Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Researcher

Dieter Deforce

Awards & Distinctions

584 Results

2024

An in-depth investigation of the microbiota and its virulence factors associated with severe udder cleft dermatitis lesions

Anne-Sofie VermeerschM. AliYannick GansemansFilip Van NieuwerburghRichard DucatellePeter GeldhofDieter DeforceJ. CallensGeert Opsomer

A1 Journal Article in JOURNAL OF DAIRY SCIENCE

Baselining physiological parameters in three muscles across three equine breeds : what can we learn from the horse?

Carmen Vidal Moreno de VegaConstance De meeûsBerit BoshuizenLorie De MaréYannick GansemansFilip Van NieuwerburghDieter DeforceKlara GoethalsWard De SpiegelaereLuc Leybaert et al.

A1 Journal Article in FRONTIERS IN PHYSIOLOGY

Contribution of combined stressors on density and gene expression dynamics of the copepod Temora longicornis in the North Sea

Ilias SemmouriKarel De SchamphelaereFilip Van NieuwerburghDieter DeforceColin JanssenJana Asselman

A1 Journal Article in MOLECULAR ECOLOGY

Epigenetics in personalized toxicity

Laura CorveleynSigrid VerhelstDieter DeforceMaarten Dhaenens

Bookchapter in Personalized epigenetics : a volume in translational epigenetics

Expression profile and gap-junctional transfer of microRNAs in the bovine cumulus-oocyte complex

Rani SixCamilla BenedettiYuan FanGuan XueFengYannick GansemansMohamed HediaOsvaldo Américo Bogado PascottiniKrishna PavaniFilip Van NieuwerburghDieter Deforce et al.

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Genome-wide methylome stability and parental effects in the worldwide distributed Lombardy poplar

An Vanden BroeckTim MeesePieter VerscheldeKaren CoxBerthold HeinzeDieter DeforceEllen De MeesterFilip Van Nieuwerburgh

A1 Journal Article in BMC BIOLOGY

MicroRNA-146b negatively affects bovine embryo development and quality

Krishna PavaniGuan XueFengJayendra ChunduruTim MeeseLuc PeelmanFilip Van NieuwerburghDieter DeforceAn HendrixKelly TillemanAnn Van Soom et al.

A1 Journal Article in REPRODUCTION

Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T-cell lymphoblastic leukemia

André Pedro Pinto De AlmeidaSara T'SasLuca PagliaroIgor FijalkowskiWouter SleeckxHannah Van SteenbergeRaffaella ZamponiBéatrice LintermansWouter Van LoockeBruno Palhais et al.

A1 Journal Article in HEMASPHERE

Proteomics data in vitiligo : a scoping review

Danique BerrevoetFilip Van NieuwerburghDieter DeforceReinhart Speeckaert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

The promise of omics approaches for pediatric drug development

Sigrid VerhelstTess GoessensRoger Peró GascónMarthe De BoevreFrancis ImpensDieter DeforceMaarten Dhaenens

Bookchapter in Essentials of translational pediatric drug development : from past needs to future oportunities

2023

Baselining physiological parameters in posture versus locomotion muscles across breeds towards tailored dietary and training management

Carmen Vidal Moreno de VegaConstance De meeûsBerit BoshuizenLorie De MaréYannick GansemansFilip Van NieuwerburghDieter DeforceKlara GoethalsWard De SpiegelaereElisabeth Verdegaal et al.

Cathepsin-L secreted by high-quality bovine embryos exerts an embryotrophic effect in vitro

Annelies RaesEline WydoogheKrishna PavaniOsvaldo Américo Bogado PascottiniKatleen Van SteendamMaarten DhaenensAnnekatrien BoelSonia HerasBjörn HeindryckxLuc Peelman et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comparative transcriptomics of porcine liver-resident CD8αdim, liver CD8αhigh and circulating blood CD8αhigh NK cells reveals an intermediate phenotype of liver CD8αhigh NK cells

Leen HermansSofie DenaeghelRobert J. J. JansensSteffi De PelsmaekerFilip Van NieuwerburghDieter DeforceEverardo Hegewisch-SolloaEmily M. MaceEric CoxBert Devriendt et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Dynamic of training and acute exercised-induced shifts in muscular glucose transporter (GLUT) 4, 8 and 12 expression in locomotion versus posture muscles in healthy horses.

Carmen Vidal Moreno de VegaDiete LemmensConstance De meeûsBerit BoshuizenLorie De MaréLuc LeybaertKlara GoethalsJean Eduardo de OliveiraGuilherme HosotaniDieter Deforce et al.

Dynamics of training and acute exercise-induced shifts in muscular glucose transporter (GLUT) 4, 8, and 12 expression in locomotion versus posture muscles in healthy horses

Carmen Vidal Moreno de VegaDiete LemmensConstance de Meeus d'ArgenteuilBerit BoshuizenLorie De MaréLuc LeybaertKlara GoethalsJean Eduardo de OliveiraGuilherme HosotaniDieter Deforce et al.

A1 Journal Article in FRONTIERS IN PHYSIOLOGY

Effect of aleurone on glucose & insuline dynamics and gut microbiome of trained horses

Berit BoshuizenLorie De MaréConstance De meeûsLindsey DevisscherCarmen Vidal Moreno de VegaJean Eduardo de OliveireGuilherme HosotaniYannick GansemansTim MeeseFilip Van Nieuwerburgh et al.

