Development of methods for the quantification of nucleic acids in functional genomics in cancer

International thematic network - PrIOMIC

6-color digital PCR instrument

Cell-free nucleic acid profiling in diffuse large B-cell lymphoma: a molecular guidance to precision medicine

Cell-free nucleic acid profiling in diffuse large B-cell lymphoma: a molecular guidance to precision medicine

Replication fork protector dependency factors: novel targets for combination treatment and immunomodulation in neuroblastoma (REINFORCE)

Development of a laboratory toolbox to study human circular RNAs

The biology of tumor-derived extracellular RNA in liquid biopsies

Advancing Liquid Biopsies for Monitoring and Personalized Treatment of Children with Neuroblastoma

Pan-cancer liquid biopsy screening for the identification of actionable RNA biomarkers

Circulating tumor-derived RNA biomarkers: from bench to bedside

ZAP post in functional genomics and genomic bio-computing

Center for Bioassay Development and Screening (C-BIOS)

Prostate cancer patient exosomes: where do they come from and where are they going?

Therapeutic application of SAMMSON lncRNA inhibition in ocular melanoma and non-melanoma tumors

scientific assignment Hetty Helsmoortel

miRNA - Chemoresistance

Identification and functional characterisation of non-coding RNAs in cancer

Long noncoding RNAs in cancer: deciphering the functional role of the dark matter of the human cancer genome

Long noncoding RNAs in cancer: deciphering the functional role of the dark matter of the human cancer genome

Fair Anneleen Decock: Pioneering the neuroblastoma DNA methylome: identify biological differences between subgroups and optimization biomerkerdetectie plasma.

Decoding long non-coding RNAs in cancer - Foundation against cancer

Validation of candidate TP53-lncRNAs using a high-throughput shRNA screening

Elucidation and functional analysis of lncRNA variation and TP53 associated lncRNAs in neuroblastoma

Therapeutic restoration of p53 function in neuroblastoma

LncRNAs as therapeutic targets and diagnostic biomarkers for advanced melanoma

Identification of candidate therapeutic long non-coding RNA genes in the pathway TP53

Multilevel functional characterization of the miRNome in cancer (Kom op tegen Kanker)

Charting the long non-coding RNA landscape in cancer: from gene alterations to functions

Improved outcome prediction of children with neuroblastoma using an integrated m/miRNA and DNA methylation signature (Stichting tegen Kanker)

Integrated biology-driven diagnostic and therapeutic management of neuroblastoma (Stichting tegen Kanker)

Unraveling the MYC cancer IncRNA network

Discovery and functional analysis of TP53 network long non-coding RNA genes in cancer

Genome wide study of mutations in murine neuroblastoma models

Tumor and its microenvironment as a reference for therapy response evaluation

Development and application of digital PCR

Human exome resequencing PCR assay design

Integration of miRNAs and long non-coding RNAs in the molecular circuitry of neuroblastoma tumors

Molecular phenotyping and in vivo assessment of miRNA perturbation in neuroblastoma

Deciphering the molecular pathogenesis of neuroblastoma through next generation genome analysis

Disentangeling of Myc interaction networks by integrated genome-wide bioinformatic analysis of high-throughput transcriptomic and ChIP data.

Bioinformatics: from nucleotids to networks (N2N)

Selective resequencing of miRNA genes in neuroblastoma

Molecular phenotyping of genome-wide miRNA perturbation in neuroblastoma

Improved Outcome Prediction of Children with Neuroblastoma using a Mutigene Expression Signature

Multilevel biomarker assessment in children with neuroblastoma: perspectives for improved outcome prediction and therapy

Multi Gene expression signatures for accurate risk stratification of neuroblastoma patients

Investigation of the ARF/MDM2/p53 signaling pathway in cancer cells by means of miRNA analysis and RNA interference screening

Developing technology to facilitate high-throughput (real time) PCR applications (Type 1)

Unraveling the 17q enigma in neuroblastoma: from functional genomics to molecular therapy

Development of high-throughput technologies for functional genomics

Genomic and transcriptoomproflering neuroblastoma: identification of prognostic diagnostic expression signatures, unraveling the MYCN transcriptional network and study of the biological role v chromosome 17q gain..

Every cell counts! Transforming exercise science through single fiber transcriptome analysis in human skeletal muscle

Analyzing circulating bacterial extracellular vesicles in cancer patients to identify their composition and biomarker potential.

Cancer-specific circulating RNAs as biomarkers for diagnosis and therapy response monitoring

The first genome-wide maps of the micropeptidome validated through large-scale reprocessing of public proteomics data

Cancer-specific circulating RNAs as biomarkers for diagnosis and therapy response monitoring.

Reconstruction of functional molecular networks in ALK mutated neuroblastomas

Reprogramming of tumor-associated dendritic cells on microRNA level as a novel immune escape mechanism in cancer

STAND UP TO CANCER: Integration of individual cancer genes in signalisation network in pediatric tumors

Characterization of the p53 network and exploration of p53-dependent and p53-independent molecular therapy in neuroblastoma

The role of miRNAs during bovine preimplantation development

Interrelationship of pulmonary inflammation, systemic inflammation and airway remodelling in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD).

Integrated molecular profiling in neuroblastoma: identification of new molecular therapeutic targets and optimalised prognostic classification

Genome wide screening for methylation defects, nonsense mutaions and tumour-related microRNA expression profiles in neuroblastoma

ZAP post in functional genomics and genomic bio-computing

Genomic and transcriptoomproflering neuroblastoma: identification of prognostic diagnostic expression signatures, unraveling the MYCN transcriptional network and study of the biological role v chromosome 17q gain..

Improving multiplex digital PCR based nucleic acid quantification using data driven analysis tools