Research Explorer

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Researcher

Kris Gevaert

Awards & Distinctions

503 Results

2024

Glucocorticoid receptor signaling : intricacies and therapeutic opportunities

Dorien ClarisseLaura Van MoortelChloé Van LeeneKris GevaertKarolien De Bosscher

A1 Journal Article in TRENDS IN BIOCHEMICAL SCIENCES

Heterodimerization domains in MAP4 KINASEs determine subcellular localization and activity in Arabidopsis

Lixia PanCássio Flávio Fonseca de LimaLam Dai VuBrigitte Van De CotteNancy De WinneKris GevaertGeert De JaegerIve De Smet

U Journal Article in Plant Physiology

Phosphoproteome analyses pinpoint the F‐box protein SLOW MOTION as a regulator of warm temperature‐mediated hypocotyl growth in Arabidopsis

Shanshuo ZhuLixia PanLam Dai VuXiangyu XuBeatriz Orosa‐PuenteTingting ZhuPia NeytBrigitte Van De CotteTom JacobsJoshua M. Gendron et al.

A1 Journal Article in NEW PHYTOLOGIST

Selective modulation of the human glucocorticoid receptor compromises GR chromatin occupancy and recruitment of p300/CBP and the Mediator complex

Laura Van MoortelAnnick VerheeJonathan ThommisRené HoutmanDiana MelchersLouis DelhayeChloé Van LeeneMadeleine HellemansKris GevaertSven Eyckerman et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Towards improved Parsortix® efficiency for circulating tumor cell enrichment in pancreatic cancer

Nele VandenbusscheBéatrice LintermansTijs MerckaertKris GevaertKathleen Claes

2023

A decoupled Virotrap approach to study the interactomes of N-terminal proteoforms

Annelies BogaertTessa Van de SteeneMarnik VuylstekeSven EyckermanKris Gevaert

Bookchapter in Methods in enzymology

A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment

Elly De VlieghereKoen Van de VijverEva BlondeelNathan CarpentierRouba GhobeiraJarne PauwelsSebastian RiemannManon MinsartCharlotte FieuwsJohanna Mestach et al.

A1 Journal Article in BIOMATERIALS RESEARCH

Adaptor protein complex interaction map in Arabidopsis identifies P34 as a common stability regulator

Peng WangWei SiaoXiuyang ZhaoDeepanksha AroraRen WangDominique EeckhoutJelle Van LeeneRahul KumarAnaxi HoubaertNancy De Winne et al.

A1 Journal Article in NATURE PLANTS

Assessing recovery rates of mesenchymal and epithelial pancreatic tumor cells using the Parsortix system

Nele VandenbusscheBram PartonTijs MerckaertCharlotte FieuwsKris GevaertKathleen Claes

Cell surface biotinylation using furan cross-linking chemistry

Maria Fernandez FernandezLaia Miret CasalsAnnemieke MadderKris Gevaert

Bookchapter in Mass spectrometry-based proteomics

Complementary peptides represent a credible alternative to agrochemicals by activating translation of targeted proteins

M OrmanceyB GuillotinR MerretL CambordeC DuboéB FabreC PouzetFrancis ImpensDelphi Van HaverMC Carpentier et al.

A1 Journal Article in NATURE COMMUNICATIONS

Cornification of keratinocytes is associated with differential changes in the catalytic activity and the immunoreactivity of transglutaminase-1

Marta SurbekTessa Van de SteeneAttila Placido SachslehnerBahar GolabiJohannes GrissSven EyckermanKris GevaertLeopold Eckhart

A1 Journal Article in SCIENTIFIC REPORTS

CysQuant : simultaneous quantification of cysteine oxidation and protein abundance using data dependent or independent acquisition mass spectrometry

Jingjing HuangAn StaesFrancis ImpensVadim DemichevFrank Van BreusegemKris GevaertPatrick Willems

A1 Journal Article in REDOX BIOLOGY

Employing non-targeted interactomics approach and subcellular fractionation to increase our understanding of the ghost proteome

Diego Fernando Garcia del RioTristan CardonSven EyckermanIsabelle FournierAmelie BonnefondKris GevaertMichel Salzet

A1 Journal Article in ISCIENCE

Expanded in vivo substrate profile of the yeast N-terminal acetyltransferase NatC

Petra Van DammeCamilla OsbergVeronique JonckheereNina GlomnesKris GevaertThomas ArnesenHenriette Aksnes

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Increasing the overall proteome coverage by combining protein digestion by Tryp-N and trypsin

Jade HawksworthLode DenolfEvy TimmermanKris Gevaert

Bookchapter in Mass spectrometry-based proteomics

Machine learning on large-scale proteomics data identifies tissue and cell-type specific proteins

Tine ClaeysMaxime MenuRobbin BouwmeesterKris GevaertLennart Martens

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Macrophage resistance to ionizing radiation exposure is accompanied by decreased cathepsin D and increased transferrin receptor 1 expression

Ana Teresa PintoAna Beatriz MachadoHugo OsórioMarta Laranjeiro PintoRui VitorinoGonçalo JustinoCátia SantaFlávia CastroTânia CruzCarla Rodrigues et al.

A1 Journal Article in CANCERS

Multi-allergen quantification in food using concatemer-based isotope dilution mass spectrometry : a collaborative study

Maxime GavageKaatje Van VlierbergheMarc DieuPatsy RenardThierry ArnouldKris GevaertMarc De LooseChristof Van PouckeAnne-Catherine HuetNathalie Gillard

A1 Journal Article in JOURNAL OF AOAC INTERNATIONAL

Mutation of Arabidopsis SME1 and Sm core assembly improves oxidative stress resilience

Patrick WillemsValerie Van RuyskensveldeTakanori MarutaRobin PottieÁlvaro Daniel Fernández FernándezJarne PauwelsMatthew A. HannahKris GevaertFrank Van BreusegemKatrien Van Der Kelen

A1 Journal Article in FREE RADICAL BIOLOGY AND MEDICINE

N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity

Sylvia VarlandRui Duarte SilvaIne KjosåsAlexandra FaustinoAnnelies BogaertMaximilian BillmannHadi BoukhatmiBarbara KellenMichael CostanzoAdrian Drazic et al.

A1 Journal Article in NATURE COMMUNICATIONS

N-terminal proteoforms may engage in different protein complexes

Annelies BogaertDaria FijalkowskaAn StaesTessa Van de SteeneMarnik VuylstekeCharlotte StadlerSven EyckermanKerstin SpirohnTong HaoMichael A Calderwood et al.

A1 Journal Article in LIFE SCIENCE ALLIANCE

Novel glycoproteomics methodology for discovering tumor-specific, cell surface, glycopeptide epitopes

Wannes WeytsNico CallewaertKris GevaertSimon Devos

Protein interactors of 3-O sulfated heparan sulfates in human MCI and age-matched control cerebrospinal fluid

Andreia Sofia da Costa de Monica FerreiraEvy TimmermanAn StaesMarnik VuylstekeLouis De MuynckKris Gevaert

A1 Journal Article in SCIENTIFIC DATA

Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins

Livija TušarJure LobodaFrancis ImpensPiotr SosnowskiEmmy Van QuickelbergheRobert VidmarHans DemolKoen SedeynXavier SaelensMatej Vizovišek et al.

A1 Journal Article in COMMUNICATIONS BIOLOGY

Reduced levels of misfolded and aggregated mutant p53 by proteostatic activation

Evelyne NausMarleen DerweduweYoulia LampiAnnelies ClaeysJarne PauwelsTobias LangenbergFilip ClaesJie XuVeerle HaemelsZeynep Kalender Atak et al.

A1 Journal Article in CELLS

Shift in vacuolar to cytosolic regime of infecting Salmonella from a dual proteome perspective

Ursula FelsPatrick WillemsMargaux De MeyerKris GevaertPetra Van Damme

A1 Journal Article in PLOS PATHOGENS

Structure–function study of a Ca2+-independent metacaspase involved in lateral root emergence

Simon StaelIgor SabljićDominique AudenaertThilde AnderssonStyliani TsiatsianiRobert P. KumpfAndreu Vidal-AlbalatCecilia LindgrenDominique VercammenSilke Jacques et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Studying protein complexes for assessing the function of ghost proteins (ghost in the cell)

Diego Fernando Garcia del RioMichel SalzetKris GevaertAmélie BonnefondSven Eyckerman

Targeted profiling of protein phosphorylation in plants

Xiangyu XuKris GevaertIve De SmetLam Dai Vu

Bookchapter in Mass spectrometry-based proteomics

The quest for improved ligands : a study of the functional plasticity of the glucocorticoid receptor

Laura Van MoortelKarolien De BosscherKris Gevaert

Unraveling N-terminal proteoforms by N-terminomics and interactomics

Annelies BogaertKris Gevaert

lesSDRF is more : maximizing the value of proteomics data through streamlined metadata annotation

Tine ClaeysTim Van Den BosscheYasset Perez-RiverolKris GevaertJuan Antonio VizcaínoLennart Martens

A1 Journal Article in NATURE COMMUNICATIONS

α-1,6-fucosyltransferase plays a critical role during embryogenesis of the hemimetabolous insect Nilaparvata lugens

Qun YangGuy SmaggheAn StaesKris GevaertKristof De Schutter

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

2022

A new generation of AD biomarkers : 2019 to 2021

Jade HawksworthEsperanza FernándezKris Gevaert

A1 Journal Article in AGEING RESEARCH REVIEWS

A strong cation exchange chromatography protocol for examining N-terminal proteoforms

Esperanza FernándezAnnelies BogaertEvy TimmermanAn StaesFrancis ImpensKris Gevaert

Bookchapter in Yeast functional genomics : methods and protocols

Abnormal concentrations of acetylated amino acids in cerebrospinal fluid in acetyl‐CoA transporter deficiency

Katarina ŠikićTessa M. A. PetersEugenija MarušićIvana Čulo ČagaljDanijela Petković RamadžaTamara ŽigmanKsenija FumićEsperanza FernandezKris GevaertŽeljko Debeljak et al.

A1 Journal Article in JOURNAL OF INHERITED METABOLIC DISEASE

Binding of Orysata lectin induces an immune response in insect cells

Pengyu ChenKristof De SchutterJarne PauwelsKris GevaertEls Van DammeGuy Smagghe

A1 Journal Article in INSECT SCIENCE

Development and validation of a quantitative method for multiple allergen detection in food using concatemer-based isotope dilution mass spectrometry

Maxime GavageKaatje Van VlierbergheMarc DieuPatsy RenardThierry ArnouldMarc De LooseKris GevaertNathalie GillardChristof Van Poucke

A1 Journal Article in JOURNAL OF AOAC INTERNATIONAL

Limited evidence for protein products of non-coding transcripts in the HEK293T cellular cytosol

Annelies BogaertDaria FijalkowskaAn StaesTessa Van de SteeneHans DemolKris Gevaert

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Liquid biopsies to predict surgical resectability after FOLFIRINOX chemotherapy in patients with locally advanced and borderline resectable pancreatic ductal adenocarcinoma

Nele VandenbusscheLUIS ABREU DE CARVALHOKris GevaertKathleen Claes

Machine learning on large-scale proteomics data identifies tissue- and cell type-specific proteins

Tine ClaeysMaxime MenuRobbin BouwmeesterKris GevaertLennart Martens

Mapping the adaptor protein complex interaction network in Arabidopsis identifies P34 as a common stability regulator

Peng WangWei SiaoXiuyang ZhaoDeepanksha AroraRen WangDominique EeckhoutJelle Van LeeneRahul KumarAnaxi HoubaertNancy De Winne et al.

Mass spectrometry and the cellular surfaceome

Jarne PauwelsDaria FijalkowskaSven EyckermanKris Gevaert

A1 Journal Article in MASS SPECTROMETRY REVIEWS

Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets

Laura Van MoortelJonathan ThommisBrecht MaertensAn StaesDorien ClarisseDelphine De SutterClaude LibertOnno C. MeijerSven EyckermanKris Gevaert et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

Persuasion is better then force : how Caulobacter RHG1 convinces Arabidopsis thaliana of its beneficial character

Amber LampensSofie GoormachtigKris Gevaert

Proteome-wide cellular thermal shift assay reveals unexpected cross-talk between brassinosteroid and auxin signaling

Qing LuYonghong ZhangJoakim HellnerCaterina GianniniXiangyu XuJarne PauwelsQian MaWim DejongheHuibin HanBrigitte Van De Cotte et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNAi of Mannosidase‐Ia in the Colorado potato beetle and changes in the midgut and peritrophic membrane

Dongdong LiuKristof De SchutterJohann FarAn StaesKoen DewettinckLoic QuintonKris GevaertGuy Smagghe

A1 Journal Article in PEST MANAGEMENT SCIENCE

SAMBA controls cell division rate during maize development

Pan GongMichiel BontinckKirin DemuynckJolien De BlockKris GevaertDominique EeckhoutGeert PersiauStijn AesaertGriet CoussensMaria Van Lijsebettens et al.

A1 Journal Article in PLANT PHYSIOLOGY

Selecting processing robust markers using high resolution mass spectrometry for the detection of milk in food products

Kaatje Van VlierbergheMaxime GavageMarc DieuPatsy RenardThierry ArnouldNathalie GillardKatleen CoudijzerMarc De LooseKris GevaertChristof Van Poucke

A1 Journal Article in JOURNAL OF AOAC INTERNATIONAL

The final maturation state of β-actin involves N-terminal acetylation by NAA80, not N-terminal arginylation by ATE1

Adrian DrazicEvy TimmermanUlrike KajanMichaël MarieSylvia VarlandFrancis ImpensKris GevaertThomas Arnesen

A1 Journal Article in JOURNAL OF MOLECULAR BIOLOGY

Transcriptional analysis in the Arabidopsis roots reveals new regulators that link rac-GR24 treatment with changes in flavonol accumulation, root hair elongation and lateral root density

Sylwia Magdalena StrukLukas BraemCedrick MatthysAlan WaltonNick VangheluweStan Van PraetLingxiang JiangPawel Radoslaw BasterCarolien De CuyperFrançois-Didier Boyer et al.

A1 Journal Article in PLANT AND CELL PHYSIOLOGY

Triazolinedione protein modification : from an overlooked off-target effect to a tryptophan-based bioconjugation strategy

Klaas DecoeneKamil ÜnalAn StaesOlivier ZwaenepoelJan GettemansKris GevaertJohan WinneAnnemieke Madder

A1 Journal Article in CHEMICAL SCIENCE

2021

A Phelipanche ramosa KAI2 protein perceives strigolactones and isothiocyanates enzymatically

Alexandre de Saint GermainAnse JacobsGuillaume BrunJean-Bernard PouvreauLukas BraemDavid CornuGuillaume ClavéEmmanuelle BauduVincent SteinmetzVincent Servajean et al.

A1 Journal Article in PLANT COMMUNICATIONS

An AKT2-specific nanobody that targets the hydrophobic motif induces cell cycle arrest, autophagy and loss of focal adhesions in MDA-MB-231 cells

Tijs MerckaertOlivier ZwaenepoelKris GevaertJan Gettemans

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

Importance of extracellular vesicle secretion at the blood-cerebrospinal fluid interface in the pathogenesis of Alzheimer’s disease

Charysse VandendriesscheSriram BalusuCaroline Van CauwenbergheMarjana BrkicMarie PauwelsNele PlehiersArnout BruggemanPieter DujardinGriet Van ImschootElien Van Wonterghem et al.

A1 Journal Article in ACTA NEUROPATHOLOGICA COMMUNICATIONS

Mass spectrometry-based clinical proteomics : a revival

Jarne PauwelsKris Gevaert

Editorial material

Mechanisms of congenital heart disease caused by NAA15 haploinsufficiency

Tarsha L. WardWarren TaiSarah U. MortonFrancis ImpensPetra Van DammeDelphi Van HaverEvy TimmermanGabriela VenturiniKehan ZhangMin Young Jang et al.

A1 Journal Article in CIRCULATION RESEARCH

Prune-1 drives polarization of tumor-associated macrophages (TAMs) within the lung metastatic niche in triple-negative breast cancer

V FerrucciF AsadzadehF CollinaR SicilianoA BocciaL MarroneD SpanoM CarotenutoCM ChiarollaD De Martino et al.