How do engineered Yarrowia lipolytica strains secrete free fatty acids : hints from comparative transcriptomics

José Manuel Salvador LópezLea VidalMichelle PatriciaFilip Van NieuwerburghDieter DeforceJean-Marc NicaudInge Van Bogaert

A1 Journal Article in FEMS YEAST RESEARCH

Micro‐topographies induce epigenetic reprogramming and quiescence in human mesenchymal stem cells

Steven VermeulenBart Van PuyveldeLaura Bengtsson del BarrioRuben AlmeyBernard K. van der VeerDieter DeforceMaarten DhaenensJan de Boer

A1 Journal Article in ADVANCED SCIENCE

Molecular analysis of broad-spectrum induced resistance in rice by the green leaf volatile Z-3-hexenyl acetate

Willem DesmedtMaarten AmeyeOsvaldo FilipeEvelien De WaeleFilip Van NieuwerburghDieter DeforceLieven Van MeulebroekLynn VanhaeckeTina KyndtMonica Höfte et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD

Hannelore Van EeckhoutteChantal DonovanRichard Y. KimThomas M. ConlonMeshal AnsariHaroon KhanRanjith JayaramanNicole G. HansbroYves DondelingerTom Delanghe et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

RNA-seq and bioinformatics methods for studying embryo development and quality in bovine and equine species : challenges and opportunities

Tim MeeseFilip Van NieuwerburghDieter DeforceKrishna Pavani

Severe udder cleft dermatitis lesion transcriptomics points to an impaired skin barrier, defective wound repair and a dysregulated inflammatory response as key elements in the pathogenesis

Anne-Sofie VermeerschMohsin AliYannick GansemansFilip Van NieuwerburghPeter GeldhofRichard DucatelleDieter DeforceJozefien CallensGeert Opsomer

A1 Journal Article in PLOS ONE

Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies' adaptive sampling

Koen DeserrannoLaurentijn TillemanKaat RubbenDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

The wonderful world of histones and stem cells : a fairy tale written by mass spectrometry

Sigrid VerhelstDieter DeforceMaarten Dhaenens

2022

A comprehensive LFQ benchmark dataset on modern day acquisition strategies in proteomics

Bart Van PuyveldeSimon DaledSander WillemsRalf GabrielsAnne Gonzalez de PeredoKarima ChaouiEmmanuelle Mouton-BarbosaDavid BouyssiéKurt BoonenChristopher J. Hughes et al.

A1 Journal Article in SCIENTIFIC DATA

A large scale mass spectrometry-based histone screening for assessing epigenetic developmental toxicity

Sigrid VerhelstBart Van PuyveldeSander WillemsSimon DaledSenne CornelisLaura CorveleynEwoud WillemsDieter DeforceLaura De ClerckMaarten Dhaenens

A1 Journal Article in SCIENTIFIC REPORTS

An interactive mass spectrometry atlas of histone posttranslational modifications in T-cell acute leukemia

Lien ProvezBart Van PuyveldeLaura CorveleynNina DemeulemeesterSigrid VerhelstBeatrice LintermansSimon DaledJuliette RoelsLieven ClementLennart Martens et al.

A1 Journal Article in SCIENTIFIC DATA

Analyzing data independent acquisition mass spectrometry with noiseless ion-networks

Sander WillemsSimon DaledBart Van PuyveldeLaura De ClerckSofie Vande CasteeleFilip Van NieuwerburghDieter DeforceMaarten Dhaenens

Bringing science to the scene : novel strategies for portable DNA profiling

Olivier TytgatFilip Van NieuwerburghDieter DeforceMaarten Fauvart

Cas9 targeted nanopore sequencing with enhanced variant calling improves CYP2D6-CYP2D7 hybrid allele genotyping

Kaat RubbenLaurentijn TillemanKoen DeserrannoOlivier TytgatDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in PLOS GENETICS

Collaborative science : from proteomics method development to core facility

Simon DaledDieter DeforceMaarten Dhaenens

Continuous activation of the IL-17F driven inflammatory pathway in acute and chronic digital dermatitis lesions in dairy cattle

Anne-Sofie VermeerschPeter GeldhofRichard DucatelleYannick GansemansFilip Van NieuwerburghDieter DeforceGeert Opsomer

A1 Journal Article in SCIENTIFIC REPORTS

Cov²MS : an automated and quantitative matrix-independent assay for mass spectrometric measurement of SARS-CoV-2 nucleocapsid protein

Bart Van PuyveldeKatleen Van UytfangheLaurence Van OudenhoveRalf GabrielsTessa Van RoyenArne MatthysMorteza RazaviRichard YipTerry PearsonNicolas Drouin et al.

A1 Journal Article in ANALYTICAL CHEMISTRY

DNA methylation alterations in fractionally irradiated rats and breast cancer patients receiving radiotherapy

Magy SallamMohamed MysaraMohammed Abderrafi BenotmaneAnne P. G. CrijnsDaan SpoorFilip Van NieuwerburghDieter DeforceSarah BaatoutPieter-Jan GunsAn Aerts et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Detection and identification of authorized and unauthorized GMOs using high-throughput sequencing with the support of a sequence-based GMO database

Assia SaltykovaJulien Van BraekelNina PapazovaMarie-Alice FraitureDieter DeforceKevin VannesteSigrid C. J. De KeersmaeckerNancy H. Roosens

A2 Journal Article in FOOD CHEMISTRY: MOLECULAR SCIENCES

Development, evaluation and optimization of next generation sequencing data analysis tools in support of a fast response for public health and food chain safety

Assia SaltykovaKathleen MarchalDieter DeforceSigrid De KeersmaeckerNancy Roosens

Enrichment of circulating trophoblasts from maternal blood using filtration-based Metacell (R) technology

Jana WeymaereAnn-Sophie Vander PlaetsenYASMINE VAN DEN BRANDENEliska PospisilovaOlivier TytgatDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in PLOS ONE

Exploring and optimizing variant detection and phasing methods in pharmacogenomics

Laurentijn TillemanFilip Van NieuwerburghBjörn HeindryckxDieter Deforce

First monitoring for unauthorized genetically modified bacteria in food enzymes from the food market

Marie DeckersMarc De LooseNina PapazovaDieter DeforceMarie-Alice FraitureNancy H. C. Roosens

A1 Journal Article in FOOD CONTROL

Haplotyping pharmacogenes using TLA combined with Illumina or Nanopore sequencing

Laurentijn TillemanKaat RubbenWim Van CriekingeDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts

Krishna PavaniTim MeeseOsvaldo Américo Bogado PascottiniXueFeng GuanXiaoyuan LinLuc PeelmanJoachim HamacherFilip Van NieuwerburghDieter DeforceAnnekatrien Boel et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction

Dick W. ZijlmansIrene TalonSigrid VerhelstAdam BendallKarlien Van NerumAlok JavaliAndrew A. MalcolmSam S. F. A. van KnippenbergLaura BigginsSan Kit To et al.

