European and North-American serotypes of PRRSV: prevalence and vaccine efficacy

P VAN WOENSELGeoffrey LabarqueHans NauwynckG PAULA BONDE LARSENA EGGENN VISSER

Duration of cross-protection between subtypes A and B avian pneumovirus in turkeys.

Saskia Van De ZandeHans NauwynckC NAYLORMaurice Pensaert

A1 Journal Article in VETERINARY RECORD

Effect of cellular changes and onset of humoral immunity on the replication of porcine reproductive and respiratory syndrome virus in the lungs of pigs.

Geoffrey LabarqueHans NauwynckKristien Van ReethMaurice Pensaert

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Efficacy of an American and a European serotype PRRSV vaccine after challenge with American and European wild-type strains of the virus.

Geoffrey LabarqueHans NauwynckP VAN WOENSELN VISSERMaurice Pensaert

A2 Journal Article in VETERINARY RESEARCH

Equine herpesvirus type 1 abortion, neonatal foal death and nervous system disorders diagnosed in Belgium in 1999.

Karen van der MeulenHans NauwynckMaurice Pensaert

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Evolution of antibodies in pigs infected with porcine circovirus type 2 in the presence of maternally derived antibodies.

Geoffrey LabarqueHans NauwynckMaurice Pensaert

Functions of viral glycoproteins in the pathogenesis of Aujeszky's disease virus in pigs.

Hans NauwynckHerman FavoreelMaurice Pensaert

A2 Journal Article in VETERINARY RESEARCH

Het Post-weaning multisystemic wasting syndrome in België.

P VYTGeoffrey LabarqueMyra BosHans NauwynckStefan RoelsC MIRYMaurice PensaertRichard Ducatelle

A3 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Immunological hiding of herpesvirus-infected cells - Brief review.

Herman FavoreelMaurice PensaertHans Nauwynck

A1 Journal Article in ARCHIVES OF VIROLOGY

In vitro fertilization rate after incubation of bovine spermatozoa with cytopathic and noncytopathic bovine viral diarrhea virus

M TALEBKHAN GAROUSSIAnn Van SoomGeert VanrooseHans NauwynckSofie TangheHans LaevensAart de Kruif

Invasion and spread of a gG-deleted mutant of Aujeszky's disease virus (Suid Herpesvirus 1) in the olfactory nervous pathway of neonatal pigs.

SK KRITASHans NauwynckMaurice PensaertKonstantinos Kyriakis

A2 Journal Article in Hellenic Virology

PRRSV-macrophage interaction and putative receptors.

Hans NauwynckX DUANMaurice Pensaert

A2 Journal Article in VETERINARY RESEARCH

Pathogenesis of chronic viral diseases in cats

Prevalence of porcine circovirus type 2 in the Belgian pig population

P VYTGeoffrey LabarqueMaurice PensaertHans NauwynckC MIRYFrans Castryck

Proinflammatory cytokines and viral respiratory disease in pigs.

Kristien Van ReethHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Protection of avian pneumovirus (APV)-vaccinated turkeys against an APV/E. Coli challenge

Saskia Van De ZandeHans NauwynckMaurice Pensaert

Protection of neonatal pigs from Aujeszky's disease virus (Suid Herpesvirus 1) by administration of virus-specific non-neutralizing monoclonal antibodies.

SK KRITASHans NauwynckMaurice PensaertKonstantinos Kyriakis

A2 Journal Article in Hellenic Virology

Replication of equine herpesvirus type 1 in freshly isolated equine peripheral blood mononuclear cells and changes in susceptibility following mitogen stimulation.

Karen van der MeulenHans NauwynckW BUDDAERTMaurice Pensaert

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Role of anti-gB and -gD antibodies in antibody-induced endocytosis of viral and cellular cell surface glycoproteins expressed on pseudorabies virus-infected monocytes

Herman FavoreelHans NauwynckPatric Van OostveldtMaurice Pensaert

A1 Journal Article in VIROLOGY

Seroprevalence of porcine circovirus types 1 and 2 in the Belgian pig population.

Abraham MesuGeoffrey LabarqueHans NauwynckMaurice Pensaert

A1 Journal Article in VETERINARY QUARTERLY

Structural aspects of the zona pellucida of in vitro-produced bovine embryos: a scanning electron and confocal laser scanning microscopic study

Geert VanrooseHans NauwynckAnn Van SoomMarie-Thérèse YsebaertGerard CharlierPatric Van OostveldtAart de Kruif

A1 Journal Article in BIOLOGY OF REPRODUCTION

The "post-weaning multisystemic wasting syndrome" in Belgium.

