Photolithographic DNA printer for massively parallel synthesis of DNA oligonucleotides for spatial - omics and hybrid capture target enrichment applications

6-color digital PCR instrument

Advancing Liquid Biopsies for Monitoring and Personalized Treatment of Children with Neuroblastoma

Bioinformatics: from nucleotids to networks (N2N)

BOF-ZAP professorship in functional genomics and genomic bio-computing

Cell-free nucleic acid profiling in diffuse large B-cell lymphoma: a molecular guidance to precision medicine

Cell-free nucleic acid profiling in diffuse large B-cell lymphoma: a molecular guidance to precision medicine

Center for Bioassay Development and Screening (C-BIOS)

Charting the long non-coding RNA landscape in cancer: from gene alterations to functions

Circulating tumor-derived RNA biomarkers: from bench to bedside

Deciphering the molecular pathogenesis of neuroblastoma through next generation genome analysis

Decoding long non-coding RNAs in cancer - Foundation against cancer

Developing technology to facilitate high-throughput (real time) PCR applications (Type 1)

Development and application of digital PCR

Development of a laboratory toolbox to study human circular RNAs

Development of high-throughput technologies for functional genomics

Development of methods for the quantification of nucleic acids in functional genomics in cancer

Discovery and functional analysis of TP53 network long non-coding RNA genes in cancer

Disentangeling of Myc interaction networks by integrated genome-wide bioinformatic analysis of high-throughput transcriptomic and ChIP data.

Elucidation and functional analysis of lncRNA variation and TP53 associated lncRNAs in neuroblastoma

Fair Anneleen Decock: Pioneering the neuroblastoma DNA methylome: identify biological differences between subgroups and optimization biomerkerdetectie plasma.

Genome wide study of mutations in murine neuroblastoma models

Genomic and transcriptoomproflering neuroblastoma: identification of prognostic diagnostic expression signatures, unraveling the MYCN transcriptional network and study of the biological role v chromosome 17q gain..

Harnessing a xenograft rat model to illuminate tumor-derived extracellular RNA in liquid biopsies

Human exome resequencing PCR assay design

Identification and functional characterisation of non-coding RNAs in cancer

Identification of candidate therapeutic long non-coding RNA genes in the pathway TP53

Improved Outcome Prediction of Children with Neuroblastoma using a Mutigene Expression Signature

Improved outcome prediction of children with neuroblastoma using an integrated m/miRNA and DNA methylation signature (Stichting tegen Kanker)

Integrated biology-driven diagnostic and therapeutic management of neuroblastoma (Stichting tegen Kanker)

Integration of miRNAs and long non-coding RNAs in the molecular circuitry of neuroblastoma tumors

International Thematic Network - PrIOMIC 2023-2024

Investigation of the ARF/MDM2/p53 signaling pathway in cancer cells by means of miRNA analysis and RNA interference screening

LncRNAs as therapeutic targets and diagnostic biomarkers for advanced melanoma

Long noncoding RNAs in cancer: deciphering the functional role of the dark matter of the human cancer genome

Long noncoding RNAs in cancer: deciphering the functional role of the dark matter of the human cancer genome

miRNA - Chemoresistance

Molecular phenotyping and in vivo assessment of miRNA perturbation in neuroblastoma

Molecular phenotyping of genome-wide miRNA perturbation in neuroblastoma

Multi Gene expression signatures for accurate risk stratification of neuroblastoma patients

Multilevel biomarker assessment in children with neuroblastoma: perspectives for improved outcome prediction and therapy

Multilevel functional characterization of the miRNome in cancer (Kom op tegen Kanker)

Pan-cancer liquid biopsy screening for the identification of actionable RNA biomarkers

Prostate cancer patient exosomes: where do they come from and where are they going?

Replication fork protector dependency factors: novel targets for combination treatment and immunomodulation in neuroblastoma (REINFORCE)

scientific assignment Hetty Helsmoortel

Selective resequencing of miRNA genes in neuroblastoma

The biology of tumor-derived extracellular RNA in liquid biopsies

Therapeutic application of SAMMSON lncRNA inhibition in ocular melanoma and non-melanoma tumors

Therapeutic restoration of p53 function in neuroblastoma

The role of RNA in cancer

Tumor and its microenvironment as a reference for therapy response evaluation

Unraveling the 17q enigma in neuroblastoma: from functional genomics to molecular therapy

Unraveling the MYC cancer IncRNA network

Validation of candidate TP53-lncRNAs using a high-throughput shRNA screening

Analyzing circulating bacterial extracellular vesicles in cancer patients to identify their composition and biomarker potential.

Cancer-specific circulating RNAs as biomarkers for diagnosis and therapy response monitoring

Cancer-specific circulating RNAs as biomarkers for diagnosis and therapy response monitoring.

Characterization of the p53 network and exploration of p53-dependent and p53-independent molecular therapy in neuroblastoma

Every cell counts! Transforming exercise science through single fiber transcriptome analysis in human skeletal muscle

Genome wide screening for methylation defects, nonsense mutaions and tumour-related microRNA expression profiles in neuroblastoma

Integrated molecular profiling in neuroblastoma: identification of new molecular therapeutic targets and optimalised prognostic classification

Interrelationship of pulmonary inflammation, systemic inflammation and airway remodelling in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD).

Reconstruction of functional molecular networks in ALK mutated neuroblastomas

Reprogramming of tumor-associated dendritic cells on microRNA level as a novel immune escape mechanism in cancer

STAND UP TO CANCER: Integration of individual cancer genes in signalisation network in pediatric tumors

The first genome-wide maps of the micropeptidome validated through large-scale reprocessing of public proteomics data

The role of miRNAs during bovine preimplantation development

ThirdGenT: linking third-generation sequencing of (epi)genomes, (epi)transcriptomes and translatomes to life sciences revolutionizes oncology, rare diseases, microbiology, cell and gene technology, developmental and computational biology

BOF-ZAP professorship in functional genomics and genomic bio-computing

Genomic and transcriptoomproflering neuroblastoma: identification of prognostic diagnostic expression signatures, unraveling the MYCN transcriptional network and study of the biological role v chromosome 17q gain..

Improving multiplex digital PCR based nucleic acid quantification using data driven analysis tools