A1 Journal Article in NATURE CELL BIOLOGY

Metabolism and health effects of rare sugars in a CACO-2/HepG2 coculture model

Amar Daniël Emanuel Van LaarCharlotte GrootaertFilip Van NieuwerburghDieter DeforceTom DesmetKoen BeerensJohn Van Camp

A1 Journal Article in NUTRIENTS

Microbial diversity and antimicrobial susceptibility in endotracheal tube biofilms recovered from mechanically ventilated COVID-19 patients

Frits van CharanteAnneleen WiemePetra RigoleEvelien De CanckLisa OstynLucia GrassiDieter DeforceAurélie CrabbéPeter VandammeMarie Joossens et al.

A2 Journal Article in BIOFILM

Nanopore sequencing of a forensic combined STR and SNP multiplex

Olivier TytgatSonja SkevinDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Profiling the aerobic window of horses in response to training by means of a modified lactate minimum speed test : flatten the curve

Lorie De MaréBerit BoshuizenCarmen Vidal Moreno de VegaConstance De meeûsLukas PlanckeYannick GansemansFilip Van NieuwerburghDieter DeforceJean Eduardo de OliveiraGuilherme Hosotani et al.

A1 Journal Article in FRONTIERS IN PHYSIOLOGY

Proteomic comparison of three wild-type pseudorabies virus strains and the attenuated bartha strain reveals reduced incorporation of several tegument proteins in bartha virions

Jonas DelvaSimon DaledCliff Van WaesbergheRuben AlmeyRobert J. J. JansensDieter DeforceMaarten DhaenensHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

QueSTR probes : Quencher-labeled RNase H2-dependent probes for short tandem repeat genotyping

Olivier TytgatSonja SkevinMaarten FauvartTim StakenborgDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SENSORS AND ACTUATORS B-CHEMICAL

RRM2 enhances MYCN driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Lisa DepestelCarolina de Carvalho NunesLiselot MusIris NelenLouis DelhayeKaylee KellerVolodimir OlexioukFanny De VloedEllen SandersAline Eggermont et al.

Strategies to control the presence of microbial impurities, including genetically modified microorganisms, in food enzymes

Marie DeckersDieter DeforceNancy RoosensMarie-Alice Fraiture

Tools for bridging discovery proteomics and pandemic preparedness

Bart Van PuyveldeDieter DeforceMaarten Dhaenens

Transcriptional dynamics of gametogenesis in the green seaweed Ulva mutabilis identifies an RWP-RK transcription factor linked to reproduction

Xiaojie LiuJonas BlommeKenny BogaertSofie D'hondtThomas WichardDieter DeforceFilip Van NieuwerburghOlivier De Clerck

A1 Journal Article in BMC PLANT BIOLOGY

2021

Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells

Swati MishraJasin TaelmanMina PopovicLaurentijn TillemanEvi DuthooMargot Van der JeughtDieter DeforceFilip Van NieuwerburghBjörn MentenPetra De Sutter et al.

A1 Journal Article in STEM CELLS

An experimental design to extract more information from MS-based histone studies

Laura De ClerckSander WillemsSimon DaledBart Van PuyveldeSigrid VerhelstLaura CorveleynDieter DeforceMaarten Dhaenens

A1 Journal Article in MOLECULAR OMICS

Cell-based non-invasive prenatal testing : circulating trophoblast enrichment and genetic analysis

Jana WeymaereFilip Van NieuwerburghDieter Deforce

Circulating fetal trophoblast enrichment and single cell genetic analysis in the context of cell-based non-invasive prenatal testing

Ann-Sophie Vander PlaetsenFilip Van NieuwerburghDieter Deforce

Cov-MS : a community-based template assay for mass-spectrometry-based protein detection in SARS-CoV-2 patients

Bart Van PuyveldeKatleen Van UytfangheOlivier TytgatLaurence Van OudenhoveRalf GabrielsRobbin BouwmeesterSimon DaledTim Van Den BosschePathmanaban RamasamySigrid Verhelst et al.

A2 Journal Article in JACS AU

Digital polymerase chain reaction for assessment of mutant mitochondrial carry-over after nuclear transfer for In Vitro fertilization

Olivier TytgatMX TangWillem van SnippenbergAnnekatrien BoelRR GuggillaYannick GansemansMichiel Van HerpSofie SymoensWim TrypsteenDieter Deforce et al.

A1 Journal Article in CLINICAL CHEMISTRY

Digital polymerase chain reaction for assessment of mutant mitochondrial carry-over after nuclear transfer for in vitro fertilization

Olivier TytgatMaoxing TangWillem van SnippenbergAnnekatrien BoelRamesh GuggillaYannick GansemansMichiel Van HerpSofie SymoensWim TrypsteenDieter Deforce et al.

