Project

Interrelationship of pulmonary inflammation, systemic inflammation and airway remodelling in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD).

Code
3G019509
Duration
01 January 2009 → 31 December 2014
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Physiology
    • Respiratory medicine
    • Immunology
    • Laboratory medicine
    • Physiology
    • Respiratory medicine
    • Immunology
    • Laboratory medicine
    • Physiology
    • Respiratory medicine
Keywords
inflammation remodelling COPD cigarette smoke
 
Project description

The overall aim of this coordinated, multidisciplinary research proposal is to elucidate the interrelationship between systemic inflammation, pulmonary inflammation and airway remodelling in the pathogenesis of COPD. The central hypothesis is that "COPD ensues from an inappropriate (ie exaggerated, harmful) inflammatory and/or fibrogenic response of the host to cigarette smoke".