A1 Journal Article in ISCIENCE

Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions

Glenn VergauwenJoeri TulkensCláudio PinheiroFrancisco Avila CobosSandor DedeyneMarie-Angélique De ScheerderLinos VandekerckhoveFrancis ImpensIlkka MiinalainenGeert Braems et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

The bait tastes first the fish : towards a better understanding of strigolactone signalling

Anse JacobsSofie GoormachtigKris Gevaert

The lectin Orysata induces phosphatase-mediated and carbohydrate-independent aggregation of insect cells

Pengyu ChenKristof De SchutterJarne PauwelsKris GevaertEls Van DammeGuy Smagghe

A1 Journal Article in JOURNAL OF INSECT PHYSIOLOGY

The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis

Lam Dai VuXiangyu XuTingting ZhuLixia PanMartijn van ZantemDorrit de JongYaowei WangTim VanremoorteleAnna M. LockeBrigitte Van De Cotte et al.

A1 Journal Article in NATURE COMMUNICATIONS

Unraveling the MAX2 protein network in Arabidopsis thaliana : identification of the protein phosphatase PAPP5 as a novel MAX2 interactor

Sylwia Magdalena StrukCarolien De CuyperAnse JacobsLukas BraemAlan WaltonAnnick De KeyserStephen DepuydtLam Dai VuIve De SmetFrançois-Didier Boyer et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Unravelling AKT2 signalling in cancer through nanobody technology

Tijs MerckaertJan GettemansKris Gevaert

Use of hybrid data-dependent and -independent acquisition spectral libraries empowers dual-proteome profiling

Patrick WillemsUrsula FelsAn StaesKris GevaertPetra Van Damme

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

2020

A mass spectrometer approach to understand strigolactone induced germination of Phelipanche ramosa

Lukas BraemSofie GoormachtigKris Gevaert

Bacterial genetic engineering by means of recombineering for reverse genetics

Ursula FelsKris GevaertPetra Van Damme

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Chemical genetics approach identifies abnormal inflorescence meristem 1 as a putative target of a novel sulfonamide that protects catalase2-deficient Arabidopsis against photorespiratory stress

Tom van der MeerArno VerleePatrick WillemsFrancis ImpensKris GevaertChrista TesterinkChristian StevensFrank Van BreusegemPavel Kerchev

A1 Journal Article in CELLS

Classification and nomenclature of metacaspases and paracaspases : no more confusion with caspases

Elena A. MininaJens StaalVanina E. AlvarezJohn A. BergesIlana Berman-FrankRudi BeyaertKay D. BidleFrédéric BornancinMagali CasanovaJuan J. Cazzulo et al.

A1 Journal Article in MOLECULAR CELL

Comparative study of concatemer efficiency as an isotope-labelled internal standard for allergen quantification

M GavageK Van VlierbergheC Van PouckeM De LooseKris GevaertM DieuP RenardT ArnouldP FileeN Gillard

A1 Journal Article in FOOD CHEMISTRY

Dehydrin ERD14 activates glutathione transferase Phi9 in Arabidopsis thaliana under osmotic stress

Phuong N NguyenMaria-Armineh TossounianDenes S KovacsTran T ThuBenoit StijlemansDidier VertommenJarne PauwelsKris GevaertGeert AngenonJoris Messens et al.

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Development and characterization of protein kinase B/AKT isoform-specific nanobodies

Tijs MerckaertOlivier ZwaenepoelKris GevaertJan Gettemans

A1 Journal Article in PLOS ONE

FRS7 and FRS12 recruit NINJA to regulate expression of glucosinolate biosynthesis genes

Patricia Fernandez CalvoSabrina IñigoGaétan GlauserRobin Vanden BosscheMichelle TangBaohua LiRebecca De ClercqAstrid Nagels DurandDominique EeckhoutKris Gevaert et al.

A1 Journal Article in NEW PHYTOLOGIST

Food allergen detection : well-defined test materials and accurate peptide biomarkers for development of a mass spectrometry-based detection and quantification method

Kaatje Van VlierbergheKris GevaertChristof Van Poucke

High-resolution mass spectrometry-based selection of peanut peptide biomarkers considering food processing and market type variation

Maxime GavageKaatje Van VlierbergheChristof Van PouckeMarc De LooseKris GevaertMarc DieuPatsy RenardThierry ArnouldNathalie Gillard

A1 Journal Article in FOOD CHEMISTRY

Improved glucocorticoid receptor ligands : fantastic beasts, but how to find them?

Laura Van MoortelKris GevaertKarolien De Bosscher

A1 Journal Article in FRONTIERS IN ENDOCRINOLOGY

Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1

Jasmine BarraGabriel S. GaidoshEzra BlumenthalFelipe BeckedorffMina M. TayariNina KirsteinTobias K. KarakachTorben Heick JensenFrancis ImpensKris Gevaert et al.

A1 Journal Article in SCIENCE ADVANCES

Listeria monocytogenes impairs SUMOylation for efficient infection (vol 464, pg 1192, 2010)

D RibetM HamonE GouinMA NahoriFrancis ImpensH Neyret-KahnKris GevaertJoël VandekerckhoveA DejeanP Cossart

MSqRob takes the missing hurdle : uniting intensity- and count-based proteomics

Ludger GoeminneAdriaan StickerLennart MartensKris GevaertLieven Clement

A1 Journal Article in ANALYTICAL CHEMISTRY

Method optimization for unveiling the proteome landscape of bacterial pathogens in the context of the infected host

Ursula FelsPetra Van DammeKris Gevaert

Mutations in the ubiquitin ligase adaptor LZTR1 drive human disease by dysregulating RAS ubiquitination and signaling.

Mikhail SteklovSilvia PandolfiMaria Francesca BaiettiPaolo CaraiMingzhen ZhangHyunbum JangYanyan CaiEric LegiusJan TavernierKris Gevaert et al.

N-glycosylation site analysis reveals sex-related differences in protein N-glycosylation in the rice brown planthopper (Nilaparvata lugens)

Freja ScheysEls Van DammeJarne PauwelsAn StaesKris GevaertGuy Smagghe

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

N-terminal proteoforms in human disease

Annelies BogaertMaria Fernandez FernandezKris Gevaert

A1 Journal Article in TRENDS IN BIOCHEMICAL SCIENCES

Protein amino-termini and how to identify them

Annelies BogaertKris Gevaert

A1 Journal Article in EXPERT REVIEW OF PROTEOMICS

Regulation of protein abundance by internal and external stimuli in Arabidopsis

Shanshuo ZhuIve De SmetKris Gevaert

Selection of universal peptide biomarkers for the detection of the allergen hazelnut in food trough a comprehensive, high resolution mass spectrometric (HRMS) based approach

Kaatje Van VlierbergheMaxime GavageMarc DieuPatsy RenardThierry ArnouldNathalie GillardKatleen CoudijzerMarc De LooseKris GevaertChristof Van Poucke

A1 Journal Article in FOOD CHEMISTRY

Simple peptide quantification approach for MS-based proteomics quality control

Teresa MaiaAn StaesKim PlasmanJarne PauwelsKatie BoucherAndrea ArgentiniLennart MartensTony MontoyeKris GevaertFrancis Impens

A1 Journal Article in ACS OMEGA

SnRK2 protein kinases and mRNA decapping machinery control root development and response to salt

Dorota KawaA Jessica MeyerHenk L DekkerAhmed Abd-El-HaliemKris GevaertEveline Van De SlijkeJustyna MaszkowskaMaria BucholcGrazyna DobrowolskaGeert De Jaeger et al.

A1 Journal Article in PLANT PHYSIOLOGY

The CEP5 peptide promotes abiotic stress tolerance, as revealed by quantitative proteomics, and attenuates the AUX/IAA equilibrium in Arabidopsis

Stephanie SmithShanshuo ZhuLisa JoosIanto RobertsNatalia NikonorovaLam Dai VuElisabeth StesHyunwoo ChoAntoine LarrieuWei Xuan et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Towards SERS-based multiplexed monitoring of protease activity using non-natural aromatic amino acids

Nina TurkHans DemolAndre SkirtachRoel BaetsKris Gevaert

UBP12 and UBP13 negatively regulate the activity of the ubiquitin-dependent peptidases DA1, DAR1 and DAR2

Hannes VanhaerenYing ChenMattias VermeerschLiesbeth De MildeValerie De VleeschhauwerAnnelore NatranGeert PersiauDominique EeckhoutGeert De JaegerKris Gevaert et al.

A1 Journal Article in eLife

Waveguide-based detection of protease activity using surface-enhanced Raman spectroscopy

Nina TurkAli RazaPieter WuytensHans DemolMichiel Van DaeleChristophe DetavernierAndre SkirtachKris GevaertRoel Baets

Waveguide-based surface-enhanced Raman spectroscopy detection of protease activity using non-natural aromatic amino acids

Nina TurkAli RazaPieter WuytensHans DemolMichiel Van DaeleChristophe DetavernierAndre SkirtachKris GevaertRoel Baets

A1 Journal Article in BIOMEDICAL OPTICS EXPRESS

Waveguide-based surface-enhanced Raman spectroscopy for protease activity detection

Nina TurkRoel BaetsKris Gevaert

2019

A well-controlled BioID design for endogenous bait proteins

Giel VandemoorteleDelphine De SutterAline MoliereJarne PauwelsKris GevaertSven Eyckerman

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

CYP707As are effectors of karrikin and strigolactone signalling pathways in Arabidopsis thaliana and parasitic plants

Guillaume BrunSéverine ThoironLukas BraemJean‐Bernard PouvreauGrégory MonatielMarc‐Marie LechatPhilippe SimierKris GevaertSofie GoormachtigPhilippe Delavault

A1 Journal Article in PLANT CELL AND ENVIRONMENT

Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase

Jelle Van LeeneChao HanAstrid GadeyneDominique EeckhoutCaroline MatthijsBernard CannootNancy De WinneGeert PersiauEveline Van De SlijkeBrigitte Van De Cotte et al.

A1 Journal Article in NATURE PLANTS

Caught green-handed : methods for in vivo detection and visualization of protease activity

Álvaro Daniel Fernández FernándezRenier AL van der HoornKris GevaertFrank Van BreusegemSimon Stael

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

Characterization of the γ-secretase subunit interactome in Arabidopsis thaliana

Tomasz SkrzypczakRafal KrelaShraddha WadurkarKris GevaertEveline Van De SlijkeGeert De JaegerKrzysztof LesniewiczPrzemyslaw Wojtaszek

A1 Journal Article in ACTA PHYSIOLOGIAE PLANTARUM

Comparison of free-space and waveguide-based SERS platforms

Nina TurkAli RazaPieter WuytensHans DemolMichiel Van DaeleChristophe DetavernierAndre SkirtachKris GevaertRoel Baets

A1 Journal Article in NANOMATERIALS

Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides

Tim HanderÁlvaro Daniel Fernández FernándezRobert KumpfPatrick WillemsHendrik SchatowitzDebbie RombautAn StaesJonah NolfRobin PottiePanfeng Yao et al.

A1 Journal Article in SCIENCE

Design and visualization of second generation cyanoisoindole based fluorescent strigolactone analogs

Melissa Van OvertveldtLukas BraemSylwia Magdalena StrukAnna KaczmarekFrançois‐Didier BoyerRik Van DeunKris GevaertSofie GoormachtigThomas HeugebaertChristian Stevens

A1 Journal Article in PLANT JOURNAL

Developmental plasticity at high temperature

Lam Dai VuXiangyu XuKris GevaertIve De Smet

A1 Journal Article in PLANT PHYSIOLOGY

Disruption of endocytosis through chemical inhibition of clathrin heavy chain function

Wim DejongheIsha SharmaBram DenooSteven De MunckQing LuKiril MishevHaydar BulutEvelien MylleRiet De RyckeMina Vasileva et al.

A1 Journal Article in NATURE CHEMICAL BIOLOGY

Distinct branches of the N-end rule pathway modulate the plant immune response

Jorge VicenteGuillermina M MendiondoJarne PauwelsVictoria PastorYovanny IzquierdoChristin NaumannMahsa MovahediDaniel RooneyDaniel J GibbsKatherine Smart et al.

A1 Journal Article in NEW PHYTOLOGIST

EXPANSIN A1-mediated radial swelling of pericycle cells positions anticlinal cell divisions during lateral root initiation

Priya RamakrishnaPaola Ruiz DuarteGraham A RanceMartin SchubertVera VordermaierLam Dai VuEvan MurphyAmaya Vilches BarroKamal SwarupKamaljit Moirangthem et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring the protein-protein interaction landscape in plants

Sylwia Magdalena StrukAnse JacobsElena Sánchez Martín-FontechaKris GevaertPilar CubasSofie Goormachtig

A1 Journal Article in PLANT CELL AND ENVIRONMENT

Extracellular peptide Kratos restricts cell death during vascular development and stress in Arabidopsis

Sacha EscamezSimon StaelJulia P VainonenPatrick WillemsHuiting JinSachie KimuraFrank Van BreusegemKris GevaertMichael WrzaczekHannele Tuominen

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

Feeling the heat : searching for plant thermosensors

Lam Dai VuKris GevaertIve De Smet

A1 Journal Article in TRENDS IN PLANT SCIENCE

High-throughput proteome analysis using 50 cm long micro pillar arraycolumns (µPAC)

Jeff Op De BeeckGeert Van RaemdonckPaul JacobsGert DesmetWim De MalscheFrancis ImpensKris Gevaert

Hydrogen plasma cleaning of gold plasmonic nanostructures for better reproducibility of SERS spectra

Nina TurkAndre SkirtachKris GevaertRoel Baets

Look closely, the beautiful may be small : precursor-derived peptides in plants

Vilde OlssonLisa JoosShanshuo ZhuKris GevaertMelinka A ButenkoIve De Smet

A1 Journal Article in Annual Review of Plant Biology

Mining for protein S-sulfenylation in Arabidopsis uncovers redox-sensitive sites

Jingjing HuangPatrick WillemsBo WeiCaiping TianRenan B FerreiraNandita BodraSantiago Agustín Martínez GacheKhadija WahniKeke LiuDidier Vertommen et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation mediates high temperature signalling in plants

Lam Dai VuIve De SmetKris Gevaert

Pick a tag and explore the functions of your pet protein

Giel VandemoorteleSven EyckermanKris Gevaert

A1 Journal Article in TRENDS IN BIOTECHNOLOGY

Plant proteases and programmed cell death

Simon StaelFrank Van BreusegemKris GevaertMoritz Nowack

Editorial material

Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection

Jolien Van CleemputKatrien PoelaertKathlyn LavalFrancis ImpensWim Van Den BroeckKris GevaertHans Nauwynck

A1 Journal Article in SCIENTIFIC REPORTS

Salmonella Typhi, Paratyphi A, Enteritidis and Typhimurium core proteomes reveal differentially expressed proteins linked to the cell surface and pathogenicity

Sara SalehSandra Van PuyveldeAn StaesEvy TimmermanBarbara BarbéJan JacobsKris GevaertStijn Deborggraeve

A1 Journal Article in PLOS NEGLECTED TROPICAL DISEASES

Selection of egg peptide biomarkers in processed food products by high resolution mass spectrometry

M GavageKaatje Van VlierbergheC Van PouckeM De LooseKris GevaertM DieuP RenardT ArnouldN Gillard

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Statistical methods for differential proteomics at peptide and protein level

Ludger GoeminneLieven ClementKris Gevaert

Targeted proteomics for studying pathogenic bacteria

Sara SalehAn StaesStijn DeborggraeveKris Gevaert

A1 Journal Article in PROTEOMICS

The Plant PTM Viewer, a central resource for exploring plant protein modifications

Patrick WillemsAlison HorneThomas Van ParysSofie GoormachtigIve De SmetAlexander BotzkiFrank Van BreusegemKris Gevaert

A1 Journal Article in PLANT JOURNAL

The generation and use of recombinant extracellular vesicles as biological reference material

Edward GeeurickxJoeri TulkensBert DhondtJan Van DeunLien LippensGlenn VergauwenElisa HeyrmanDelphine De SutterKris GevaertFrancis Impens et al.