A1 Journal Article in CLINICAL CHEMISTRY

Effects of aleurone supplementation on glucose-insulin metabolism and gut microbiome in untrained healthy horses

Berit BoshuizenCarmen Vidal Moreno de VegaLorie De MaréConstance De meeûsJean Eduardo de OliveiraGuilherme HosotaniYannick GansemansDieter DeforceFilip Van NieuwerburghCatherine Delesalle

A1 Journal Article in FRONTIERS IN VETERINARY SCIENCE

Enrichment of circulating trophoblasts from maternal blood using laminar microscale vortices

Ann-Sophie Vander PlaetsenJana WeymaereOlivier TytgatMagali BuyleDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in PRENATAL DIAGNOSIS

Ferroptosis induction in multiple myeloma cells triggers DNA methylation and histone modification changes associated with cellular senescence

Emilie LogieBart Van PuyveldeBart CuypersAnne SchepersHerald BerghmansJelle VerdonckKris LaukensLode GodderisMaarten DhaenensDieter Deforce et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Food Enzyme Database (FEDA) : a web application gathering information about food enzyme preparations available on the European market

Marie DeckersJulien Van BraeckelKevin VannesteDieter DeforceMarie-Alice FraitureNancy H. C. Roosens

A1 Journal Article in DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION

Hepatic cytochrome P450 abundance and activity in the developing and adult Gottingen Minipig : Pivotal data for PBPK modeling

Laura BuyssensLaura De ClerckWim SchelstraeteMaarten DhaenensDieter DeforceMiriam AyusoChris Van GinnekenSteven Van Cruchten

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Histone sample preparation for bottom-up mass spectrometry : a roadmap to informed decisions

Simon DaledSander WillemsBart Van PuyveldeLaura CorveleynSigrid VerhelstLaura De ClerckDieter DeforceMaarten Dhaenens

A2 Journal Article in PROTEOMES

Large scale toxicoepigenetics on histones : a mass spectrometry-based screening assay applied to developmental toxicity

Sigrid VerhelstBart Van PuyveldeSander WillemsSimon DaledSenne CornelisLaura CorveleynEwoud WillemsDieter DeforceLaura De ClerckMaarten Dhaenens

Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensBarbara DepreterYing WuMiriam ErlacherAurélie CayeHélène CavéChristian FlothoValerie de HaasCharlotte M. Niemeyer et al.

A1 Journal Article in SCIENTIFIC REPORTS

MYCN-induced nucleolar stress drives an early senescence-like transcriptional program in hTERT-immortalized RPE cells

Sofia ZanottiSuzanne VanhauwaertChristophe Van NesteVolodimir OlexioukJolien Van LaereMarlies VerschuurenJoni Van der MeulenLiselot MusKaat DurinckLaurentijn Tilleman et al.

A1 Journal Article in SCIENTIFIC REPORTS

Pre-weaning inulin supplementation alters the ileal transcriptome in pigs regarding lipid metabolism

Martine SchroyenBing LiEster Arevalo SuredaYuping ZhangJulie LebloisDieter DeforceFilip Van NieuwerburghJose WavreilleNadia Everaert

A1 Journal Article in VETERINARY SCIENCES

Profiling the aerobic window (AW) of horses in response to training by means of a new LMS (lactate minimum speed) test : flatten the curve

Lorie De MaréBerit BoshuizenCarmen Vidal Moreno de VegaConstance De meeûsLukas PlanckeYannick GansemansFilip Van NieuwerburghDieter DeforceJean de OliveiraCatherine Delesalle

RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia

Filip MatthijssensNitesh D. SharmaMonique NysusChristian K. NicklHuining KangDominique R. PerezBéatrice LintermansWouter Van LoockeJuliette RoelsSofie Peirs et al.

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions

Liselot MusStéphane Van HaverMina PopovicWim TrypsteenSteve LefeverNadja ZeltnerYudelca OgandoEva JacobsGeertrui DeneckerEllen Sanders et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

STRide probes : single-labeled short tandem repeat identification probes

Olivier TytgatMaarten FauvartTim StakenborgDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in BIOSENSORS & BIOELECTRONICS

The CD147 protein complex is involved in entry of Chikungunya virus and related alphaviruses in human cells

Lien De CaluweSandra CoppensKatleen VereeckenSimon DaledMaarten DhaenensXaveer Van OstadeDieter DeforceKevin K. ArienKoen Bartholomeeusen

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

The impact of maternal and piglet low protein diet and their interaction on the porcine liver transcriptome around the time of weaning

Kikianne KroeskeEster Arévalo SuredaJulie UerlingsDieter DeforceFilip Van NieuwerburghMarc HeyndrickxSam MilletNadia EveraertMartine Schroyen

A1 Journal Article in VETERINARY SCIENCES

2020

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

Juliette RoelsMorgan ThénozB SzarzyńskaM LandforsStien De ConinckLisa DemoenLien ProvezAnna KuchmiySteven StrubbeLindy Reunes et al.

A2 Journal Article in BLOOD CANCER DISCOVERY

Break it to make it : from fragmented information to computational coherency in mass spectrometry based proteomics

Sander WillemsDieter DeforceMaarten Dhaenens

Comparative study of preimplantation development following distinct assisted oocyte activation protocols in a PLC-zeta knockout mouse model

Minerva Ferrer BuitragoLaurentijn TillemanVanessa ThysA HachemAnnekatrien BoelFilip Van NieuwerburghDieter DeforceLuc LeybaertPetra De SutterJ. Parrington et al.

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Comprehensive histone epigenetics : a mass spectrometry based screening assay to measure epigenetic toxicity

Sigrid VerhelstLaura De ClerckSander WillemsBart Van PuyveldeSimon DaledDieter DeforceMaarten Dhaenens

A2 Journal Article in METHODSX

Distinct transcriptome signatures of Helicobacter suis and Helicobacter heilmannii strains upon adherence to human gastric epithelial cells

Helena BerlamontChloë De WitteEva BauwensHannah Min JouRichard DucatelleEllen De MeesterYannick GansemansDieter DeforceFilip Van NieuwerburghFreddy Haesebrouck et al.

