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Researcher
Jo Vandesompele
Profile
Projects
Publications
Activities
548
Results
2022
Blocking unwanted sequences by target specific high-affinity binding oligonucleotides during transcriptome library preparation
Celine Everaert
Jasper Verwilt
Kimberly Verniers
Niels Vandamme
Alvaro Marcos Rubio
Jo Vandesompele
Pieter Mestdagh
Preprint
2022
CIRCprimerXL : convenient and high-throughput PCR primer design for circular RNA quantification
Marieke Vromman
Jasper Anckaert
Jo Vandesompele
Pieter-Jan Volders
A2
Journal Article
in
FRONTIERS IN BIOINFORMATICS
2022
CiLiQuant : quantification of RNA junction reads based on their circular or linear transcript origin
Annelien Morlion
Eva Hulstaert
Marieke Vromman
Jasper Anckaert
Celine Everaert
Jo Vandesompele
Pieter Mestdagh
A2
Journal Article
in
FRONTIERS IN BIOINFORMATICS
2022
Comprehensive RNA dataset of tissue and plasma from patients with esophageal cancer or precursor lesions
Kathleen Schoofs
Annouck Philippron
Francisco Avila Cobos
Steve Lefever
Jasper Anckaert
Danny De Looze
Jo Vandesompele
Piet Pattyn
Katleen De Preter
A1
Journal Article
in
SCIENTIFIC DATA
2022
Evaluation of efficiency and sensitivity of 1D and 2D sample pooling strategies for SARS-CoV-2 RT-qPCR screening purposes
Jasper Verwilt
Tom Sante
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
SCIENTIFIC REPORTS
2022
Nucleic acid biomarkers in Waldenstrom Macroglobulinemia and IgM-MGUS : current insights and clinical relevance
Philippe Decruyenaere
Fritz Offner
Jo Vandesompele
A1
Journal Article
in
DIAGNOSTICS
2022
RNA biomarkers from proximal liquid biopsy for diagnosis of ovarian cancer
Eva Hulstaert
Annelien Morlion
Jasper Anckaert
Kimberly Verniers
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
NEOPLASIA
2022
Reliable and scalable SARS-CoV-2 qPCR testing at a high sample throughput : lessons learned from the Belgian initiative
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
LIFE-BASEL
2022
The adrenergic-specific long non-coding RNA NESPR controls survival of neuroblastoma cells
Louis Delhaye
Eric de Bony de Lavergne
Dries Rombaut
Bieke Decaesteker
Lisa Depestel
Amber Louwagie
Eva D'haene
Pieter-Jan Volders
Nurten Yigit
Delphine De Sutter
Jasper Anckaert
Sarah-Lee Bekaert
Celine Everaert
Björn Menten
Jo Vandesompele
Steve Lefever
Franki Speleman
Sven Eyckerman
Pieter Mestdagh
C3
Conference
2022
The dangers of using Cq to quantify nucleic acid in biological samples : a lesson from COVID-19
Jasper Verwilt
Jo Vandesompele
A1
Journal Article
in
CLINICAL CHEMISTRY
2022
The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival
Shanna Dewaele
Louis Delhaye
Boel De Paepe
Eric de Bony de Lavergne
Jilke De Wilde
Katrien Vanderheyden
Jasper Anckaert
Nurten Yigit
Justine Nuytens
Eveline Vanden Eynde
Joél Smet
Maxime Verschoore
Jo Vandesompele
Jo Van Dorpe
Rudy Van Coster
Sven Eyckerman
Pieter Mestdagh
A1
Journal Article
in
ONCOGENE
2022
The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival (Sept, 10.1038/s41388-021-02006-x, 2021)
Shanna Dewaele
Louis Delhaye
Boel De Paepe
Jilke De Wilde
Katrien Vanderheyden
Jasper Anckaert
Nurten Yigit
Justine Nuytens
Eveline Vanden Eynde
Joél Smet
Maxime Verschoore
Jo Vandesompele
Jo Van Dorpe
Jean-Christophe Marine
Rudy Van Coster
Sven Eyckerman
Pieter Mestdagh
Correction
2022
Transient nuclear lamin A/C accretion aids in recovery from vapor nanobubble-induced permeabilisation of the plasma membrane
Gaëlle Houthaeve
Stephan Stremersch
Herlinde De Keersmaecker
Juan Fraire
Jo Vandesompele
Pieter Mestdagh
Stefaan De Smedt
Kevin Braeckmans
Winnok De Vos
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2022
Unraveling the therapeutic potential of SAMMSON lncRNA inhibition in uveal melanoma
Shanna Dewaele
Pieter Mestdagh
Jo Vandesompele
Dissertation
2022
When DNA gets in the way in RNA-seq experiments, a sequel
Jasper Verwilt
Wim Trypsteen
Ruben Van Paemel
Katleen De Preter
Pieter Mestdagh
Jo Vandesompele
Preprint
2022
mRNA capture sequencing and RT-qPCR for the detection of pathognomonic, novel, and secondary fusion transcripts in FFPE tissue : a sarcoma showcase
Anneleen Decock
David Creytens
Steve Lefever
Joni Van der Meulen
Jasper Anckaert
Jill Deleu
Bram De Wilde
Isabelle Rottiers
Katrien Vanderheyden
Eveline Vanden Eynde
Kimberly Verniers
Jo Van Dorpe
Jo Vandesompele
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
2021
A G316A polymorphism in the ornithine decarboxylase gene promoter modulates MYCN-driven childhood neuroblastoma
Ali Rihani
Tom Van Maerken
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
CANCERS
2021
Candidate RNA biomarkers in biofluids for early diagnosis of ovarian cancer : a systematic review
Eva Hulstaert
Annelien Morlion
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
GYNECOLOGIC ONCOLOGY
2021
Charting regulatory RNAs in the human transcriptome using RNA-sequencing
Lucia Lorenzi
Pieter Mestdagh
Jo Vandesompele
Dissertation
2021
Circulating RNA biomarkers in diffuse large B-cell lymphoma : a systematic review
Philippe Decruyenaere
Fritz Offner
Jo Vandesompele
A1
Journal Article
in
EXPERIMENTAL HEMATOLOGY & ONCOLOGY
2021
Circulating bacterial vesicles : from discovery towards clinical application
Joeri Tulkens
An Hendrix
Jo Vandesompele
Dissertation
2021
Closing the circle : current state and perspectives of circular RNA databases
Marieke Vromman
Jo Vandesompele
Pieter-Jan Volders
A1
Journal Article
in
BRIEFINGS IN BIOINFORMATICS
2021
Custom long non-coding RNA capture enhances detection sensitivity in different human sample types
Annelien Morlion
Celine Everaert
Justine Nuytens
Eva Hulstaert
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
RNA BIOLOGY
2021
Evaluating diagnostic accuracy of saliva sampling methods for severe acute respiratory syndrome coronavirus 2 reveals differential sensitivity and association with viral load
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
JOURNAL OF MOLECULAR DIAGNOSTICS
2021
Exploring RNA signatures in human biofluids as novel liquid biopsy tool
Eva Hulstaert
Pieter Mestdagh
Lieve Brochez
Jo Vandesompele
Dissertation
2021
Genome-wide study of the effect of blood collection tubes on the cell-free DNA methylome
Ruben Van Paemel
Andries De Koker
Annelien Morlion
Pieter Mestdagh
Bram De Wilde
Jo Vandesompele
Katleen De Preter
A1
Journal Article
in
EPIGENETICS
2021
MISpheroID : a knowledgebase and transparency tool for minimum information in spheroid identity
Arne Peirsman
Eva Blondeel
Jasper Anckaert
Dominique Audenaert
Tom Boterberg
Elly De Vlieghere
Sandor Dedeyne
Herman Depypere
Ruslan Dmitriev
Suzanne Fischer
Vera Goossens
An Hendrix
Sebastiaan Maes
Christophe Mangodt
Pieter Mestdagh
Cláudio Pinheiro
Gwen Sys
Joeri Tulkens
Jo Vandesompele
Glenn Wagemans
Nurten Yigit
Phillip Blondeel
Olivier De Wever
A1
Journal Article
in
NATURE METHODS
2021
Messenger RNA capture sequencing of extracellular RNA from human biofluids using a comprehensive set of spike-in controls
Eva Hulstaert
Anneleen Decock
Annelien Morlion
Celine Everaert
Kimberly Verniers
Justine Nuytens
Pieter Mestdagh
Jo Vandesompele
A2
Journal Article
in
STAR PROTOCOLS
2021
Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA : a proof-of-principle study
Ruben Van Paemel
Andries De Koker
Charlotte Vandeputte
Tim Lammens
Genevieve Laureys
Jo Vandesompele
Nadine Van Roy
Nico Callewaert
Katleen De Preter
Bram De Wilde
A1
Journal Article
in
EPIGENETICS
2021
Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions
Liselot Mus
Stéphane Van Haver
Mina Popovic
Wim Trypsteen
Steve Lefever
Eva Jacobs
Ellen Sanders
Christophe Van Neste
Suzanne Vanhauwaert
Bieke Decaesteker
Dieter Deforce
Filip Van Nieuwerburgh
Pieter Mestdagh
Jo Vandesompele
Björn Menten
Katleen De Preter
Björn Heindryckx
Kaat Durinck
Franki Speleman
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2021
Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions
Glenn Vergauwen
Joeri Tulkens
Cláudio Pinheiro
Francisco Avila Cobos
Sandor Dedeyne
Marie-Angélique De Scheerder
Linos Vandekerckhove
Francis Impens
Geert Braems
Kris Gevaert
Pieter Mestdagh
Jo Vandesompele
Hannelore Denys
Olivier De Wever
An Hendrix
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2021
Selection and validation of reference genes for accurate RT-qPCR gene expression normalization in cacao beans during fermentation
Jocelyn De Wever
Tibo De Coninck
Helena Everaert
Frauke Coppieters
Hayley Rottiers
Koen Dewettinck
Jo Vandesompele
Steve Lefever
Kathy Messens
A1
Journal Article
in
TREE GENETICS & GENOMES
2021
Targeted therapy of TERT-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2021
The MicroRNA landscape of acute beta cell destruction in type 1 diabetic recipients of intraportal islet grafts
Geert Martens
Jasper Anckaert
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
CELLS
2021
The RNA Atlas expands the catalog of human non-coding RNAs
Lucia Lorenzi
Francisco Avila Cobos
Pieter-Jan Volders
Robrecht Cannoodt
Justine Nuytens
Katrien Vanderheyden
Jasper Anckaert
Steve Lefever
Wim Trypsteen
Fien Gysens
Marieke Vromman
Tine Goovaerts
Nele Nijs
Tom Taghon
Karim Vermaelen
Ken Bracke
Yvan Saeys
Tim De Meyer
Katleen De Preter
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2021
The RNA Atlas expands the catalog of human non-coding RNAs (June, 10.1038/s41587-021-00936-1, 2021)
Francisco Avila Cobos
Pieter-Jan Volders
Robrecht Cannoodt
Justine Nuytens
Jasper Anckaert
Steve Lefever
Wim Trypsteen
Fien Gysens
Marieke Vromman
Tom Taghon
Karim Vermaelen
Ken Bracke
Yvan Saeys
Tim De Meyer
Katleen De Preter
Jo Vandesompele
Pieter Mestdagh
Correction
2021
2020
Cautionary note on contamination of reagents used for molecular detection of SARS-CoV-2
Jo Vandesompele
A1
Journal Article
in
CLINICAL CHEMISTRY
2020
Charting extracellular transcriptomes in the human biofluid RNA atlas
Eva Hulstaert
Annelien Morlion
Francisco Avila Cobos
Kimberly Verniers
Justine Nuytens
Eveline Vanden Eynde
Nurten Yigit
Jasper Anckaert
Anja Geerts
Pieter Hindryckx
Peggy Jacques
Guy Brusselle
Ken Bracke
Tania Maes
Caroline Van Cauwenbergh
Kristien Roelens
Ellen Roets
Dimitri Hemelsoet
Kelly Tilleman
Lieve Brochez
Steve Lefever
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
CELL REPORTS
2020
Development of extracellular RNA sequencing technologies and applications for cancer diagnosis and monitoring
Celine Everaert
Pieter Mestdagh
Jo Vandesompele
Dissertation
2020
Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development
Anne-Catherine Dolens
Kaat Durinck
Marieke Lavaert
Joni Van der Meulen
Imke Velghe
Jelle De Medts
Karin Weening
Juliette Roels
Katrien De Mulder
Pieter-Jan Volders
Katleen De Preter
Tessa Kerre
Bart Vandekerckhove
Georges Leclercq
Jo Vandesompele
Pieter Mestdagh
Pieter Van Vlierberghe
Franki Speleman
Tom Taghon
A1
Journal Article
in
EMBO REPORTS
2020
Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction
Joeri Tulkens
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Bert Dhondt
Lien Lippens
Marie-Angélique De Scheerder
Bruno De Geest
Katrien Vandecasteele
Debby Laukens
Linos Vandekerckhove
Hannelore Denys
Jo Vandesompele
Olivier De Wever
An Hendrix
A1
Journal Article
in
GUT
2020
Localization and expression of nuclear factor of activated T-cells 5 in myoblasts exposed to pro-inflammatory cytokines or hyperosmolar stress and in biopsies from myositis patients
dr. Sandrine Herbelet
Elly De Vlieghere
Amanda Gonçalves
Boel De Paepe
Gert Van Peer
Jo Vandesompele
Olivier De Wever
Jan De Bleecker
Bookchapter
in
Myokines, adipokines, cytokines in muscle pathophysiology
2020
Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA
Ruben Van Paemel
Andries De Koker
Charlotte Vandeputte
Tim Lammens
Genevieve Laureys
Jo Vandesompele
Nadine Van Roy
Nico Callewaert
Bram De Wilde
Katleen De Preter
C3
Conference
2020
On the utility of RNA sample pooling to optimize cost and statistical power in RNA sequencing experiments
Alemu Takele Assefa
Jo Vandesompele
Olivier Thas
A1
Journal Article
in
BMC GENOMICS
2020
Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles
Celine Everaert
Hetty Helsmoortel
Anneleen Decock
Eva Hulstaert
Ruben Van Paemel
Kimberly Verniers
Justine Nuytens
Jasper Anckaert
Joeri Tulkens
Bert Dhondt
An Hendrix
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2020
SPsimSeq : semi-parametric simulation of bulk and single-cell RNA-sequencing data
Alemu Takele Assefa
Jo Vandesompele
Olivier Thas
A1
Journal Article
in
BIOINFORMATICS
2020
Statistical methods for testing differential gene expression in bulk and single-cell RNA sequencing data
Alemu Takele Assefa
Olivier Thas
Jo Vandesompele
Dissertation
2020
Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control study-important considerations for liquid biopsies
Anneleen Decock
Jasper Anckaert
Celine Everaert
Justine Nuytens
An Hendrix
Jo Vandesompele
Pieter Mestdagh
Bert Dhondt
Ruben Van Paemel
Kimberly Verniers
Nurten Yigit
Kathleen Schoofs
Annelien Morlion
Jill Deleu
Eva Hulstaert
Francisco Avila Cobos
Eveline Vanden Eynde
Hetty Helsmoortel
Olivier De Wever
Annouck Philippron
C3
Conference
2020
The digital MIQE guidelines update : minimum information for publication of quantitative digital PCR experiments for 2020
Ward De Spiegelaere
Jo Vandesompele
A1
Journal Article
in
CLINICAL CHEMISTRY
2020
Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis
Juan Fraire
Gaëlle Houthaeve
Jing Liu
Laurens Raes
Lotte Vermeulen
Stephan Stremersch
Toon Brans
Sarah De Keulenaer
Filip Van Nieuwerburgh
Riet De Rycke
Jo Vandesompele
Pieter Mestdagh
Koen Raemdonck
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2020
When DNA gets in the way : a cautionary note for DNA contamination in extracellular RNA-seq studies
Jasper Verwilt
Wim Trypsteen
Ruben Van Paemel
Katleen De Preter
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2020
2019
Benchmarking the impact of data transformation, pre-processing and choice of method in the computational deconvolution of transcriptomics data
Francisco Avila Cobos
Jo Vandesompele
Pieter Mestdagh
Katleen De Preter
C3
Conference
2019
Cost-effective and robust genotyping using double-mismatch allele-specific quantitative PCR
Steve Lefever
Ali Rihani
Joni Van der Meulen
Filip Pattyn
Tom Van Maerken
Jo Van Dorpe
Jo Vandesompele
A1
Journal Article
in
SCIENTIFIC REPORTS
2019
Deciphering complete cancer transcriptomes from bulk to single cell level
Karen Verboom
Franki Speleman
Jo Vandesompele
Kaat Durinck
Dissertation
2019
Discovery and validation of a serum microRNA signature to characterize oligo- and polymetastatic prostate cancer : not ready for prime time
Bert Dhondt
Elise De Bleser
Tom Claeys
Sarah Buelens
Nicolaas Lumen
Jo Vandesompele
Valerie Fonteyne
Kim Van der Eecken
Aurélie De Bruycker
Piet Ost
A1
Journal Article
in
WORLD JOURNAL OF UROLOGY
2019
Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies
Annelien Morlion
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Olivier De Wever
Bert Dhondt
Celine Everaert
Hetty Helsmoortel
An Hendrix
Eva Hulstaert
Pieter Mestdagh
Justine Nuytens
Annouck Philippron
Eveline Vanden Eynde
Jo Vandesompele
Ruben Van Paemel
Kimberly Verniers
Nurten Yigit
C3
Conference
2019
Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies
Annelien Morlion