A1 Journal Article in NATURE COMMUNICATIONS

Towards a genome engineering toolbox for proteomics

Giel VandemoorteleSven EyckermanKris Gevaert

2018

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van QuickelbergheDelphine De SutterGeert van LooSven EyckermanKris Gevaert

A1 Journal Article in SCIENTIFIC DATA

Challenges in the structural-functional characterization of multidomain, partially disordered proteins CBP and p300 : preparing native proteins and developing nanobody tools

Angela BekesiSara AbdellaouiNatalie HolroydWouter Van DelmEls PardonJarne PauwelsKris GevaertJan SteyaertStefaan DerveauxAntoni Borysik et al.

A1 Journal Article in Methods in Enzymology

Chronic kidney disease circulating calciprotein particles and extracellular vesicles promote vascular calcification : a role for GRP (Gla-rich protein)

Carla SB ViegasLúcia SantosAnjos L MacedoAntónio A MatosAna P SilvaPedro L NevesAn StaesKris GevaertRute MoraisCees Vermeer et al.

A1 Journal Article in ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis

Amr NassrallahMartin RougéeClara BourbousseStephanie DrevensekSandra FonsecaElisa IniestoOuardia Ait-MohamedAnne-Flore Deton-CabanillasGerald ZabulonIkhlak Ahmed et al.

A1 Journal Article in ELIFE

Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage

Maria-Armineh TossounianInge Van MolleKhadija WahniSilke JacquesKris GevaertFrank Van BreusegemDidier VertommenDavid YoungLeonardo Astolfi RosadoJoris Messens

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Early mannitol-triggered changes in the Arabidopsis leaf (phospho) proteome reveal growth regulators

Natalia NikonorovaLisa Van den BroeckShanshuo ZhuBrigitte Van De CotteMarieke DuboisKris GevaertDirk InzéIve De Smet

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

Evolutionarily conserved and species-specific glycoproteins in the N-glycoproteomes of diverse insect species

Freja ScheysEls Van DammeKristof De SchutterAn StaesKris GevaertGuy Smagghe

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Experimental design and data-analysis in label-free quantitative LC/MS proteomics : a tutorial with MSqRob

Ludger GoeminneKris GevaertLieven Clement

A1 Journal Article in JOURNAL OF PROTEOMICS

FIGL1 and its novel partner FLIP form a conserved complex that regulates homologous recombination

Joiselle Blanche FernandesMarine DuhamelMathilde Seguéla-ArnaudNicole FrogerChloé GirardSandrine ChoinardVictor SolierNancy De WinneGeert De JaegerKris Gevaert et al.

A1 Journal Article in PLOS GENETICS

GSyellow, a multifaceted tag for functional protein analysis in monocot and dicot plants

Nienke BesbruggeJelle Van LeeneDominique EeckhoutBernard CannootShubhada Rajabhau KulkarniNancy De WinneGeert PersiauEveline Van De SlijkeMichiel BontinckStijn Aesaert et al.

A1 Journal Article in PLANT PHYSIOLOGY

Identification of immune-responsive gene 1 (IRG1) as a target of A20

Emmy Van QuickelbergheArne MartensLudger GoeminneLieven ClementGeert van LooKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Impairment of angiogenesis by fatty acid synthase inhibition involves mTOR malonylation

Ulrike BruningFrancisco Morales-RodriguezJoanna KaluckaJermaine GoveiaFederico TavernaKarla CS QueirozCharlotte DuboisAnna Rita CantelmoRongyuan ChenStefan Loroch et al.

A1 Journal Article in CELL METABOLISM

Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination

M SteklovS PandolfiMF BaiettiA BatiukP CaraiP NajmM ZhangH JangF RenziY Cai et al.

A1 Journal Article in SCIENCE

N-terminal acetylation levels are maintained during acetyl-CoA deficiency in Saccharomyces cerevisiae

Sylvia VarlandHenriette AksnesFedor KryuchkovFrancis ImpensDelphi Van HaverVeronique JonckheereMathias ZieglerKris GevaertPetra Van DammeThomas Arnesen

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

NAA80 is actin’s N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility

Adrian DrazicHenriette AksnesMichaël MarieMalgorzata BoczkowskaSylvia VarlandEvy TimmermanHåvard FoynNina GlomnesGrzegorz RebowskiFrancis Impens et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organellar omics : a reviving strategy to untangle the biomolecular complexity of the cell

Arun Kumar Tharkeshwar RaghunathKris GevaertWim Mannaerts

A1 Journal Article in PROTEOMICS

Peanut stunt virus and its satellite RNA trigger changes in phosphorylation in N-benthamiana infected plants at the early stage of the infection

Barbara WrzesinskaLam Dai VuKris GevaertIve De SmetAleksandra Obrepalska-Steplowska

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Plant redox biology with an -omics perspective

Patrick WillemsFrank Van BreusegemKris Gevaert

Protein language : post-translational modifications talking to each other

Lam Dai VuKris GevaertIve De Smet

A1 Journal Article in TRENDS IN PLANT SCIENCE

Proteome analysis of Arabidopsis roots

Natalia NikonorovaLam Dai VuElisabeth StesKris GevaertIve De Smet

Bookchapter in Root development : methods and protocols

Quantitative proteomics and systems analysis of cultured H9C2 cardiomyoblasts during differentiation over time supports a ‘function follows form’ model of differentiation

Cynthia KankeuKylie ClarkeDelphi Van HaverKris GevaertFrancis ImpensAnna DittrichH Llewelyn RoderickEgle PassanteHeinrich J Huber

A1 Journal Article in MOLECULAR OMICS

Quantitative tandem affinity purification, an effective tool to investigate protein complex composition in plant hormone signaling : strigolactones in the spotlight

Sylwia Magdalena StrukLukas BraemAlan WaltonAnnick De KeyserFrançois-Didier BoyerGeert PersiauGeert De JaegerKris GevaertSofie Goormachtig

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

RIPK4 activity in keratinocytes is controlled by the SCFβ-TrCP ubiquitin ligase to maintain cortical actin organization

Giel TangheCorinne UrwylerPhilippe De GrooteEmmanuel DejardinPieter-Jan De BockKris GevaertPeter VandenabeeleWim Declercq

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxElisa HeyrmanJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensIlkka Miinalainen et al.

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxElisa HeyrmanJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensIlkka Miinalainen et al.

Seed germination in parasitic plants : what insights can we expect from strigolactone research?

Guillaume BrunLukas BraemSeverine ThoironKris GevaertSofie GoormachtigPhilippe Delavault

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

Studying the double-faced A20 protein by contemporary proteomics

Emmy Van QuickelbergheKris GevaertGeert van Loo

Synaptogyrin-3 mediates presynaptic dysfunction induced by Tau

Joseph McInnesKeimpe WierdaAn SnellinxLaura BountiYu-Chun WangIlie-Cosmin StancuNuno ApóstoloKris GevaertIlse DewachterTara L Spires-Jones et al.

A1 Journal Article in NEURON

Temperature-induced changes in the wheat phosphoproteome reveal temperature-regulated interconversion of phosphoforms

Lam Dai VuTingting ZhuInge VerstraetenBrigitte Van De CotteKris GevaertIve De Smet

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages

Viacheslav MylkaJulie DeckersDariusz RatmanLode De CauwerJonathan ThommisRiet De RyckeFrancis ImpensClaude LibertJan TavernierWim Vanden Berghe et al.

A1 Journal Article in AUTOPHAGY

Towards SERS-based on-chip detection of protease activity using nanoplasmonic slot waveguides

Nina TurkAli RazaPieter WuytensHans DemolAndre SkirtachKris GevaertRoel Baets

Towards mulitplexed SERS-based on-chip detection on protease activity

Nina TurkPieter WuytensHans DemolKris GevaertAndre SkirtachMohamed LamkanfiRoel Baets

2017

A leap over the hurdle in label-free quantitative proteomics

Ludger GoeminneKris GevaertLieven Clement

A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics : the case of NPC1 deficiency

Arun Kumar Tharkeshwar RaghunathJesse TrekkerWendy VermeireJarne PauwelsRagna SannerudDavid A PriestmanDanielle te VruchteKatlijn VintsPieter BaatsenJean-Paul Decuypere et al.

A1 Journal Article in SCIENTIFIC REPORTS

Analyzing repeated measures designs in label-free proteomics with MSqRob (MCP 2016 15(2):657-68.)

Lieven ClementLudger GoeminneEmmy Van QuickelbergheKris Gevaert

Analyzing trapped protein complexes by Virotrap and SFINX

Kevin TitecaEmmy Van QuickelbergheNoortje SamynDelphine De SutterAnnick VerheeKris GevaertJan TavernierSven Eyckerman

A1 Journal Article in NATURE PROTOCOLS

Confounding factors in extracellular vesicle ultrafiltration and protein analysis

Glenn VergauwenBert DhondtJan Van DeunEvy TimmermanKris GevaertGeert BraemsRudy Van den BroeckeVeronique CocquytHannelore DenysOlivier De Wever et al.

Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research

Glenn VergauwenBert DhondtJan Van DeunEva De SmedtGeert BerxEvy TimmermanKris GevaertIlkka MiinalainenVeronique CocquytGeert Braems et al.

A1 Journal Article in SCIENTIFIC REPORTS

Deregulation of focal adhesion formation and cytoskeletal tension due to loss of A-type lamins

Tobias CorneTom SieprathJonathan VandenbusscheDanahe MohammedMariska te LindertKris GevaertSylvain GabrieleKatarina WolfWinnok De Vos

A1 Journal Article in CELL ADHESION & MIGRATION

Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors

Dennis PlenkerMaximilian RiedelJohannes BrägelmannMarcel A DammertRakhee ChauhanPhillip P KnowlesCarina LorenzMarina KeulMike BührmannOliver Pagel et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

Ectopic application of the repressive histone modification H3K9me2 establishes post-zygotic reproductive isolation in Arabidopsis thaliana

Hua JiangJordi Moreno-RomeroJuan Santos-GonzalezGeert De JaegerKris GevaertEveline Van De SlijkeClaudia Kohler

A1 Journal Article in GENES & DEVELOPMENT

Expanding the interactome of TES by exploiting TES modules with different subcellular localizations

Stefano SalaMarleen Van TroysSandrine MedvesMarie CatillonEvy TimmermanAn StaesElisabeth Schaffner-ReckingerKris GevaertChristophe Ampe

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Gold nanodome SERS platform for label-free detection of protease activity

Pieter WuytensHans DemolNina TurkKris GevaertAndre SkirtachMohamed LamkanfiRoel Baets

A1 Journal Article in FARADAY DISCUSSIONS

Identification of carboxypeptidase substrates by C-terminal COFRADIC

Sebastian TancoFrancesc Xavier AvilesKris GevaertJulia LorenzoPetra Van Damme

Bookchapter in Protein terminal profiling : methods and protocols

Identification of confounding factors of EV isolation and protein analysis

Glenn VergauwenBert DhondtJan Van DeunEvy TimmermanKris GevaertVeronique CocquytGeert BraemsRudy Van den BroeckeHannelore DenysOlivier De Wever et al.

Linking functions : an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP

Sara Contreras-MartosAlessandro PiaiSimone KosolMihaly VaradiAngela BekesiPierre LebrunAlexander N VolkovKris GevaertRoberta PierattelliIsabella C Felli et al.

A1 Journal Article in SCIENTIFIC REPORTS

MSqRob : analysis of label-free proteomics data in an R/Shiny environment

Ludger GoeminneKris GevaertLieven Clement

MSqRob: analysis of label-free proteomics data in an R/Shiny environment

Ludger GoeminneEmmy Van QuickelbergheKris GevaertLieven Clement

N-terminal proteomics assisted profiling of the unexplored translation initiation landscape in Arabidopsis thaliana

Patrick WillemsElvis NdahVeronique JonckheereSimon StaelAdriaan StickerLennart MartensFrank Van BreusegemKris GevaertPetra Van Damme

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Noncoding after all : biases in proteomics data do not explain observed absence of lncRNA translation products

Kenneth VerheggenPieter-Jan VoldersPieter MestdaghGerben MenschaertPetra Van DammeKris GevaertLennart MartensJo Vandesompele

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Novel insights into the choroid plexus' response to systemic inflammation and Alzheimer's disease

Sriram BalusuRoosmarijn VandenbrouckeClaude LibertKris Gevaert

Protease substrate profiling by N-terminal COFRADIC

An StaesPetra Van DammeEvy TimmermanBart RuttensElisabeth StesKris GevaertFrancis Impens

Bookchapter in Protein terminal profiling : methods and protocols

Proteogenomics in aid of host-pathogen interaction studies : a bacterial perspective

Ursula FelsKris GevaertPetra Van Damme

A2 Journal Article in PROTEOMES

Proteome profiling of wheat shoots from different cultivars

Lam Dai VuInge VerstraetenElisabeth StesMichiel Van BelFrederik CoppensKris GevaertIve De Smet

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma

Bieke DecaestekerSara De BrouwerFanny De VloedGeertrui DeneckerSuzanne VanhauwaertJolien De WynGenevieve LaureysBjörn MentenPauline DepuydtPatrick Reynolds et al.

SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma

Bieke DecaestekerSara De BrouwerFanny De VloedGeertrui DeneckerSuzanne VanhauwaertJolien De WynGenevieve LaureysBjörn MentenPauline DepuydtJo Vandorpe et al.

Selective glucocorticoid receptor properties of GSK866 analogs with cysteine reactive warheads

Chandra S ChirumamillaAjay PalaganiBalu KamarajKen DeclerckMarinus WC VerbeekOksana RyabtsovaKarolien De BosscherNadia BougarneBart RuttensKris Gevaert et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Strigolactones, karrikins and beyond

Carolien De CuyperSylwia Magdalena StrukLukas BraemKris GevaertGeert De JaegerSofie Goormachtig

A1 Journal Article in PLANT CELL AND ENVIRONMENT

The mTOR and PP2A pathways regulate PHD2 phosphorylation to fine-tune HIF1α levels and colorectal cancer cell survival under hypoxia

Giusy Di ConzaSarah Trusso CafarelloStefan LorochDaniela MennerichSofie DeschoemaekerMario Di MatteoManuel EhlingKris GevaertHans PrenenRene Peiman Zahedi et al.

A1 Journal Article in CELL REPORTS

The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis

Andrés Ritter TraubSabrina IñigoPatricia Fernandez CalvoKen HeyndrickxStijn DhondtHua ShiLiesbeth De MildeRobin Vanden BosscheRebecca De ClercqDominique Eeckhout et al.

A1 Journal Article in NATURE COMMUNICATIONS

2016

A role for human N-alpha acetyltransferase 30 (Naa30) in maintaining mitochondrial integrity

Petra Van DammeThomas V KalvikKristian W StarheimVeronique JonckheereLine M MyklebustGerben MenschaertJan Erik VarhaugKris GevaertThomas Arnesen

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

ADAM30 downregulates APP-linked defects through cathepsin D activation in Alzheimer's disease

Florent LetronneGeoffroy LaumetAnne-Marie AyralJulien ChapuisFlorie DemiautteMathias LagaMichel E VandenbergheNicolas MalmancheFlorence LerouxFanny Eysert et al.

A1 Journal Article in EBIOMEDICINE

Alternative translation initiation unraveled by N-terminomics and ribosome profiling

Daria FijalkowskaPetra Van DammeKris Gevaert

An extra dimension in protein tagging by quantifying universal proteotypic peptides using targeted proteomics

Giel VandemoorteleAn StaesGiulia GonnelliNoortje SamynDelphine De SutterElien VandermarliereEvy TimmermanKris GevaertLennart MartensSven Eyckerman

A1 Journal Article in SCIENTIFIC REPORTS

An omics strategy to unravel the role of the β2-adrenergic receptor in inflammation

Sarah GerloGuy LaureysKrzysztof KolmusSven EyckermanKris GevaertIrma LemmensJan Tavernier

CEP5 and XIP1/CEPR1 regulate lateral root initiation in Arabidopsis

Ianto RobertsStephanie SmithElisabeth StesBert De RybelAn StaesBrigitte Van De CotteMaria NjoLise DedeyneHans DemolJulien Lavenus et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

Construction and analysis of a human testis/sperm-enriched interaction network : unraveling the PPP1CC2 interactome

Joana Vieira SilvaSooyeon YoonPieter-Jan De BockAlexander V GoltsevKris GevaertJosé Fernando F MendesMargarida Fardilha

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

De novo design of a biologically active amyloid

Rodrigo GallardoMeine RamakersFrederik De SmetFilip ClaesLadan KhodaparastLaleh KhodaparastJosé R CouceiroTobias LangenbergMaxime SiemonsSofie Nyström et al.