P VYTGeoffrey LabarqueMyra BosHans NauwynckStefan RoelsC MIRYMaurice PensaertRichard Ducatelle

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

The EU struggle against Aujeszky's disease

A2 Journal Article in PIG PROGRESS (DOETINCHEM)

Use of monoclonal antibodies to prevent bovine herpesvirus-1-induced inhibition of the sperm cell-zona pellucida binding

Geert VanrooseHans NauwynckA VAN SOOME THIRYAart de Kruif

1999

Antibody-induced endocytosis of viral glycoproteins and major histocompatibility complex class I on pseudorabies virus-infected monocytes.

Herman FavoreelHans NauwynckHM HALEWYCKPatric Van OostveldtTC METTENLEITERMaurice Pensaert

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Antibody-induced endocytosis of viral glycoproteins, expressed on pseudorabies virus-infected monocytes protects these cells from complement-mediated lysis.

Herman FavoreelHans NauwynckMaurice Pensaert

Comparative pathogenesis of a subtype A with a subtype B avian pneumovirus in turkeys.

Saskia Van De ZandeHans NauwynckSandra De JongheMaurice Pensaert

A1 Journal Article in AVIAN PATHOLOGY

Differential production of proinflammatory cytokines in the pig lung during different respiratory virus infections : correlations with pathogenicity

Kristien Van ReethGeoffrey LabarqueHans NauwynckMaurice Pensaert

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

Effect of a successive intranasal/intramuscular vaccination strategy on the circulation of Aujeszky's disease virus in fattening pigs in persistently infected farrow-to-finish herds.

Dominiek MaesHans NauwynckLuk WillemsMaurice Pensaert

A1 Journal Article in VETERINARY RECORD

Effect of avian pneumovirus on the outcome of an Escherichia coli infection in turkeys.

Saskia Van De ZandeHans NauwynckMaurice Pensaert

Effect of bovine herpesvirus-1 or bovine viral diarrhea virus on development of in vitro-produced bovine embryos

Geert VanrooseHans NauwynckAnn Van SoomE VanopdenboschAart de Kruif

A1 Journal Article in MOLECULAR REPRODUCTION AND DEVELOPMENT

Effect of the interaction between bovine herpesvirus-1 and sperm cells on the in vitro fertilization of bovine oocytes

Geert VanrooseHans NauwynckA VAN SOOMM YSEBAERTAart de Kruif

Efficacy of an American and a European serotype PRRSV vaccine after challenge with American and European wild-type strains of the virus.

Geoffrey LabarqueHans NauwynckP VAN WOENSELMaurice PensaertN VISSER

Efficacy of an intranasal immunization with gEgC and gEgI double-deletion mutants of Aujeszky's disease virus in maternally immune pigs and the effects of a successive intramuscular booster with commercial vaccines.

Hans NauwynckGeoffrey LabarqueMaurice Pensaert

A1 Journal Article in JOURNAL OF VETERINARY MEDICINE SERIES B-INFECTIOUS DISEASES AND VETERINARY PUBLIC HEALTH

Entry of porcine reproductive and respiratory syndrome virus into porcine alveolar macrophages via receptor-mediated endocytosis.

Hans NauwynckX DUANHerman FavoreelPatric Van OostveldtMaurice Pensaert

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Functions of viral glycoproteins in the pathogenesis of Aujeszky's disease virus in pigs.

Hans NauwynckHerman FavoreelMaurice Pensaert

Groeistilstand en wegkwijnen bij gespeende biggen: een nieuw virus-geassocieerd ziektesyndroom.

Geoffrey LabarqueHans NauwynckKristien Van ReethMaurice Pensaert

A3 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Infection of fattening pigs by a virulent strain of Aujeszky's disease virus and its spread in the pig

SK KritasHans NauwynckMaurice PensaertKonstantinos Kyriakis

A2 Journal Article in BULLETIN OF THE HELLENIC VETERINARY MEDICAL SOCIETY

Neural invasion of two virulent Suid Herpesvirus 1 strains in neonatal pigs with or without maternal immunity.

SK KRITASMaurice PensaertHans NauwynckKonstantinos Kyriakis

A1 Journal Article in VETERINARY MICROBIOLOGY

PRRSV-macrophage interaction and putative receptors.

Hans NauwynckX DUANMaurice Pensaert

Prevalence of herds with young sows seropositive to pseudorabies (Aujeszky's disease) in northern Belgium.