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Olivier De Wever
Bert Dhondt
Celine Everaert
Hetty Helsmoortel
An Hendrix
Eva Hulstaert
Pieter Mestdagh
Justine Nuytens
Annouck Philippron
Eveline Vanden Eynde
Jo Vandesompele
Ruben Van Paemel
Kimberly Verniers
Nurten Yigit
C3
Conference
2019
Effect of methylprednisolone on NFAT5 in Duchenne muscular dystrophy fibroblasts
dr. Sandrine Herbelet
Amanda Gonçalves
Jo Vandesompele
Jan De Bleecker
C3
Conference
2019
Evaluating the applicability of mouse SINEs as an alternative normalization approach for RT-qPCR in brain tissue of the APP23 model for Alzheimer’s disease
René Crans
Kathleen Van Craenenbroeck
Jo Vandesompele
Christophe Stove
A1
Journal Article
in
JOURNAL OF NEUROSCIENCE METHODS
2019
Evaluating the impact of RNA purification kit and blood collection tube in the extracellular RNA quality control study : important considerations for liquid biopsies
Annelien Morlion
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Jill Deleu
Olivier De Wever
Bert Dhondt
Celine Everaert
Hetty Helsmoortel
An Hendrix
Eva Hulstaert
Pieter Mestdagh
Justine Nuytens
Annouck Philippron
Kathleen Schoofs
Eveline Vanden Eynde
Jo Vandesompele
Ruben Van Paemel
Kimberly Verniers
Nurten Yigit
C3
Conference
2019
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes
Dries Rombaut
Bieke Decaesteker
Celine Everaert
Nurten Yigit
Katleen De Preter
Franki Speleman
Jo Vandesompele
Steve Lefever
Pieter Mestdagh
A1
Journal Article
in
SCIENTIFIC REPORTS
2019
LNCipedia 5 : towards a reference set of human long non-coding RNAs
Pieter-Jan Volders
Jasper Anckaert
Kenneth Verheggen
Justine Nuytens
Lennart Martens
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2019
Long noncoding RNA expression profiling in cancer : challenges and opportunities
Lucia Lorenzi
Francisco Avila Cobos
Anneleen Decock
Celine Everaert
Hetty Helsmoortel
Steve Lefever
Karen Verboom
Pieter-Jan Volders
Franki Speleman
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2019
Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA : a proof-of-principle study
Ruben Van Paemel
Andries De Koker
Charlotte Vandeputte
Tim Lammens
Genevieve Laureys
Jo Vandesompele
Nadine Van Roy
Nico Callewaert
Katleen De Preter
Bram De Wilde
Preprint
2019
Non-invasive classification of pediatric tumor types using reduced representation bisulfite sequencing of cell-free DNA : a proof-of-principle study
Ruben Van Paemel
Charlotte Vandeputte
Tim Lammens
Jo Vandesompele
Nadine Van Roy
Katleen De Preter
Bram De Wilde
C3
Conference
2019
PCR based target enrichment for variant confirmation, gene panels and multiplex PCR sample tracking in a whole exome sequencing workflow
Frauke Coppieters
Thalia Van Laethem
Matthias De Smet
Paul Coucke
Elfride De Baere
Kathleen Claes
Björn Menten
Jo Vandesompele
Steve Lefever
C3
Conference
2019
Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles
Celine Everaert
Hetty Helsmoortel
Anneleen Decock
Eva Hulstaert
Ruben Van Paemel
Kimberly Verniers
Justine Nuytens
Jasper Anckaert
Nele Nijs
Joeri Tulkens
Bert Dhondt
An Hendrix
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
SCIENTIFIC REPORTS
2019
Purification of high-quality RNA from a small number of fluorescence activated cell sorted zebrafish cells for RNA sequencing purposes
Siebe Loontiens
Lisa Depestel
Suzanne Vanhauwaert
Givani Dewyn
Charlotte Gistelinck
Karen Verboom
Wouter Van Loocke
Filip Matthijssens
Andy Willaert
Jo Vandesompele
Franki Speleman
Kaat Durinck
A1
Journal Article
in
BMC GENOMICS
2019
RNA-based liquid biopsies for better clinical management of Barrett’s esophagus and esophageal adenocarcinoma
Kathleen Schoofs
Annouck Philippron
Piet Pattyn
Jo Vandesompele
Katleen De Preter
C3
Conference
2019
RNAcentral : a hub of information for non-coding RNA sequences
Jo Vandesompele
Pieter-Jan Volders
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2019
SMARTer single cell total RNA sequencing
Karen Verboom
Celine Everaert
Nurten Yigit
Dries Rombaut
Jasper Anckaert
Franki Speleman
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2019
SMARTer single cell total RNA-sequencing
Karen Verboom
Celine Everaert
Nurten Yigit
Dries Rombaut
Jasper Anckaert
Franki Speleman
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2019
Searching for liquid RNA biomarkers for esophageal adenocarcinoma
Kathleen Schoofs
Annouck Philippron
Piet Pattyn
Jo Vandesompele
Katleen De Preter
C3
Conference
2019
The RNA Atlas, a single nucleotide resolution map of the human transcriptome
Lucia Lorenzi
Francisco Avila Cobos
Pieter-Jan Volders
Robrecht Cannoodt
Justine Nuytens
Jasper Anckaert
Steve Lefever
Tine Goovaerts
Tom Taghon
Karim Vermaelen
Ken Bracke
Tim De Meyer
Katleen De Preter
Jo Vandesompele
Pieter Mestdagh
Preprint
2019
The generation and use of recombinant extracellular vesicles as biological reference material
Edward Geeurickx
Joeri Tulkens
Bert Dhondt
Jan Van Deun
Lien Lippens
Glenn Vergauwen
Delphine De Sutter
Kris Gevaert
Francis Impens
Pieter-Jan Van Bockstal
Thomas De Beer
Geert Braems
Nico Callewaert
Pieter Mestdagh
Jo Vandesompele
Hannelore Denys
Sven Eyckerman
Olivier De Wever
An Hendrix
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
The human biofluid RNA atlas : expanding the liquid biopsy field beyond the blood stream
Eva Hulstaert
Kimberly Verniers
Justine Nuytens
Eveline Vanden Eynde
Nurten Yigit
Jasper Anckaert
Anja Geerts
Peggy Jacques
Guy Brusselle
Caroline Van Cauwenbergh
Kristien Roelens
Ellen Roets
Paul Ramaekers
Dimitri Hemelsoet
Pieter Hindryckx
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2019
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35
Celine Everaert
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
The proliferation of Duchenne muscular dystrophy fibroblasts cultured under inflammatory conditions is reduced by methylprednisolone through modulation of NFAT5 localization in the cell
dr. Sandrine Herbelet
Amanda Gonçalves
Jo Vandesompele
Jan De Bleecker
C3
Conference
2019
Therapeutic applications of SAMMSON lncRNA inhibition in uveal melanoma
Shanna Dewaele
Boel De Paepe
Louis Delhaye
Sven Eyckerman
Rudy Van Coster
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2019
Therapeutic applications of SAMMSON lncRNA inhibition in uveal melanoma
Shanna Dewaele
Katrien Vanderheyden
Boel De Paepe
Louis Delhaye
Sven Eyckerman
Rudy Van Coster
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2019
Therapeutic applications of SAMMSON lncRNA inhibition in uveal melanoma
Shanna Dewaele
Boel De Paepe
Louis Delhaye
Sven Eyckerman
Rudy Van Coster
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2019
2018
A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing
Karen Verboom
Wouter Van Loocke
Pieter-Jan Volders
Bieke Decaesteker
Francisco Avila Cobos
Tom Taghon
Pieter Van Vlierberghe
Jo Vandesompele
Franki Speleman
Kaat Durinck
A1
Journal Article
in
HAEMATOLOGICA
2018
A high-throughput 3’ UTR reporter screening identifies microRNA interactomes of cancer genes
Gert Van Peer
Evelien Mets
Shana Claeys
Steve Lefever
Maté Ongenaert
Pieter Rondou
Franki Speleman
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
PLOS ONE
2018
A mechanistic classification of clinical phenotypes in neuroblastoma
Franki Speleman
Jo Vandesompele
C3
Conference
2018
A mechanistic classification of clinical phenotypes in neuroblastoma
Franki Speleman
Jo Vandesompele
C3
Conference
2018
A mechanistic classification of clinical phenotypes in neuroblastoma.
Steve Lefever
Bram De Wilde
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
SCIENCE
2018
Assessing the biological signal of different RNA fractions for computational deconvolution of healthy tissues
Francisco Avila Cobos
Lucia Lorenzi
Jo Vandesompele
Katleen De Preter
Pieter Mestdagh
C3
Conference
2018
Assessment of risk refinement strategies for improved clinical outcome of neuroblastoma patients
Fjoralba Zeka
Jo Vandesompele
Pieter Mestdagh
Dissertation
2018
Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients
Fjoralba Zeka
Anneleen Decock
Alan Van Goethem
Katrien Vanderheyden
Tim Lammens
Hetty Helsmoortel
Genevieve Laureys
Tom Van Maerken
Franki Speleman
Katleen De Preter
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
JCI INSIGHT
2018
Circulating microRNA biomarkers for metastatic neuroblastoma
Fjoralba Zeka
Alan Van Goethem
Tim Lammens
Anneleen Decock
Hetty Helsmoortel
Genevieve Laureys
Franki Speleman
Tom Van Maerken
Katleen De Preter
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2018
Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background
Sabitri Ghimire
Margot Van der Jeught
Jitesh Neupane
Mina Popovic
Filip Van Nieuwerburgh
Pieter Mestdagh
Jo Vandesompele
Dieter Deforce
Björn Menten
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
SCIENTIFIC REPORTS
2018
Computational deconvolution of transcriptomics data from mixed cell populations
Francisco Avila Cobos
Jo Vandesompele
Pieter Mestdagh
Katleen De Preter
A1
Journal Article
in
BIOINFORMATICS
2018
Cross-cohort analysis identifies a TEAD4-MYCN positive-feedback loop as the core regulatory element of high-risk neuroblastoma
Katleen De Preter
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
CANCER DISCOVERY
2018
Data analysis methods for digital PCR quantification
Matthijs Vynck
Olivier Thas
Jo Vandesompele
Dissertation
2018
Detecting long non-coding RNA biomarkers in prostate cancer liquid biopsies : hype or hope?
Hetty Helsmoortel
Celine Everaert
Nicolaas Lumen
Piet Ost
Jo Vandesompele
A2
Journal Article
in
NON-CODING RNA RESEARCH
2018
Differential gene expression analysis of RNA-sequencing data : evaluation of DGE tools for long non-coding RNA-sequencing data
Alemu Takele Assefa
Jo Vandesompele
Olivier Thas
C3
Conference
2018
Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data
Alemu Takele Assefa
Celine Everaert
Pieter Mestdagh
Olivier Thas
Jo Vandesompele
A1
Journal Article
in
GENOME BIOLOGY
2018
Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice
Marjolijn Renard
Suzanne Vanhauwaert
Marine Vanhomwegen
Niels Vandamme
Steven Goossens
Geert Berx
Pieter Van Vlierberghe
Bieke Decaesteker
Jolien Van Laere
Irina Lambertz
Franki Speleman
Jo Vandesompele
Andy Willaert
A1
Journal Article
in
SCIENTIFIC REPORTS
2018
Fusion gene detection and variant calling in formalin-fixed paraffin-embedded tumor tissue using mRNA capture sequencing
Anneleen Decock
David Creytens
Joni Van der Meulen
Kimberly Verniers
Katrien Vanderheyden
Isabelle Rottiers
Jo Van Dorpe
Jo Vandesompele
C3
Conference
2018
In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors
Suzanne Vanhauwaert
Bieke Decaesteker
Sara De Brouwer
Carina Leonelli
Kaat Durinck
Pieter Mestdagh
Jo Vandesompele
Geertrui Denecker
Christophe Van Neste
Franki Speleman
Katleen De Preter
A1
Journal Article
in
SCIENTIFIC REPORTS
2018
Isolation of high-quality RNA from fluorescent activated cell sorted (FACS) zebrafish cells for RNA sequencing purposes
Siebe Loontiens
Suzanne Vanhauwaert
Lisa Depestel
Givani Dewyn
Charlotte Gistelinck
Karen Verboom
Filip Matthijssens
Andy Willaert
Jo Vandesompele
Franki Speleman
Kaat Durinck
C3
Conference
2018
Localization and expression of nuclear factor of activated T-cells 5 in myoblasts exposed to pro-inflammatory cytokines or hyperosmolar stress and in biopsies from myositis patients
dr. Sandrine Herbelet
Elly De Vlieghere
Amanda Gonçalves
Boel De Paepe
Gert Van Peer
Jo Vandesompele
Olivier De Wever
Jan De Bleecker
A1
Journal Article
in
FRONTIERS IN PHYSIOLOGY
2018
Longitudinal evaluation of murine serum microRNAs as biomarkers for neuroblastoma burden and therapeutic TP53 reactivation
Alan Van Goethem
Nurten Yigit
Celine Everaert
Fjoralba Zeka
Franki Speleman
Pieter Mestdagh
Jo Vandesompele
Tom Van Maerken
C3
Conference
2018
Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA
Ruben Van Paemel
Anneleen Decock
Charlotte Vandeputte
Tim Lammens
Genevieve Laureys
Franki Speleman
Wim Van Criekinge
Nadine Van Roy
Jo Vandesompele
Katleen De Preter
Bram De Wilde
C3
Conference
2018
Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA
Ruben Van Paemel
Anneleen Decock
Charlotte Vandeputte
Tim Lammens
Genevieve Laureys
Franki Speleman
Wim Van Criekinge
Nadine Van Roy
Jo Vandesompele
Katleen De Preter
Bram De Wilde
C3
Conference
2018
Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA
Ruben Van Paemel
Anneleen Decock
Charlotte Vandeputte
Tim Lammens
Genevieve Laureys
Franki Speleman
Wim Van Criekinge
Nadine Van Roy
Jo Vandesompele
Katleen De Preter
Bram De Wilde
C3
Conference
2018
On determining the power of digital PCR experiments
Matthijs Vynck
Jo Vandesompele
Olivier Thas
A1
Journal Article
in
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
2018
Pharmacological restoration of tumour suppressor protein p53 in neuroblastoma : seeking synergy and non-invasive biomarkers
Alan Van Goethem
Jo Vandesompele
Tom Van Maerken
A2
Journal Article
in
BELGIAN JOURNAL OF MEDICAL ONCOLOGY
2018
Prognostic and therapeutic implications of circulating androgen receptor gene copy number in prostate cancer patients using droplet digital polymerase chain reaction
Sarah Buelens
Tom Claeys
Bert Dhondt
Filip Poelaert
Matthijs Vynck
Nurten Yigit
Olivier Thas
Piet Ost
Jo Vandesompele
Nicolaas Lumen
Candy Kumps
A1
Journal Article
in
CLINICAL GENITOURINARY CANCER
2018
Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research
Edward Geeurickx
Jan Van Deun
Lien Lippens
Joeri Tulkens
Bert Dhondt
Glenn Vergauwen
Kris Gevaert
Francis Impens
Pieter-Jan Van Bockstal
Thomas De Beer
Sven Eyckerman
Pieter Mestdagh
Jo Vandesompele
Geert Braems
Hannelore Denys
Olivier De Wever
An Hendrix
C3
Conference
2018
Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research
Edward Geeurickx
Jan Van Deun
Lien Lippens
Joeri Tulkens
Bert Dhondt
Glenn Vergauwen
Kris Gevaert
Francis Impens
Pieter-Jan Van Bockstal
Thomas De Beer
Sven Eyckerman
Pieter Mestdagh
Jo Vandesompele
Geert Braems
Hannelore Denys
Marc Bracke
Olivier De Wever
An Hendrix
C3
Conference
2018
TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia
Karen Verboom
Wouter Van Loocke
Jo Vandesompele
Niels Vandamme
Geert Berx
Liesbet Martens
Yvan Saeys
Pieter Van Vlierberghe
Franki Speleman
Kaat Durinck
C3
Conference
2018
Targeted genomic screen reveals focal long non-coding RNA copy number alterations in cancer cell lines
Pieter-Jan Volders
Steve Lefever
Shalina Baute
Justine Nuytens
Katrien Vanderheyden
Björn Menten
Pieter Mestdagh
Jo Vandesompele
A2
Journal Article
in
NON-CODING RNA
2018
The TLX1 oncogene modules the enhancer RNA landscape in T-ALL
Karen Verboom
Wouter Van Loocke
Jo Vandesompele
Niels Vandamme
Geert Berx
Yvan Saeys
Liesbet Martens
Pieter Van Vlierberghe
Franki Speleman
Kaat Durinck
C3
Conference
2018
The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
ONCOGENE
2018
The extracellular RNA quality control (exRNAQC) study : controlling pre-analytical variables of RNA sequencing in blood-based precision medicine
Francisco Avila Cobos
Anneleen Decock
Katleen De Preter
Olivier De Wever
Bram De Wilde
Bert Dhondt
Celine Everaert
Hetty Helsmoortel
An Hendrix
Eva Hulstaert
Pieter Mestdagh
Nele Nijs
Annouck Philippron
Jo Vandesompele
Ruben Van Paemel
Kimberly Verniers
Nurten Yigit
C3
Conference
2018
The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease
Bram De Wilde
Anneleen Beckers
