A new fragment-centric perspective on proteomics

Cofunding core facility - ProGenTomics

Cell-based non-invasive prenatal testing: circulating trophoblast enrichment and genetic analysis.

Collaborative science: from proteomics method development to core facility.

Cracking the Histone Code: Mass Spectrometry-Based Insights into Epigenetic Regulation in Cancer.

Doctoral project Ann-Sophie Vander Plaetsen

Doctoral project Bart Broeckx

Doctoral project Christophe Van Neste

Doctoral project Elisabeth Govaert

Doctoral project Ellen Scheerlinck

Doctoral project Franck Limonier

Doctoral project Laura De Clerck

Doctoral project Laura Van Hoyweghen

Doctoral project Liesbeth Vossaert

Doctoral project Marie-Alice Fraiture

Doctoral project Marjolein D'Hollander

Doctoral project Nicky Van Thuyne

Doctoral project Nicolas Scarcez

Doctoral project Paulien Meert

Doctoral project Pieter Glibert

Doctoral project Sander Willems

Doctoral project Sandra Soetaert

Doctoral project Senne Cornelis

Doctoral project Shahid Hussain

Doctoral project Trees Lepez

Doctoral project Veerle Gobin

ENSURED - New open strategy for impurity surveillance of commercial microbial fermentation food products: food supplements and vitamins as proof of concept

EPIC PROTEOMICS: AN MS-BASED WORKFLOW FOR PARALLEL PROFILING OF HISTONE EPIGENETICS AND PROTEIN EXPRESSION

Genomic approaches to characterize food and feed mixtures : engineered plants and species identification as study case

Integrative Transcriptomic and Epigenomic Analysis: Unraveling Mechanisms in Fertility Restoration and Oocyte Interventions

Mass spectrometry based forensic proteomics brings light to the crime scene

Migration, nutrition and health of the first permanent residents of Belgium: inter- and multidisciplinary perspectives. (BOF22/GOA/008)

Mobile pandemic preparedness: a mass spectrometric contribution

Single-cell profiling of the histone code and proteome to unravel drug resistance mechanisms in Acute Myeloid Leukemia.

Strategies to control the presence of microbial impurities, including genetically modified microorganisms, in food enzymes.

The wonderful world of histones and stem cells: a fairy tale written by mass spectrometry.

Tools for bridging discovery proteomics and pandemic preparedness.

A sequencing-centric future for enhanced healthcare: Refining patient genotyping in personalized medicine and accelerating monoclonal antibody development.

Bringing science to the scene: Novel strategies for portable forensic DNA profiling.

Development, evaluation and optimization of next generation sequencing data analysis tools in support of a fast response for public health and food chain safety

Doctoral project Amir Jahanshahi

Doctoral project Galbha Duggal

Doctoral project Jitesh Neupane

Doctoral project Maaike Catteeuw

Doctoral project Senne Cornelis

Doctoral project Vanessa Verbeke

Empirical exploration of novel DNA probes for hybridization to tandem repeats

Exploring and optimizing of variant detection and phasing methods in pharmacogenomics.

Farmacogenomics

Improved haplotyping and pharmacogenetic prediction with nanopore Cas9-targeted sequencing

Isothermal STR Analysis Using Recombinase Polymerase Amplification with Probe-Based Genotyping for Microfluidic Chip Integration

Nanopore sequencing of complete pharmacogenes

RNA-Seq and Bioinformatics Methods for Studying Embryo Development and Quality in Bovine and Equine Species: Challenges and Opportunities.

Unraveling the Immunological Tolerance Loss in Vitiligo and Alopecia Areata: Exploring Antigen Specificities for Potential Immunotherapy

A Belgian representation on the Scientific Advice Working Party (SAWP) of the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA).

Accurate peptide/protein quantification as a quality control and normalization template for biological proteome samples prior to LC-MS/MS using the Big Lunatic microfluidic UV/vis system.

Addressing the need for increased analytical capacity for biopharmaceuticals and forensic toxicology through automated sample preparation.

A role for the T lymphocyte in the production of antibodies against citrullinated proteins in Rheumatoid Arthritis

Artemisinin biosynthesis in Artemisia annua trichomes

A way out of the reagents shortages: an MS-based diagnostic test focused on corona protein detection

Bioinformatics: from nucleotids to networks (N2N)

Citrullination of vimentin in rheumatoid arthritis: balancing on the border between proliferation and apoptosis.

