Project

Molecular analysis of the cytoplasmic tail of sialoadhesin, the driving force behind this multifunctional receptor. As well as analysis of the pathways that are altered upon ligand-induced sialoadhesin endocytosis, and the effect on antigen presentation

Code
3E016212
Duration
01 October 2012 → 30 September 2015
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Immunology
    • Laboratory medicine
    • Microbiology
  • Engineering and technology
    • Biomaterials engineering
    • Biological system engineering
    • Biomaterials engineering
    • Biomechanical engineering
    • Other (bio)medical engineering
    • Environmental engineering and biotechnology
    • Industrial biotechnology
    • Other biotechnology, bio-engineering and biosystem engineering
Keywords
endocytosis signalling sialoadhesin CD169 Siglec-1 antigen presentation
 
Project description

Molecular analysis of the cytoplasmic tail of sialoadhesin, the driving force behind this multifunctional receptor. As well as analysis of the pathways that are altered upon ligand-induced sialoadhesin endocytosis, and the effect on antigen presentation.