F BOELAERTHubert DeluykerDominiek MaesJ GODFROIDA RASKINH VAREWIJCKMaurice PensaertHans NauwynckFrans CastryckC MIRY et al.

A1 Journal Article in PREVENTIVE VETERINARY MEDICINE

Protection of fattening pigs against challenge with Aujeszky's disease virus after a successive intranasal/intramuscular vaccination.

Geoffrey LabarqueHans NauwynckDominiek MaesMaurice Pensaert

A1 Journal Article in VETERINARY QUARTERLY

Role of the cytoplasmic tail of gE in antibody-induced redistribution of viral glycoproteins expressed on pseudorabies-virus-infected cells.

Herman FavoreelHans NauwynckMaurice Pensaert

A1 Journal Article in VIROLOGY

Safety of genetically engineered vaccines against suid herpesvirus, 1 : comparison of gE- and TK- single deleted mutants in the pig

SK KritasHans NauwynckMaurice PensaertKonstantinos Kyriakis

A2 Journal Article in ΕΛΛΗΝΙΚΗ ΙΟΛΟΓΙΑ = HELLENIC VIROLOGY

Why is the zona pellucida of in vitro-produced bovine embryos an efficient barrier for viral infection?: a scanning electron and confocal laser scanning microscopic study

Geert VanrooseHans NauwynckAnn Van SoomMaria YsebaertG CharlierPatric Van OostveldtAart de Kruif

1998

Bronchoalveolar interferon-alpha, tumor necrosis factor-alpha, interleukin-1, and inflammation during acute influenza in pigs: A possible model for humans?

Kristien Van ReethHans NauwynckMaurice Pensaert

A1 Journal Article in JOURNAL OF INFECTIOUS DISEASES

Identification of a putative receptor for porcine reproductive and respiratory syndrome virus on porcine alveolar macrophages

Xiaobo DuanHans NauwynckHerman FavoreelMaurice Pensaert

A1 Journal Article in JOURNAL OF VIROLOGY

Infections and reinfections with avian pneumovirus subtype A and B on Belgian turkey farms and relation to respiratory problems.

Saskia Van De ZandeHans NauwynckD CAVANAGHMaurice Pensaert

A1 Journal Article in JOURNAL OF VETERINARY MEDICINE SERIES B-INFECTIOUS DISEASES AND VETERINARY PUBLIC HEALTH

Paardenherpesvirus type 1 en 4 infecties : een overzicht

Wim BuddaertHans NauwynckMaurice Pensaert

A2 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Porcine reproductive and respiratory syndrome virus infection of alveolar macrophages can be blocked by monoclonal antibodies against cell surface antigens.

X DUANHans NauwynckHerman FavoreelMaurice Pensaert

A1 Journal Article in CORONAVIRUSES AND ARTERIVIRUSES

Recombinant porcine IFN-γ potentiates the secondary IgG and IgA responses to an inactivated suid herpesvirus-1 vaccine and reduces postchallenge weight loss and fever in pigs

Koen VandenbroeckHans NauwynckAnita VanderpootenKristien Van ReethBruno GoddeerisAlfons Billiau

A1 Journal Article in JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Replication of cytopathic and noncytopathic bovine viral diarrhea virus in zona-free and zona-intact in vitro-produced bovine embryos and the effect on embryo quality.

Geert VanrooseHans NauwynckAnn Van SoomE VANOPDENBOSCHAart de Kruif

A1 Journal Article in BIOLOGY OF REPRODUCTION

1997

Antibody-induced and cytoskeleton-mediated redistribution and shedding of viral glycoproteins, expressed on pseudorabies virus-infected cells

Herman FavoreelHans NauwynckPatric Van OostveldtThomas C MettenleiterMaurice Pensaert

A1 Journal Article in JOURNAL OF VIROLOGY

Effect of an infection with cytopathic bovine viral diarrhea virus on the quality of zona pellucida-free bovine in vitro produced morulae and hatched blastocysts

Geert VanrooseHans NauwynckA VAN SOOME VANOPDENBOSCHAart de Kruif

Effect of the concentration of maternal antibodies on the neural invasion of Aujeszky's disease virus in neonatal pigs.

SK KRITASHans NauwynckMaurice PensaertKonstantinos Kyriakis

A1 Journal Article in VETERINARY MICROBIOLOGY

Effects of origin and state of differentiation and activation of monocytes/macrophages on their susceptibility to porcine reproductive and respiratory syndrome virus (PRRSV).