A1 Journal Article in SCIENCE

Diagonal chromatography to study plant protein modifications

Alan WaltonStyliani TsiatsianiSilke JacquesElisabeth StesJoris MessensFrank Van BreusegemSofie GoormachtigKris Gevaert

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

FYVE1/FREE1 interacts with the PYL4 ABA receptor and mediates its delivery to the vacuolar degradation pathway

Borja Belda-PalazonLesia RodriguezMaria A FernandezMari-Cruz CastilloErin M AndersonCaiji GaoMiguel Gonzalez-GuzmanMarta Peirats-LlobetQiong ZhaoNancy De Winne et al.

A1 Journal Article in PLANT CELL

Functional characterization of inflammatory caspases

Daniel Jiménez FernandezMohamed LamkanfiKris Gevaert

Functional characterization of the Arabidopsis transcription factor bZIP29 reveals its role in leaf and root development

Jelle Van LeeneJonas BlommeShubhada Rajabhau KulkarniBernard CannootNancy De WinneDominique EeckhoutGeert PersiauEveline Van De SlijkeLeen VercruysseRobin Vanden Bossche et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes

James DooleyLei TianSusann SchonefeldtViviane Delghingaro-AugustoJosselyn E Garcia-PerezEmanuela PasciutoDaniele Di MarinoEdward J CarrNikolay OskolkovValeriya Lyssenko et al.

A1 Journal Article in NATURE GENETICS

Glutaredoxin GRXS17 associates with the cytosolic iron-sulfur cluster assembly pathway

Sabrina IñigoAstrid Nagels DurandAndrés Ritter TraubSabine Le GallMartin TermatheRoland KlassenTakayuki TohgeBarbara De ConinckJelle Van LeeneRebecca De Clercq et al.

A1 Journal Article in PLANT PHYSIOLOGY

HIV-1 Vpr N-terminal tagging affects alternative splicing of the viral genome

Ann BaeyensEvelien NaessensAnouk Van NuffelKarin WeeningAnne-Marie ReillyEva ClaeysWim TrypsteenLinos VandekerckhoveSven EyckermanKris Gevaert et al.

A1 Journal Article in SCIENTIFIC REPORTS

Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles

Sriram BalusuElien Van WonterghemRiet De RyckeKoen RaemdonckStephan StremerschKris GevaertMarjana BrkicDelphine DemeestereValerie VanhoorenAn Hendrix et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

Intelligent mixing of proteomes for elimination of false positives in affinity purification-mass spectrometry

Sven EyckermanFrancis ImpensEmmy Van QuickelbergheNoortje SamynGiel VandemoorteleDelphine De SutterJan TavernierKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Isolation of protein complexes from the model legume Medicago truncatula by tandem affinity purification in hairy root cultures

Jonas GoossensNathan De GeyterAlan WaltonDominique EeckhoutJan MertensJacob PollierJennifer Liliana Fiallos JuradoAnnick De KeyserRebecca De ClercqJelle Van Leene et al.

A1 Journal Article in PLANT JOURNAL

It's time for some 'site'-seeing: novel tools to monitor the ubiquitin landscape in Arabidopsis thaliana

Alan WaltonElisabeth StesNicolas CybulskiMichiel Van BelSabrina IñigoAstrid Nagels DurandEvy TimmermanJefri HeymanLaurens PauwelsLieven De Veylder et al.

A1 Journal Article in PLANT CELL

Melanoma addiction to the long non-coding RNA SAMMSON

Eleonora LeucciRoberto VendraminMarco SpinazziPatrick LauretteMark FiersJasper WoutersEnrico RadaelliSven EyckermanCarina LeonelliKatrien Vanderheyden et al.

A1 Journal Article in NATURE

PP2A-3 interacts with ACR4 and regulates formative cell division in the Arabidopsis root

Kun YuePriyanka SandalElisabeth L. WilliamsEvan MurphyElisabeth StesNatalia NikonorovaPriya RamakrishnaNathan CzyzewiczLaura Montero MoralesRobert Kumpf et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptide-level robust ridge regression improves estimation, sensitivity, and specificity in data-dependent quantitative label-free shotgun proteomics

Ludger GoeminneKris GevaertLieven Clement

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Positional proteomics reveals differences in N-terminal proteoform stability

Daria FijalkowskaElvis NdahKris GevaertPetra Van Damme

A1 Journal Article in MOLECULAR SYSTEMS BIOLOGY

Protein aggregation as an antibiotic design strategy

Natalia G BednarskaJohan van EldereRodrigo GallardoAshok GanesanMeine RamakersIsabel VogelPieter BaatsenAn StaesMarc GoethalsPer Hammarström et al.

A1 Journal Article in MOLECULAR MICROBIOLOGY

Proteomics in the genome engineering era

Giel VandemoorteleKris GevaertSven Eyckerman

A1 Journal Article in PROTEOMICS

Resolution of protein structure by mass spectrometry

Elien VandermarliereElisabeth StesKris GevaertLennart Martens

A1 Journal Article in MASS SPECTROMETRY REVIEWS

SFINX : straightforward filtering index for affinity purification mass spectrometry data analysis

Kevin TitecaPieter MeysmanKris GevaertJan TavernierKris LaukensLennart MartensSven Eyckerman

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Strigolactone signaling through the eye of the mass spectrometer

Alan WaltonSofie GoormachtigKris Gevaert

Superparamagnetic nanoparticle based isolation of subcellular compartments as a method to identify spatial alterations in protein and lipid composition

Arun Kumar Tharkeshwar RaghunathWim AnnaertKris GevaertLiesbet Lagae

The Arabidopsis iron-sulfur protein GRXS17 is a target of the ubiquitin E3 ligases RGLG3 and RGLG4

Astrid Nagels DurandSabrina IñigoAndrés Ritter TraubElisa IniestoRebecca De ClercqAn StaesJelle Van LeeneVicente RubioKris GevaertGeert De Jaeger et al.

A1 Journal Article in PLANT AND CELL PHYSIOLOGY

The ROS wheel: refining ROS transcriptional footprints

Patrick WillemsAmna M'HamdiSimon StaelVeronique StormePavel KerchevGraham NoctorKris GevaertFrank Van Breusegem

A1 Journal Article in PLANT PHYSIOLOGY

The growing story of (ARABIDOPSIS) CRINKLY 4

Nathan CzyzewiczNatalia NikonorovaMatthew R MeyerPriyanka SandalShweta ShahLam Dai VuKris GevaertA Gururaj RaoIve De Smet

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

The response of the root proteome to the synthetic strigolactone GR24 in Arabidopsis

Alan WaltonElisabeth StesGeert GoeminneLukas BraemMarnik VuylstekeCedrick MatthysCarolien De CuyperAn StaesJonathan VandenbusscheFrançois-Didier Boyer et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

The whats, the wheres and the hows of strigolactone action in the roots

Cedrick MatthysAlan WaltonSylwia Magdalena StrukElisabeth StesFrançois-Didier BoyerKris GevaertSofie Goormachtig

A1 Journal Article in PLANTA

Transferring an optimized TAP-toolbox for the isolation of protein complexes to a portfolio of rice tissues

Maarten DedeckerJelle Van LeeneNancy De WinneDominique EeckhoutGeert PersiauEveline Van De SlijkeBernard CannootLeen VercruysseLies DumoulinNathalie Wojsznis et al.

A1 Journal Article in PLANT MOLECULAR BIOLOGY

Trapping mammalian protein complexes in viral particles

Sven EyckermanKevin TitecaEmmy Van QuickelbergheEva ClootsAnnick VerheeNoortje SamynLeentje De CeuninckEvy TimmermanDelphine De SutterSam Lievens et al.

A1 Journal Article in NATURE COMMUNICATIONS

Up-to-date workflow for plant (phospho)proteomics identifies differential drought-responsive phosphorylation events in maize leaves

Lam Dai VuElisabeth StesMichiel Van BelHilde NelissenDavy MaddeleinDirk InzéFrederik CoppensLennart MartensKris GevaertIve De Smet

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Xilmass: a new approach toward the identification of cross-linked peptides

Sule Yilmaz-RumpfFriedel DrepperNiels HulstaertMaša ČerničKris GevaertAnastassios EconomouBettina WarscheidLennart MartensElien Vandermarliere

A1 Journal Article in ANALYTICAL CHEMISTRY

Zebrafish collagen type I: molecular and biochemical characterization of the major structural protein in bone and skin

Charlotte GistelinckR GioiaA GagliardiF TonelliL MarcheseL BianchiC LandiL BiniAnn HuysseunePaul Witten et al.

A1 Journal Article in SCIENTIFIC REPORTS

2015

A multi-angled view on oxidative stress in A. thaliana leaves : filling the gaps

Silke JacquesFrank Van BreusegemKris Gevaert

A phylogenetic approach to study the origin and evolution of the CRINKLY4 family

Natalia NikonorovaLam Dai VuNathan CzyzewiczKris GevaertIve De Smet

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

A repressor protein complex regulates leaf growth in Arabidopsis

Nathalie Gonzalez SanchezLaurens PauwelsAlexandra BaekelandtLiesbeth De MildeJelle Van LeeneNienke BesbruggeKen HeyndrickxAmparo Cuéllar PérezAstrid Nagels DurandRebecca De Clercq et al.

A1 Journal Article in PLANT CELL

An improved toolbox to unravel the plant cellular machinery by tandem affinity purification of Arabidopsis protein complexes

Jelle Van LeeneDominique EeckhoutBernard CannootNancy De WinneGeert PersiauEveline Van De SlijkeLeen VercruysseMaarten DedeckerAurine VerkestKlaas Vandepoele et al.

A1 Journal Article in NATURE PROTOCOLS

An organellar Nα-acetyltransferase, Naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity

Henriette AksnesPetra Van DammeMarianne GorisKristian K StarheimMichaël MarieSvein Isungset StøveCamilla HoelThomas Vikestad KalvikKristine HoleNina Glomnes et al.

A1 Journal Article in CELL REPORTS

Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects

Line M MyklebustPetra Van DammeSvein I StøveMax J DörfelAngèle AbboudThomas V KalvikCedric GrauffelVeronique JonckheereYiyang WuJeffrey Swensen et al.

A1 Journal Article in HUMAN MOLECULAR GENETICS

C-terminomics screen for natural substrates of cytosolic carboxypeptidase 1 reveals processing of acidic protein C termini

Sebastian TancoOlivia TortHans DemolFrancesc Xavier AvilesKris GevaertPetra Van DammeJulia Lorenzo

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

C-terminomics: targeted analysis of natural and posttranslationally modified protein and peptide C-termini

Sebastian TancoKris GevaertPetra Van Damme

A1 Journal Article in PROTEOMICS

Cysteines under ROS attack in plants : a proteomics view

Mosammat Salma AkterJingjing HuangCezary WaszczakSilke JacquesKris GevaertFrank Van BreusegemJoris Messens

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

DYn-2 based identification of Arabidopsis sulfenomes

Mosammat Salma AkterJingjing HuangNandita BodraBarbara De SmetKhadija WahniDebbie RombautJarne PauwelsKris GevaertKate CarrollFrank Van Breusegem et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Dynamic changes in ANGUSTIFOLIA3 complex composition reveal a growth regulatory mechanism in the maize leaf

Hilde NelissenDominique EeckhoutKirin DemuynckGeert PersiauAlan WaltonMichiel Van BelMarieke VervoortJasper CandaeleJolien De BlockStijn Aesaert et al.

A1 Journal Article in PLANT CELL

Exploring lncRNAs in cancer : tools for discovery and characterization of cancer associated lncRNAs

Pieter-Jan VoldersJo VandesompeleKris Gevaert

Fast profiling of protease specificity reveals similar substrate specificities for cathepsins K, L and S

Matej VizovišekRobert VidmarEmmy Van QuickelbergheFrancis ImpensUroš AndjelkovićBarbara SobotičVeronika StokaKris GevaertBoris TurkMarko Fonović

A1 Journal Article in PROTEOMICS

GRIM REAPER peptide binds to receptor kinase PRK5 to trigger cell death in Arabidopsis

Michael WrzaczekJulia P VainonenSimon StaelStyliani TsiatsianiHanna Help-Rinta-RahkoAdrien GauthierDavid KaufholdtBenjamin BollhönerAiri LamminmäkiAn Staes et al.

A1 Journal Article in EMBO JOURNAL

LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism

Amaia M ArranzLore DelbroekKristof Van KolenMarco R GuimarãesWim MandemakersGuy DaneelsSamer MattaSara CalafateHamdy ShabanPieter Baatsen et al.

A1 Journal Article in JOURNAL OF CELL SCIENCE

Limited proteolysis combined with stable isotope labeling reveals conformational changes in protein (pseudo)kinases upon binding small molecules

Michela Di MicheleElisabeth StesElien VandermarliereRohit AroraJuan Astorga-WellsJonathan VandenbusscheErika van HeerdeRoman ZubarevPascal BonnetJoannes TM Linders et al.

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Metabolic regulation of N-terminal acetylation in Saccharomyces cerevisiae

Sylvia VarlandPetra Van DammeJolien HollebekeHenriette AksnesKris GevaertThomas Arnesen

Multiple mechanisms limit meiotic crossovers: TOP3 alpha and two BLM homologs antagonize crossovers in parallel to FANCM

Mathilde Séguéla-ArnaudWayne CrismaniCécile LarchevêqueJulien MazelNicole FrogerSandrine ChoinardAfef LemhemdiNicolas MacaisneJelle Van LeeneKris Gevaert et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N-terminal acetylome analysis reveals the specificity of Naa50 (Nat5) and suggests a kinetic competition between N-terminal acetyltransferases and methionine aminopeptidases

Petra Van DammeKristine HoleKris GevaertThomas Arnesen

A1 Journal Article in PROTEOMICS

NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest

Vanessa AndriesKarl VandepoeleKatrien StaesGeert BerxPieter BogaertGert Van IsterdaelDaisy GinnebergeEef ParthoensJonathan VandenbusscheKris Gevaert et al.

A1 Journal Article in BMC CANCER

OMICS views on protein N-terminal biology

Petra Van DammeKris Gevaert

Editorial material

PepShell : visualization of conformational proteomics data

Elien VandermarliereDavy MaddeleinNiels HulstaertElisabeth StesMichela Di MicheleKris GevaertEdgar JacobyDirk BrehmerLennart Martens

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Peptide-level robust ridge regression modeling improves both sensitivity and specificity in quantitative proteomics

Ludger GoeminneLieven ClementKris GevaertKlaas Vandepoele

Phosphoproteomics-based peptide ligand-receptor kinase pairing: commentary on: 'A peptide hormone and its receptor protein kinase regulate plant cell expansion'

Elisabeth StesKris GevaertIve De Smet

Editorial material

Plant hormone signalling through the eye of the mass spectrometer

Alan WaltonElisabeth StesIve De SmetSofie GoormachtigKris Gevaert

A1 Journal Article in PROTEOMICS

Protein methionine sulfoxide dynamics in Arabidopsis thaliana under oxidative stress

Silke JacquesBart GhesquièrePieter-Jan De BockHans DemolKhadija WahniPatrick WillemsJoris MessensFrank Van BreusegemKris Gevaert

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Proteomic approaches to identify substrates of the three Deg/HtrA proteases of the cyanobacterium Synechocystis sp PCC 6803

Lam X TamHarald AignerEvy TimmermanKris GevaertChristiane Funk

A1 Journal Article in BIOCHEMICAL JOURNAL

Proteomic identification of cysteine cathepsin substrates shed from the surface of cancer cells

Barbara SobotičMatej VizovišekRobert VidmarPetra Van DammeVasilena GochevaJohanna A JoyceKris GevaertVito TurkBoris TurkMarko Fonović

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Quantitative proteomics reveals altered expression of actin binding proteins after LMNA knockdown in human dermal fibroblasts

Tobias CorneTom SieprathJonathan VandenbusscheKris GevaertWinnok De Vos

Robust peptide-based models in quantitative proteomics

Ludger GoeminneKlaas VandepoeleKris GevaertLieven Clement

Structural investigation of B-Raf paradox breaker and inducer inhibitors

Rohit AroraMichela Di MicheleElisabeth StesElien VandermarliereLennart MartensKris GevaertErika Van HeerdeJoannes TM LindersDirk BrehmerEdgar Jacoby et al.