A1 Journal Article in VETERINARY RESEARCH

Ecological divergence of wild strawberry DNA methylation patterns at distinct spatial scales

Hanne De KortBart PanisDieter DeforceFilip Van NieuwerburghOllivier Honnay

A1 Journal Article in MOLECULAR ECOLOGY

Effect of oral aleurone supplementation on glucose and insulin dynamics of horses in training

Berit BoshuizenConstance De meeûsLorie De MaréCarmen Vidal Moreno de VegaJ De OliveiraYannick GansemansFilip Van NieuwerburghDieter DeforceCatherine Delesalle

First draft genome assembly of the desert locust, Schistocerca gregaria

Heleen VerlindenLieven SterckJia LiZhen LiAnna YsselYannick GansemansRik VerdonckMichiel HoltofHojun SongSpencer T. Behmer et al.

A2 Journal Article in F1000RESEARCH

Germline nuclear transfer in mice may rescue poor embryo development associated with advanced maternal age and early embryo arrest

Maoxing TangMina PopovicPanagiotis StamatiadisMargot Van der JeughtRudy Van CosterDieter DeforcePetra De SutterPaul CouckeBjörn MentenDominic Stoop et al.

A1 Journal Article in HUMAN REPRODUCTION

Kinship analysis on single cells after whole genome amplification

Jana WeymaereAnn-Sophie Vander PlaetsenLaurentijn TillemanOlivier TytgatKaat RubbenSofie GeeraertDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Maternal recognition of pregnancy in the horse : are MicroRNAs the secret messengers?

Katrien SmitsYannick GansemansLaurentijn TillemanFilip Van NieuwerburghMargot Van de VeldeIlse GeritsCyrillus VerversKim RoelsJan GovaereLuc Peelman et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nanopore sequencing of a forensic STR multiplex reveals loci suitable for single-contributor STR profiling

Olivier TytgatYannick GansemansJana WeymaereKaat RubbenDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in GENES

Navigating pluripotency : resetting the primed state and exploring histone modification dynamics in human embryonic stem cells

Jasin TaelmanPetra De SutterDieter Deforce

Pan-cancer pharmacogenetics : targeted sequencing panels or exome sequencing?

Laurentijn TillemanBjörn HeindryckxDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in PHARMACOGENOMICS

RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis

Thomas NaertDionysia DimitrakopoulouDieter TulkensSuzan DemuynckMarjolein CarronRivka NoelandersLiza EeckhoutGert Van IsterdaelDieter DeforceChristian Vanhove et al.

A1 Journal Article in ONCOGENE

Removing the hidden data dependency of DIA with predicted spectral libraries

Bart Van PuyveldeSander WillemsRalf GabrielsSimon DaledLaura De ClerckSofie Vande CasteeleAn StaesFrancis ImpensDieter DeforceLennart Martens et al.

A1 Journal Article in PROTEOMICS

Spatio-temporal patterns in the gene expression of the calanoid copepod Temora longicornis in the Belgian part of the North Sea

Ilias SemmouriKarel De SchamphelaereFilip Van NieuwerburghDieter DeforceColin JanssenJana Asselman

A1 Journal Article in MARINE ENVIRONMENTAL RESEARCH

Strategy for the identification of micro-organisms producing food and feed products : bacteria producing food enzymes as study case

Marie DeckersKevin VannesteRaf WinandSigrid C. J. De KeersmaeckerSarah DenayerMarc HeyndrickxDieter DeforceMarie-Alice FraitureNancy H. C. Roosens

A1 Journal Article in FOOD CHEMISTRY

Validation of a new LMS (lactate minimum speed) exercise test for optimal assessment of the aerobic window of sport horses

Lorie De MaréBerit BoshuizenConstance De meeûsLukas PlanckeCarmen Vidal Moreno de VegaJean de OliveiraYannick GansemansFilip Van NieuwerburghDieter DeforceCatherine Delesalle

2019

A multi-omics analysis of the grapevine pathogen Lasiodiplodia theobromae reveals that temperature affects the expression of virulence- and pathogenicity-related genes

Carina FelixRodrigo Silva MenesesMicael F. M. GoncalvesLaurentijn TillemanAna S. DuarteJesus V. Jorrin-NovoYves Van de PeerDieter DeforceFilip Van NieuwerburghAna C. Esteves et al.

A1 Journal Article in SCIENTIFIC REPORTS

Bovine embryo-secreted microRNA-30c is a potential non-invasive biomarker for hampered preimplantation developmental competence

Xiaoyuan LinEvy BeckersSéan Mc CaffertyYannick GansemansKatarzyna Joanna Szymańska-VandendriesscheKrishna PavaniJoão Portela CataniFilip Van NieuwerburghDieter DeforcePetra De Sutter et al.

A1 Journal Article in FRONTIERS IN GENETICS

Bta-miR-10b secreted by bovine embryos negatively impacts preimplantation embryo quality

Xiaoyuan LinKrishna PavaniKatrien SmitsDieter DeforceBjörn HeindryckxAnn Van SoomLuc Peelman

A1 Journal Article in FRONTIERS IN GENETICS

Characterization of porcine hepatic and intestinal drug metabolizing CYP450 : comparison with human orthologues from a quantitative, activity and selectivity perspective

Wim SchelstraeteLaura De ClerckElisabeth GovaertJoske MillecamMathias DevreeseDieter DeforceJan Van BocxlaerSiska Croubels

A1 Journal Article in SCIENTIFIC REPORTS

Comparative analysis of different nuclear transfer techniques to prevent the transmission of mitochondrial DNA variants

Maoxing TangR ReddyYannick GansemansMargot Van der JeughtAnnekatrien BoelPanagiotis StamatiadisRudy Van CosterDieter DeforceFilip Van NieuwerburghPetra De Sutter et al.