Katleen De Preter
Pauline Depuydt
Pieter Mestdagh
Tom Sante
Steve Lefever
Elien Vandermarliere
Lennart Martens
Björn Menten
Jo Vandesompele
Franki Speleman
A2
Journal Article
in
ONCOTARGET
2018
The neuroblastoma-specific lncRNA NESPR activates PHOX2B expression and is essential for neuroblastoma cell survival
Dries Rombaut
Louis Delhaye
Eva D'haene
Nurten Yigit
Celine Everaert
Björn Menten
Jo Vandesompele
Sven Eyckerman
Steve Lefever
Pieter Mestdagh
C3
Conference
2018
The ornithine decarboxylase G316A promoter polymorphism impacts neuroblastoma clinical outcome and may identify patients particularly susceptible to polyamine inhibition
Tom Van Maerken
Jo Vandesompele
C3
Conference
2018
The potential of methylome sequencing in the diagnostic work : up of pediatric solid tumors
Ruben Van Paemel
Charlotte Vandeputte
Bram De Wilde
Katleen De Preter
Nadine Van Roy
Jo Vandesompele
Tim Lammens
Wim Van Criekinge
Nico Callewaert
Anneleen Decock
C3
Conference
2018
Therapeutic applications of SAMMSON lncRNA inhibition in uveal melanoma
Shanna Dewaele
Katrien Vanderheyden
Boel De Paepe
Rudy Van Coster
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2018
Therapeutic applications of SAMMSON lncRNA inhibition in uveal melanoma
Shanna Dewaele
Boel De Paepe
Rudy Van Coster
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2018
Zipper plot : visualizing transcriptional activity of genomic regions
Francisco Avila Cobos
Pieter-Jan Volders
Celine Everaert
Dries Rombaut
Jo Vandesompele
Katleen De Preter
Pieter Mestdagh
C3
Conference
2018
2017
A unified censored normal regression model for qPCR differential gene expression analysis
Peter Pipelers
Lieven Clement
Matthijs Vynck
Jan Hellemans
Jo Vandesompele
Olivier Thas
A1
Journal Article
in
PLOS ONE
2017
Androgen receptor gene copy number detection using droplet digital PCR and its therapeutic consequences in prostate cancer patients
Sarah Buelens
Tom Claeys
Candy Kumps
Bert Dhondt
Filip Poelaert
Nurten Yigit
Matthijs Vynck
Olivier Thas
Piet Ost
Jo Vandesompele
Nicolaas Lumen
C3
Conference
2017
Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay (vol 6, 36111, 2016)
Wim Trypsteen
Clarissa Van Hecke
Pieter Mestdagh
Steve Lefever
Yvan Saeys
Pieter De Bleser
Jo Vandesompele
Linos Vandekerckhove
Ward De Spiegelaere
Correction
2017
Direct comparison of distinct naive pluripotent states in human embryonic stem cells
Sharat Warrier
Margot Van der Jeught
Galbha Duggal
Laurentijn Tilleman
Jasin Taelman
Mina Popovic
Sylvie Lierman
Susana Marina Chuva de Sousa Lopes
Ann Van Soom
Luc Peelman
Filip Van Nieuwerburgh
Dieter De Coninck
Björn Menten
Pieter Mestdagh
Jo Vandesompele
Dieter Deforce
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
NATURE COMMUNICATIONS
2017
Direct detection of circulating microRNAs unveiled the absence of microRNA-218-5p in smoker subjects : reply
Griet Conickx
Pieter Mestdagh
Jo Vandesompele
Guy Brusselle
Ken Bracke
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2017
Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma
Alan Van Goethem
Nurten Yigit
Franki Speleman
Jo Vandesompele
Tom Van Maerken
A1
Journal Article
in
ONCOTARGET
2017
EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research
Jan Van Deun
Pieter Mestdagh
Els Beghein
Laurence Bertier
Geert Berx
Clara Casert
Bert Dhondt
Edward Geeurickx
Jan Gettemans
Farzaneh Ghazavi
Hetty Helsmoortel
Carina Leonelli
Lien Lippens
Gloria Milani
Liselot Mus
Quentin Rousseau
Bieke Soen
Anneleen Steels
Joeri Tulkens
Isabel Van Audenhove
Alan Van Goethem
Nadine Van Roy
Niels Vandamme
Suzanne Vanhauwaert
Glenn Vergauwen
Annelynn Wallaert
Olivier De Wever
Jo Vandesompele
An Hendrix
A1
Journal Article
in
NATURE METHODS
2017
Evaluation of relative quantification of alternatively spliced transcripts using droplet digital PCR
Mattias Van Heetvelde
Wouter Van Loocke
Wim Trypsteen
Annelot Baert
Katrien Vanderheyden
Brecht Crombez
Jo Vandesompele
Kim De Leeneer
Kathleen Claes
A2
Journal Article
in
BIOMOLECULAR DETECTION AND QUANTIFICATION
2017
High-throughput PCR assay design for targeted resequencing using primerXL
Steve Lefever
Filip Pattyn
Bram De Wilde
Frauke Coppieters
Sarah De Keulenaer
Jan Hellemans
Jo Vandesompele
A1
Journal Article
in
BMC BIOINFORMATICS
2017
Influence of microRNAs and long non-coding RNAs in cancer chemoresistance
Jo Vandesompele
A1
Journal Article
in
GENES
2017
Long non-coding RNAs in cutaneous melanoma : clinical perspectives
Eva Hulstaert
Lieve Brochez
Pieter-Jan Volders
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
ONCOTARGET
2017
MicroRNA expression analysis using small RNA sequencing discovery and RT-qPCR-based validation
Alan Van Goethem
Pieter Mestdagh
Tom Van Maerken
Jo Vandesompele
Bookchapter
in
Functional genomics : methods and protocols
2017
MicroRNA profiling reveals a role for microRNA-218-5p in the pathogenesis of chronic obstructive pulmonary disease
Griet Conickx
Pieter Mestdagh
Francisco Avila Cobos
Fien Verhamme
Tania Maes
Leen Seys
Lies Lahousse
Guy Joos
Jo Vandesompele
Ken Bracke
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2017
MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
DIABETOLOGIA
2017
Model-based classification for digital PCR : your Umbrella for rain
Bart Jacobs
Els Goetghebeur
Jo Vandesompele
Ariane De Ganck
Lieven Clement
A1
Journal Article
in
ANALYTICAL CHEMISTRY
2017
Noncoding after all : biases in proteomics data do not explain observed absence of lncRNA translation products
Kenneth Verheggen
Pieter-Jan Volders
Pieter Mestdagh
Gerben Menschaert
Petra Van Damme
Kris Gevaert
Lennart Martens
Jo Vandesompele
A1
Journal Article
in
JOURNAL OF PROTEOME RESEARCH
2017
Nonparametric simulation to evaluate the performance of statistical methods for differential gene expression analysis of long non-coding RNA-seq data in cancer studies
Alemu Takele Assefa
Olivier Thas
Jo Vandesompele
C3
Conference
2017
PAN-cancer identification of ncRNAs with a high therapeutic and diagnostic potential
Celine Everaert
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2017
Pancreatic cancer : hope to improve prognosis through thorough analysis of DNA and RNA biomarkers for detection and therapy monitoring in liquid biopsies
Greet Wieme
Frederik Berrevoet
Aude Vanlander
Marc De Man
Karen Geboes
Jo Van Dorpe
Anne Hoorens
Malaïka Van der Linden
Celine Everaert
Anneleen Decock
Jo Vandesompele
Björn Menten
Kathleen Claes
C3
Conference
2017
Quality control of digital PCR assays and platforms
Matthijs Vynck
Jo Vandesompele
Olivier Thas
A1
Journal Article
in
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
2017
Restoration of p53 in neuroblastoma : seeking synergy and non-invasive biomakers
Alan Van Goethem
Tom Van Maerken
Jo Vandesompele
Dissertation
2017
Second hit landscape in BRCA-associated breast cancer
Mattias Van Heetvelde
Mieke Van Bockstal
Trees Lepez
Steve Lefever
Leen Pieters
Kathleen Lambein
Marleen Praet
Frauke Coppieters
Nadine Van Roy
Jo Vandesompele
Dieter Deforce
Anne Vral
Bruce Poppe
Kim De Leeneer
Jo Van Dorpe
Kathleen Claes
C3
Conference
2017
Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth
Lore Lapeire
An Hendrix
Mieke Van Bockstal
Jo Vandesompele
Geert Braems
Rudy Van den Broecke
Marc Bracke
Veronique Cocquyt
Hannelore Denys
Olivier De Wever
A1
Journal Article
in
ONCOTARGET
2017
Stage 4S neuroblastoma tumors show a characteristic DNA methylation portrait
Anneleen Decock
Maté Ongenaert
Bram De Wilde
Franki Speleman
Jo Vandesompele
C3
Conference
2017
The extracellular RNA quality control (exRNAQC) study : testing and controlling pre-analytical variables of RNA sequencing on liquid biopsies
Anneleen Decock
Olivier De Wever
Bert Dhondt
Thibaut D'huyvetter
Hetty Helsmoortel
An Hendrix
Annouck Philippron
Kimberly Verniers
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2017
The occurrence and therapeutic consequences of androgen receptor copy number gain in prostate cancer patients using Droplet Digital PCR
Sarah Buelens
Tom Claeys
Candy Kumps
Bert Dhondt
Filip Poelaert
Matthijs Vynck
Olivier Thas
Piet Ost
Jo Vandesompele
Nicolaas Lumen
C3
Conference
2017
The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome
Lotte Pyfferoen
Elisabeth Brabants
Celine Everaert
Nancy De Cabooter
Kelly Heyns
Kim Deswarte
Manon Vanheerswynghels
Sofie De Prijck
Melissa Dullaers
Hamida Hammad
Olivier De Wever
Pieter Mestdagh
Jo Vandesompele
Bart Lambrecht
Karim Vermaelen
A1
Journal Article
in
ONCOIMMUNOLOGY
2017
Therapeutic applications of SAMMSON lncRNA inhibition in uveal melanoma
Shanna Dewaele
Katrien Vanderheyden
Boel De Paepe
Rudy Van Coster
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2017
Therapeutic applications of SAMMSON lncRNA inhibition in uveal melanoma
Shanna Dewaele
Katrien Vanderheyden
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2017
Thermodynamic framework to assess low abundance DNA mutation detection by hybridization
Nadine Van Roy
Jo Vandesompele
A1
Journal Article
in
PLOS ONE
2017
Zipper plot : visualizing transcriptional activity of genomic regions
Francisco Avila Cobos
Pieter-Jan Volders
Celine Everaert
Dries Rombaut
Jo Vandesompele
Katleen De Preter
Pieter Mestdagh
A1
Journal Article
in
BMC BIOINFORMATICS
2017
decodeRNA-predicting non-coding RNA functions using guilt-by-association
Steve Lefever
Pieter-Jan Volders
Manuel Luypaert
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
2017
lncRNA discovery in the HIV replication cycle adds new layer in HIV-host interplay
Wim Trypsteen
Clarissa Van Hecke
Pieter Mestdagh
Steve Lefever
Pieter De Bleser
Jo Vandesompele
Ward De Spiegelaere
Linos Vandekerckhove
C3
Conference
2017
mRNA capture sequencing enabled liquid biopsy screening
Jo Vandesompele
C3
Conference
2017
mRNA capture sequencing enabled liquid biopsy screening
Anneleen Decock
Olivier De Wever
Bert Dhondt
An Hendrix
Hetty Helsmoortel
Pieter Mestdagh
Piet Ost
Jo Vandesompele
Glenn Vergauwen
C3
Conference
2017
miSTAR : miRNA target prediction through modeling quantitative and qualitative miRNA binding site information in a stacked model structure
Gert Van Peer
Michiel Stock
Pieter-Jan Volders
Jo Vandesompele
Bernard De Baets
Willem Waegeman
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2017
2016
An embryonic stem cell activated FOXM1 transcriptional program marks ultra-high-risk primary neuroblastoma patients for FDI-6 small molecule inhibition
Suzanne Vanhauwaert
Carina Leonelli
Sara De Brouwer
Jolien De Wyn
Anneleen Beckers
Jo Vandesompele
Franki Speleman
Katleen De Preter
C3
Conference
2016
Asthma inflammatory phenotypes show differential microRNA expression in sputum
Tania Maes
Francisco Avila Cobos
Katleen De Preter
Ken Bracke
Griet Conickx
Jo Vandesompele
Lies Lahousse
Pieter Mestdagh
Guy Joos
Guy Brusselle
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2016
Benchmarking of RNA-sequencing analysis workflows using whole-transcriptome RT-qPCR expression data
Celine Everaert
Ariane De Ganck
Jan Hellemans
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2016
DNA methylation profiling of primary neuroblastoma tumors using methyl-CpG-binding domain sequencing
Anneleen Decock
Maté Ongenaert
Wim Van Criekinge
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
SCIENTIFIC DATA
2016
Decoding cancer transcriptomes using public RNA sequencing data
Celine Everaert
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2016
Decoding cancer transcriptomes using public RNA sequencing data
Celine Everaert
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2016
Decoding cancer transcriptomes using public RNA sequencing data
Celine Everaert
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2016
Depletion of tRNA-halves enables effective small RNA sequencing of low-input murine serum samples
Alan Van Goethem
Nurten Yigit
Celine Everaert
Liselot Mus
Franki Speleman
Pieter Mestdagh
Tom Van Maerken
Jo Vandesompele
A1
Journal Article
in
SCIENTIFIC REPORTS
2016
Differential expression of lncRNAs during the HIV replication cycle : an underestimated layer in the HIV-host interplay
Wim Trypsteen
Clarissa Van Hecke
Pieter Mestdagh
Steve Lefever
Yvan Saeys
Pieter De Bleser
Jo Vandesompele
Linos Vandekerckhove
Ward De Spiegelaere
A1
Journal Article
in
SCIENTIFIC REPORTS
2016
Dissecting the NOTCH1 driven transcriptional landscape in T-cell acute lymphoblastic leukemia at single cell level
Karen Verboom
Kaat Durinck
Celine Everaert
Robrecht Cannoodt
Pieter Van Vlierberghe
Jo Vandesompele
Franki Speleman
C3
Conference
2016
EV-TRAQ: tracking transparent reporting and quality to boost standardized extracellular vesicle research
Jan Van Deun
Pieter Mestdagh
Jo Vandesompele
Olivier De Wever
An Hendrix
C3
Conference
2016
Endogenous controls for miRNA analysis in renal cells and tissue
Jo Vandesompele
C3
Conference
2016
Eradication of neuroblastoma by suppressing the expression of a single long noncoding RNA
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2016
Expanding the TLX1 regulome in T-cell acute lymphoblastic leukemia towards long noncoding RNAs
Kaat Durinck
Wouter Van Loocke
Inge Van de Walle
Joni Van der Meulen
Pieter-Jan Volders
Nadine Van Roy
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
Pieter Rondou
Tom Taghon
Pieter Van Vlierberghe
Franki Speleman
C3
Conference
2016
Exploring the neuroblastoma DNA methylome: from biology to biomarker
Anneleen Decock
Jo Vandesompele
Franki Speleman
Maté Ongenaert
Dissertation
2016
Flexible analysis of digital PCR experiments using generalized linear mixed models
Matthijs Vynck
Jo Vandesompele
Björn Menten
Olivier Thas
A2
Journal Article
in
BIOMOLECULAR DETECTION AND QUANTIFICATION
2016
Identification of non-invasive biomarkers for treatment response in neuroblastoma by circulating miRNA profiling
Alan Van Goethem
Nurten Yigit
Celine Everaert
Pieter Mestdagh
Franki Speleman
Tom Van Maerken
Jo Vandesompele
C3
Conference
2016
LncRNAs in the context of Chronic Obstructive Pulmonary Disease (COPD) are associated to immune response and metabolism of xenobiotics
Francisco Avila Cobos
Ken Bracke
Jo Vandesompele
Kimberly Verniers
Guy Joos
Katleen De Preter
Guy Brusselle
Pieter Mestdagh
C3
Conference
2016
Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR
Pieter Mestdagh
Steve Lefever
Pieter-Jan Volders
Stefaan Derveaux
Jo Vandesompele
A1
Journal Article
in
SCIENTIFIC DATA
2016
Long non-coding RNAs as novel components in the TP53 pathway
Dries Rombaut
Steve Lefever
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2016
Long non-coding RNAs as novel components in the TP53 pathway
Dries Rombaut
Steve Lefever
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2016
Long noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Inge Van de Walle
Filip Matthijssens
Pieter-Jan Volders
Francisco Avila Cobos
Dries Rombaut
Pieter Rondou
Pieter Mestdagh
Jo Vandesompele
Bruce Poppe
Tom Taghon
Pieter Van Vlierberghe
Franki Speleman
A1
Journal Article
in
LEUKEMIA
2016
Mapping the methodological diversity of EV isolation and characterization
Jan Van Deun
Pieter Mestdagh
Jo Vandesompele
Olivier De Wever
An Hendrix
C3
Conference
2016
Melanoma addiction to the long non-coding RNA SAMMSON
Sven Eyckerman
Carina Leonelli
Katrien Vanderheyden
Stefan Van Aelst
Kris Gevaert
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
NATURE
2016
Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma
Anneleen Decock
Maté Ongenaert
Robrecht Cannoodt
Kimberly Verniers
Bram De Wilde
Genevieve Laureys
Nadine Van Roy
Katleen De Preter
Franki Speleman
Jo Vandesompele
C3
Conference
2016
Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma
Anneleen Decock
Maté Ongenaert
Robrecht Cannoodt
Kimberly Verniers
Bram De Wilde
Genevieve Laureys
Nadine Van Roy
Katleen De Preter
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
ONCOTARGET
2016
Microrna-218-5p is implicated in the pathogenesis of chronic obstructive pulmonary disease
Griet Conickx
Pieter Mestdagh
Francisco Avila Cobos
Fien Verhamme
Tania Maes
Lies Lahousse
Guy Joos
Jo Vandesompele
Ken Bracke
Guy Brusselle
C3
Conference
2016
NFAT5 in Duchenne muscular dystrophy cultured myoblasts after exposure to hyperosmolar salt conditions
dr. Sandrine Herbelet
Amanda Gonçalves
Elly De Vlieghere
Gert Van Peer
Boel De Paepe
Chris Guerin
Jo Vandesompele
Olivier De Wever
Jan De Bleecker
C3
Conference
2016
PAN-cancer identification of ncRNAs with a high therapeutic and diagnostic potential
Celine Everaert
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2016
PAN-cancer identification of ncRNAs with a high therapeutic and diagnostic potential
Celine Everaert
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2016
PAN-cancer therapeutic target identification by omics data integration
Celine Everaert
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2016
Quantitative and functional requirements for bioluminescent cancer models
Lynn Feys
Benedicte Descamps
Christian Vanhove
Jo Vandesompele
Katrien Vanderheyden
Kathy Messens
Marc Bracke
Olivier De Wever
A1
Journal Article
in
IN VIVO
2016
RT-qPCR gene expression analysis in zebrafish : preanalytical precautions and use of expressed repetitive elements for normalization
Suzanne Vanhauwaert
Steve Lefever
Paul Coucke
Franki Speleman
Anne De Paepe
Jo Vandesompele
Andy Willaert
A1
Journal Article
in
Methods in Cell Biology
2016
Rol van microRNA in neutrofiel astma
Tania Maes
Francisco Avila Cobos
Katleen De Preter
Ken Bracke
Griet Conickx
Jo Vandesompele
Lies Lahousse
Pieter Mestdagh
Guy Joos
Guy Brusselle
A4
Journal Article
in
BLOEDVATEN HART LONGEN
2016
Selective cross-cohort discovery of transcriptional mechanisms presiding over high-risk neuroblastoma subtype state maintenance
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2016
Stage 4S neuroblastoma tumors show a characteristic DNA methylation portrait
Anneleen Decock
Maté Ongenaert
Bram De Wilde
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
EPIGENETICS
2016
Straightforward and sensitive RT-qPCR based gene expression analysis of FFPE samples
Fjoralba Zeka
Katrien Vanderheyden
Els De Smet
Claude Cuvelier
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
SCIENTIFIC REPORTS
2016
Targeted resequencing and variant validation using pxlence PCR assays
Frauke Coppieters
Kimberly Verniers
Kim De Leeneer
Jo Vandesompele
Steve Lefever
A2
Journal Article
in
BIOMOLECULAR DETECTION AND QUANTIFICATION
2016
The T-ALL oncogene TLX1 controls enhancer lncRNA expression
Karen Verboom
Kaat Durinck
Wouter Van Loocke
Filip Matthijssens
Inge Van de Walle
Annelynn Wallaert
Pieter-Jan Volders
Nadine Van Roy
Yves Benoit
Bruce Poppe
Pieter Rondou
Pieter Mestdagh
Jo Vandesompele
Tom Taghon
Pieter Van Vlierberghe
Franki Speleman
C3
Conference
2016
The core protein to myogenesis NFAT5 forms aggresomes in normal and Duchenne muscular dystrophy myotubes exposed to cell stressors
dr. Sandrine Herbelet
Elly De Vlieghere
Gert Van Peer
Boel De Paepe
Jo Vandesompele
Olivier De Wever
Jan De Bleecker
C3
Conference
2016
Thorough second hit analysis in BRCA1/2 associated breast cancer
Mattias Van Heetvelde
Trees Lepez
Leen Pieters
Steve Lefever
Jo Van Dorpe
Marleen Praet
Frauke Coppieters
Jo Vandesompele
Nadine Van Roy
Dieter Deforce
Anne Vral
Kim De Leeneer
Kathleen Claes
C3
Conference
2016
Thorough second-hit analysis in BRCA1/2-associated breast cancer
Mattias Van Heetvelde
Trees Lepez
Leen Pieters
Steve Lefever
Jo Van Dorpe
Marleen Praet
Frauke Coppieters
Jo Vandesompele
Nadine Van Roy
Dieter Deforce
Anne Vral
Kim De Leeneer
Kathleen Claes
C3
Conference
2016
2015
Alternative routes to induce naive pluripotency in human embryonic stem cells
Galbha Duggal
Sharat Warrier
Sabitri Ghimire
Margot Van der Jeught
Sylvie Lierman
Tom Deroo
Luc Peelman
Ann Van Soom
Maria Cornelissen
Björn Menten
Pieter Mestdagh
Jo Vandesompele
Dieter Deforce
Petra De Sutter
Susana Marina Chuva de Sousa Lopes
Björn Heindryckx
A1
Journal Article
in
STEM CELLS
2015
An embryonic stem cell activated FOXM1 transcriptional program marks ultra-high-risk primary neuroblastoma patients for FDI-6 small molecule inhibition
Suzanne Vanhauwaert
Carina Leonelli
Sara De Brouwer
Jolien De Wyn
Anneleen Beckers
Jo Vandesompele
Franki Speleman
Katleen De Preter
C3
Conference
2015
An update on LNCipedia : a database for annotated human lncRNA sequences
Pieter-Jan Volders
Kenneth Verheggen
Gerben Menschaert
Klaas Vandepoele
Lennart Martens
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2015
Best-in-class PCR based target enrichment for NGS panels and Sanger variant confirmation
Steve Lefever
Frauke Coppieters
Jo Vandesompele
C3
Conference
2015
Comparison of RNA-seq and microarray-based models for clinical endpoint prediction
Jo Vandesompele
A1
Journal Article
in
GENOME BIOLOGY
2015
Data analysis of droplet digital PCR with generalized linear mixed models
Olivier Thas
Matthijs Vynck
Jo Vandesompele
C3
Conference
2015
Exploring lncRNAs in cancer : tools for discovery and characterization of cancer associated lncRNAs
Pieter-Jan Volders
Jo Vandesompele
Kris Gevaert
Dissertation
2015
Flexible, scalable, and efficient targeted resequencing on a benchtop sequencer for variant detection in clinical practice
Kim De Leeneer
Jan Hellemans
Wouter Steyaert
Steve Lefever
Inge Vereecke
Eveline Debals
Brecht Crombez
Machteld Baetens
Mattias Van Heetvelde
Frauke Coppieters
Jo Vandesompele
Annelies De Jaegher
Elfride De Baere
Paul Coucke
Kathleen Claes
A1
Journal Article
in
HUMAN MUTATION
2015
GLMMs for nucleic acid concentration estimation in digital droplet PCR
Matthijs Vynck
Jo Vandesompele
Olivier Thas
C3
Conference
2015
Genome wide expression profiling of p53 regulated miRNAs in neuroblastoma
Ali Rihani
Alan Van Goethem
Maté Ongenaert
Sara De Brouwer
Pieter-Jan Volders
Katleen De Preter
Pieter Mestdagh
Franki Speleman
Jo Vandesompele
Tom Van Maerken
A1
Journal Article
in
SCIENTIFIC REPORTS
2015
Identification of miRNAs contributing to neuroblastoma chemoresistance
Duncan Ayers
Pieter Mestdagh
Tom Van Maerken
Jo Vandesompele
A1
Journal Article
in
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
2015
Improving accuracy and precision of dPCR experiments by relying on multiple reference genes
Matthijs Vynck
Jo Vandesompele
Olivier Thas
C3
Conference
2015
Individual patient risk stratification of high-risk neuroblastomas using a two-gene score suited for clinical use
Katleen De Preter
Jo Vandesompele
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2015
Inhibition of CDK4/6 as a novel therapeutic option for neuroblastoma
Ali Rihani
Jo Vandesompele
Franki Speleman
Tom Van Maerken
A1
Journal Article
in
CANCER CELL INTERNATIONAL
2015
Integrated and cross-species omics analyses identify the DNA damage response pathway as an important vulnerable pathway in aggressive neuroblastoma tumors
Katleen De Preter
Anneleen Beckers
Suzanne Vanhauwaert
Annelies Fieuw
Sara De Brouwer
Pieter Mestdagh
Jo Vandesompele
Franki Speleman
C3
Conference
2015
Long non-coding RNAs as upstream regulators and downstream effectors of TP53 activity in neuroblastoma
Dries Rombaut
Steve Lefever
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2015
MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma
Anneleen Beckers
Gert Van Peer
Hetty Helsmoortel
Yves Benoit
Jo Vandesompele
Katleen De Preter
Franki Speleman
A1
Journal Article
in
CANCER LETTERS
2015
MYCN-targeting miRNAs are predominantly downregulated during MYCN-driven neuroblastoma tumor formation
Anneleen Beckers
Gert Van Peer
Pieter Mestdagh
Jo Vandesompele
Katleen De Preter
Franki Speleman
A1
Journal Article
in
ONCOTARGET
2015
Massively parallel sequencing technologies in neuroblastoma research
Bram De Wilde
Jo Vandesompele
Franki Speleman
Dissertation
2015
Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma
Anneleen Decock
Maté Ongenaert
Robrecht Cannoodt
Kimberly Verniers
Bram De Wilde
Genevieve Laureys
Nadine Van Roy
Katleen De Preter
Franki Speleman
Jo Vandesompele
C3
Conference
2015
MiR-34a deficiency accelerates medulloblastoma formation in vivo
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2015
MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia
Evelien Mets
Joni Van der Meulen
Gert Van Peer
Pieter Mestdagh
Inge Van de Walle
Tim Lammens
Steven Goossens
Barbara De Moerloose
Yves Benoit
Nadine Van Roy
Bruce Poppe
Jo Vandesompele
Tom Taghon
Pieter Rondou
Pieter Van Vlierberghe
Franki Speleman
A1
Journal Article
in
LEUKEMIA
2015
Non-coding RNAs and respiratory disease
Pieter Mestdagh
Jo Vandesompele
Guy Brusselle
Karim Vermaelen
A1
Journal Article
in
THORAX
2015
Non-coding RNAs in the pathogenesis of COPD
Elise De Smet
Pieter Mestdagh
Jo Vandesompele
Guy Brusselle
Ken Bracke
A1
Journal Article
in
THORAX
2015
Oncogenic dysregulations in neuroblastoma are associated with distal large chromosomal aberrations
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2015
RDML-Ninja and RDMLdb for standardized exchange of qPCR data
Steve Lefever
Jo Vandesompele
A1
Journal Article
in
BMC BIOINFORMATICS
2015
RNA expression signatures and posttranscriptional regulation in diabetic nephropathy
Anneleen Beckers
Jo Vandesompele
A1
Journal Article
in
NEPHROLOGY DIALYSIS TRANSPLANTATION
2015
RT-qPCR-based quantification of small non-coding RNAs
Fjoralba Zeka
Pieter Mestdagh
Jo Vandesompele
Bookchapter
in
Small non-coding RNAs : methods and protocols
2015
Renal microRNA- and RNA-profiles in progressive chronic kidney disease
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
2015
Revised risk estimation and treatment stratification of low- and intermediate-risk neuroblastoma patients by integrating clinical and molecular prognostic markers
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2015
lncRNAs as upstream regulators and downstream effectors of TP53 in neuroblastoma
Dries Rombaut
Steve Lefever
Pieter-Jan Volders
Alan Van Goethem
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2015
miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin
Pieter Mestdagh
Anneleen Beckers
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2015
miRNome-wide high-throughput microRNA target identification
Gert Van Peer
Jo Vandesompele
Pieter Mestdagh
Dissertation
2015
2014
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium
Jo Vandesompele
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2014
CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients
Ali Rihani
Bram De Wilde
Genevieve Laureys
Franki Speleman
Jo Vandesompele
Tom Van Maerken
A1
Journal Article
in
PLOS ONE
2014
CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients
Ali Rihani
Bram De Wilde
Fjoralba Zeka
Genevieve Laureys
Franki Speleman
Jo Vandesompele
Tom Van Maerken
C3
Conference
2014
CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients
Ali Rihani
Bram De Wilde
Fjoralba Zeka
Genevieve Laureys
Franki Speleman
Jo Vandesompele
Tom Van Maerken
C3
Conference
2014
Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and JAK3/STAT3 signaling
Lore Lapeire
An Hendrix
Kathleen Lambein
Mieke Van Bockstal
Geert Braems
Rudy Van den Broecke
Pieter Mestdagh
Jo Vandesompele
Christian Vanhove
Veronique Cocquyt
Marc Bracke
Hannelore Denys
Olivier De Wever
C3
Conference
2014
Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and Jak/STAT3 signaling
Lore Lapeire
An Hendrix
Kathleen Lambein
Mieke Van Bockstal
Geert Braems
Rudy Van den Broecke
Pieter Mestdagh
Jo Vandesompele
Christian Vanhove
Marc Bracke
Veronique Cocquyt
Hannelore Denys
Olivier De Wever
A1
Journal Article
in
CANCER RESEARCH
2014
Characterization of the p53 network and new therapeutic opportunities in neuroblastoma
Ali Rihani
Jo Vandesompele
Tom Van Maerken
Dissertation
2014
Early targets of miR-34a in neuroblastoma
Jonathan Vandenbussche
Pieter Mestdagh
Jo Vandesompele
Kris Gevaert
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2014
Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells
Ajay Palagani
Karen Heyninck
Sarah Gerlo
Pieter Mestdagh
Jo Vandesompele
Wim Vanden Berghe
A1
Journal Article
in
PLOS ONE
2014
Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
NATURE METHODS
2014
Evaluation of targeted drugs in combination with the MDM2 antagonist RG7388 in neuroblastoma
Alan Van Goethem
Franki Speleman
Jo Vandesompele
Tom Van Maerken
C3
Conference
2014
Evaluation of targeted drugs in combination with the MDM2 antagonist RG7388 in neuroblastoma
Alan Van Goethem
Franki Speleman
Jo Vandesompele
Tom Van Maerken
C3
Conference
2014
Evaluation of targeted drugs in combination with the MDM2 antagonist RG7388 in neuroblastoma
Alan Van Goethem
Franki Speleman
Jo Vandesompele
Tom Van Maerken
C3
Conference
2014
Evaluation of targeted drugs in combination with the MDM2 antagonist RG7388 in neuroblastoma
Alan Van Goethem
Franki Speleman
Jo Vandesompele
Tom Van Maerken
C3
Conference
2014
Expressed repeat elements improve RT-qPCR normalization across a wide range of zebrafish gene expression studies
Suzanne Vanhauwaert
Gert Van Peer
Ali Rihani
Pieter Rondou
Steve Lefever
Anne De Paepe
Paul Coucke
Franki Speleman
Jo Vandesompele
Andy Willaert
A1
Journal Article
in
PLOS ONE
2014
Genetisch geïnspireerde toekomstperspectieven voor de therapie van het neuroblastoom
Bram De Wilde
Tom Van Maerken
Katleen De Preter
Nadine Van Roy
Genevieve Laureys
Jo Vandesompele
Franki Speleman
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2014
Genome-wide methylation analysis unravels differential DNA methylation patterns between (prognostic) neuroblastoma patient subgroups
Anneleen Decock
Maté Ongenaert
Katleen De Preter
Franki Speleman
Jo Vandesompele
C3
Conference
2014
Illumina sequencing of 15 deafness genes using fragmented amplicons
Filip Van Nieuwerburgh
Sarah De Keulenaer
Joachim De Schrijver
Jo Vandesompele
Wim Van Criekinge
Paul Coucke
Dieter Deforce
A2
Journal Article
in
BMC RESEARCH NOTES
2014
Integrative analysis of the NOTCH1 regulatory network identifies key downstream lncRNAs in acute T-cell lymphoblastic leukemia and normal T-cell development
Annelynn Wallaert
Kaat Durinck
Pieter Rondou
Inge Van de Walle
Wouter Van Loocke
Pieter-Jan Volders
Maté Ongenaert
Nadine Van Roy
Bruce Poppe
Yves Benoit
Jo Vandesompele
Tom Taghon
Pieter Van Vlierberghe
Franki Speleman
C3
Conference
2014
Lack of association between MDM2 promoter SNP309 and clinical outcome in patients with neuroblastoma
Ali Rihani
Tom Van Maerken
Bram De Wilde
Fjoralba Zeka
Genevieve Laureys
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
PEDIATRIC BLOOD & CANCER
2014
LncRNA profiling in T-cell acute lymphoblastic leukemia predicts a functional connection between lncRNAs and the major T-ALL genetic subgroups
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Pieter-Jan Volders