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Study of protein expresion [sic] in peri-infarct tissue after cerebral ischemia

David BreaJesús AgullaAn StaesKris GevaertFrancisco CamposTomás SobrinoMiguel BlancoAntoni DávalosJosé CastilloPedro Ramos-Cabrer

A1 Journal Article in SCIENTIFIC REPORTS

The RING E3 ligase KEEP ON GOING modulates JASMONATE ZIM-DOMAIN12 stability

Laurens PauwelsAndrés Ritter TraubJonas GoossensAstrid Nagels DurandHongxia LiuYangnan GuJan GeerinckMarta BoterRobin Vanden BosscheRebecca De Clercq et al.

A1 Journal Article in PLANT PHYSIOLOGY

The iceLogo web server and SOAP service for determining protein consensus sequences

Davy MaddeleinNiklaas ColaertIain BuchananNiels HulstaertKris GevaertLennart Martens

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Toll-like receptor 4 engagement on dendritic cells restrains phago-lysosome fusion and promotes cross-presentation of antigens

Andrés AlloattiFiorlla KotsiasAnne-Marie PauwelsJean-Marie CarpierMabel JouveEvy TimmermanLuigia PacePablo VargasMathieu MaurinUlf Gehrmann et al.

A1 Journal Article in IMMUNITY

Variable glutamine-rich repeats modulate transcription factor activity

Rita GemayelSreenivas ChavaliKsenia PougachMatthieu LegendreBo ZhuSteven BoeynaemsElisa van der ZandeKris GevaertFrederic RousseauJoost Schymkowitz et al.

A1 Journal Article in MOLECULAR CELL

2014

A COFRADIC protocol to study protein ubiquitination

Elisabeth StesMathias LagaAlan WaltonNoortje SamynEvy TimmermanIve De SmetSofie GoormachtigKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

A Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-Terminal Acetyltransferase NAA10 Ser37Pro Mutant

Petra Van DammeSvein I. StøveNina GlomnesKris GevaertThomas Arnesen

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

A proteogenomics approach integrating proteomics and ribosome profiling increases the efficiency of protein identification and enables the discovery of alternative translation start sites

Alexander KochDaria FijalkowskaSandra SteyaertElvis NdahJeroen CrappéSarah De KeulenaerEllen De MeesterMing MaBen ShenKris Gevaert et al.

A1 Journal Article in PROTEOMICS

ANGUSTIFOLIA3 binds to SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development

Liesbeth VercruyssenAurine VerkestNathalie Gonzalez SanchezKen HeyndrickxDominique EeckhoutSoon-Ki HanTeddy JéguRafal ArchackiJelle Van LeeneMegan Andriankaja et al.

A1 Journal Article in PLANT CELL

Arabidopsis thaliana RNase H2 deficiency counteracts the needs for the WEE1 checkpoint kinase but triggers genome instability

Pooneh KalhorzadehZhubing HuToon CoolsSimon AmiardEva-Maria WillingNancy De WinneKris GevaertGeert De JaegerKorbinian SchneebergerCharles I White et al.

A1 Journal Article in PLANT CELL

Early targets of miR-34a in neuroblastoma

Pasqualino De AntonellisMarianeve CarotenutoJonathan VandenbusscheGennaro De VitaVeronica FerrucciChiara MedagliaIolanda BoffaAlessandra GalieroSarah Di SommaDaniela Magliulo et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Granzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis

SAH de PootKW LaiL van der WalKim PlasmanPetra Van DammeAC PorterKris GevaertN Bovenschen

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Holistic view on the extended substrate specificities of orthologous granzymes

Kim PlasmanSebastian Maurer-StrohKris GevaertPetra Van Damme

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

How has urinary proteomics contributed to the discovery of early biomarkers of acute kidney injury?

Jorien De LoorKris GevaertEric HosteEvelyne Meyer

A1 Journal Article in EXPERT REVIEW OF PROTEOMICS

Identification of Serpinb6b as a species-specific mouse granzyme A inhibitor suggests functional divergence between human and mouse granzyme A

Dion KaisermanSarah E StewartKim PlasmanKris GevaertPetra Van DammePhillip I Bird

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Importance of extended protease substrate recognition motifs in steering BNIP-2 cleavage by human and mouse granzymes B

Petra Van DammeKim PlasmanGiel VandemoorteleVeronique JonckheereSebastian Maurer-StrohKris Gevaert

A1 Journal Article in BMC BIOCHEMISTRY

PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling

Vanessa A MoraisDominik HaddadKatleen CraessaertsPieter-Jan De BockJef SwertsSven VilainLiesbeth AertsLut OverberghAnne GrünewaldPhilip Seibler et al.

A1 Journal Article in SCIENCE

Preparation of Arabidopsis thaliana seedling proteomes for identifying metacaspase substrates by N-terminal COFRADIC

Styliani TsiatsianiSimon StaelPetra Van DammeFrank Van BreusegemKris Gevaert

Bookchapter in Caspases, paracaspases, and metacaspases : methods and protocols

Proteomics methods to study methionine oxidation

Bart GhesquièreKris Gevaert

A1 Journal Article in MASS SPECTROMETRY REVIEWS

Quantitative proteomics reveals differential effects of ZMPSTE24 and LMNA knockdown on human fibroblasts

Tobias CorneTom SieprathJonathan VandenbusscheKris GevaertWinnok De Vos

Substrate specificities of the granzyme tryptases A and K

Kim PlasmanHans DemolPhilip I BirdKris GevaertPetra Van Damme

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Sulfenome mining in Arabidopsis thaliana

Cezary WaszczakMosammat Salma AkterDominique EeckhoutGeert PersiauKhadija WahniNandita BodraInge Van MolleBarbara De SmetDidier VertommenKris Gevaert et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Taximin, a conserved plant-specific peptide is involved in the modulation of plant-specialized metabolism

Miriam OnrubiaJacob PollierRobin Vanden BosscheMarc GoethalsKris GevaertElisabet MoyanoHeriberto Vidal-LimonRosa M CusidóJavier PalazónAlain Goossens

A1 Journal Article in PLANT BIOTECHNOLOGY JOURNAL

The Non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor

Amparo Cuéllar PérezAstrid Nagels DurandRobin Vanden BosscheRebecca De ClercqGeert PersiauSaskia C. M. Van WeesCorné M. J. PieterseKris GevaertGeert De JaegerAlain Goossens et al.

A1 Journal Article in PLOS ONE

The TPLATE adaptor complex drives clathrin-mediated endocytosis in plants

Astrid GadeyneClara Sánchez-RodríguezSteffen VannesteSimone Di RubboHenrik ZauberKevin VannesteJelle Van LeeneNancy De WinneDominique EeckhoutGeert Persiau et al.

A1 Journal Article in CELL

The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy

Tom CornelissenDominik HaddadFieke WautersCindy Van HumbeeckWim MandemakersBrianada KoentjoroCarolyn SueKris GevaertBart De StrooperPatrik Verstreken et al.

A1 Journal Article in HUMAN MOLECULAR GENETICS

The proteome under translational control

Daria FijalkowskaKris GevaertPetra Van Damme

A1 Journal Article in PROTEOMICS

Unraveling the specificities of the different human methionine sulfoxide reductases

Elien VandermarliereBart GhesquièreVeronique JonckheereKris GevaertLennart Martens

A1 Journal Article in PROTEOMICS

qcML: an exchange format for quality control metrics from mass spectrometry experiments

Mathias WalzerLucia Espona PernasSara NassoWout BittremieuxSven NahnsenPieter KelchtermansPeter PichlerHenk WP van den ToornAn StaesJonathan Vandenbussche et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

2013

A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis

Katrien Van ImpeJonas BethuyneSteven CoolFrancis ImpensDavid Ruano-GallegoOlivier De WeverBerlinda VanlooMarleen Van TroysKathleen LambeinCiska Boucherie et al.

A1 Journal Article in BREAST CANCER RESEARCH

A protein phosphatase 2A complex spatially controls plant cell division

Lara SpinnerAstrid GadeyneKatia BelcramMagali GoussotMichael MoisonYann DurocDominique EeckhoutNancy De WinneEstelle SchaeferEveline Van De Slijke et al.

A1 Journal Article in NATURE COMMUNICATIONS

Activation of ADF/cofilin by phosphorylation-regulated Slingshot phosphatase is required for the meiotic spindle assembly in Xenopus laevis oocytes

Shohei IwaseRyuhei SatoPieter-Jan De BockKris GevaertSaburo FujikiToshinobu TawadaMiyako KuchitsuYuka YamagishiShoichiro OnoHiroshi Abe

A1 Journal Article in MOLECULAR BIOLOGY OF THE CELL

Asn₃, a reliable, robust, and universal lock mass for improved accuracy in LC-MS and LC-MS/MS

An StaesJonathan VandenbusscheHans DemolMarc GoethalsSule Yilmaz-RumpfNiels HulstaertSven DegroevePieter KelchtermansLennart MartensKris Gevaert

A1 Journal Article in ANALYTICAL CHEMISTRY

Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation

Ilse BeckZuzanna DrebertRuben Hoya-AriasAli A BaharMichael DevosDorien ClarisseSofie DesmetNadia BougarneBart RuttensValerie Gossye et al.

A1 Journal Article in PLOS ONE

Conservation of the extended substrate specificity profiles among homologous granzymes across species

Kim PlasmanSebastian Maurer-StrohJamshaid AhmadHan HaoDion KaisermanFernanda L SirotaVeronique JonckheerePhilip I BirdKris GevaertPetra Van Damme

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Constitutively active UVR8 photoreceptor variant in Arabidopsis

Marc HeijdeMelanie BinkertRuohe YinFlorence Ares-OrpelLuca RizziniEveline Van De SlijkeGeert PersiauJonah NolfKris GevaertGeert De Jaeger et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contemporary positional proteomics strategies to study protein processing

Kim PlasmanPetra Van DammeKris Gevaert

A1 Journal Article in CURRENT OPINION IN CHEMICAL BIOLOGY

Deep proteome coverage based on ribosome profiling aids mass spectrometry-based protein and peptide discovery and provides evidence of alternative translation products and near-cognate translation initiation events

Gerben MenschaertWim Van CriekingeTineke NotelaersAlexander KochJeroen CrappéKris GevaertPetra Van Damme

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Development of an enzyme-linked immunosorbent assay for detection of cellular and in vivo LRRK2 S935 phosphorylation

Lore DelbroekKristof Van KolenLiesbeth SteegmansRaquel da CunhaWim MandemakersGuy DaneelsPieter-Jan De BockJinwei ZhangKris GevaertBart De Strooper et al.

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Early targets of MIR-34A in neuroblastoma

P De AntonellisM CarotenutoG De VitaJonathan VandenbusscheC MedagliaJ VandesopeleP MestdaghLennart MartensAn StaesKathleen Moens et al.

Effect of phospholipid molecular structure on its interaction with whey proteins in aqueous solution

Marios KasinosPaolo SabatinoBerlinda VanlooKris GevaertJosé MartinsPaul Van der Meeren

A1 Journal Article in FOOD HYDROCOLLOIDS

Effect of sodium nitrite on protein oxidation in pork myofibrillar proteins

Els VossenKris GevaertStefaan De Smet

HPLC-based quantification of in vitro N-terminal acetylation

Rune H. EvjenthPetra Van DammeKris GevaertThomas Arnesen

Bookchapter in Protein Acetylation : Methods and Protocols

High entomotoxicity and mechanism of the fungal GalNAc/Gal-specific Rhizoctonia solani lectin in pest insects

Mohamad HamshouEls Van DammeSilvia CacciaKaat CappelleGianni VandenborreBart GhesquièreKris GevaertGuy Smagghe

A1 Journal Article in JOURNAL OF INSECT PHYSIOLOGY

Improving the identification rate of endogenous peptides using electron transfer dissociation and collision-induced dissociation

Eisuke HayakawaGerben MenschaertPieter-Jan De BockWalter LuytenKris GevaertGeert BaggermanLiliane Schoofs

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

In-gel N-acetylation for the quantification of the degree of protein in vivo N-terminal acetylation

Petra Van DammeThomas ArnesenBart RuttensKris Gevaert

Bookchapter in Protein Acetylation : Methods and Protocols

LNCipedia 2.0: a database for annotated human lncRNA transcript sequences and structures

Pieter-Jan VoldersKenny HelsensXiaowei WangLennart MartensKris GevaertJo VandesompelePieter Mestdagh

LNCipedia 2.0: a database for annotated human lncRNA transcript sequences and structures

Pieter-Jan VoldersKenny HelsensXiaowei WangLennart MartensKris GevaertJo VandesompelePieter Mestdagh

LNCipedia : a database for annotated human lncRNA transcript sequences and structures

Pieter-Jan VoldersKenny HelsensXiaowei WangBjörn MentenLennart MartensKris GevaertJo VandesompelePieter Mestdagh

A1 Journal Article in NUCLEIC ACIDS RESEARCH

LNCipedia: a database for annotated human lncRNA transcript sequences and structures

Pieter-Jan VoldersKenny HelsensXiaowei WangLennart MartensKris GevaertJo VandesompelePieter Mestdagh

Mapping proteolytic processing in the secretome of gastric cancer-associated myofibroblasts reveals activation of MMP-1, MMP-2, and MMP-3

Christopher HolmbergBart GhesquièreFrancis ImpensKris GevaertJ Dinesh KumarNicole CashSandhir KandolaPeter HegyiTimothy C WangGraham J Dockray et al.

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF

Roosmarijn VandenbrouckeEline DejonckheereFilip Van HauwermeirenSofie LodensRiet De RyckeElien Van WonterghemAn StaesKris GevaertCarlos López-OtinClaude Libert

A1 Journal Article in EMBO MOLECULAR MEDICINE

Plant proteins under oxidative attack

Silke JacquesBart GhesquièreFrank Van BreusegemKris Gevaert

A1 Journal Article in PROTEOMICS

Protein N-terminal acetyltransferases act as N-terminal propionyltransferases in vitro and in vivo

Håvard FoynPetra Van DammeSvein I StøveNina GlomnesRune EvjenthKris GevaertThomas Arnesen

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Proteome studies of bacterial antibiotic resistance mechanisms

Iosif VranakisIoannis GoniotakisAnna PsaroulakiVassilios SandalakisYannis TselentisKris GevaertGeorgios Tsiotis

A1 Journal Article in JOURNAL OF PROTEOMICS

Proteome-derived peptide libraries to study the substrate specificity profiles of carboxypeptidases

Sebastian TancoJulia LorenzoJavier Garcia-PardoSven DegroeveLennart MartensFrancesc Xavier AvilesKris GevaertPetra Van Damme

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Proteomic and metabolomic responses to connexin43 silencing in primary hepatocyte cultures

Mathieu VinkenMichaël MaesRachel CavillDirk ValkenborgJames K EllisElke DecrockLuc LeybaertAn StaesKris GevaertAndré G Oliveira et al.

A1 Journal Article in ARCHIVES OF TOXICOLOGY

SCX charge state selective separation of tryptic peptides combined with 2D-RP-HPLC allows for detailed proteome mapping

Lazaro H BetancourtPieter-Jan De BockAn StaesEvy TimmermanYasset Perez-RiverolAniel SanchezVladimir BesadaLuis Javier GonzalezJoël VandekerckhoveKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOMICS

The Arabidopsis METACASPASE9 degradome

Styliani TsiatsianiEvy TimmermanPieter-Jan De BockDominique VercammenSimon StaelBrigitte Van De CotteAn StaesMarc GoethalsTine BeunensPetra Van Damme et al.

