Project

Fetal cell isolation and characterization for cell-based non-invasive prenatal genetic diagnosis

Duration
01 October 2017 → 30 September 2021
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Genetics
    • Systems biology
  • Medical and health sciences
    • Diagnostics
    • Laboratory medicine
    • Molecular and cell biology
    • Morphological sciences
    • Oncology
    • Diagnostics
    • Laboratory medicine
    • Morphological sciences
    • Oncology
    • Medicinal products
    • Diagnostics
    • Laboratory medicine
    • Molecular and cell biology
    • Morphological sciences
    • Oncology
Keywords
rare cell isolation from blood Cell-based non-invasive prenatal diagnosis (NIPT) liquid biopsy massively parallel sequencing
 
Project description

Size-exclusion micro-fluidic technology will be developped to capture fetal trophoblasts from maternal peripheral blood, allowing downstream massively parallel sequencing analyses. These methods can be used to develop non-invasive prenatal testing (NIPT) providing diagnoses that can currently only be obtained by invasive techniques.