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
Pieter Van Vlierberghe
Pieter Rondou
Franki Speleman
C3
Conference
2014
Lung tumours reprogram pulmonary dendritic cell immunogenicity at the microRNA level
Lotte Pyfferoen
Pieter Mestdagh
Karl Vergote
Nancy De Cabooter
Jo Vandesompele
Bart Lambrecht
Karim Vermaelen
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2014
MYCN safeguards its upregulated expression through negatively controlling its upstream miRNAs
Anneleen Beckers
Gert Van Peer
Jo Vandesompele
Katleen De Preter
Franki Speleman
C3
Conference
2014
MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia
Evelien Mets
Gert Van Peer
Joni Van der Meulen
Tom Taghon
Steven Goossens
Pieter Mestdagh
Yves Benoit
Barbara De Moerloose
Nadine Van Roy
Bruce Poppe
Jo Vandesompele
Pieter Van Vlierberghe
Franki Speleman
Pieter Rondou
A1
Journal Article
in
HAEMATOLOGICA
2014
Pharmacologic activation of wild-type p53 by nutlin therapy in childhood cancer
Tom Van Maerken
Ali Rihani
Alan Van Goethem
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
CANCER LETTERS
2014
Promoter DNA-methylation in the TH-MYCN neuroblastoma mouse model
Anneleen Beckers
Wouter Van Loocke
Anneleen Decock
Maté Ongenaert
Jo Vandesompele
Franki Speleman
Katleen De Preter
C3
Conference
2014
Reduced DICER1 functionality in neuroblastoma through reduced expression levels or somatic mutations
Bram De Wilde
Anneleen Beckers
Annelies Fieuw
Katleen De Preter
Pieter Mestdagh
Jo Vandesompele
Franki Speleman
C3
Conference
2014
Selecting potent antisense oligonucleotides for lncRNA knockdown using generalized additive models
Pieter-Jan Volders
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2014
Selecting potent antisense oligonucleotides for lncRNA silencing in vitro using thermodynamic properties and target RNA structure
Pieter-Jan Volders
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2014
Selection of reliable reference genes for RT-qPCR analysis
Jan Hellemans
Jo Vandesompele
Bookchapter
in
Qualntitative real-time PCR : methods and protocols
2014
Some cautionary notes on the petite 'Holy Grail' of molecular diagnostics
Jo Vandesompele
Pieter Mestdagh
Editorial material
2014
Target enrichment using parallel nanoliter quantitative PCR amplification
Bram De Wilde
Steve Lefever
Jo Vandesompele
A1
Journal Article
in
BMC GENOMICS
2014
Targeted analysis of TP53 pathway SNPs in neuroblastoma patients
Ali Rihani
Bram De Wilde
Fjoralba Zeka
Genevieve Laureys
Franki Speleman
Jo Vandesompele
Tom Van Maerken
C3
Conference
2014
The MYCN/miR-26a-5p/LIN28B regulatory axis controls MYCN-driven LIN28B upregulation in neuroblastoma
Anneleen Beckers
Gert Van Peer
Sara De Brouwer
Jo Vandesompele
Katleen De Preter
Franki Speleman
C3
Conference
2014
The MYCN/miR-26a-5p/LIN28B regulatory axis explains MYCN driven LIN28B upregulation during mouse neuroblastoma development
Anneleen Beckers
Gert Van Peer
Jo Vandesompele
Katleen De Preter
Franki Speleman
C3
Conference
2014
The NOTCH1 driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia
Annelynn Wallaert
Kaat Durinck
Pieter Rondou
Inge Van de Walle
Pieter-Jan Volders
Suzanne Vanhauwaert
Maté Ongenaert
Nadine Van Roy
Bruce Poppe
Yves Benoit
Jo Vandesompele
Pieter Van Vlierberghe
Tom Taghon
Franki Speleman
C3
Conference
2014
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia
Kaat Durinck
Annelynn Wallaert
Inge Van de Walle
Wouter Van Loocke
Pieter-Jan Volders
Suzanne Vanhauwaert
Yves Benoit
Nadine Van Roy
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
Pieter Rondou
Pieter Van Vlierberghe
Tom Taghon
Franki Speleman
A1
Journal Article
in
HAEMATOLOGICA
2014
The first lncRNA landscape of major genetic T-ALL subsets and guilt-by-association analysis for ETP-ALL specific lncRNAs
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Pieter-Jan Volders
Inge Van de Walle
Yves Benoit
Bruce Poppe
Jo Vandesompele
Tom Taghon
Pieter Rondou
Pieter Van Vlierberghe
Franki Speleman
C3
Conference
2014
The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
Jan Van Deun
Pieter Mestdagh
Lotte Pyfferoen
Karim Vermaelen
Veronique Cocquyt
Jo Vandesompele
Marc Bracke
Olivier De Wever
An Hendrix
C3
Conference
2014
The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
Jan Van Deun
Pieter Mestdagh
Veronique Cocquyt
Karim Vermaelen
Jo Vandesompele
Marc Bracke
Olivier De Wever
An Hendrix
A2
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2014
Time-resolved transcriptome analysis of TH-MYCN driven hyperplastic ganglia and tumors marks BRD3 as a novel candidate oncogene
Anneleen Beckers
Jo Vandesompele
Katleen De Preter
Franki Speleman
C3
Conference
2014
Unique lncRNA signatures mark the major T-ALL genetic subgroups
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Pieter-Jan Volders
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
Pieter Van Vlierberghe
Pieter Rondou
Franki Speleman
C3
Conference
2014
miRBase Tracker : keeping track of microRNA annotation changes
Gert Van Peer
Steve Lefever
Anneleen Beckers
Ali Rihani
Alan Van Goethem
Pieter-Jan Volders
Fjoralba Zeka
Maté Ongenaert
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
2014
2013
A bioinformatics analysis of renal miRNA- and mRNA-expression signatures in progressive chronic kidney disease
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2013
CLL cells respond to B-cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression
Valerie Pede
Ans Rombout
Jolien Vermeire
Evelien Naessens
Pieter Mestdagh
Hanne Vanderstraeten
Nadine Van Roy
Jo Vandesompele
Franki Speleman
Jan Philippé
Bruno Verhasselt
A1
Journal Article
in
PLOS ONE
2013
DNA methylation silences miR-132 in prostate cancer
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
ONCOGENE
2013
Dynamic regulation of miRNAs implicated in the MYCN-EZH2 regulatory axis during neuroblastoma tumor initiation and progression in a MYCN mouse model
Anneleen Beckers
Katleen De Preter
Gert Van Peer
Sara De Brouwer
Pieter Mestdagh
Genevieve Laureys
Jo Vandesompele
Franki Speleman
C3
Conference
2013
Effective Alu repeat based RT-qPCR normalization in cancer cell perturbation experiments
Ali Rihani
Tom Van Maerken
Filip Pattyn
Gert Van Peer
Anneleen Beckers
Sara De Brouwer
Candy Kumps
Evelien Mets
Joni Van der Meulen
Pieter Rondou
Carina Leonelli
Pieter Mestdagh
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
PLOS ONE
2013
Evaluation of qPCR curve analysis methods for reliable biomarker discovery: bias, resolution, precision, and implications
Katleen De Preter
Stefaan Derveaux
Jan Hellemans
Jo Vandesompele
A1
Journal Article
in
METHODS
2013
Expanding the TLX1 regulate in T-cell acute lymphoblastic leukemia towards long non-coding RNAs
Kaat Durinck
Joni Van der Meulen
Maté Ongenaert
Pieter-Jan Volders
Annelynn Wallaert
Nadine Van Roy
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
Pieter Rondou
Pieter Van Vlierberghe
Franki Speleman
C3
Conference
2013
Expanding the TLX1-regulome in T cell acute lymphoblastic leukemia towards long non-coding RNAs
Kaat Durinck
Joni Van der Meulen
Maté Ongenaert
Pieter-Jan Volders
Annelynn Wallaert
Nadine Van Roy
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
Pieter Rondou
Pieter Van Vlierberghe
Franki Speleman
C3
Conference
2013
Focal DNA copy number changes in neuroblastoma target MYCN regulated genes
Candy Kumps
Annelies Fieuw
Pieter Mestdagh
Björn Menten
Steve Lefever
Filip Pattyn
Sara De Brouwer
Tom Sante
Nadine Van Roy
Tom Van Maerken
Genevieve Laureys
Jo Vandesompele
Katleen De Preter
Franki Speleman
A1
Journal Article
in
PLOS ONE
2013
Genome wide expression, mutation and methylation analysis validates three new mouse models for neuroblastoma targeting MYCN, ALK and LIN28B for pre-clinical studies
Anneleen Beckers
Bram De Wilde
Maté Ongenaert
Candy Kumps
Jo Vandesompele
Katleen De Preter
Franki Speleman
C3
Conference
2013
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers
Anneleen Decock
Maté Ongenaert
Jasmien Hoebeeck
Katleen De Preter
Gert Van Peer
Wim Van Criekinge
Genevieve Laureys
Tom Van Maerken
Franki Speleman
Jo Vandesompele
C3
Conference
2013
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers
Anneleen Decock
Maté Ongenaert
Jasmien Hoebeeck
Katleen De Preter
Gert Van Peer
Wim Van Criekinge
Genevieve Laureys
Joëlle Vermeulen
Tom Van Maerken
Franki Speleman
Jo Vandesompele
C3
Conference
2013
High-throughput lncRNA expression profiling identifies candidate cancer lncRNAs
Pieter Mestdagh
Steve Lefever
Jo Vandesompele
C3
Conference
2013
Identification and functional characterization of lncRNAs in cancer
Pieter Mestdagh
Steve Lefever
Jo Vandesompele
C3
Conference
2013
Identification of miR-145 as a key regulator of the pigmentary process
Peter Dynoodt
Pieter Mestdagh
Gert Van Peer
Jo Vandesompele
Karen Goossens
Luc Peelman
Barbara Geusens
Reinhart Speeckaert
Jo Lambert
Mireille Van Gele
A1
Journal Article
in
JOURNAL OF INVESTIGATIVE DERMATOLOGY
2013
Identification of miRNAs implicated in neuroblastoma tumor initiation and progression through cross-species integrated genomic analysis
Anneleen Beckers
Katleen De Preter
Sara De Brouwer
Gert Van Peer
Pieter Mestdagh
Genevieve Laureys
Jo Vandesompele
Franki Speleman
C3
Conference
2013
Identifying and validating DNA methylation biomarkers: the example of neuroblastoma
Anneleen Decock
Maté Ongenaert
Jasmien Hoebeeck
Katleen De Preter
Gert Van Peer
Wim Van Criekinge
Genevieve Laureys
Joëlle Vermeulen
Tom Van Maerken
Franki Speleman
Jo Vandesompele
C3
Conference
2013
Improved outcome prediction of children with neuroblastoma using an integrated miRNA and DNA methylation signature
Anneleen Decock
Fjoralba Zeka
Katleen De Preter
Franki Speleman
Jo Vandesompele
C3
Conference
2013
LNCipedia 2.0: a database for annotated human lncRNA transcript sequences and structures
Pieter-Jan Volders
Kenny Helsens
Lennart Martens
Kris Gevaert
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2013
LNCipedia 2.0: a database for annotated human lncRNA transcript sequences and structures
Pieter-Jan Volders
Kenny Helsens
Lennart Martens
Kris Gevaert
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2013
LNCipedia : a database for annotated human lncRNA transcript sequences and structures
Pieter-Jan Volders
Kenny Helsens
Björn Menten
Lennart Martens
Kris Gevaert
Jo Vandesompele
Pieter Mestdagh
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2013
LNCipedia: a database for annotated human lncRNA transcript sequences and structures
Pieter-Jan Volders
Kenny Helsens
Lennart Martens
Kris Gevaert
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2013
MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells
Katleen De Preter
Steve Lefever
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
ONCOGENE
2013
MiR-128 is a novel PHF6 targeting regulatory non-coding RNA acting as a T-ALL oncogene
Evelien Mets
Joni Van der Meulen
Gert Van Peer
Pieter Mestdagh
Tom Taghon
Barbara De Moerloose
Yves Benoit
Bruce Poppe
Jo Vandesompele
Pieter Van Vlierberghe
Pieter Rondou
Franki Speleman
C3
Conference
2013
Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs
Pieter Mestdagh
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
ONCOGENE
2013
Of flies, mice and men : a systematic approach to understanding the early life origins of chronic lung disease
Guy Brusselle
Jo Vandesompele
A1
Journal Article
in
THORAX
2013
Reference loci for RT-qPCR analysis of differentiating human embryonic stem cells
Liesbeth Vossaert
Thomas O'Leary
Christophe Van Neste
Björn Heindryckx
Jo Vandesompele
Petra De Sutter
Dieter Deforce
A1
Journal Article
in
BMC MOLECULAR BIOLOGY
2013
Regulatory microRNA network identification in bovine blastocyst development
Karen Goossens
Pieter Mestdagh
Steve Lefever
Mario Van Poucke
Alex Van Zeveren
Ann Van Soom
Jo Vandesompele
Luc Peelman
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2013
Selective inhibition of the p53–MDM2 interaction by nutlin drugs: a new therapeutic perspective for neuroblastoma
Tom Van Maerken
Ali Rihani
Alan Van Goethem
Anne De Paepe
Franki Speleman
Jo Vandesompele
A2
Journal Article
in
PROCEEDINGS OF THE BELGIAN ROYAL ACADEMIES OF MEDICINE
2013
Single-nucleotide polymorphisms and other mismatches reduce performance of quantitative PCR assays
Steve Lefever
Filip Pattyn
Jan Hellemans
Jo Vandesompele
A1
Journal Article
in
CLINICAL CHEMISTRY
2013
The MYCN driven murine and human neuroblastoma methylome and dynamic regulation of chromatin regulators as a guide for epigenetic therapy
Anneleen Beckers
Anneleen Decock
Gert Van Peer
Sara De Brouwer
Genevieve Laureys
Jo Vandesompele
Maté Ongenaert
Katleen De Preter
Franki Speleman
C3
Conference
2013
The digital MIQE guidelines : minimum information for publication of quantitative digital PCR experiments
Jan Hellemans
Jo Vandesompele
A1
Journal Article
in
CLINICAL CHEMISTRY
2013
The need for transparency and good practices in the qPCR literature
Anneleen Beckers
Pieter Cornillie
Stephanie Coulon
Sara De Brouwer
Leentje De Ceuninck
Jurgen De Craene
Hélène De Naeyer
Ward De Spiegelaere
Annelies Dheedene
Kaat Durinck
Annelies Fieuw
Karen Goossens
Femke Heindryckx
Laura Icardi
Michail Karampelias
Candy Kumps
Irina Lambertz
Tim Lammens
Peter Messiaen
Evelien Mets
Hilde Nelis
Claudina Perez Novo
Ali Rihani
Pieter Rondou
Tim Van Acker
Wim Van Den Broeck
Joni Van der Meulen
Mireille Van Gele
Gert Van Peer
Mario Van Poucke
Nadine Van Roy
Sarah Vergult
Joris Wauman
Fjoralba Zeka
Jo Vandesompele
A1
Journal Article
in
NATURE METHODS
2013
miR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A
Anneleen Beckers
Pieter Mestdagh
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2013
miRNAs distinguish children with myelodysplastic syndrome from healthy donors
Hetty Helsmoortel
Tim Lammens
Pieter Mestdagh
Nadine Van Roy
Yves Benoit
Jo Vandesompele
Franki Speleman
Pieter Van Vlierberghe
Barbara De Moerloose
C3
Conference
2013
miRNAs distinguish children with myelodysplastic syndrome from healthy donors
Hetty Helsmoortel
Tim Lammens
Pieter Mestdagh
Nadine Van Roy
Yves Benoit
Jo Vandesompele
Franki Speleman
Pieter Van Vlierberghe
Barbara De Moerloose
C3
Conference
2013
2012
ALK(F1174L) is a driving oncogene of neuroblastoma in transgenic mice
Candy Kumps
Katleen De Preter
Bram De Wilde
Jo Vandesompele
Franki Speleman
C3
Conference
2012
Accurate RT-qPCR gene expression analysis on cell culture lysates
Gert Van Peer
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
SCIENTIFIC REPORTS
2012
Cancer gene prioritization for targeted resequencing using fitSNP scores
Annelies Fieuw
Bram De Wilde
Franki Speleman
Jo Vandesompele
Katleen De Preter
A1
Journal Article
in
PLOS ONE
2012
Development of bioinformatics tools for high-throughput PCR applications
Steve Lefever
Jo Vandesompele
Dissertation
2012
Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma
Sara De Brouwer
Pieter Mestdagh
Irina Lambertz
Filip Pattyn
Anne De Paepe
Katleen De Preter
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2012
Exon-level expression analyses identify MYCN and NTRK1 as major determinants of alternative exon usage and robustly predict primary neuroblastoma outcome
Jo Vandesompele
Joëlle Vermeulen
Katleen De Preter
Franki Speleman
A1
Journal Article
in
BRITISH JOURNAL OF CANCER
2012
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers.