A1 Journal Article in PLANT CELL

The Online Protein Processing Resource (TOPPR) : a database and analysis platform for protein processing events

Niklaas ColaertDavy MaddeleinFrancis ImpensPetra Van DammeKim PlasmanKenny HelsensNiels HulstaertJoël VandekerckhoveKris GevaertLennart Martens

A1 Journal Article in NUCLEIC ACIDS RESEARCH

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

Michal SimicekSam LievensMathias LagaDmytro GuzenkoVasily N AushevPeter KalevMaria Francesca BaiettiSergei V StrelkovKris GevaertJan Tavernier et al.

A1 Journal Article in NATURE CELL BIOLOGY

Unraveling substrate repertoires and specificities of orthologous granzymes by peptide-based, gel-free proteomics

Kim PlasmanKris GevaertPetra Van Damme

Vpr content of HIV-1 virions determines infection of resting peripheral blood CD4⁺ lymphocytes

Anouk Van NuffelFrancis ImpensAnn BaeyensStijn VanheeWojciech WitkowskiElien VandermarliereHanne VanderstraetenEvelien NaessensKathleen Van LandeghemSophie Vermaut et al.

2012

A catalogue of putative HIV-1 protease host cell substrates

Francis ImpensEvy TimmermanAn StaesKathleen MoensKevin AriënBruno VerhasseltJoël VandekerckhoveKris Gevaert

A1 Journal Article in BIOLOGICAL CHEMISTRY

A novel strategy for the comprehensive analysis of the biomolecular composition of isolated plasma membranes

Deepak B Thimiri Govinda RajBart GhesquièreArun Kumar Tharkeshwar RaghunathKatrijn CoenRita DeruaDieter VanderschaegheEvelien RysmanMurali BagadiPieter BaatsenBart De Strooper et al.

Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity

Davina TondeleirAnja LambrechtsMatthias MüllerVeronique JonckheereThierry DollDrieke VandammeKarima BakkaliDavy WaterschootMarianne LemaistreOlivier Debeir et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Chitinase-like proteins are candidate biomarkers for sepsis-induced acute kidney injury

Bert MaddensBart GhesquièreRaymond VanholderDieter DemonJ VanmassenhoveKris GevaertEvelyne Meyer

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike

Magdalena WejdaFrancis ImpensNozomi TakahashiPetra Van DammeKris GevaertPeter Vandenabeele

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

GalNAc/Gal-binding Rhizoctonia solani agglutinin has antiproliferative activity in Drosophila melanogaster S2 cells via MAPK and JAK/STAT signaling

Mohamad HamshouEls Van DammeGianni VandenborreBart GhesquièreGeert TrooskensKris GevaertGuy Smagghe

A1 Journal Article in PLOS ONE

How many spots with missing values can be tolerated in quantitative two-dimensional gel electrophoresis when applying univariate statistics?

Maria ZellnerAlexandra GrafSonja ZehetmayerWolfgang WinklerAn StaesKris GevaertJoël VandekerckhoveMartina Marchetti-DeschmannIngrid MillerPeter Bauer et al.

A1 Journal Article in JOURNAL OF PROTEOMICS

Interaction of α-catulin with dystrobrevin contributes to integrity of dystrophin complex in muscle

Hyun J OhLinu S AbrahamJolanda van HengelChristophe StoveTomasz J ProszynskiKris GevaertJoseph X DiMarioJoshua R SanesFrans Van RoyHongkyun Kim

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Investigation of rifampicin resistance mechanisms in Brucella abortus using MS-driven comparative proteomics

Vassilios SandalakisAnna PsaroulakiPieter-Jan De BockAthanasia ChristidouKris GevaertGeorgios TsiotisYiannis Tselentis

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis

Samer MattaKristof Van KolenRaquel da CunhaGeert van den BogaartWim MandemakersKatarzyna MiskiewiczPieter-Jan De BockVanessa A MoraisSven VilainDominik Haddad et al.

A1 Journal Article in NEURON

Lncipedia: a novel database for annotated lncRNA sequences and structures

Pieter-Jan VoldersKenny HelsensXiaowei WangLennart MartensKris GevaertJo VandesompelePieter Mestdagh

N-terminal acetylation and other functions of Nα-acetyltransferases

Jolien HollebekePetra Van DammeKris Gevaert

A1 Journal Article in BIOLOGICAL CHEMISTRY

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB

Petra Van DammeMarta LasaBogdan PolevodaCristina GazquezAlberto Elosegui-ArtolaDuk Soo KimElena De Juan-PardoKimberly DemeyerKristine HoleEsther Larrea et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural substrates of plant proteases: how can protease degradomics extend our knowledge?

Styliani TsiatsianiKris GevaertFrank Van Breusegem

A1 Journal Article in PHYSIOLOGIA PLANTARUM

Protein N-terminal acetyltransferases: when the start matters

Kristian K StarheimKris GevaertThomas Arnesen

A1 Journal Article in TRENDS IN BIOCHEMICAL SCIENCES

Proteome profiling of the green sulfur bacterium Chlorobaculum tepidum by N-terminal proteomics

Kalliopi KouyianouPieter-Jan De BockNiklaas ColaertAntigoni NikolakiAikaterini AktoudianakiKris GevaertGeorgios Tsiotis

A1 Journal Article in PROTEOMICS

Quantitative proteome profiling of C. burnetii under tetracycline stress conditions

Iosif VranakisPieter-Jan De BockAnastasia PapadiotiYannis TselentisKris GevaertGeorgios TsiotisAnna Psaroulaki

A1 Journal Article in PLOS ONE

Study of the whole cell lysate of two Coxiella burnetii strains using N-Terminomics

Anastatia PapadiotiPieter-Jan De BockIosif VranakisYiannis TselentisKris GevaertAnna PsaroulakiGeorgios Tsiotis

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

The Apaf-1-binding protein Aven is cleaved by Cathepsin D to unleash its anti-apoptotic potential

IM MelzerSBM FernándezS BösserK LohrigU LewandrowskiD WoltersS KehrloesserM-L BrezniceanuAC TheosPM Irusta et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

The multifunctionality of Arabidopsis metacaspases highlighted by their degradomes

Styliani TsiatsianiFrank Van BreusegemKris Gevaert

The neural cell adhesion molecules L1 and CHL1 are cleaved by BACE1 protease in vivo

LuJia ZhouSoraia BaraoMathias LagaKatrijn BockstaelMarianne BorgersHarry GijsenWim AnnaertDiederik MoecharsMarc MerckenKris Gevaert et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2011

A case study on the comparison of different software tools for automated quantification of peptides

Niklaas ColaertJoël VandekerckhoveLennart MartensKris Gevaert

Bookchapter in Gel-free proteomics : methods and protocols

A comparison of MS2-based label-free quantitative proteomic techniques with regards to accuracy and precision

Niklaas ColaertJoël VandekerckhoveKris GevaertLennart Martens

A1 Journal Article in PROTEOMICS

A novel strategy for the comprehensive analysis of the biomolecular composition of isolated plasma membranes

Deepak B Thimiri Govinda RajBart GhesquièreArun Kumar Tharkeshwar RaghunathKatrijn CoenRita DeruaDieter VanderschaegheEvelien RysmanMurali BagadiPieter BaatsenBart De Strooper et al.

A1 Journal Article in MOLECULAR SYSTEMS BIOLOGY

A reproducibility-based evaluation procedure for quantifying the differences between MS/MS peak intensity normalization methods

Sven DegroeveNiklaas ColaertJoël VandekerckhoveKris GevaertLennart Martens

A1 Journal Article in PROTEOMICS

A stringent approach to improve the quality of nitrotyrosine peptide identifications

Bart GhesquièreKenny HelsensJoël VandekerckhoveKris Gevaert

A1 Journal Article in PROTEOMICS

Angiotensin I-converting enzyme inhibitory activity of gelatin hydrolysates and identification of bioactive peptides

Griet HerregodsJohn Van CampNicole MorelBart GhesquièreKris GevaertLieselot VercruysseStephan DierckxErwin QuantenGuy Smagghe

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bioinformatics analysis of a Saccharomyces cerevisiae N-terminal proteome provides evidence of alternative translation initiation and post-translational N-terminal acetylation

Kenny HelsensPetra Van DammeSven DegroeveLennart MartensThomas ArnesenJoël VandekerckhoveKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin

Esther HostePatrick KempermanMichael DevosGeertrui DeneckerSanja KezicNico YauBarbara GilbertSaskia LippensPhilippe De GrooteRia Roelandt et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Combining quantitative proteomics data processing workflows for greater sensitivity

Niklaas ColaertChristophe Van HueleSven DegroeveAn StaesJoël VandekerckhoveKris GevaertLennart Martens

A1 Journal Article in NATURE METHODS

Digging deeper in the data, novel approaches and analysis methods in quantitative peptide-centric proteomics

Niklaas ColaertKris GevaertLennart Martens

Diversity in protein glycosylation among insect species

Gianni VandenborreGuy SmaggheBart GhesquièreGerben MenschaertNagender RaoKris GevaertEls Van Damme

A1 Journal Article in PLOS ONE

Human and mouse granzyme M display divergent and species-specific substrate specificities

Stefanie AH de PootMarijn WestgeestDaniel R HostetterPetra Van DammeKim PlasmanKimberly DemeyerRoel BroekhuizenKris GevaertCharles S CraikNiels Bovenschen

A1 Journal Article in BIOCHEMICAL JOURNAL

Identification of potentially involved proteins in levofloxacin resistance mechanisms in Coxiella burnetii

Iosif VranakisPieter-Jan De BockAnastasia PapadiotiYannis TselentisKris GevaertGeorgios TsiotisAnna Psaroulaki

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Interaction of the tobacco lectin with histone proteins

Dieter SchouppeBart GhesquièreGerben MenschaertWinnok De VosStéphanie BourqueGeert TrooskensPaul ProostKris GevaertEls Van Damme

A1 Journal Article in PLANT PHYSIOLOGY

Lectins as tools to select for glycosylated proteins

Bookchapter in Gel-free proteomics : methods and protocols

N-Terminal combined fractional diagonal chromatographic (COFRADIC) analysis of the human platelet proteome

Francis ImpensKenny HelsensNiklaas ColaertLennart MartensJoël VandekerckhoveKris Gevaert

Bookchapter in Platelet proteomics : principles, analysis, and applications

NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation

Petra Van DammeKristine HoleAna Pimenta-MarquesKenny HelsensJoël VandekerckhoveRui G MartinhoKris GevaertThomas Arnesen

A1 Journal Article in PLOS GENETICS

Parkin interacts with Ambra1 to induce mitophagy

Cindy Van HumbeeckTom CornelissenHilde HofkensWim MandemakersKris GevaertBart De StrooperWim Vandenberghe

A1 Journal Article in JOURNAL OF NEUROSCIENCE

Probing the efficiency of proteolytic events by positional proteomics

Kim PlasmanPetra Van DammeDion KaisermanFrancis ImpensKimberly DemeyerKenny HelsensMarc GoethalsPhillip I BirdJoël VandekerckhoveKris Gevaert

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Protein alpha-N-acetylation studied by N-terminomics

Petra Van DammeThomas ArnesenKris Gevaert

A1 Journal Article in FEBS JOURNAL

Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of Nα-acetyltransferases and point to hNaa10p as the post-translational actin Nα-acetyltransferase

Petra Van DammeRune EvjenthHavard FoynKimberly DemeyerPieter-Jan De BockJohan R LillehaugJoël VandekerckhoveThomas ArnesenKris Gevaert

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

RIBAR and xRIBAR: methods for reproducible relative MS/MS-based label-free protein quantification

Niklaas ColaertKris GevaertLennart Martens

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Redox proteomics of protein-bound methionine oxidation

Bart GhesquièreVeronique JonckheereNiklaas ColaertJoost Van DurmeEvy TimmermanMarc GoethalsJoost SchymkowitzFrederic RousseauJoël VandekerckhoveKris Gevaert

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Selecting protein N-terminal peptides by combined fractional diagonal chromatography

An StaesFrancis ImpensPetra Van DammeBart RuttensMarc GoethalsHans DemolEvy TimmermanJoël VandekerckhoveKris Gevaert

A1 Journal Article in NATURE PROTOCOLS

Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy

Leonardo Almeida-SouzaBob AsselberghConstantin d'YdewalleKristof MoonensSofie GoethalsVicky de WinterAbdelkarim AzmiJoy IrobiJean-Pierre TimmermansKris Gevaert et al.

A1 Journal Article in JOURNAL OF NEUROSCIENCE

T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1

Jens StaalYasmine DriegeTine BekaertAnnelies DemeyerDavid MuyllaertPetra Van DammeKris GevaertRudi Beyaert

A1 Journal Article in EMBO JOURNAL

The chlorosome of Chlorobaculum tepidum: size, mass and protein composition revealed by electron microscopy, dynamic light scattering and mass spectrometry-driven proteomics

K KouyianouPieter-Jan De BockSA MullerA NikolakiA RizosV KrzyzanekA AktoudianakiJoël VandekerckhoveA EngelKris Gevaert et al.

A1 Journal Article in PROTEOMICS

The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4

Kristine HolePetra Van DammeMonica DalvaHenriette AksnesNina GlomnesJan Erik VarhaugJohan R LillehaugKris GevaertThomas Arnesen

A1 Journal Article in PLOS ONE

The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma

Pieter MestdaghAna-Karin BostromFrancis ImpensErik FredlundGert Van PeerPaquito De AntonelisKristoffer Von StedingkBart GhesquièreStefanie SchulteMichael Dews et al.

cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)

Mathieu BertrandSaskia LippensAn StaesBarbara GilbertRia RoelandtJelle De MedtsKris GevaertWim DeclercqPeter Vandenabeele

A1 Journal Article in PLOS ONE

m-Calpain activation in vitro does not require autolysis or subunit dissociation

Jordan S ChouFrancis ImpensKris GevaertPeter L Davies

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

thermo-msf-parser: an open source Java library to parse and visualize Thermo Proteome Discoverer msf files

Niklaas ColaertHarald BarsnesMarc VaudelKenny HelsensEvy TimmermanAlbert SickmannKris GevaertLennart Martens

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

2010

A quantitative proteomics design for systematic identification of protease cleavage events

Francis ImpensNiklaas ColaertKenny HelsensBart GhesquièreEvy TimmermanPieter-Jan De BockBenjamin M ChainJoël VandekerckhoveKris Gevaert

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Complementary positional proteomics for screening substrates of endo- and exoproteases

Petra Van DammeAn StaesSilvia BronsomsKenny HelsensNiklaas ColaertEvy TimmermanFrancesc X AvilesJoël VandekerckhoveKris Gevaert

A1 Journal Article in NATURE METHODS

Glycosylation signatures in Drosophila : fishing with lectins

Gianni VandenborreEls Van DammeBart GhesquièreGerben MenschaertMohamad HamshouRameshwaram Nagender RaoKris GevaertGuy Smagghe

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Increasing the specificity and the sensitivity in peptide centric proteomics

Kenny HelsensKris GevaertLennart Martens

Integrated proteomic analysis reveals a substantial enrichment of protein trafficking processes in hippocampus tissue after hypoxic stress

Roos Van ElzenBart GhesquièreEvy TimmermanStefaan VandammeLuc MoensKris GevaertSylvia Dewilde

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Listeria monocytogenes impairs SUMOylation for efficient infection

David RibetMelanie HamonEdith GouinMarie-Anne NahoriFrancis ImpensHelene Neyret-KahnKris GevaertJoël VandekerckhoveAnne DejeanPascale Cossart

A1 Journal Article in NATURE

MS-driven protease substrate degradomics

Francis ImpensNiklaas ColaertKenny HelsensKim PlasmanPetra Van DammeJoël VandekerckhoveKris Gevaert

A1 Journal Article in PROTEOMICS

Membrane proteome of the green sulfur bacterium Chlorobium tepidum (syn. Chlorobaculum tepidum) analyzed by gel-based and gel-free methods

Kalliopi KouyianouMichalis AivaliotisKris GevaertMichael KarasGeorgios Tsiotis

A1 Journal Article in PHOTOSYNTHESIS RESEARCH

Rover: a tool to visualize and validate quantitative proteomics data from different sources

Niklaas ColaertKenny HelsensFrancis ImpensJoël VandekerckhoveKris Gevaert

A1 Journal Article in PROTEOMICS

Studying in vitro and in vivo protease processing in models of cancer cell death and viral infection by N-terminal COFRADIC

Francis ImpensKris Gevaert

The chaperone-like Protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation

Thomas ArnesenKristian K StarheimPetra Van DammeRune EvjenthHuyen DinhMatthew J BettsAnita RyningenJoël VandekerckhoveKris GevaertDave Anderson

A1 Journal Article in MOLECULAR AND CELLULAR BIOLOGY

The miR-17-92 MicroRNA Cluster regulates multiple components of the TGF-beta Pathway in neuroblastoma

Pieter MestdaghAnna-Karin BostromFrancis ImpensErik FredlundGert Van PeerPasqualino De AntonellisKristoffer von StedingkBart GhesquièreStefanie SchulteMichael Dews et al.

