Code
01P14510
Duration
01 October 2010 → 01 October 2012
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Natural sciences
- Microbiology
- Systems biology
-
Medical and health sciences
- Immunology
- Laboratory medicine
- Microbiology
- Immunology
- Laboratory medicine
- Microbiology
- Immunology
- Laboratory medicine
- Microbiology
-
Engineering and technology
- Biomaterials engineering
- Biological system engineering
- Biomaterials engineering
- Biomechanical engineering
- Other (bio)medical engineering
- Environmental engineering and biotechnology
- Industrial biotechnology
- Other biotechnology, bio-engineering and biosystem engineering
Keywords
cell-directed therapy
macrophages
immunoconjugates
toxin
antigen
Project description
Apart from their essential and vital homeostatic role, macrophages are also involved in many pathological conditions and they can function as a hiding place for intracellular pathogens. The use of macrophage-restricted molecules as a gateway for therapeutic immunoconjugates will be evaluated as a strategy to combat severl diseases