Anneleen Decock
Maté Ongenaert
Jasmien Hoebeeck
Katleen De Preter
Gert Van Peer
Wim Van Criekinge
Genevieve Laureys
Joëlle Vermeulen
Tom Van Maerken
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
GENOME BIOLOGY
2012
Genomic profiling of MYCN and ALKF1174L transgenic neuroblastoma mouse models provides insights into the dynamic process of tumor formation
Katleen De Preter
Anneleen Beckers
Candy Kumps
Pieter Mestdagh
Jo Vandesompele
Franki Speleman
C3
Conference
2012
Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas
Annelies Fieuw
Candy Kumps
Filip Pattyn
Björn Menten
Nadine Van Roy
Sarah Vergult
Anne De Paepe
Jo Vandesompele
Katleen De Preter
Franki Speleman
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2012
Improved risk stratification and outcome prediction in children with average risk 1 precursor-B acute lymphoblastic leukemia using a 19-microRNA signature
Farzaneh Ghazavi
Tim Lammens
Genevieve Laureys
Joni Van der Meulen
Pieter Mestdagh
Jo Vandesompele
Franki Speleman
Barbara De Moerloose
Yves Benoit
C3
Conference
2012
Improved risk-stratification and outcome prediction in children with average risk precursor-B acute lymphoblastic leukemia using a 19-microRNA signature
Farzaneh Ghazavi
Tim Lammens
Genevieve Laureys
Joni Van der Meulen
Pieter Mestdagh
Jo Vandesompele
Franki Speleman
Barbara De Moerloose
Yves Benoit
C3
Conference
2012
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
Bram De Wilde
Jo Vandesompele
A1
Journal Article
in
NATURE GENETICS
2012
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
Pieter Mestdagh
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
NATURE GENETICS
2012
LNCipedia: a novel databse for annotated lncRNA sequences and structures
Pieter-Jan Volders
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2012
Large-scale and targeted genomic screen reveals focal lncRNA copy number alterations in cancer cells
Pieter-Jan Volders
Pieter Mestdagh
Björn Menten
Jo Vandesompele
C3
Conference
2012
Lncipedia: a novel database for annotated lncRNA sequences and structures
Pieter-Jan Volders
Kenny Helsens
Lennart Martens
Kris Gevaert
Jo Vandesompele
Pieter Mestdagh
C3
Conference
2012
Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation
Pieter Mestdagh
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
LEUKEMIA
2012
MYCN directly regulates long non-coding RNA expression in neuroblastoma
Pieter Mestdagh
Filip Pattyn
Genevieve Laureys
Franki Speleman
Jo Vandesompele
C3
Conference
2012
Mapping the neuroblastoma epigenome
Maté Ongenaert
Anneleen Decock
Jo Vandesompele
Franki Speleman
C3
Conference
2012
Mapping the neuroblastoma epigenome: perspectives for improved prognostic biomarkers
Maté Ongenaert
Anneleen Decock
Genevieve Laureys
Jo Vandesompele
Franki Speleman
C3
Conference
2012
Mapping the neuroblastoma epigenome: perspectives for improved prognostic biomarkers
Maté Ongenaert
Anneleen Decock
Jo Vandesompele
Franki Speleman
C3
Conference
2012
Massively parallel sequencing for early molecular diagnosis in Leber congenital amaurosis
Frauke Coppieters
Bram De Wilde
Steve Lefever
Ellen De Meester
Nina De Rocker
Caroline Van Cauwenbergh
Filip Pattyn
Bart Leroy
Jan Hellemans
Jo Vandesompele
Elfride De Baere
A1
Journal Article
in
GENETICS IN MEDICINE
2012
Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform
Sarah De Keulenaer
Jan Hellemans
Steve Lefever
Jean-Pierre Renard
Joachim De Schrijver
Hendrik Van de Voorde
Filip Van Nieuwerburgh
Daisy Flamez
Filip Pattyn
Bieke Scharlaken
Dieter Deforce
Sofie Bekaert
Wim Van Criekinge
Jo Vandesompele
Paul Coucke
A1
Journal Article
in
BMC MEDICAL GENOMICS
2012
N-Cadherin in neuroblastoma disease : expression and clinical significance
Tim Lammens
Katrien Swerts
Lara Derycke
Sara De Brouwer
Katleen De Preter
Nadine Van Roy
Jo Vandesompele
Franki Speleman
Jan Philippé
Yves Benoit
Marc Bracke
Genevieve Laureys
A1
Journal Article
in
PLOS ONE
2012
Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma
Jo Vandesompele
A1
Journal Article
in
ONCOGENE
2012
Promoter methylation analysis identifies prognostic methylation biomarkers in neuroblastoma
Anneleen Decock
Maté Ongenaert
Jasmien Hoebeeck
Katleen De Preter
Gert Van Peer
Wim Van Criekinge
Genevieve Laureys
Joëlle Vermeulen
Tom Van Maerken
Franki Speleman
Jo Vandesompele
C3
Conference
2012
Semi-high-throughput epigenetic validation using MSP on a real-time qPCR platform
Anneleen Decock
Maté Ongenaert
Jo Vandesompele
Franki Speleman
C3
Conference
2012
Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation
David Nittner
Irina Lambertz
Pieter Mestdagh
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
NATURE CELL BIOLOGY
2012
Targeted expression of mutated ALK induces neuroblastoma in transgenic mice
Katleen De Preter
Candy Kumps
Bram De Wilde
Filip Pattyn
Pieter Mestdagh
Björn Menten
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
SCIENCE TRANSLATIONAL MEDICINE
2012
Whole-genome RT-qPCR microRNA expression profiling
Pieter Mestdagh
Stefaan Derveaux
Jo Vandesompele
Bookchapter
in
Functional genomics : methods and protocols
2012
miRNA expression profiling: from reference genes to global mean normalization
Pieter Mestdagh
Jo Vandesompele
Bookchapter
in
Next-generation microRNA expression profiling technology : methods and protocols
2012
microRNAs in colon cancer : a roadmap for discovery
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
FEBS LETTERS
2012
2011
EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells
An De Weer
Joni Van der Meulen
Pieter Rondou
Tom Taghon
Katleen De Preter
Pieter Mestdagh
Tom Van Maerken
Nadine Van Roy
Lucien Noens
Anne De Paepe
Bruno Verhasselt
Jan Philippé
Jo Vandesompele
Pieter Van Vlierberghe
Bruce Poppe
Franki Speleman
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2011
Ewings sarcoma and prostate cancer: different yet similar
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2011
Exploring the neuroblastoma methylome using MBD2-seq
Maté Ongenaert
Anneleen Decock
Jo Vandesompele
Franki Speleman
C3
Conference
2011
Functional analysis of the p53 pathway in neuroblastoma cells using the small-molecule MDM2 antagonist Nutlin-3
Tom Van Maerken
Ali Rihani
Sarah De Clercq
Nurten Yigit
Jean-Christophe Marine
Anne De Paepe
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
MOLECULAR CANCER THERAPEUTICS
2011
High ALK receptor tyrosine kinase expression supersedes ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma
Katleen De Preter
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2011
Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcoma
Pieter Mestdagh
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
ONCOGENE
2011
Identification of a new rare recurrent 1q42.2-qter deletion in neuroblastoma
Annelies Fieuw
Candy Kumps
Björn Menten
Nadine Van Roy
Sarah Vergult
Jo Vandesompele
Katleen De Preter
Franki Speleman
C3
Conference
2011
Mapping the neuroblastoma epigenome
Maté Ongenaert
Anneleen Decock
Jo Vandesompele
Franki Speleman
C3
Conference
2011
Measurable impact of RNA quality on gene expression results from quantitative PCR
Joëlle Vermeulen
Katleen De Preter
Steve Lefever
Justine Nuytens
Fanny De Vloed
Stefaan Derveaux
Jan Hellemans
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2011
MicroRNA expression in induced sputum of smokers and patients with chronic obstructive pulmonary disease
Geert Van Pottelberge
Pieter Mestdagh
Ken Bracke
Olivier Thas
Yannick van Durme
Guy Joos
Jo Vandesompele
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2011
MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival
Pieter Mestdagh
Candy Kumps
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2011
Molecular portraits of non-coding RNAs in neuroblastoma
Pieter Mestdagh
Jo Vandesompele
Franki Speleman
Dissertation
2011
Neuroblastoma epigenetics : from candidate gene approaches to genome-wide screenings
Anneleen Decock
Maté Ongenaert
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
EPIGENETICS
2011
Neuroblastoma genetics and phenotype: a tale of heterogeneity
Franki Speleman
Katleen De Preter
Jo Vandesompele
A1
Journal Article
in
SEMINARS IN CANCER BIOLOGY
2011
New options for molecular therapy of neuroblastoma: from p53 to gene therapy
Tom Van Maerken
Franki Speleman
Jo Vandesompele
Dissertation
2011
Pharmacological activation of p53 and gene therapy as emerging treatment options for neuroblastoma
Tom Van Maerken
Ali Rihani
Anne De Paepe
Jo Vandesompele
Franki Speleman
A2
Journal Article
in
BELGIAN JOURNAL OF MEDICAL ONCOLOGY
2011
Pharmacological activation of the p53 pathway by nutlin-3 inhibits medulloblastoma cell proliferation in vitro and in vivo
Katleen De Preter
Jo Vandesompele
C3
Conference
2011
Practical tools to implement massive parallel pyrosequencing of PCR products in next generation molecular diagnostics
Kim De Leeneer
Joachim De Schrijver
Lieven Clement
Machteld Baetens
Steve Lefever
Sarah De Keulenaer
Wim Van Criekinge
Dieter Deforce
Filip Van Nieuwerburgh
Sofie Bekaert
Filip Pattyn
Bram De Wilde
Paul Coucke
Jo Vandesompele
Kathleen Claes
Jan Hellemans
A1
Journal Article
in
PLOS ONE
2011
Primer sequence disclosure : a clarification of the MIQE guidelines
Jan Hellemans
Jo Vandesompele
A1
Journal Article
in
CLINICAL CHEMISTRY
2011
Regulatory networks governed by microRNAs in T-ALL oncogenesis and normal T-cell development
Joni Van der Meulen
Evelien Mets
Pieter Mestdagh
Peter Pipelers
Tom Taghon
Gert Van Peer
Nadine Van Roy
Olivier Thas
Yves Benoit
Jo Vandesompele
Bruce Poppe
Pieter Van Vlierberghe
Pieter Rondou
Franki Speleman
C3
Conference
2011
Selectieve inhibitie van de p53–MDM2 interactie door nutlin-3 als een nieuwe therapeutische strategie voor neuroblastoom
Tom Van Maerken
Ali Rihani
Anne De Paepe
Jo Vandesompele
Franki Speleman
A2
Journal Article
in
TIJDSCHRIFT VAN DE BELGISCHE KINDERARTS = JOURNAL DU PEDIATRE BELGE
2011
Semi-high throughput epigenetic validation using MSP on a real-time qPCR platform
Anneleen Decock
Maté Ongenaert
Jo Vandesompele
Franki Speleman
C3
Conference
2011
Semi-high throughput epigenetic validation using MSP on a real-time qPCR platform
Anneleen Decock
Maté Ongenaert
Jo Vandesompele
Franki Speleman
C3
Conference
2011
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma
Pieter Mestdagh
Francis Impens
Gert Van Peer
Bart Ghesquière
Kris Gevaert
Franki Speleman
Jo Vandesompele
C3
Conference
2011
The microRNA body map : dissecting microRNA function through integrative genomics
Pieter Mestdagh
Steve Lefever
Filip Pattyn
Annelies Fieuw
Maté Ongenaert
Joëlle Vermeulen
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2011
miRNA Expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples
Katleen De Preter
Pieter Mestdagh
Joëlle Vermeulen
Fjoralba Zeka
Genevieve Laureys
Nadine Van Roy
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2011
2010
Accurate Outcome Prediction in Neuroblastoma across Independent Data Sets Using a Multigene Signature
Katleen De Preter
Joëlle Vermeulen
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2010
Accurate and objective copy number profiling using real-time quantitative PCR
Jo Vandesompele
Jan Hellemans
A1
Journal Article
in
METHODS
2010
Accurate prediction of neuroblastoma outcome based on miRNA expression profiles
Pieter Mestdagh
Joëlle Vermeulen
Katleen De Preter
Franki Speleman
Jo Vandesompele
C3
Conference
2010
Accurate prediction of neuroblastoma outcome based on miRNA expression profiles
Pieter Mestdagh
Joëlle Vermeulen
Katleen De Preter
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2010
An integrated genomics approach unravels a role for micro-RNAs in EWS-FLI1 driven Ewings sarcoma pathogenesis
Pieter Mestdagh
Franki Speleman
Jo Vandesompele
C3
Conference
2010
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours
Pieter Mestdagh
Filip Pattyn
Ali Rihani
Tom Van Maerken
Joëlle Vermeulen
Candy Kumps
Björn Menten
Katleen De Preter
Genevieve Laureys
David Nittner
Jean-Christophe Marine
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
ONCOGENE
2010
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours
Pieter Mestdagh
Filip Pattyn
Ali Rihani
Tom Van Maerken
Joëlle Vermeulen
Candy Kumps
Björn Menten
Katleen De Preter
Genevieve Laureys
Franki Speleman
Jo Vandesompele
C3
Conference
2010
Analysing 454 amplicon resequencing experiments using the modular and database oriented Variant Identification Pipeline
Joachim De Schrijver
Kim De Leeneer
Steve Lefever
Nick Sabbe
Filip Pattyn
Filip Van Nieuwerburgh
Paul Coucke
Dieter Deforce
Jo Vandesompele
Sofie Bekaert
Jan Hellemans
Wim Van Criekinge
A1
Journal Article
in
BMC BIOINFORMATICS
2010
Chromosomal and microRNA expression patterns reveal biologically distinct subgroups of 11q- neuroblastoma
Pieter Mestdagh
Katleen De Preter
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2010
Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2010
Deep sequencing reveals differential expression of microRNAs in favourable versus unfavourable neuroblastoma
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2010
Different mucosal expression of Th17 related genes in the small and large bowel of IBD patients
Debby Laukens
Harald Peeters
Lode Melis
Kim Olievier
Nico Boon
Jo Vandesompele
Dirk Elewaut
Martine De Vos
C3
Conference
2010
Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease
Sara Bogaert
Debby Laukens
Harald Peeters
Lode Melis
Kim Olievier
Nico Boon
August Verbruggen
Jo Vandesompele
Dirk Elewaut
Martine De Vos
A1
Journal Article
in
BMC IMMUNOLOGY
2010
Exploring 3D pooled next-generation sequencing using SNP-Cub^3
Joachim De Schrijver
Bram De Wilde
Geert Trooskens
Jo Vandesompele
Wim Van Criekinge
C3
Conference
2010
High expression of the ALK receptor tyrosine kinase precedes mutation as a determining factor of unfavourable phenotype in primary neuroblastoma
Katleen De Preter
Franki Speleman
Jo Vandesompele
C3
Conference
2010
How to do successful gene expression analysis using real-time PCR
Stefaan Derveaux
Jo Vandesompele
Jan Hellemans
A1
Journal Article
in
METHODS
2010
Improved Molecular Diagnostics of Idiopathic Short Stature and Allied Disorders: Quantitative Polymerase Chain Reaction-Based Copy Number Profiling of SHOX and Pseudoautosomal Region 1
Jan Hellemans
Margarita Craen
Jean De Schepper
Eveline Debals
Anne De Paepe
Geert Mortier
Jo Vandesompele
Elfride De Baere
A1
Journal Article
in
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
2010
MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors
Pieter Mestdagh
Filip Pattyn
Joëlle Vermeulen
Candy Kumps
Katleen De Preter
Nadine Van Roy
Genevieve Laureys
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
ONCOGENE
2010
Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification
Sara De Brouwer
Katleen De Preter
Candy Kumps
Jo Vandesompele
Jasmien Hoebeeck
Tom Van Maerken
Anne De Paepe
Genevieve Laureys
Joëlle Vermeulen
Nadine Van Roy
Franki Speleman
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2010
MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
BMC CANCER
2010
Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo
Irina Lambertz
David Nittner
Pieter Mestdagh
Geertrui Denecker
Jo Vandesompele
Jean-Christophe Marine
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2010
Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma
Candy Kumps
Nadine Van Roy
Jo Vandesompele
Franki Speleman
Katleen De Preter
A1
Journal Article
in
BMC GENOMICS
2010
Next generation sequencing: (r)evolutie in DNA sequenering en haar rol in de moderne geneeskunde
Jan Hellemans
Sofie Bekaert
Jo Vandesompele
Paul Coucke
Anne De Paepe
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2010
Pharmacologic activation of the P53 pathway by Nutlin-3 inhibits medulloblastoma cell proliferation in vitro
Katleen De Preter
Jo Vandesompele
C3
Conference
2010
Predicting outcomes for children with neuroblastoma
Joëlle Vermeulen
Katleen De Preter
Pieter Mestdagh
Genevieve Laureys
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
DISCOVERY MEDICINE
2010
Prognostic impact of gene expression-based classification for neuroblastoma
Jo Vandesompele
Joëlle Vermeulen
Franki Speleman
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2010
The miR-17-92 MicroRNA Cluster regulates multiple components of the TGF-beta Pathway in neuroblastoma
Pieter Mestdagh
Francis Impens
Gert Van Peer
Bart Ghesquière
Kris Gevaert
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
MOLECULAR CELL
2010
The miRNA body map: dissecting miRNA function through integrative genomics
Pieter Mestdagh
Steve Lefever
Filip Pattyn
Annelies Fieuw
Joëlle Vermeulen
Anne De Paepe
Franki Speleman
Jo Vandesompele
C3
Conference
2010
methGraph: A genome visualization tool for PCR-based methylation assays
Steve Lefever
Jasmien Hoebeeck
Filip Pattyn
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
EPIGENETICS
2010
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
Pieter Mestdagh
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
NATURE CELL BIOLOGY
2010
mir-17-92 is a master regulator of TGFβ-pathway activity in neuroblastoma
Pieter Mestdagh
Francis Impens
Bart Ghesquière
Kris Gevaert
Franki Speleman
Jo Vandesompele
C3
Conference
2010
2009
59-gene prognostic signature sub-stratifies high-risk neuroblastoma patients
Joëlle Vermeulen
Katleen De Preter
Genevieve Laureys
Franki Speleman
Jo Vandesompele
Editorial material
2009
A novel and universal method for microRNA RT-qPCR data normalization
Pieter Mestdagh
Pieter Van Vlierberghe
An De Weer
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
GENOME BIOLOGY
2009
ALK Mutation Analysis in Patients of the German Neuroblastoma Study
Pieter Mestdagh
Jo Vandesompele
C3
Conference
2009
Aberrant methylation of candidate tumor suppressor genes in neuroblastoma
Jasmien Hoebeeck
Evi Michels
Filip Pattyn
Nurten Yigit
Genevieve Laureys
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
CANCER LETTERS
2009
Amphiregulin and Epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with Cetuximab
Jo Vandesompele
Marc Peeters
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2009
An assessment of air as a source of DNA contamination encountered when performing PCR
Jo Vandesompele
A2
Journal Article
in
Journal of biomolecular techniques
2009
Antitumor Activity of the Selective MDM2 Antagonist Nutlin-3 Against Chemoresistant Neuroblastoma With Wild-Type p53
Tom Van Maerken
Liesbeth Ferdinande
Jasmien Taildeman
Irina Lambertz
Nurten Yigit
Liesbeth Vercruysse
Ali Rihani
Claude Cuvelier
Jean-Christophe Marine
Anne De Paepe
Marc Bracke
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
JOURNAL OF THE NATIONAL CANCER INSTITUTE
2009
Chromosome 3p microsatellite allelotyping in neuroblastoma: a report on the technical hurdles
Jasmien Hoebeeck
Bram De Wilde
Evi Michels
Nurten Yigit
Els De Smet
Nadine Van Roy
Genevieve Laureys
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
CANCER INVESTIGATION
2009
Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs
Pieter Van Vlierberghe
An De Weer
Pieter Mestdagh
Katleen De Preter
Anne De Paepe
Kathleen Lambein
Jo Vandesompele
Nadine Van Roy
Bruno Verhasselt
Bruce Poppe
Franki Speleman
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2009
Correlation between porcine PPARGC1A mRNA expression and its downstream target genes in backfat and longissimus dorsi muscle
Tim Erkens
Jo Vandesompele
Alex Van Zeveren
Luc Peelman
A1
Journal Article
in
JOURNAL OF APPLIED GENETICS
2009
Downregulation of miR-449a is essential for the survival of EVI1 positive leukemic cells through modulation of NOTCH1 and BCL2
An De Weer
Pieter Mestdagh
Katleen De Preter
Joni Van der Meulen
Pieter Van Vlierberghe
Tom Van Maerken
Nadine Van Roy
Lucien Noens
Anne De Paepe
Bruno Verhasselt
Jan Philippé
Jo Vandesompele
Bruce Poppe
Franki Speleman
C3
Conference
2009
EFFECT OF ZAP-70 ON MIRNA EXPRESSION PROFILE IN CHRONIC LYMPHOCYTIC LEUKEMIA
Valerie Pede
Jan Philippé
Pieter Mestdagh
Jo Vandesompele
Bruno Verhasselt
C3
Conference
2009
Escape from p53-mediated tumor surveillance in neuroblastoma: switching off the p14(ARF)-MDM2-p53 axis
Tom Van Maerken
Jo Vandesompele
Ali Rihani
Anne De Paepe
Franki Speleman
A1
Journal Article
in
Cell Death & Differentiation
2009
External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data
Joëlle Vermeulen
Filip Pattyn
Katleen De Preter
Liesbeth Vercruysse
Stefaan Derveaux
Pieter Mestdagh
Steve Lefever
Jan Hellemans
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2009
Gebruik van genexpresieanalyse in de aanpak van neuroblastoom bij kinderen
Joëlle Vermeulen
Katleen De Preter
Pieter Mestdagh
Filip Pattyn
Anne De Paepe
Nadine Van Roy
Genevieve Laureys
Franki Speleman
Jo Vandesompele
A4
Journal Article
in
ONCO (NEDERLANDSE ED.)