X DUANHans NauwynckMaurice Pensaert

A1 Journal Article in ARCHIVES OF VIROLOGY

Feliene infectieuze peritonitis bij de kat : een overzicht

A2 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Functional aspects of Aujeszky's disease (pseudorabies) viral proteins with relation to invasion, virulence and immunogenicity.

A1 Journal Article in VETERINARY MICROBIOLOGY

Prevalentie van respiratoire en lymfotrope virussen bij kalkoenen in Belgie = Prevalence of respiratory and lymphotropic viruses in turkeys in Belgium

S VAN DE ZANDEHans NauwynckW HENDRICKXMaurice Pensaert

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Replication of cytopathic bovine viral diarrhea virus in zona pellucida-free in vitro produced embryos208

Geert VanrooseHans NauwynckA VAN SOOME VANOPDENBOSCHAart de Kruif

Susceptibility of zona-intact and zona-free in vitro-produced bovine embryos at different stages of development to infection with bovine herpesvirus-1

Geert VanrooseHans NauwynckAnn Van SoomE VanopdenboschAart de Kruif

A1 Journal Article in THERIOGENOLOGY

Virus quantification and identification of cellular targets in the lungs and lymphoid tissues of pigs at different time intervals after inoculation with porcine reproductive and respiratory syndrome virus (PRRSV).

X DUANHans NauwynckMaurice Pensaert

A1 Journal Article in VETERINARY MICROBIOLOGY

1996

Differences in neuroinvasiveness of two strains of Aujeszky's disease virus (ADV) in maternally immune pigs

S KRTTASMaurice PensaertHans NauwynckKonstantinos Kyriakis

Dual infections of feeder pigs with porcine reproductive and respiratory syndrome virus followed by porcine respiratory coronavirus or swine influenza virus: a clinical and virological study

Kristien Van ReethHans NauwynckMaurice Pensaert

A1 Journal Article in VETERINARY MICROBIOLOGY

Onderzoek in de veterinaire microbiologie: vroeger, nu en straks.

Freddy HaesebrouckHans Nauwynck

A3 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Research in veterinary microbiology yesterday, today and tomorrow.

Freddy HaesebrouckHans Nauwynck

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Virological protection against Aujeszky's disease virus in breeding sows vaccinated with inactivated or attenuated vaccines

Veerle ZonnekeynHans NauwynckMaurice Pensaert

1995

AN EPIDEMIC OF FATAL HEPATIC-NECROSIS OF VIRAL ORIGIN IN RACING PIGEONS (COLUMBA-LIVIA).

Peter De HerdtRichard DucatelleC LEPOUDREG CHARLIERHans Nauwynck

A1 Journal Article in AVIAN PATHOLOGY

An epidemic of fatal hepatic necrosis of viral origin in pigeons

Peter De HerdtRichard DucatelleCindy LepoudreG CHARLIERHans Nauwynck

A2 Journal Article in AVIAN PATHOLOGY

Cell-free and cell-associated viraemia in pigs after oronasal infection with Aujeszkys-disease virus.

Hans NauwynckMaurice Pensaert

A1 Journal Article in VETERINARY MICROBIOLOGY

Dissemination of wild-type and gC-, gE- and gl-deleted mutants of Aujeszky's disease virus in the maxillary nerve and trigeminal ganglion of pigs after intranasal inoculation.

SK KRITASHans NauwynckMaurice Pensaert

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Effect of specific antibodies on the cell-associated spread of pseudorabies virus in monolayers of different cell-types.

Hans NauwynckMaurice Pensaert

A1 Journal Article in ARCHIVES OF VIROLOGY

Porcine reproductive and respiratory syndrome.

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

ROLE OF GLYCOPROTEIN GD IN THE ADHESION OF PSEUDORABIES VIRUS-INFECTED CELLS AND SUBSEQUENT CELL-ASSOCIATED VIRUS SPREAD.

FP HANSSENSHans NauwynckTC METTENLEITER

A1 Journal Article in ARCHIVES OF VIROLOGY

1994

Interactions of Aujeszkys-disease virus and porcine blood mononuclear cells in-vivo and in-vitro.

Hans NauwynckMaurice Pensaert

A1 Journal Article in ACTA VETERINARIA HUNGARICA

TESTING FOR FELINE ENTERIC CORONAVIRUS IN CATS.

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Virus production and viral-antigen expression in porcine blood monocytes ino culated with pseudorabies virus.

Hans NauwynckMaurice Pensaert

A1 Journal Article in ARCHIVES OF VIROLOGY

1993

INVOLVEMENT OF MEMBRANE-BOUND VIRAL GLYCOPROTEINS IN ADHESION OF PSEUDORABIES VIRUS-INFECTED CELLS.