A1 Journal Article in MOLECULAR CELL

The substrate specificity profile of human granzyme A

Petra Van DammeSebastian Maurer-StrohHan HaoNiklaas ColaertEvy TimmermanFrank EisenhaberJoël VandekerckhoveKris Gevaert

A1 Journal Article in BIOLOGICAL CHEMISTRY

Who gets cut during cell death?

Francis ImpensJoël VandekerckhoveKris Gevaert

A1 Journal Article in CURRENT OPINION IN CELL BIOLOGY

mir-17-92 is a master regulator of TGFβ-pathway activity in neuroblastoma

Pieter MestdaghAnna-Karin BöstromFrancis ImpensErik FredlundKris Von StedingkBart GhesquièreStefanie SchlierfJohannes SchulteAlexander SchrammKris Gevaert et al.

ms_lims, a simple yet powerful open source laboratory information management system for MS-driven proteomics

Kenny HelsensNiklaas ColaertHarald BarsnesThilo MuthKristian FlikkaAn StaesEvy TimmermanSteffi WortelkampAlbert SickmannJoël Vandekerckhove et al.

A1 Journal Article in PROTEOMICS

2009

A review of COFRADIC techniques targeting protein N-terminal acetylation

Petra Van DammeJozef Van DammeHans DemolAn StaesJoël VandekerckhoveKris Gevaert

Analysis of Protein Processing by N-terminal Proteomics Reveals Novel Species-specific Substrate Determinants of Granzyme B Orthologs

Petra Van DammeSebastian Maurer-StrohKim PlasmanJoost Van DurmeNiklaas ColaertEvy TimmermanPieter-Jan De BockMarc GoethalsFrederic RousseauJoost Schymkowitz et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Analysis of proteins in Chlamydia trachomatis L2 outer membrane complex, COMC

Svend BirkelundMarie Morgan-FisherEvy TimmermanKris GevaertAllan C. ShawGunna Christiansen

A1 Journal Article in FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains

T WakabayashiK CraessaertsL BammensM BentahirF BorgionsP HerdewijnAn StaesEvy TimmermanJoël VandekerckhoveE Rubinstein et al.

A1 Journal Article in NATURE CELL BIOLOGY

Analysis of the translationally controlled tumour protein in the nematodes Ostertagia ostertagi and Caenorhabditis elegans suggests a pivotal role in egg production

Yves MeyvisWouter HouthoofdAline VisserGaetan BorgonieKris GevaertJozef VercruysseEdwin ClaereboutPeter Geldhof

A1 Journal Article in INTERNATIONAL JOURNAL FOR PARASITOLOGY

Caspase substrates: easily caught in deep waters?

Dieter DemonPetra Van DammeTom Vanden BergheJoël VandekerckhoveWim DeclercqKris GevaertPeter Vandenabeele

A1 Journal Article in TRENDS IN BIOTECHNOLOGY

Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability

FN VogtleS WortelkampRP ZahediD BeckerC LeidholdKris GevaertJ KellermannW VoosA SickmannN Pfanner et al.

A1 Journal Article in CELL

Hybrid N-glycans on the host protective activation-associated secreted proteins of Ostertagia ostertagi and their importance in immunogenicity (vol 161, pg 67, 2008)

Yves MeyvisNico CallewaertKris GevaertEvy TimmermanJoost Van DurmeJoost SchymkowitzFrederic RousseauJozef VercruysseEdwin ClaereboutPeter Geldhof

Identification and Functional Characterization of N-Terminally Acetylated Proteins in Drosophila melanogaster

S GoetzeE QeliC MosimannAn StaesB GerritsB RoschitzkiS MohantyEM NiedererE LaczkoEvy Timmerman et al.

A1 Journal Article in PLOS BIOLOGY

Identification of Chlamydia trachomatis CT621, a protein delivered through the type III secretion system to the host cell cytoplasm and nucleus

Anne-Sofie Hobolt-PedersenGunna ChristiansenEvy TimmermanKris GevaertSvend Birkelund

A1 Journal Article in FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Improved visualization of protein consensus sequences by iceLogo

Niklaas ColaertKenny HelsensLennart MartensJoël VandekerckhoveKris Gevaert

A1 Journal Article in NATURE METHODS

In vitro and in vivo protein-bound tyrosine nitration characterized by diagonal chromatography

Bart GhesquièreNiklaas ColaertKenny HelsensLien DejagerCaroline VanhauteKatleen VerleysenKoen KasEvy TimmermanMarc GoethalsClaude Libert et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity

Dieter DemonPetra Van DammeTom Vanden BergheAnnelies DeceuninckJoost Van DurmeJelle VerspurtenKenny HelsensFrancis ImpensMagdalena WejdaJoost Schymkowitz et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans

Thomas ArnesenPetra Van DammeBogdan PolevodaKenny HelsensRune EvjenthNiklaas ColaertJan Erik VarhaugJoël VandekerckhoveJohan LillehaugFred Sherman et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recessive osteogenesis imperfecta caused by LEPRE1 mutations: clinical documentation and identification of the splice form responsible for prolyl 3-hydroxylation

Andy WillaertFransiska MalfaitSofie SymoensKris GevaertH. KayseriliA. MegarbaneGeert MortierJ. G. LeroyPaul CouckeAnne De Paepe

A1 Journal Article in JOURNAL OF MEDICAL GENETICS

SitePredicting the cleavage of proteinase substrates

Jelle VerspurtenKris GevaertWim DeclercqPeter Vandenabeele

A1 Journal Article in TRENDS IN BIOCHEMICAL SCIENCES

Structure of granzyme C reveals an unusual mechanism of protease autoinhibition

Dion KaisermanAshley M BucklePetra Van DammeJames A. IrvingRuby H. P. LawAntony Y. MatthewsTanya Bashtannyk-PuhalovichChris LangendorfPhilip ThompsonJoël Vandekerckhove et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2008

A Hotspot Splicing Mutation in LEPREI Affects Prolyl 3-hydroxylation and Causes Recessive Osteogenesis Imperfecta

Andy WillaertSofie SymoensFransiska MalfaitKris GevaertPaul CouckeAnne De Paepe

Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death

Gro GausdalBjøorn Tore GjertsenEmmet McCormackPetra Van DammeRandi HovlandCamilla KrakstadØystein BruserudKris GevaertJoël VandekerckhoveStein Ove Døskeland

A1 Journal Article in BLOOD

Analysis of the transthyretin-like (TTL) gene family in Ostertagia ostertagi - Comparison with other strongylid nematodes and Caenorhabditis elegans

Heidi SaverwynsAline VisserJ VAN DURMED POWERI MORGADOMW KENNEDYDP KNOXJ SCHYMKOWITZF ROUSSEAUKris Gevaert et al.

A1 Journal Article in INTERNATIONAL JOURNAL FOR PARASITOLOGY

Analysis of the transthyretin-like (TTL) gene family in Ostertagia ostertagi: comparison with other strongylid nematodes and Caenorhabditis elegans

Aline VisserHeidi SaverwynsJ Van DurmeD PowerI MorgadoMW KennedyD KnoxJ SchymkowitzF RousseauKris Gevaert et al.

Caspase-14 is a crucial protease in proper stratum corneum formation

E HOSTEG DENECKERPetra Van DammeJ HACHEMB GILBERTPetra OvaereRB PRESLANDT MAKINON HUHPM ELIAS et al.

Disentanglement of protease substrate repertoires

Petra Van DammeJ VANDELKERCKHOVEKris Gevaert

A1 Journal Article in BIOLOGICAL CHEMISTRY

Function of the translationally controlled tumor protein in Ostertagia ostertagi and Caenorhabditis elegans

Yves MeyvisWouter HouthoofdAline VisserGaetan BorgonieKris GevaertJozef VercruysseEdwin ClaereboutPeter Geldhof

Gender-enriched transcription of activation associated secreted proteins in Ostertagia ostertagi

Aline VisserAnnelies Van ZeverenYves MeyvisIris PeelaersWim Van Den BroeckKris GevaertJozef VercruysseEdwin ClaereboutPeter Geldhof

A1 Journal Article in INTERNATIONAL JOURNAL FOR PARASITOLOGY

Human Proteinpedia enables sharing of human protein data

Suresh MathivananMukhtar AhmedNatalie G AhnHainard AlexandreRamars AmanchyPhilip C AndrewsJoel S BaderBrian M BalgleyMarcus BantscheffKeiryn L Bennett et al.

A1 Journal Article in NATURE BIOTECHNOLOGY

Hybrid N-glycans on the host protective activation-associated secreted proteins of Ostertagia ostertagi and their importance in immunogenicity

Yves MeyvisNico CallewaertKris GevaertEvy TimmermanJoost Van DurmeJoost SchymkowitzFrederic RousseauJozef VercruysseEdwin ClaereboutPeter Geldhof

A1 Journal Article in MOLECULAR AND BIOCHEMICAL PARASITOLOGY

HyperISGylation of old world monkey ISG15 in human cells

Els PattynAnnick VerheeIsabel UyttendaeleJulie PiessevauxEvy TimmermanKris GevaertJoël VandekerckhoveFrank PeelmanJan Tavernier

A1 Journal Article in PLOS ONE

Identification and characterization of a novel specific secreted protein family for selected members of the subfamily Ostertagiinae (Nematoda)

Heidi SaverwynsAline VisserAJ NisbetIris PeelaersKris GevaertJozef VercruysseEdwin ClaereboutPeter Geldhof

A1 Journal Article in PARASITOLOGY

Improved recovery of proteome-informative, protein N-terminal peptides by combined fractional diagonal chromatography (COFRADIC)

An StaesPetra Van DammeKenny HelsensHans DemolJoël VandekerckhoveKris Gevaert

A1 Journal Article in PROTEOMICS

Listeria comet tails: the actin-based motility machinery at work

Anja LambrechtsKris GevaertP COSSARTJoël VandekerckhoveMarleen Van Troys

A1 Journal Article in TRENDS IN CELL BIOLOGY

Mechanistic insight into taxol-induced cell death

Francis ImpensPetra Van DammeHans DemolJozef Van DammeJoël VandekerckhoveKris Gevaert

A1 Journal Article in ONCOGENE

Multiple isoforms of the tumor suppressor myopodin are simultaneously transcribed in cancer cells

Ariane De GanckVeerle De CorteAn StaesKris GevaertJoël VandekerckhoveJan Gettemans

A1 Journal Article in BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Peptizer: a tool for assessing false positive peptide identifications and manually validating selected results

Kenny HelsensEvy TimmermanJoël VandekerckhoveKris GevaertLennart Martens

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Protein processing characterized by a gel-free proteomics approach

Petra Van DammeFrancis ImpensJoël VandekerckhoveKris Gevaert

Bookchapter in Functional proteomics, part III

Stable isotopic labeling in proteomics

Kris GevaertFrancis ImpensBart GhesquièrePetra Van DammeAnja LambrechtsJoël Vandekerckhove

A1 Journal Article in PROTEOMICS

Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes

Mohamed LamkanfiThirumala-Devi KannegantiPetra Van DammeTom Vanden BergheIsabel VanoverbergheJoël VandekerckhovePeter VandenabeeleKris GevaertGabriel Nuñez

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

The Tandem PDZ Protein Syntenin Interacts with the Aminoacyl tRNA Synthetase Complex in a Lysyl-tRNA Synthetase-Dependent Manner

Kris MeerschaertEline RemueAriane De GanckAn StaesCiska BoucherieKris GevaertJoël VandekerckhoveLawrence KleimanJan Gettemans

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

The actin propulsive machinery: The proteome of Listeria monocytogenes tails

Marleen Van TroysAnja LambrechtsVera DavidHans DemolMagda PuypeJ PIZARRO-CERDAKris GevaertP COSSARTJoël Vandekerckhove

A1 Journal Article in BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The proteome of the human neuroblastoma cell line SH-SY5Y: an enlarged proteome

Kambiz GilanyRoos Van ElzenKim MousEdmond CoenWalter Van DongenStefaan VandammeKris GevaertEvy TimmermanJoël VandekerckhoveSylvia Dewilde et al.

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Unravelling the RIP4 signaling pathway to NF-kappa B

P DE GROOTES LIPPENSB GILBERTKris GevaertJoël VandekerckhoveP VANDENABEELEY DECLERCQ

2007

A la carte proteomics with an emphasis on gel-free techniques

Kris GevaertPetra Van DammeBart GhesquièreFrancis ImpensLennart MartensKenny HelsensJoël Vandekerckhove

A1 Journal Article in PROTEOMICS

A new approach for mapping sialylated N-glycosites in serum proteomes

Bart GhesquièreLien BuylHans DemolJozef Van DammeAn StaesEvy TimmermanJoël VandekerckhoveKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Applications of diagonal chromatography for proteome-wide characterization of protein modifications and activity-based analyses

Kris GevaertFrancis ImpensPetra Van DammeBart GhesquièreXavier HanoulleJoël Vandekerckhove

A1 Journal Article in FEBS JOURNAL

Assessing a novel microfluidic interface for shotgun proteome analyses

An StaesEvy TimmermanI VAN DAMMEKenny HelsensJoël VandekerckhoveM VOLLMERKris Gevaert

A1 Journal Article in JOURNAL OF SEPARATION SCIENCE

Caspase-14 protects against epidermal UVB photo-damage and water loss

Geertrui DeneckerEsther HosteBarbara GilbertTino HochepiedPetra OvaereSaskia LippensC VAN DEN BROUCKEPetra Van DammeKatharina D'HerdeJ HACHEM et al.

Caspase-14 protects against epidermal UVB photo-damage and water loss.

Geertrui DeneckerEsther HosteBarbara GilbertTino HochepiedPetra OvaereSaskia LippensC VAN DEN BROUCKEPetra Van DammeKatharina D'HerdeJ HACHEM et al.

Caspase-14 protects against epidermal UVB photodamage and water loss

Geertrui DeneckerEsther HosteBarbara GilbertTino HochepiedPetra OvaereSaskia LippensCaroline Van den broeckePetra Van DammeKatharina D'HerdeJP HACHEM et al.

A1 Journal Article in NATURE CELL BIOLOGY

Combination of COFRADIC and high temperature - extended column length conventional liquid chromatography: A very efficient way to tackle complex protein samples, such as serum

K SANDRAK VERLEYSENChristine LabeurL VANNESTEF D'HONDTG THOMASKoen KasKris GevaertJoël VandekerckhoveP SANDRA

A1 Journal Article in JOURNAL OF SEPARATION SCIENCE

Identification and characterization of filaggrin as a caspase-14 substrate

Esther HosteGeertrui DeneckerPetra Van DammeRB PRESLANDJoël VandekerckhoveKris GevaertPeter VandenabeeleWim Declercq

Implementation and application of a versatile clustering tool for tandem mass spectrometry data

Kristian FlikkaJeroen MeukensKenny HelsensJoël VandekerckhoveIngvar EidhammerKris GevaertLennart Martens

A1 Journal Article in PROTEOMICS

Large-scale identification of N-terminal peptides in the halophilic archaea Halobacterium salinarum and Natronomonas pharaonis

Michalis AivaliotisKris GevaertMichaela FalbAndreas TebbeKosta KonstantinidisBirgit BisleChristian KleinLennart MartensAn StaesEvy Timmerman et al.