Comparative analysis of different nuclear transfer techniques to prevent the transmission of mitochondrial DNA variants

Maoxing TangRamesh GuggillaYannick GansemansMargot Van der JeughtAnnekatrien BoelMina PopovicPanagiotis StamatiadisMinerva Ferrer BuitragoVanessa ThysRudy Van Coster et al.

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Comparison of seven contemporary pharmacogenetic assays with the PharmGKB database

Laurentijn TillemanDieter DeforceFilip Van Nieuwerburgh

Contemporary pharmacogenetic assays in view of the PharmGKB database

Laurentijn TillemanJana WeymaereBjörn HeindryckxDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in PHARMACOGENOMICS

Deletion of mucosa-associated lymphoid tissue lymphoma translocation protein 1 in mouse T cells protects against development of autoimmune arthritis but leads to spontaneous osteoporosis

Elisabeth GilisDjoere GaublommeJens StaalKoen VenkenMaarten DhaenensStijn LambrechtJulie CoudenysTine DecruyNadia SchryversYasmine Driege et al.

A1 Journal Article in ARTHRITIS & RHEUMATOLOGY

Do no harm : patient-centered forensic examinations upon sexual assault

Ines KeygnaertSaar BaertDieter DeforceDavid Van HoofstatKristien RoelensRonny DecorteJoke Wuestenbergs

Dual RNA sequencing of Vitis vinifera during Lasiodiplodia theobromae infection unveils host-pathogen interactions

Micael FM GonçalvesRui B NunesLaurentijn TillemanYves Van de PeerDieter DeforceFilip Van NieuwerburghAna C EstevesArtur Alves

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endometrial stromal cell proteome mapping in repeated implantation failure and recurrent pregnancy loss cases and fertile women

Lien DhaenensSylvie LiermanLaura De ClerckElisabeth GovaertDieter DeforceKelly TillemanPetra De Sutter

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

Forensic lab-on-a-chip DNA analysis

Senne CornelisDieter DeforceFilip Van NieuwerburghLiesbeth Lagae

Forensic tri-allelic SNP genotyping using nanopore sequencing

Senne CornelisYannick GansemansAnn-Sophie Vander PlaetsenJana WeymaereSander WillemsDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

Gloria MilaniFilip MatthijssensWouter Van LoockeKaat DurinckJuliette RoelsSofie PeirsMorgan ThénozTim PietersLindy ReunesBéatrice Lintermans et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Genome-wide stress responses to copper and arsenic in a field population of Daphnia

Jana AsselmanIlias SemmouriCraig JacksonNathan R KeithFilip Van NieuwerburghDieter DeforceJoseph R ShawKarel De Schamphelaere

A1 Journal Article in ENVIRONMENTAL SCIENCE & TECHNOLOGY

Honey bee predisposition of resistance to ubiquitous mite infestations

Bart BroeckxLina De SmetTjeerd BlacquièreKevin MaebeMikalaï KhalenkowMario Van PouckeBjorn DahlePeter NeumannKim Bach NguyenGuy Smagghe et al.

A1 Journal Article in SCIENTIFIC REPORTS

Host intestinal biomarker identification in a gut leakage model in broilers

Fien De MeyerVenessa EeckhautRichard DucatelleMaarten DhaenensSimon DaledAnnelike DedeurwaerderMaarten De GussemFreddy HaesebrouckDieter DeforceFilip Van Immerseel

A1 Journal Article in VETERINARY RESEARCH

Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics

Aurélie CrabbéLisa OstynSorien StaelensCharlotte RigautsMartijn RisseeuwMaarten DhaenensSimon DaledHeleen Van AckerDieter DeforceSerge Van Calenbergh et al.

A1 Journal Article in PLOS PATHOGENS

Influence of microbiota in the susceptibility of parasitic wasps to abamectin insecticide : deep sequencing, esterase and toxicity tests

María del Mar FernándezIvan MeeusAnnelies BillietFilip Van NieuwerburghDieter DeforcePeter VandammeElisa ViñuelaGuy Smagghe

A1 Journal Article in PEST MANAGEMENT SCIENCE

Integrative proteomic profiling reveals PRC2-dependent epigenetic crosstalk maintains ground-state pluripotency

Guido van MierloRené AM DirksLaura De ClerckArie B BrinkmanMichelle HuthSusan L KloetNehmé SaksoukLeonie I KroezeSander WillemsMatthias Farlik et al.

A1 Journal Article in CELL STEM CELL

Intracellular localisation of platelet-activating factor during mammalian embryo development in vitro : a comparison of cattle, mouse and human

Lynn VandenbergheBjörn HeindryckxKatrien SmitsMina PopovicKatarzyna Joanna Szymańska-VandendriesscheDavina BonteLuc PeelmanDieter DeforcePetra De SutterAnn Van Soom et al.

A1 Journal Article in REPRODUCTION FERTILITY AND DEVELOPMENT

Prevention is better than cure : non-targeted and sensitive screening of impurities in plasma-derived immunoglobulin with mass spectrometry-based proteomics

Franck LimonierDieter DeforceMyriam SneyersMaarten Dhaenens

Silicon µPCR chip for forensic STR profiling with hybeacon probe melting curves

Senne CornelisOlivier TytgatMaarten FauvartYannick GansemansAnn-Sophie Vander PlaetsenRodrigo S WiederkehrDieter DeforceFilip Van NieuwerburghTim Stakenborg

A1 Journal Article in SCIENTIFIC REPORTS

Small RNA NcS27 co-regulates utilization of carbon sources in Burkholderia cenocepacia J2315

Andrea SassStijn De WaeleSimon DaledBart DevreeseDieter DeforceFilip Van NieuwerburghTom Coenye

A1 Journal Article in MICROBIOLOGY-SGM

The role of small proteins in Burkholderia cenocepacia J2315 biofilm formation, persistence and intracellular growth

Heleen Van AckerAurélie CrabbéDukas JurėnasLisa OstynAndrea SassSimon DaledMaarten DhaenensDieter DeforceEline TeirlinckHerlinde De Keersmaecker et al.