FP HANSSENSHans NauwynckMaurice Pensaert

A1 Journal Article in JOURNAL OF VIROLOGY

Membrane bound viral glycoproteins gll, gill and gp50 are involved in adhesion of pseudorabies virus infected cells

F HANSSENSHans NauwynckMaurice Pensaert

Susceptibility of hares and rabbits to a Belgian isolate of European brown hare syndrome virus

Hans NauwynckPaul CallebautJohan PeetersRichard DucatelleErik Uyttebroek

A1 Journal Article in JOURNAL OF WILDLIFE DISEASES

The cell-associated spread of Aujeszky's disease virus (pseudorabies virus) and its possible role in vaccinated sows

Hans NauwynckMaurice Pensaert

1992

ABORTION INDUCED BY CELL-ASSOCIATED PSEUDORABIES VIRUS IN VACCINATED SOWS.

Hans NauwynckMaurice Pensaert

A1 Journal Article in AMERICAN JOURNAL OF VETERINARY RESEARCH

INFECTIOUS BOVINE-RHINOTRACHEITIS VACCINE FOR CATTLE.

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Susceptibility of hares and rabbits to a Belgian isolate of European Brown Hare Syndrome (EBHS) virus

Hans NauwynckP CALLEBAUTJE PEETERSRichard DucatelleErik Uyttebroek

A2 Journal Article in The journal of applied rabbit research

1990

Het nefropathogeen infectieus bronchitis virus (NIBV): een overzicht

Hans NauwynckMaurice Pensaert

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

An intranasal/intramuscular vaccination approach in view of an accelerated elimination of Aujeszky's disease virus in regions with high prevalence. Proceedings 15th Int. Pig Vet. Soc. Congress, Birmingham, U.K., 1998, 185.

Hans NauwynckGeoffrey LabarqueKristien Van ReethMaurice Pensaert

Cell membrane bound viral glycoproetins gll and gill are involved in adhesion of pseudorabies infected cells to an uninfected monolayer, the receptor is heparan sulfate. Symposium on Entry of Microorganisms into Host Cells, Brussel, 1993, 10-12.

F HANSSENSHans NauwynckMaurice Pensaert

Field evaluation of the efficacy of an intranasal/intramuscular vaccination approach in pigs with different status of maternal immunity. Proceedings 15th Int. Pig Vet. Soc. Congress, Birmingham, U.K., 1998, 184.

Geoffrey LabarqueHans NauwynckKristien Van ReethMaurice Pensaert

Pathogenesis of combined infection with porcine reproductive-respiratory syndrome virus (PRRSV) and swine influenza virus (SIV). Proceedings 15th Int. Pig Vet. Soc. Congress, Birmingham, U.K., 1998, 264.

Kristien Van ReethGeoffrey LabarqueHans NauwynckMaurice Pensaert

Pathogenic features of pseudorabies virus infection in swine with implications to control. Proc.: 1st Intern. Symposium on Eradication of Pseudorabies (Aujeszky's) virus. Published by the University of Minnesota, St. Paul, Minnesota, USA, 1992, p. 1 -16.

Maurice PensaertHans NauwynckK DESMET

Pro-inflammatory cytokines and lung pathology after combined exposure to porcine respiratory coronavirus (PRCV) and bacterial endotoxines. Proceedings 15th Int. Pig Vet. Soc. Congress, Birmingham, U.K., 1998, 193.

Kristien Van ReethHans NauwynckMaurice Pensaert

Programmes for the eradication of Aujeszky's disease virus (pseudorabies virus) in the member states of the European Union. Proceedings of the O.I.E. Sympo sium 'Aujeszky's Disease', Bangkok, Thailand, 1994,55-66.

Hans NauwynckMB PENSAERT

Replication of virulent Aujeszky's disease virus (ADV) in different blood mononuclear cell subpopulations. Proc.: 12th Intern. Pig Vet. Soc. Congress, The Hague, The Netherlands, 1992, p. 63.

Hans NauwynckMaurice PensaertBruno Goddeeris

Role of porcine reproductive and respiratory syndrome virus in reproductive failure of sows. Proceedings 10th European A.I. Vets Meeting. Bruges, Belgium, 1998, 5 p.

Susceptibility of hares and rabbits to a Belgian isolate of European Brown Hare Syndrome (EBHS) virus. Proc. of the 5th World Rabbit Congress, Oregon State University, (25-30/7/92) (Poster).

Hans NauwynckP CALLEBAUTJ PEETERSRichard DucatelleErik Uyttebroek