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

MascotDatfile: an open-source library to fully parse and analyse MASCOT MS/MS search results

Kenny HelsensLennart MartensJoël VandekerckhoveKris Gevaert

A1 Journal Article in PROTEOMICS

Proteolytic cleavage of the Chlamydia pneumoniae major outer membrane protein in the absence of Pmp10

N JUULEvy TimmermanKris GevaertG CHRISTIANSENS BIRKELUND

A1 Journal Article in PROTEOMICS

Proteome-wide identification of HtrA2/Omi substrates

Lieselotte Vande WallePetra Van DammeMohamed LamkanfiXavier SaelensJoël VandekerckhoveKris GevaertPeter Vandenabeele

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

The C-terminus of CIS defines its interaction pattern

Delphine LavensPeter UlrichtsDominiek CatteeuwKris GevaertJoël VandekerckhoveFrank PeelmanSven EyckermanJan Tavernier

A1 Journal Article in BIOCHEMICAL JOURNAL

The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation

VM STUCKEEvy TimmermanJoël VandekerckhoveKris GevaertA HALL

A1 Journal Article in MOLECULAR BIOLOGY OF THE CELL

The transcriptional repressor Glis2 is a novel binding partner for p120 catenin

CR HOSKINGF ULLOAC HOGANEC FERBERA FIGUEROAKris GevaertW BIRCHMEIERJ BRISCOEY FUJITA

A1 Journal Article in MOLECULAR BIOLOGY OF THE CELL

Vaccination against Ostertagia ostertagi with subfractions of the protective ES-thiol fraction

Yves MeyvisPeter GeldhofKris GevaertEvy TimmermanJozef VercruysseEdwin Claerebout

A1 Journal Article in VETERINARY PARASITOLOGY

2006

A comparison of the HUPO Brain Proteome project pilot with other proteomics studies

Lennart MartensMichael MüllerChristian StephanMichael HamacherKai A ReidegeldHelmut E MeyerMartin BlüggelJoël VandekerckhoveKris GevaertRolf Apweiler

A1 Journal Article in PROTEOMICS

A complex interaction pattern of CIS and SOCS2 with the leptin receptor

Delphine LavensTony MontoyeJulie PiessevauxLennart ZabeauJoël VandekerckhoveKris GevaertW BECKERSven EyckermanJan Tavernier

A1 Journal Article in JOURNAL OF CELL SCIENCE

A new functional, chemical proteomics technology to identify purine nucleotide binding sites in complex proteomes

Xavier HanoulleJozef Van DammeAn StaesLennart MartensMarc GoethalsJoël VandekerckhoveKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

A small heat shock protein of Ostertagia ostertagi: Stage-specific expression, heat inducibility, and protection trial

I VERCAUTERENV MAEREJozef VercruysseM STEVENSKris GevaertEdwin Claerebout

A1 Journal Article in JOURNAL OF PARASITOLOGY

Cell_motility : a cross-platform, open source application for the study of cell motion paths

Lennart MartensGeert MonsieurChristophe AmpeKris GevaertJoël Vandekerckhove

A1 Journal Article in BMC BIOINFORMATICS

Four stage liquid chromatographic selection of methionyl peptides for peptide-centric proteome analysis: the proteome of human multipotent adult progenitor cells

Kris GevaertJozef PinxterenHans DemolKoen HugelierAn StaesJozef Van DammeLennart MartensJoël Vandekerckhove

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Identification and characterization of immunogenic proteins of Mycoplasma genitalium

HF SVENSTRUPJS JENSENKris GevaertS BIRKELUNDG CHRISTIANSEN

A1 Journal Article in CLINICAL AND VACCINE IMMUNOLOGY

Improved tandem mass spectrometric characterization of 3-nitrotyrosine sites in peptides

Bart GhesquièreMarc GoethalsJozef Van DammeAn StaesEvy TimmermanJoël VandekerckhoveKris Gevaert

A1 Journal Article in RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Improving the reliability and throughput of mass spectrometry-based proteomics by spectrum quality filtering

Kristian FlikkaLennart MartensJoël VandekerckhoveKris GevaertIngvar Eidhammer

A1 Journal Article in PROTEOMICS

Protein processing and other modifications analyzed by diagonal peptide chromatography

Kris GevaertPetra Van DammeBart GhesquièreJoël Vandekerckhove

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Proteome-wide characterization of N-glycosylation events by diagonal chromatography

Bart GhesquièreJozef Van DammeLennart MartensJoël VandekerckhoveKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

2005

An aspartyl protease inhibitor of Ostertagia ostertagi: Molecular cloning, analysis of stage and tissue specific expression and vaccine trial

Veerle De MaereI VERCAUTERENKris GevaertJozef VercruysseEdwin Claerebout

A1 Journal Article in MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis

Petra Van DammeLennart MartensJozef Van DammeKoen HugelierAn StaesJoël VandekerckhoveKris Gevaert

A1 Journal Article in NATURE METHODS

DBToolkit: processing protein databases for peptide-centric proteomics

Lennart MartensJoël VandekerckhoveKris Gevaert

A1 Journal Article in BIOINFORMATICS

Diagonal reverse-phase chromatography applications in peptide-centric proteomics: ahead of catalogue-omics?

Kris GevaertPetra Van DammeLennart MartensJoël Vandekerckhove

A1 Journal Article in ANALYTICAL BIOCHEMISTRY

Do we want our data raw?: including binary mass spectrometry data in public proteomics data repositories

Lennart MartensAlexey I NesvizhskiiHenning HermjakobMarcin AdamskiGilbert S OmennJoël VandekerckhoveKris Gevaert

A1 Journal Article in PROTEOMICS

Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC

Kris GevaertAn StaesJozef Van DammeSara De GrootKoen HugelierHans DemolLennart MartensMarc GoethalsJoël Vandekerckhove

A1 Journal Article in PROTEOMICS

Identification by two-dimensional electrophoresis of a new adhesin expressed by a low-passaged strain of Mycoplasma bovis

A THOMASP LEPRINCEI DIZIERH BALLKris GevaertJozef Van DammeJ MAINILA LINDEN

A1 Journal Article in RESEARCH IN MICROBIOLOGY

Molecular analysis of astacin-like metalloproteases of Ostertagia ostertagi

Veerle De MaereIsabel VercauterenPeter GeldhofKris GevaertJozef VercruysseEdwin Claerebout

A1 Journal Article in PARASITOLOGY

Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera

Philip MeulemanLouis LibbrechtRita De VosBernard de HemptinneKris GevaertJoël VandekerckhoveTania RoskamsGeert Leroux-Roels

A1 Journal Article in HEPATOLOGY

PRIDE: the proteomics identifications database

Lennart MartensHenning HermjakobPhilip JonesMarcin AdamskiChris TaylorDavid StatesKris GevaertJoël VandekerckhoveRolf Apweiler

A1 Journal Article in PROTEOMICS

The human platelet proteome mapped by peptide-centric proteomics: a functional protein profile

Lennart MartensPetra Van DammeJozef Van DammeAn StaesEvy TimmermanBart GhesquièreGrégoire R ThomasJoël VandekerckhoveKris Gevaert

A1 Journal Article in PROTEOMICS

2004

Global differential non-gel proteomics by quantitative and stable labeling of tryptic peptides with oxygen-18

An StaesHans DemolJozef Van DammeLennart MartensJoël VandekerckhoveKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Reversible labeling of cysteine-containing peptides allows their specific chromatographic isolation for non-gel proteome studies

Kris GevaertBart GhesquièreAn StaesLennart MartensJozef Van DammeGrégoire ThomasJoël Vandekerckhove

A1 Journal Article in PROTEOMICS

The use of proteomics in the study of cell death

Xavier SaelensG VAN LOOKris GevaertJoël VandekerckhovePeter Vandenabeele

Bookchapter in When Cells Die II: A Comprehensive Evaluation of Apoptosis and Programmed Cell Death

Vaccination with an Ostertagia ostertagi polyprotein allergen protects calves against homologous challenge infection

Isabel VercauterenPeter GeldhofJozef VercruysseIris PeelaersWim Van Den BroeckKris GevaertEdwin Claerebout

A1 Journal Article in INFECTION AND IMMUNITY

2003

Activation-associated secreted proteins are the most abundant antigens in a host protective fraction from Ostertagia ostertagi

Peter GeldhofIsabel VercauterenKris GevaertAn StaesDP KNOXJoël VandekerckhoveJozef VercruysseEdwin Claerebout

A1 Journal Article in MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides

Kris GevaertMarc GoethalsLennart MartensJozef Van DammeAn StaesGrégoire ThomasJoël Vandekerckhove

A1 Journal Article in NATURE BIOTECHNOLOGY

IL-29 Is proteomics heading towards medicine?

Joël VandekerckhoveJozef Van DammeLennart MartensGrégoire ThomasAn StaesMarc GoethalsBart GhesquièreMagda PuypeHans DemolKris Gevaert

A2 Journal Article in PIGMENT CELL RESEARCH

Protein characterization: analytical approaches and applications to proteomics

Kris GevaertJoël Vandekerckhove

Bookchapter in Encyclopedia of the human genome.

2002

A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid

Geert van LooHans DemolMarjan Van GurpB HoorelbekePeter SchotteRudi BeyaertB ZhivotovskyKris GevaertWim DeclercqJoël Vandekerckhove et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

An ASP-like protein is the most abundant antigen in a host protective fraction from Ostertagia ostertagi

Peter GeldhofIsabel VercauterenKris GevaertA StaesD KnoxEdwin ClaereboutJoël VandekerckhoveJozef Vercruysse

Characterization of a secreted Chlamydia protease.

AC SHAWBB VANDAHLMR LARSENP ROEPSTORFFKris GevaertJoël VandekerckhoveG CHRISTIANSENS BIRKELUND

A1 Journal Article in CELLULAR MICROBIOLOGY

Chromatographic isolation of methionine-containing peptides for gel-free proteome analysis: identification of more than 800 Escherichia coli proteins

Kris GevaertJozef Van DammeMarc GoethalsGrégoire ThomasBart HoorelbekeHans DemolLennart MartensMagda PuypeAn StaesJoël Vandekerckhove

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Comparative proteome analysis of Chlamydia trachomatis serovar A, D and L2.

AC SHAWKris GevaertHans DemolB HOORELBEKEJoël VandekerckhoveMR LARSENP ROEPSTORFFA HOLMG CHRISTIANSENS BIRKELUND

A1 Journal Article in PROTEOMICS

The calcium-binding protein p54/NEFA is a novel luminal resident of medial Golgi cisternae that traffics independently of mannosidase II

Valérie M Morel-HuauxMarc PypaertSandrine WoutersAlan M TartakoffUlrich JurganKris GevaertPierre J Courtoy

A1 Journal Article in EUROPEAN JOURNAL OF CELL BIOLOGY

The expression, processing and localization of polymorphic membrane proteins in Chlamydia pneumoniae strain CWL029.

BB VANDAHLAS PEDERSENKris GevaertA HOLMJoël VandekerckhoveG CHRISTIANSENS BIRKELUND

A1 Journal Article in BMC MICROBIOLOGY

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity.

Geert van LooMarjan Van GurpBart DepuydtSM SRINIVASULAI RODRIGUEZES ALNEMRIKris GevaertJoël VandekerckhoveWim DeclercqPeter Vandenabeele

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methyl glyoxal-derived AGE.

Franky Van HerrewegheJQ MAOF CHAPLENJohan GrootenKris GevaertJoël VandekerckhoveKatia Vancompernolle

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2001

A novel receptor-mediated regulation mechanism of type I inositol polyphosphate 5-phosphatase by calcium/calmodulindependent protein kinase II phosphorylation.

D COMMUNIKris GevaertHans DemolJoël VandekerckhoveC ERNEUX

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Cdc42 induces filopodia by promoting the formation of an IRSp53: Mena complex.

S KRUGMANNI JORDENSKris GevaertM DRIESSENSJoël VandekerckhoveA HALL

A1 Journal Article in CURRENT BIOLOGY

Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspaseindependent DNA degradation

Geert van LooPeter SchotteMarjan Van GurpHans DemolB HOORELBEKEKris GevaertI RODRIGUEZA RUIZ-CARRILLOJoël VandekerckhoveWim Declercq et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Protein identification based on matrix assisted laser desorption/ionization-post source decay-mass spectrometry.

Kris GevaertHans DemolLennart MartensB HOORELBEKEMagda PuypeM GOETHALSJozef Van DammeStefaan De BoeckJoël Vandekerckhove

A1 Journal Article in ELECTROPHORESIS

Proteome analysis of the Chlamydia pneumoniae elementary body.

BB VANDAHLS BIRKELUNDHans DemolB HOORELBEKEG CHRISTIANSENJoël VandekerckhoveKris Gevaert

A1 Journal Article in ELECTROPHORESIS

Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16.

H DAUBKris GevaertJoël VandekerckhoveA SOBELA HALL

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Time-dependent expression and processing of a hypothetical protein of possible importance for regulation of the Chlamydia pneumoniae developmental cycle.

BB VANDAHLKris GevaertHans DemolB HOORELBEKEA HOLMJoël VandekerckhoveG CHRISTIANSENS BIRKELUND

A1 Journal Article in ELECTROPHORESIS

2000

A fast and convenient MALDI-MS based proteomic approach: identification of components scaffolded by the actin cytoskeleton of activated human thrombocytes.

Kris GevaertL EGGERMONTHans DemolJoël Vandekerckhove

A1 Journal Article in JOURNAL OF BIOTECHNOLOGY

A plant plasma membrane H+-ATPase expressed in yeast is activated by phosphorylation at its penultimate residue and binding of 14-3-3 regulatory proteins in the absence of fusicoccin.

O MAUDOUXH BATOKOC OECKINGKris GevaertJoël VandekerckhoveM BOUTRYP MORSOMME

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Protein identification methods in proteomics.

Kris GevaertJoël Vandekerckhove

A1 Journal Article in ELECTROPHORESIS

Targeting of aminopeptidase I to the yeast vacuole ts mediated by Ssa1p, a cytosolic member of the 70-kDa stress protein family.

E SILLESMJ MAZONKris GevaertM GOETHALSJoël VandekerckhoveR LEBERIV SANDOVAL

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Techniques for sample preparation including methods for concentrating peptide samples

Kris GevaertTony HouthaeveJoël Vandekerckhove

Bookchapter in Proteomics in functional genomics : protein structure analysis

1998

A peptide concentration and purification method for protein characterization in the subpicomole range using matrix assisted laser desorption/ionization postsource decay (MALDI-PSD) sequencing

Kris GevaertHans DemolTatyana SklyarovaJoël VandekerckhoveT HOUTHAEVE

A1 Journal Article in ELECTROPHORESIS

Sample preparation procedures for ultrasensitive protein identification by PSD-MALDI-TOF mass spectrometry

Kris GevaertH DE MOLMagda PuypeT HOUTHAEYEStefaan De BoeckJ VANDEKERCHKHOVE

A1 Journal Article in JOURNAL OF PROTEIN CHEMISTRY

1997

Novel techniques for identification and characterization of proteins loaded on gels in femtomole amounts.

Kris GevaertHans DemolJean-Luc VerscheldeJ VANDAMMES DEBOECKJoël Vandekerckhove

A1 Journal Article in JOURNAL OF PROTEIN CHEMISTRY

Peptides adsorbed on reverse-phase chromatographic beads as targets for femtomole sequencing by post-source decay matrix assisted laser desorption ionization-reflectron time of flight mass spectrometry (MALDI-RETOF-MS).

Kris GevaertHans DemolMagda PuypeDaniël BroekaertStefaan De BoeckTony HouthaeveJoël Vandekerckhove

A1 Journal Article in ELECTROPHORESIS

1996

Structural analysis and identification of gel-purified proteins, available in the femtomole range, using a novel computer program for peptide sequence assignment, by matrix-assisted laser desorption ionization reflectron time-of-flight mass spectrometry.

Kris GevaertJL VERSCHELDEMagda PuypeJ VANDAMMEM GOETHALSS DEBOECKJoël Vandekerckhove

A1 Journal Article in ELECTROPHORESIS

1995

An agarose-based gel-concentration system for microsequence and mass spectrometric characterization of proteins previously purified in polyacrylamide gels starting at low picomole levels.

MH RIDERMagda PuypeJ VANDAMMEKris GevaertS DEBOECKJ DALAYERHH RASMUSSENJE CELISJoël Vandekerckhove

A1 Journal Article in EUROPEAN JOURNAL OF BIOCHEMISTRY