A2 Journal Article in BIOFILM

The transcriptome of the marine calanoid copepod Temora longicornis under heat stress and recovery

Ilias SemmouriJana AsselmanFilip Van NieuwerburghDieter DeforceColin JanssenKarel De Schamphelaere

A1 Journal Article in MARINE ENVIRONMENTAL RESEARCH

The use of pronuclear transfer to overcome infertility disorders in mice

Björn HeindryckxAnnekatrien BoelPanagiotis StamatiadisMargot Van der JeughtRamesh GuggillaDieter DeforceRudy Van CosterPetra De Sutter

Tracking changes in the histone modification pattern by untargeted mass spectrometry : how naïve are human embryonic stem cells and data-dependent acquisition?

Laura De ClerckDieter DeforceMaarten Dhaenens

Transgenerational inheritance of DNA hypomethylation in Daphnia magna in response to salinity stress

Guilherme JeremiasJoão Alves BarbosaSérgio MarquesKarel De SchamphelaereFilip Van NieuwerburghDieter DeforceFernando GonçalvesJoana PereiraJana Asselman

Truncating SLC12A6 variants cause different clinical phenotypes in humans and dogs

Mario Van PouckeKimberley SteeLaurien SonckEmmelie StockLeslie BosselerJo Van DorpeFilip Van NieuwerburghDieter DeforceLuc PeelmanLuc Van Ham et al.

A1 Journal Article in EUROPEAN JOURNAL OF HUMAN GENETICS

Untargeted histone profiling during naive conversion uncovers conserved modification markers between mouse and human

Laura De ClerckJasin TaelmanMina PopovicSander WillemsMargot Van der JeughtBjörn HeindryckxPetra De SutterHendrik MarksDieter DeforceMaarten Dhaenens

A1 Journal Article in SCIENTIFIC REPORTS

WNT inhibition and increased fibroblast growth factor signaling promotes derivation of less heterogeneous primed human embryonic stem cells, compatible with differentiation

Jasin TaelmanMina PopovicMonika BialeckaLaurentijn TillemanSharat WarrierMargot Van der JeughtBjörn MentenDieter DeforcePetra De SutterFilip Van Nieuwerburgh et al.

A1 Journal Article in STEM CELLS AND DEVELOPMENT

hSWATH : unlocking SWATH’s full potential for an untargeted histone perspective

Laura De ClerckSander WillemsRoberta NoberiniCamilla RestelliniBart Van PuyveldeSimon DaledTiziana BonaldiDieter DeforceMaarten Dhaenens

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

2018

A different gut microbial community between larvae and adults of a wild bumblebee nest (Bombus pascuorum)

Anneleen ParmentierIvan MeeusFilip Van NieuwerburghDieter DeforcePeter VandammeGuy Smagghe

A1 Journal Article in INSECT SCIENCE

A prokaryotic-eukaryotic relation in the fat body of Bombus terrestris

Anneleen ParmentierAnnelies BillietGuy SmagghePeter VandammeDieter DeforceFilip Van NieuwerburghIvan Meeus

A1 Journal Article in ENVIRONMENTAL MICROBIOLOGY REPORTS

Accurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits

Mattias Van HeetveldeMieke Van BockstalBruce PoppeKathleen LambeinToon RosseelLilit AtanesyanDieter DeforceIvo Van Den BergheKim De LeeneerJo Van Dorpe et al.

A1 Journal Article in CANCER LETTERS

Chromosomal mosaicism in human blastocysts : the ultimate challenge of preimplantation genetic testing?

Mina PopovicAnnelies DheedeneCHRISTODOULOS CHRISTODOULOUJasin TaelmanLien DhaenensFilip Van NieuwerburghDieter DeforceEtienne Van den AbbeelPetra De SutterBjörn Menten et al.

A1 Journal Article in HUMAN REPRODUCTION

Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background

Sabitri GhimireMargot Van der JeughtJitesh NeupaneMatthias S RoostJasper AnckaertMina PopovicFilip Van NieuwerburghPieter MestdaghJo VandesompeleDieter Deforce et al.

A1 Journal Article in SCIENTIFIC REPORTS

Comparison of three methods to quantify laxity in the canine hip joint

Bart BroeckxAldo VezzoniEvelien BogaertsMiléva BertalTim BosmansEmmelie StockDieter DeforceLuc PeelmanJimmy Saunders

A1 Journal Article in VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY

Effect of β-adrenergic receptor agents on cardiac structure and function and whole-body gene expression in Daphnia magna

Tae-Yong JeongJana AsselmanKarel De SchamphelaereFilip Van NieuwerburghDieter DeforceSang Don Kim

A1 Journal Article in ENVIRONMENTAL POLLUTION

Estimating the reliability of low-abundant signals and limited replicate measurements through MS2 peak area in SWATH

Franck LimonierSander WillemsGeneviève WaeterloosMyriam SneyersMaarten DhaenensDieter Deforce

A1 Journal Article in PROTEOMICS

Impact of pluripotency state and Activin A supplementation on derivation of primordial germ cell-like cells from human

Swati MishraMargot Van der JeughtJasin TaelmanMina PopovicKatarzyna Joanna Szymańska-VandendriesscheDieter DeforcePetra De SutterSusana Marina Chuva de Sousa LopesBjörn Heindryckx

Intra- and inter-observer variability of measurements of the laxity index on stress radiographs performed with the Vezzoni-modified Badertscher hip distension device

Miléva BertalAldo VezzoniBlandine HoudellierEvelien BogaertsEmmelie StockIngeborgh PolisDieter DeforceJimmy SaundersBart Broeckx

A1 Journal Article in VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY

Massively parallel sequencing of micro-manipulated cells targeting a comprehensive panel of disease-causing genes : a comparative evaluation of upstream whole-genome amplification methods

Lieselot DeleyeYannick GansemansDieter De ConinckFilip Van NieuwerburghDieter Deforce

A1 Journal Article in PLOS ONE

Maturation of hepatic cytochrome P450 enzymes in conventional pigs : fact or fiction?

