Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process.

Doctoral project Arun Kumar Tharkeshwar Raghunath

Doctoral project Chloé Van Leene

Doctoral project Eline Schillebeeckx

Doctoral project Jarne Pauwels

Doctoral project Jolien Hollebeke

Doctoral project Kim Plasman

Doctoral project Niklaas Colaert

Shifting mass spectrometry based proteomics to the fast lane: An interplay between high throughput LC and data independent acquisition without compromising depth, precision or accuracy

Studying Protein Complexes for Assessing the Function of Ghost Proteins (Ghost in the Cell)

The influence of protein N-terminal acetylation on protein conformation

Understanding persistent tumour cell biology by means of single-cell proteomics

A Tale of Tissue and Text: Predictive proteome profiling and managing metadata mayhem

Capturing the phosphorylation landscape during regulation of nodulation for sustainable use of nitrogen in soybean cultivation.

Capturing the ubiquitination and protein interaction landscape of the central regulator of nodulation TOO MUCH LOVE in soybean.

Doctoral project Alan Walton

Doctoral project Andreia Sofia da Costa de Monica Ferreira

Doctoral project Daniel Bruznican

Doctoral project Els Timmerman

Doctoral project Lam Dai Vu

Doctoral project Ludger Goeminne

Doctoral project Lukas Braem

Doctoral project Nina Turk

Doctoral project Patrick Willems

Doctoral project Shanshuo Zhu

Doctoral project Silke Jacques

Doctoral project Styliani Tsiatsiani

Effect of diet on gut physiology: a proteomics approach in the pig

Novel glycoproteomics methodology for discovering tumor-specific, cell surface, glycopeptide epitopes

Persuasion is better then force. How <i>Caulobacter</i> RHG1 convinces <i>Arabidopsis thaliana</i> of its beneficial character

Phosphorylation and ubiquitination-mediated signalling in Arabidopsis root and hypocotyl growth

Prediction of surgical resectability after FOLFIRINOX chemotherapy for borderline resectable (BR) and locally advanced pancreatic cancer (LADPA)

Proteome-wide analysis of high temperature effect on protein structures in Arabidopsis.

The bait tastes first the fish. Towards a better understanding of strigolactone signalling.

Alternative translation initiation unraveled by N-terminomics and ribosome profiling: the landscape of novel N-terminal protein variants, their stability and localization

A MALDI-8020 mass spectrometer for peptide and protein analysis.

Are amino-terminal proteoforms engaged in different protein complexes?

Assessing the dynamic interplay between protein phosphorylation and O-linked-N-acetylglucosamine

Automated sample preparation for mass spectrometry-based proteomics using the DigestPro MSi instrument.

Automated sample preparation for single-cell mass spectrometry-based proteomics

'BacVirISG15' - in the framework of ERA-NET Infect-ERA JTC 2016. The Interferon Stimulated Gene 15 (ISG15) modification system in host pathogen interactions: mechanisms, technology and translational potential.

Bioinformatics: from nucleotids to networks (N2N)

Cathepsins in cell death

Characterization of N-acetyltransferases, and the study of N-terminal protein acetylation

Characterization of the ACR4-AUR1/2-PP2A phosphorylation module in root growth

Detailed analysis of the substrates and the specificity of the N-terminalacetyltransferases

Detailed proximal protein profiling of endogenous p53 in colon cancer cells

Development of a fully operational single-cell proteomics pipeline for the investigation of minimal residual disease in melanoma

Development of chemical tools and proteomics methodology for the study of proteolytic systems (ChemProTools)

Development of C-terminal peptide-based proteome-analytical strategies and the extensive mapping of the granzyme substrate-repertoire

Endogenous tagging of scaffold proteins: profiling switches in signal transduction pathways

Enrichment of extracellular vesicles for discovery of biomarkers for early cancer diagnosis

Evaluation of p53 aggregation as a drug target in oncology

Extracellular vesicle (EV) transport across the brain barriers: from mechanistic and biological insights towards strategies for delivery of therapeutics to the brain.

Granzyme-mediated cell-targeted and antiviral methods-of-action: a targeted proteomic analysis

Integrated proteome-centric analysis of immune regulation

Interactome and degradome analysis of signaling pathways leading to activation of the inflammasome complexes.

Introducing PPI-iMixPro, a novel technology to characterize protein complexes

Preclinical validation of a less toxic variant for paediatric leukemia

Probing the proteome structure in living cells

Proteases in inflammation and cell death

Protein Modifications Associated with Oxidative and Nitrative Stress: a Gel-free Proteome Analysis

Proteomics Expertise Center Ugent

Restoration of p53 function for antimelanoma combination therapy

Study of protein-protein interaction networks in intact cells and application on the leptin receptor

Targeted, peptide-centric proteome analytical characterization of the substrates of human alpha-N-acetyltrasnferases

Targeting aberrant DNA methylation in T-cell acute lymphoblastic leukemia (T-ALL) and lymphoma (T-LBL)

The function and interactome of protein aggregates

The influence of protein N-terminal acetylation on protein conformation

The Porcupine Neogene Paleoceanografische revolution: timing and flown for the nucleation of (carbonate) mounds and model studies of turbidites and contourieten (IODP expedite 307)

The role of cathepsins in apoptosis and antigen presentation studied by positional proteomics

Validation of a biomarker panel for the diagnosis of malignant pleural mesothelioma

W&T beurs Betancourt L.

A computational pipeline for highly sensitive profiling of tissue leakage proteins in liquid biopsies

A new fragment-centric perspective on proteomics

Capturing the phosphorylation and interaction landscape of NARK, the central kinase controlling nodulation in soybean

Capturing the phosphorylation landscape during regulation of nodulation for sustainable use of nitrogen in soybean cultivation

Capturing the phosphorylation landscape during regulation of nodulation for sustainable use of nitrogen in soybean cultivation

Capturing the ubiquitination and protein interaction landscape of the central regulator of nodulation TOO MUCH LOVE in soybean

Circumventing the Biological Obstacles of anti-inflammatory Glucocorticoid Therapy

Computational analysis and integration of accross-Omics data

Development and functional characterization of inhibitors targeting specific inflammatory caspases

Does HR need an MC?

Exploring the therapeutic effect of Akt2/PKB- Beta –neutralising nanobodies in cancer cells

Extracellullar vesicle signatures as biomarker of therapeutic efficiency in metastatic breast cancer

Identification and functional evaluation of Arabidopsis metacaspase substrates

Identifying and characterizing the ubiquitinylation substrates of the central leaf growth and senescence regulator, BIG BROTHER

Identifying thermosensory protein complexes in plants

Interactome and degradome analysis of signaling pathways leading to activation of the inflammasome complexes.

Metacaspase degradome in plant cell death

Microbial electrochemical technologies for sustainable critical metal Recovery  

PHF6: a new tumor suppressor gene in T-cell acute lymphoblastic leukemia

Post-translational modifications during the oxidative stress response in plants.

Study of the plasticity of the Glucocorticoid Receptor using selective modulators.

Systemic redoxome profiling in plants: catching the ROS wave

The molecular basis of the growth promoting capacity of a Caulobacter sp. on Arabidopsis thaliana

Multi-omics approach to identify pancreatic cancer biomarkers in liquid biopsies of advanced stage patients by pioneering single cell mass spectrometry of CTCs and (epi)genetics characterization of cfDNA