Project

The role of miRNAs during bovine preimplantation development

Code
3G059310
Duration
01 January 2010 → 31 December 2015
Funding
Research Foundation - Flanders (FWO)
Promotor
Research disciplines
  • Natural sciences
    • Animal biology
    • Genetics
  • Medical and health sciences
    • Laboratory medicine
    • Medical systems biology
    • Physiology
    • Laboratory medicine
    • Medical systems biology
    • Molecular and cell biology
    • Physiology
    • Laboratory medicine
    • Medical systems biology
    • Molecular and cell biology
    • Physiology
  • Agricultural and food sciences
    • Veterinary medicine
Keywords
gene expression bovine embryo miRNA epigenetics
 
Project description

Although much improved, in vitro produced embryo's are still of inferior quality compared to in vivo embryo's. This is visible in a dysregulation of embryonic gene expression, leading to problems during foetal and postnatal development. Studies of regulation of embryonic gene expression have suggested that, next to transcription factors, epigenetic motifications and microRNA's are important regulators of gene expression