Cofunding core facility - UGent NGS Core

Data Independent Acquisition Mass Spectrometry to Mine Human Stem Cell Histone Epigenetics

Data Independent Acquisition Mass Spectrometry to Mine Human Stem Cell Histone Epigenetics

Detection and phenotyping microchimerie of fetal cells in autoimmune pathologies

Epic Proteomics: an MS-based workflow for parallel profiling of histone epigenetics and protein expression.

Ex ovo omnia: from stem cell to oocyte

Extending the forensic toolbox: the use of Data-Independent Mass Spectrometry for forensic peptide marker discovery and MRM assay development.

Farmacoproteomics and genomics towards personalized medicines

High throughput MS-based histone PTM screening: Filling a void in pharmacoepigenetics.

Histone epigenetic profiling in pharmaco- and toxicoepigenetics.

Identification and functional analysis of signaling molecules with a possible function in pluripotency and differentiation of embryonic stem cells

Identification of T cell antigenic peptides in MHC complexes on Chronic Lymphocytic Leukemia B cells

Ion mobility assisted Data Independent Acquisition of the histone code: opening up peptide-centric data mining.

IsoFlux System: Isolation of rare cells from biological samples

Looking for causal genetic variation in candidate genes for hip dysplasia in dogs

Pandemic preparedness: developing a multiplexed mass spectrometry assay to screen for pathogens and the induced immune response.

Pathways to pluripotency and differentiation in embryos and embryonic stem cells

"PeTRAQ" as a model for the development of a new MS-based technique for the elucidation of post-translational modifications

Pharmacoepigenetics: towards personalized epidrug treatment

Proteolytical histone processing during human stem cell differentiation

Proteomics Expertise Center Ugent

Qualitative and quantitative analysis of the antigenic epitopes of citrullinatend vimentin in rheumatoid arthritis

Research equipment: Ion Personal Genome Machine TM (PGM TM) Sequencer en Ion Proton TM Sequencer

Restoring fertility by the 3R-approach : rejuvenating, replacing or reconstructing the oocyte

Scientific collaboration between UGent and FAGG 2021-2023 for membership SAWP EMA

Scientific cooperation between Ghent and FAGG

Scientific cooperation UGent - FAMHP - 2015

Sequencing Expertise Centre (Life Sciences)

STaR-chip, the ultimate biometric identification check

Towards a first bird's eye view of the histone code using dataindependent acquisition mass spectrometry.

Tracking changes in the histone modification pattern by untargeted mass spectrometry

Trichomes, the key to an increased production of artemisinin in Artemisia annua

Ceation of patient specific stem cells through somatic cell nuclear transfer of induced pluripotent stem cells

Culture-dependent and independent anaysis of biofilm-associated microflora on endotracheal tubes and their role in ventilator-associated pneumonia

Embryo-maternal interaction in the horse.

Empirical exploration of novel DNA probes for hybridization to tandem repeats

Fetal cell isolation and characterization for cell-based non-invasive prenatal genetic diagnosis

Gene discovery in the metabolic pathways of Ecuadorian Quinoa (chenopodium quinoa)

Isothermal STR Analysis Using Recombinase Polymerase Amplification with Probe-Based Genotyping for Microfluidic Chip Integration

Lab-on-a-Chip (LoC) for forensic STR profiling.

Nanopore sequencing of complete pharmacogenes after CRISPR/Cas9 enrichment in tamoxifen and clopidogrel patients allowing enhanced haplotyping and continuous scale machine learning efficacy prediction.

Research on new analytical challenges for mycotoxin detection: Masked mycotoxins.

Research towards the molecular pathogenesis of chlamydophila psittaci in human macrophages and epithelial cells: genomics, proteomics and methylomics of highly and less virulent strains.

The development of a specific monoclonal antibody against deoxynivalenol

The role of mitogen-activated protein kinases (MAPK) and their downstream effectoren in transient stress resistance in in vitro produced bovine embryos

the SEGa project: The Science and Ethics of stem cell-derived Gametes

An integrated metabolomics approach to unravel the pathophysiology of early feline chronic kidney disease.

Characterisation of an obese piglet model to study drug dosing in obese children

Migration, diet and health of the first permanent settlers of Belgium: inter- and multi-disciplinary perspectives