2009
Gene expression of PPARGC1A and several downstream target genes in porcine backfat and longissimus dorsi muscle
Tim Erkens
Jo Vandesompele
Mario Van Poucke
Alex Van Zeveren
Luc Peelman
C3
Conference
2009
Genetic analysis of PRNP, SPRN and RPSA in relation to prion disease resistance in sheep
Mario Van Poucke
Evelyne Lampo
Alice Van den Broeke
Dominique Vander Donckt
Carolien Rogiers
Tim Erkens
Karen Goossens
Jo Vandesompele
Alex Van Zeveren
Luc Peelman
C3
Conference
2009
Improved outcome prediction of children with neuroblastoma using a multigene expression signature
Joëlle Vermeulen
Jo Vandesompele
Franki Speleman
Dissertation
2009
MICRORNA SIGNATURES IN GENETIC SUBTYPES OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Joni Van der Meulen
Pieter Van Vlierberghe
Pieter Mestdagh
Jo Vandesompele
Bruce Poppe
Nadine Van Roy
Tom Taghon
Jean Plum
Barbara De Moerloose
Yves Benoit
Anne De Paepe
Franki Speleman
C3
Conference
2009
MODULATION OF MIR-449A EXPRESSION DECREASES CELL VIABILITY, INCREASES APOPTOSIS AND INDUCES DIFFERENTIATION IN EVI1 DEREGULATED LEUKEMIA CELLS
An De Weer
Bruce Poppe
Pieter Mestdagh
Katleen De Preter
Pieter Van Vlierberghe
Nadine Van Roy
Bruno Verhasselt
Jan Philippé
Lucien Noens
Anne De Paepe
Jo Vandesompele
Franki Speleman
C3
Conference
2009
Meta-mining of Neuroblastoma and Neuroblast Gene Expression Profiles Reveals Candidate Therapeutic Compounds
Katleen De Preter
Sara De Brouwer
Tom Van Maerken
Filip Pattyn
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2009
Modeling neuroblastomagenesis from neural crest stem cells in vitro and in vivo
Katleen De Preter
Jo Vandesompele
Franki Speleman
C3
Conference
2009
Positive correlation between relative mRNA expression of PRNP and SPRN in cerebral and cerebellar cortex of sheep
Evelyne Lampo
Mario Van Poucke
Jo Vandesompele
Tim Erkens
Alex Van Zeveren
Luc Peelman
A1
Journal Article
in
Molecular and Cellular Probes
2009
Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study
Joëlle Vermeulen
Katleen De Preter
Liesbeth Vercruysse
Nadine Van Roy
Jan Hellemans
Katrien Swerts
Genevieve Laureys
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
LANCET ONCOLOGY
2009
Prognostic role and functional analyses of miRNA expression in neuroblastoma
Pieter Mestdagh
Katleen De Preter
Jo Vandesompele
C3
Conference
2009
RDML : structured language and reporting guidelines for real-time quantitative PCR data
Steve Lefever
Jan Hellemans
Filip Pattyn
Jo Vandesompele
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2009
RNA pre-amplification enables large-scale RT-qPCR gene-expression studies on limiting sample amounts
Joëlle Vermeulen
Stefaan Derveaux
Steve Lefever
Els De Smet
Katleen De Preter
Nurten Yigit
Anne De Paepe
Filip Pattyn
Franki Speleman
Jo Vandesompele
A2
Journal Article
in
BMC RESEARCH NOTES
2009
RTPrimerDB : the portal for real-time PCR primers and probes
Steve Lefever
Jo Vandesompele
Franki Speleman
Filip Pattyn
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2009
Risk estimation of neuroblastoma patients by gene expression based classification
Jo Vandesompele
Franki Speleman
C3
Conference
2009
Selection of reference genes for quantitative real-time PCR in equine in vivo and in vitro blastocysts
Katrien Smits
Karen Goossens
Ann Van Soom
Jan Govaere
Maarten Hoogewijs
Jo Vandesompele
Luc Peelman
A2
Journal Article
in
BMC RESEARCH NOTES
2009
Standardization of qPCR and RT-qPCR
Jo Vandesompele
A1
Journal Article
in
GENETIC ENGINEERING & BIOTECHNOLOGY NEWS
2009
The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments
Jan Hellemans
Jo Vandesompele
A1
Journal Article
in
CLINICAL CHEMISTRY
2009
The emerging molecular pathogenesis of neuroblastoma : implications for improved risk assessment and targeted therapy
Nadine Van Roy
Katleen De Preter
Jasmien Hoebeeck
Tom Van Maerken
Filip Pattyn
Pieter Mestdagh
Joëlle Vermeulen
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
GENOME MEDICINE
2009
The miR-17-92 gene cluster is amplified and overexpressed in retinoblastoma
Pieter Mestdagh
Katleen De Preter
Franki Speleman
Jo Vandesompele
C3
Conference
2009
The miR-17-92 gene cluster is amplified and overexpressed in retinoblastoma
Pieter Mestdagh
Katleen De Preter
Franki Speleman
Jo Vandesompele
C3
Conference
2009
Unreliable Real-Time PCR Analysis of Human Endogenous Retrovirus-W (HERV-W) RNA Expression and DNA Copy Number in Multiple Sclerosis
Jo Vandesompele
A1
Journal Article
in
AIDS RESEARCH AND HUMAN RETROVIRUSES
2009
Using real-time qPCR to evaluate RNAi-mediated gene silencing
Tom Van Maerken
Pieter Mestdagh
Filip Pattyn
Nurten Yigit
Anne De Paepe
Franki Speleman
Jo Vandesompele
A2
Journal Article
in
BioTechniques Protocol Guide
2009
Widespread dysregulation of MiRNAs by MYCN amplification and chromosomal imbalances in neuroblastoma: association of miRNA expression with survival
Pieter Mestdagh
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
PLoS One
2009
2008
A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes
Karl Vandepoele
Vanessa Andries
Nadine Van Roy
Katrien Staes
Jo Vandesompele
Genevieve Laureys
Els De Smet
Geert Berx
Franki Speleman
Frans Van Roy
A1
Journal Article
in
PLOS ONE
2008
A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the the human NBPF1 and ACCN1 genes
Frans Van Roy
Klaas Vandepoele
Nadine Van Roy
Vanessa Andries
Katrien Staes
Jo Vandesompele
Genevieve Laureys
Els De Smet
Geert Berx
Franki Speleman
C3
Conference
2008
Aberrant splicing of the PTPRD gene mimics microdeletions identified at this locus in neuroblastomas (vol 47, pg 197, 2008)
Katleen De Preter
Jo Vandesompele
Franki Speleman
Correction
2008
Aberrant splicing of the PTPRD gene mimics microdeletions identified-at locus this in neuroblastomas
Katleen De Preter
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2008
CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23
Evi Michels
Jasmien Hoebeeck
Katleen De Preter
Anne De Paepe
Genevieve Laureys
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
BMC CANCER
2008
Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas
Jo Vandesompele
Filip Pattyn
A1
Journal Article
in
GENOME BIOLOGY
2008
Expression profiling of a new class of non-coding RNAs in human neuroblastoma
Pieter Mestdagh
Filip Pattyn
Katleen De Preter
Joëlle Vermeulen
Anne De Paepe
Franki Speleman
Jo Vandesompele
C3
Conference
2008
Gene sets enrichment analysis of chromosomal regions
Katleen De Preter
Franki Speleman
Jo Vandesompele
C3
Conference
2008
High resolution genome analysis for improved prognostic stratification and candidate gene selection in neuroblastoma
Evi Michels
Franki Speleman
Jo Vandesompele
Dissertation
2008
High throughput stem-loop RT-PCR miRNA expression profiling using minute amounts of input RNA reveals new insights in neuroblastoma pathogenesis
Pieter Mestdagh
Joëlle Vermeulen
Katleen De Preter
Filip Pattyn
Genevieve Laureys
Franki Speleman
Jo Vandesompele
C3
Conference
2008
High-throughput stem-loop RT-PCR miRNA expression profiling using minute amounts of input RNA
Pieter Mestdagh
Franki Speleman
Jo Vandesompele
C3
Conference
2008
High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA
Pieter Mestdagh
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2008
Identification of 2 putative critical segments of 17q gain in neuroblastoma through integrative genomics
Jo Vandesompele
Evi Michels
Katleen De Preter
Björn Menten
Anne De Paepe
Genevieve Laureys
Franki Speleman
Nadine Van Roy
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2008
Low-cost dedicated mini-arrays for high-throughput analysis of DNA copy-number alterations in neuroblastoma
Katleen De Preter
Björn Menten
Sara De Brouwer
Candy Kumps
Evi Michels
Nadine Van Roy
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
CANCER LETTERS
2008
MICRORNA PROFILING OF EVI1 DEREGULATED MYELOID LEUKEMIA
An De Weer
Bruce Poppe
Pieter Mestdagh
Pieter Van Vlierberghe
Nadine Van Roy
Anne De Paepe
Bruno Verhasselt
Jo Vandesompele
Franki Speleman
C3
Conference
2008
MYCN regulates oncogenic and tumour suppressor miRNA networks in neuroblastoma
Pieter Mestdagh
Joëlle Vermeulen
Filip Pattyn
Anne De Paepe
Genevieve Laureys
Franki Speleman
Jo Vandesompele
C3
Conference
2008
Positional gene enrichment analysis of gene sets for high-resolution identification of overrepresented chromosomal regions
Katleen De Preter
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2008
Positive correlation between relative mRNA expression of PRNP and SPRN in cerebral cortex of sheep
Evelyne Lampo
Mario Van Poucke
Jo Vandesompele
Tim Erkens
Alex Van Zeveren
Luc Peelman
C3
Conference
2008
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project
Jo Vandesompele
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2008
Real-time qPCR as a tool for evaluating RNAi-mediated gene silencing
Tom Van Maerken
Pieter Mestdagh
Sarah De Clercq
Filip Pattyn
Nurten Yigit
Anne De Paepe
Jean-Christophe Marine
Franki Speleman
Jo Vandesompele
A2
Journal Article
in
Bioradiations
2008
Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C-elegans
David Hoogewijs
Koen Houthoofd
Filip Matthijssens
Jo Vandesompele
Jacques Vanfleteren
A1
Journal Article
in
BMC MOLECULAR BIOLOGY
2008
Standardization of real-time PCR gene expression data from independent biological replicates
Jo Vandesompele
Editorial material
2008
Unmasking of epigenetically silenced microRNAs in neuroblastoma
Jasmien Hoebeeck
Geert Declerck
Pieter Mestdagh
Filip Pattyn
Katleen De Preter
Joëlle Vermeulen
Nurten Yigit
Anne De Paepe
Franki Speleman
Jo Vandesompele
C3
Conference
2008
2007
Array CGH analysis of subnanogram quantities of DNA using whole genome amplification: opportunities for detection of copy number alterations in Hodgkin's lymphoma
Tom Feys
Bruno Verhasselt
Björn Menten
Jo Vandesompele
Nadine Van Roy
Anne De Paepe
Franki Speleman
C3
Conference
2007
ArrayCGH based classification of neuroblastoma into genomic subgroups
Sara De Brouwer
Evi Michels
Jo Vandesompele
Katleen De Preter
Jasmien Hoebeeck
Joëlle Vermeulen
Björn Menten
Anne De Paepe
Genevieve Laureys
Nadine Van Roy
Franki Speleman
C3
Conference
2007
ArrayCGH-based classification of neuroblastoma into genomic subgroups
Evi Michels
Jo Vandesompele
Katleen De Preter
Jasmien Hoebeeck
Joëlle Vermeulen
Björn Menten
Anne De Paepe
Genevieve Laureys
Nadine Van Roy
Franki Speleman
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2007
Genome wide promoter methylation analysis in neuroblastoma with perspectives for integrated molecular profiling
Jasmien Hoebeeck
Maté Ongenaert
Evi Michels
Katleen De Preter
Joëlle Vermeulen
Nurten Yigit
Anne De Paepe
Wim Van Criekinge
Franki Speleman
Jo Vandesompele
C3
Conference
2007
Genomic classification according to numerical and segmental chromosome instabilities is of strong prognostic relevance in neuroblastoma
Joëlle Vermeulen
Jo Vandesompele
C3
Conference
2007
High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors
Jasmien Hoebeeck
Evi Michels
Björn Menten
Nadine Van Roy
Katleen De Preter
Nurten Yigit
Els De Smet
Anne De Paepe
Genevieve Laureys
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2007
Identification and expression analysis of genes associated with bovine blastocyst formation
Karen Goossens
Ann Van Soom
Mario Van Poucke
Leen Vandaele
Jo Vandesompele
Alex Van Zeveren
Luc Peelman
A1
Journal Article
in
BMC DEVELOPMENTAL BIOLOGY
2007
Integrative genomics in neuroblastoma research
Franki Speleman
Katleen De Preter
Evi Michels
Jasmien Hoebeeck
Filip Pattyn
Joëlle Vermeulen
Nadine Van Roy
Anne De Paepe
Genevieve Laureys
Jo Vandesompele
C3
Conference
2007
MicroRNA profiling of EVI1 deregulated myeloid leukemia
An De Weer
Bruce Poppe
Pieter Mestdagh
Nadine Van Roy
Anne De Paepe
Bruno Verhasselt
Jo Vandesompele
Franki Speleman
C3
Conference
2007
Molecular dissection of isolated disease features in mosaic neurofibromatosis type 1
Ophélia Maertens
Sofie De Schepper
Jo Vandesompele
Sandra Janssens
Franki Speleman
A1
Journal Article
in
AMERICAN JOURNAL OF HUMAN GENETICS
2007
New insights into the genetic basis of neuroblastoma
Franki Speleman
Katleen De Preter
Jasmien Hoebeeck
Nadine Van Roy
Jo Vandesompele
A4
Journal Article
in
VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË
2007
Rapid and easy prenatal diagnosis of sickle cell anemia using double-dye LNA probe technology
Jo Vandesompele
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2007
Real-time PCR quality control for gene expression profiling on the LightCycler 480 System
Jasmien Hoebeeck
Filip Pattyn
Franki Speleman
Jo Vandesompele
A3
Journal Article
in
Biochemica
2007
Real-time quantitative PCR as an alternative to Southern blot or fluorescence in situ hybridization for detection of gene copy number changes.
