Project

Characterization of the infection and invasion of alphaherpesviruses in the respiratory and genital mucosae.

Code
01D15319
Duration
01 October 2019 → 30 September 2023
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Agricultural and food sciences
    • Veterinary microbiology
Keywords
Alphaherpesvirus pathogenesis respiratory mucosa genital mucosa replication characteristics invasion
 
Project description

Alphaherpesviruses invade respiratory and genital mucosae. With the present project, we want to examine how they do this. First, the barrier function of the tight junctions will be studied in both mucosae and the basolaterally localized receptor will be identified. Next, the proteases that are
involved in the basement membrane crossing will be identified and their induction will be examined.