Jasmien Hoebeeck
Franki Speleman
Jo Vandesompele
Bookchapter
in
Methods in Molecular Biology
2007
Report of a female patient with mental retardation and tall stature due to a chromosomal rearrangement disrupting the OPHN1 gene on Xq12
Björn Menten
Karen Buysse
Stefan Vermeulen
Jo Vandesompele
Geert Mortier
Franki Speleman
A1
Journal Article
in
EUROPEAN JOURNAL OF MEDICAL GENETICS
2007
Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2007
qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data
Jan Hellemans
Geert Mortier
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
GENOME BIOLOGY
2007
2006
Comprehensive NF1 screening on cultured Schwann cells from neurofibromas: towards an extensive study of the somatic mutation spectrum in neurofibromatosis type 1
Ophélia Maertens
Jo Vandesompele
Sofie De Schepper
Anne De Paepe
Geert Mortier
Sandra Janssens
Franki Speleman
A1
Journal Article
in
Human Mutation
2006
Development of a new set of reference genes for normalization of real-time RT-PCR data of porcine backfat and Longissimus dorsi muscle, and evaluation with PPARGC1A
Tim Erkens
Mario Van Poucke
Jo Vandesompele
Karen Goossens
Alex Van Zeveren
Luc Peelman
A1
Journal Article
in
BMC BIOTECHNOLOGY
2006
Differential prion protein mRNA expression in sheep blood
Mario Van Poucke
Jo Vandesompele
Adelheid De Ketelaere
Karen Goossens
Marc Mattheeuws
Alex Van Zeveren
Luc Peelman
C3
Conference
2006
EVII is consistently expressed as principal transcript in common and rare recurrent 3q26 rearrangements
Bruce Poppe
Jo Vandesompele
Barbara Cauwelier
Nurten Yigit
Anne De Paepe
Franki Speleman
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2006
Emerging patterns of cryptic chromosomal imbalance in patients with idiopathic mental retardation and multiple congenital anomalies: a new series of 140 patients and review of published reports
Björn Menten
Karen Buysse
Jo Vandesompele
Sandra Janssens
Anne De Paepe
Geert Mortier
Franki Speleman
A1
Journal Article
in
JOURNAL OF MEDICAL GENETICS
2006
Expression profiling suggests underexpression of the GABA(A) receptor subunit delta in the fragile X knockout mouse model
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
NEUROBIOLOGY OF DISEASE
2006
Genome wide measurement of DNA copy number changes in neuroblastoma: dissecting amplicons and mapping losses, gains and breakpoints
Evi Michels
Jo Vandesompele
Jasmien Hoebeeck
Björn Menten
Katleen De Preter
Genevieve Laureys
Nadine Van Roy
Franki Speleman
A1
Journal Article
in
CYTOGENETIC AND GENOME RESEARCH
2006
High throughput analyses for assessment of DNA copy number and methylation status for chromosome 3p genes in high-risk neuroblastoma
Jasmien Hoebeeck
Franki Speleman
Jo Vandesompele
Dissertation
2006
Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes
Katleen De Preter
Jo Vandesompele
Nurten Yigit
Yves Benoit
Anne De Paepe
Genevieve Laureys
Franki Speleman
A1
Journal Article
in
GENOME BIOLOGY
2006
Identification of MYCN transcriptional target genes in neuroblastoma
Filip Pattyn
Franki Speleman
Jo Vandesompele
Dissertation
2006
MethBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Filip Pattyn
Jasmien Hoebeeck
Piet Robbrecht
Evi Michels
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
BMC BIOINFORMATICS
2006
Murine m cells express annexin V specifically
Phebe Verbrugghe
Wim Waelput
Birger Dieriks
Anouk Waeytens
Jo Vandesompele
Claude Cuvelier
A1
Journal Article
in
JOURNAL OF PATHOLOGY
2006
PPARGC1A mRNA expression in backfat and longissimus dorsi muscle in the pig
Tim Erkens
Mario Van Poucke
Jo Vandesompele
Karen Goossens
Alex Van Zeveren
Luc Peelman
C3
Conference
2006
PRNP polymorphisms in sheep with differential PRNP mRNA expression in blood
Mario Van Poucke
Jo Vandesompele
Adelheid De Ketelaere
Karen Goossens
Alex Van Zeveren
Luc Peelman
C1
Conference
2006
Potential application of ELAVL4 real-time quantitative reverse transcription-PCR for detection of disseminated neuroblastoma cells
Katrien Swerts
Barbara De Moerloose
Catharina Dhooge
Jo Vandesompele
Yves Benoit
Genevieve Laureys
Jan Philippé
A1
Journal Article
in
CLINICAL CHEMISTRY
2006
RTPrimerDB : the real-time PCR primer and probe database, major update 2006
Filip Pattyn
Piet Robbrecht
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2006
Real-time quantitative allele discrimination assay using 3 ' locked nucleic acid primers for detection of low-percentage mosaic mutations
Ophélia Maertens
Franki Speleman
Jo Vandesompele
Editorial material
2006
Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma
Tom Van Maerken
Franki Speleman
Irina Lambertz
Sarah De Clercq
Els De Smet
Nurten Yigit
Jan Philippé
Anne De Paepe
Jean-Christophe Marine
Jo Vandesompele
A1
Journal Article
in
CANCER RESEARCH
2006
The potential (radio-)biological impact of launch vibration
Jo Vandesompele
Sofie De Schynkel
Patric Van Oostveldt
A1
Journal Article
in
ACTA ASTRONAUTICA
2006
The von Hippel-Lindau tumor suppressor gene expression level has prognostic value in neuroblastoma
Jasmien Hoebeeck
Jo Vandesompele
Katleen De Preter
Nadine Van Roy
Els De Smet
Nurten Yigit
Anne De Paepe
Genevieve Laureys
Franki Speleman
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2006
Translocation-excision-deletion-amplification mechanism leading to nonsyntenic coamplification of MYC and ATBF1
Nadine Van Roy
Jo Vandesompele
Björn Menten
Els De Smet
Anne De Paepe
Franki Speleman
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2006
2005
A dual fluorescent multiprobe assay for prion protein genotyping in sheep
Mario Van Poucke
Jo Vandesompele
Marc Mattheeuws
Alex Van Zeveren
Luc Peelman
A1
Journal Article
in
BMC INFECTIOUS DISEASES
2005
A dual fluorescent multiprobe assay for prion protein genotyping in sheep
Mario Van Poucke
Jo Vandesompele
Marc Mattheeuws
Alex Van Zeveren
Luc Peelman
C3
Conference
2005
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias
Franki Speleman
Barbara Cauwelier
Bruno Verhasselt
Bruce Poppe
Nadine Van Roy
Jo Vandesompele
Barbara De Moerloose
Yves Benoit
Anne De Paepe
A1
Journal Article
in
LEUKEMIA
2005
Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania
Jo Vandesompele
A1
Journal Article
in
PARASITOLOGY
2005
Identification of an unbalanced X-autosome translocation by array CGH in a boy with a syndromic form of chondrodysplasia punctata brachytelephalangic type
Björn Menten
Karen Buysse
Jo Vandesompele
Els De Smet
Anne De Paepe
Franki Speleman
Geert Mortier
A1
Journal Article
in
EUROPEAN JOURNAL OF MEDICAL GENETICS
2005
Impact of RNA quality on reference gene expression stability
Claudina Perez Novo
Cindy Claeys
Franki Speleman
Paul Van Cauwenberge
Claus Bachert
Jo Vandesompele
A1
Journal Article
in
BIOTECHNIQUES
2005
No evidence for correlation of DDX1 gene amplification with improved survival probability in patients with MYCN-amplified neuroblastomas
Katleen De Preter
Franki Speleman
Anne De Paepe
Nadine Van Roy
Genevieve Laureys
Jo Vandesompele
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2005
Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11
Katleen De Preter
Jo Vandesompele
Björn Menten
Nurten Yigit
Wim Waelput
Nadine Van Roy
Franki Speleman
A1
Journal Article
in
BMC GENOMICS
2005
Rapid detection of VHL exon deletions using real-time quantitative PCR
Jasmien Hoebeeck
Bruce Poppe
Els De Smet
Nurten Yigit
Kathleen Claes
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
LABORATORY INVESTIGATION
2005
Selection of reference genes for quantitative real-time PCR in bovine preimplantation embryos
Karen Goossens
Mario Van Poucke
Ann Van Soom
Jo Vandesompele
Alex Van Zeveren
Luc Peelman
A1
Journal Article
in
BMC DEVELOPMENTAL BIOLOGY
2005
Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma
Jo Vandesompele
Katleen De Preter
Nadine Van Roy
Sylvia De Bie
Anne De Paepe
Genevieve Laureys
Franki Speleman
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2005
arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays
Björn Menten
Filip Pattyn
Katleen De Preter
Piet Robbrecht
Evi Michels
Karen Buysse
Geert Mortier
Anne De Paepe
Stefan Vermeulen
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
BMC BIOINFORMATICS
2005
2004
Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons
Katleen De Preter
Filip Pattyn
Geert Berx
Kristin Strumane
Björn Menten
Frans Van Roy
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
BMC GENOMICS
2004
Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies
Bruce Poppe
Jo Vandesompele
Nurten Yigit
Anne De Paepe
Franki Speleman
A1
Journal Article
in
BLOOD
2004
Gene-expression profiling reveals distinct expression patterns for classic versus variant Merkel cell phenotypes and new classifier genes to distinguish Merkel cell from small-cell lung carcinoma
Jo Vandesompele
Tom Boonefaes
Pieter Rottiers
Nadine Van Roy
Anne De Paepe
Franki Speleman
A1
Journal Article
in
ONCOGENE
2004
Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis
Jan Hellemans
Andy Willaert
Björn Menten
Nadine Van Roy
Stefan Vermeulen
Anne De Paepe
Jean Naeyaert
Jo Vandesompele
Franki Speleman
Paul Coucke
Geert Mortier
A1
Journal Article
in
NATURE GENETICS
2004
Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation
Jo Vandesompele
Filip Pattyn
Franki Speleman
A1
Journal Article
in
LABORATORY INVESTIGATION
2004
No evidence for involvement of SDHD in neuroblastoma pathogenesis
Katleen De Preter
Jo Vandesompele
Jasmien Hoebeeck
Joél Smet
Genevieve Laureys
Nadine Van Roy
Frank Roels
Rudy Van Coster
Marleen Praet
Anne De Paepe
Franki Speleman
A1
Journal Article
in
BMC CANCER
2004
The human FOXL2 mutation database
Diane Beysen
Jo Vandesompele
Anne De Paepe
Elfride De Baere
A1
Journal Article
in
HUMAN MUTATION
2004
2003
Application of laser capture microdissection in genetic analysis of neuroblastoma and neuroblastoma precursor cells
Katleen De Preter
Jo Vandesompele
Mireille Van Gele
Jasmien Hoebeeck
Els De Smet
Genevieve Laureys
Nadine Van Roy
Anne De Paepe
Franki Speleman
A1
Journal Article
in
CANCER LETTERS
2003
Evidence for involvement of a tumor suppressor gene on 1p in malignant peripheral nerve sheath tumors
Nadine Van Roy
Jo Vandesompele
Ludwine Messiaen
Simon Van Belle
Anne De Paepe
Franki Speleman
A1
Journal Article
in
CANCER GENETICS AND CYTOGENETICS
2003
Expression profiling reveals involvement of the GABA(A) receptor subunit delta in the fragile X syndrome
Jo Vandesompele
Franki Speleman
C3
Conference
2003
ID2 expression in neuroblastoma does not correlate to MYCN levels and lacks prognostic value
Jo Vandesompele
Katleen De Preter
Franki Speleman
A1
Journal Article
in
ONCOGENE
2003
More than 125 FOXL2 mutations and variants in BPES and POF patients in the human FOXL2 allelic variant database
Diane Beysen
Jo Vandesompele
Filip Pattyn
Anne De Paepe
Ludwine Messiaen
Elfride De Baere
C3
Conference
2003
Quantitative real time polymerase chain reaction for measurement of human interleukin-5 receptor alpha spliced isoforms mRNA
Claudina Perez Novo
Jo Vandesompele
Gabriële Holtappels
Franki Speleman
Philippe Gevaert
Paul Van Cauwenberge
Claus Bachert
A1
Journal Article
in
BMC BIOTECHNOLOGY
2003
RTPrimerDB : the Real-Time PCR primer and probe database
Filip Pattyn
Franki Speleman
Anne De Paepe
Jo Vandesompele
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2003
Regulation of peroxisomal genes by DHEA and vitamin D
Jo Vandesompele
Franki Speleman
Frank Roels
A1
Journal Article
in
PEROXISOMAL DISORDERS AND REGULATION OF GENES
2003
2002
A brief commentary on "Chromosomal aberrations in neuroblastoma cell lines identified by cross species color banding and chromosome painting".
Jo Vandesompele
Franki Speleman
A1
Journal Article
in
CANCER GENETICS AND CYTOGENETICS
2002
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
Jo Vandesompele
Katleen De Preter
Filip Pattyn
Bruce Poppe
Nadine Van Roy
Anne De Paepe
Franki Speleman
A1
Journal Article
in
GENOME BIOLOGY
2002
Delineation of the heterogeneous pattern of genomic changes and identifacation of differentially expressed genes in neuroblastoma
Jo Vandesompele
Dissertation
2002
Elimination of primer-dimer artifacts and genomic coamplification using a two-step SYBR green I real time RT-PCR.
Jo Vandesompele
Anne De Paepe
Franki Speleman
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
2002
Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type I patients.
Nadine Van Roy
Jo Vandesompele
Geert Berx
Mireille Van Gele
Els De Smet
Anne De Paepe
Genevieve Laureys
Frans Van Roy
Franki Speleman
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2002
Modulation of the peroxisomal gene expression pattern by dehydroepiandrosterone and vitamin D : therapeutic implications
Marianne Depreter
Jo Vandesompele
Marc Espeel
Franki Speleman
Frank Roels
A1
Journal Article
in
JOURNAL OF ENDOCRINOLOGY
2002
Pathological splice mutations outside the invariant AG/GT splice sites of BRCA1 exon 5 increase alternative transcript levels in the 5 ' end of the BRCA1 gene.
Kathleen Claes
Jo Vandesompele
Bruce Poppe
Anne De Paepe
Ludwine Messiaen
A1
Journal Article
in
ONCOGENE
2002
Quantification of MYCN, DDX1, and NAG gene copy number in neuroblastoma using a real-time quantitative PCR assay.
Katleen De Preter
Franki Speleman
Genevieve Laureys
Anne De Paepe
Nadine Van Roy
Jo Vandesompele
A1
Journal Article
in
MODERN PATHOLOGY
2002
Quantification of NF1 transcripts reveals novel highly expressed splice variants.
Ina Vandenbroucke
Jo Vandesompele
Anne De Paepe
Ludwine Messiaen
A1
Journal Article
in
FEBS LETTERS
2002
Quantification of soluble and membrane anchored isoforms of IL-5R alpha using real-time PCR
Jo Vandesompele
Philippe Gevaert
Paul Van Cauwenberge
Claus Bachert
C3
Conference
2002
2001
Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in neuroblastoma cell lines.
Nadine Van Roy
Heidi Van Limbergen
Jo Vandesompele
Mireille Van Gele
Bruce Poppe
Genevieve Laureys
Anne De Paepe
Franki Speleman
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2001
Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11Q deletion in tumors lacking MYCN amplification.
Jo Vandesompele
Nadine Van Roy
Genevieve Laureys
Franki Speleman
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
2001
Multicentre analysis of patterns of DNA gains and losses in 204 neuroblastoma tumors: How many genetic subgroups are there?
Jo Vandesompele
Franki Speleman
Nadine Van Roy
Genevieve Laureys
A1
Journal Article
in
MEDICAL AND PEDIATRIC ONCOLOGY
2001
2000
Chromosome 2 short arm translocations revealed by M-FISH analysis of neuroblastoma cell lines.
Nadine Van Roy
Heidi Van Limbergen
Jo Vandesompele
Mireille Van Gele
Bruce Poppe
Genevieve Laureys
Anne De Paepe
Franki Speleman
A1
Journal Article
in
MEDICAL AND PEDIATRIC ONCOLOGY
2000
Structure and mutation analysis of the gene encoding DNA fragmentation factor 40 (caspase-activated nuclease), a candidate neuroblastoma tumour suppressor gene.
Nadine Van Roy
Jo Vandesompele
Mireille Van Gele
Franki Speleman
A1
Journal Article
in
HUMAN GENETICS
2000
1999
Neuroblastoma: from molecular cytogenetics to gene expression profiling
Jo Vandesompele
Nadine Van Roy
Geert Berx
Anne De Paepe
Genevieve Laureys
Frans Van Roy
Franki Speleman
C3
Conference
1999
1998
Characteristic pattern of chromosomal gains and losses in Merkel cell carcinoma detected by comparative genomic hybridization
Mireille Van Gele
Franki Speleman
Jo Vandesompele
Nadine Van Roy
A1
Journal Article
in
CANCER RESEARCH
1998
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.
Jo Vandesompele
Nadine Van Roy
Mireille Van Gele
Genevieve Laureys
Anne De Paepe
Franki Speleman
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
1998
Molecular analysis of lp36 breakpoints in two Merkel cell carcinomas.
Mireille Van Gele
Nadine Van Roy
Ludwine Messiaen
Jo Vandesompele
Marie Geerts
Franki Speleman
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
1998
Quantification of splice variants using real-time PCR. Nucleic Acids Res., 29, 2001, E68.
Ina Vandenbroucke
Jo Vandesompele
Anne De Paepe
Ludwine Messiaen
A2
Journal Article