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

Maturation of hepatic cytochrome P450 enzymes in conventional pigs : the added value of proteomics

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

Maturation of hepatic cytochrome P450 enzymes in conventional pigs as model for preclinical paediatric drug research

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

Methods matter : towards the implementation of label-free MS in the context of hESC histone epigenetics

Elisabeth GovaertDieter DeforceMaarten Dhaenens

Microfluidics-based liquid chromatography/mass spectrometry multiple reaction monitoring approach for the relative quantification of Burkholderia cenocepacia secreted virulence factors

Sofie DepluverezSimon DaledStijn De WaeleSören PlanckaertJolien SchoovaertsDieter DeforceBart Devreese

A1 Journal Article in RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Multiplex STR amplification sensitivity in a silicon microchip

Senne CornelisMaarten FauvartYannick GansemansAnn-Sophie Vander PlaetsenFrederik ColleRodrigo S WiederkehrDieter DeforceTim StakenborgFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

PLCz knock-out sperm reveals the sole effect of altering calcium signals during assisted oocyte activation on later mouse embryogenesis

Minerva Ferrer BuitragoLaurentijn TillemanVanessa ThysA HachemFilip Van NieuwerburghLuc LeybaertPetra De SutterDieter DeforceJ ParringtonBjörn Heindryckx

Plasma functionalization of polycaprolactone nanofibers changes protein interactions with cells, resulting in increased cell viability

Mahtab AsadianMaarten DhaenensYuliia OnyshchenkoStijn De WaeleHeidi DeclercqPieter CoolsBart DevreeseDieter DeforceRino MorentNathalie De Geyter

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Platelet-activating factor acetylhydrolase 1B3 (PAFAH1 B3) is required for the formation of the meiotic spindle during in vitro oocyte maturation

Lynn VandenbergheBjörn HeindryckxKatrien SmitsKatarzyna Joanna Szymańska-VandendriesscheNerea Ortiz EscribanoMinerva Ferrer BuitragoKrishna PavaniLuc PeelmanDieter DeforcePetra De Sutter et al.

A1 Journal Article in REPRODUCTION FERTILITY AND DEVELOPMENT

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

Renate De SmedtSofie PeirsJulie MorscioFilip MatthijssensJuliette RoelsLindy ReunesBéatrice LintermansSteven GoossensTim LammensNadine Van Roy et al.

A1 Journal Article in HAEMATOLOGICA

Proceedings of the EuBIC developer's meeting 2018

Sander WillemsDavid BouyssiéDieter DeforceViktoria DorferVladimir GorshkovDominik KopczynskiKris LaukensMarie Locard-PauletVeit SchwämmleJulian Uszkoreit et al.

A1 Journal Article in JOURNAL OF PROTEOMICS

Proteins involved in embryo-maternal interaction around the signalling of maternal recognition of pregnancy in the horse

Katrien SmitsSander WillemsKatleen Van SteendamMargot Van de VeldeValérie De LangeCyrillus VerversKim RoelsJan GovaereFilip Van NieuwerburghLuc Peelman et al.

A1 Journal Article in SCIENTIFIC REPORTS

Reply to the letter: ‘Le scientisme, c'est la prétention indue au monopole de vérité, alors que le propre de la science c'est de dire: il n'y a pas de monopole’ (Edgar Morin)

Bart BroeckxAldo VezzoniEvelien BogaertsMiléva BertalTim BosmansEmmelie StockDieter DeforceLuc PeelmanJimmy Saunders

A1 Journal Article in VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY

Short tandem repeat analysis after whole genome amplification of single B-lymphoblastoid cells

Lieselot DeleyeAnn-Sophie Vander PlaetsenJana WeymaereDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Skin mucosome activity as an indicator of Batrachochytrium salamandrivorans susceptibility in salamanders

Hannah Keely SmithFrank PasmansMaarten DhaenensDieter DeforceDries BonteKris VerheyenLuc LensAn Martel

A1 Journal Article in PLOS ONE

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

Bieke DecaestekerGeertrui DeneckerChristophe Van NesteEmmy M DolmanWouter Van LoockeMoritz GartlgruberCarolina de Carvalho NunesFanny De VloedPauline DepuydtKaren Verboom et al.

A1 Journal Article in NATURE COMMUNICATIONS

The Chara genome : secondary complexity and implications for plant terrestrialization

Tomoaki NishiyamaHidetoshi SakayamaJan de VriesHenrik BuschmannDenis Saint-MarcouxKristian K UllrichFabian B HaasLisa VanderstraetenDirk BeckerDaniel Lang et al.

A1 Journal Article in CELL

The ontogeny of cytochrome P450 enzyme activity and protein abundance in conventional pigs in support of preclinical pediatric drug research

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

The small RNA ncS35 regulates growth in Burkholderia cenocepacia J2315

Sanne KiekensAndrea SassFilip Van NieuwerburghDieter DeforceTom Coenye

A1 Journal Article in MSPHERE

Transcriptional landscape changes during human embryonic stem cell derivation

Sharat WarrierJasin TaelmanLaurentijn TillemanMargot Van der JeughtGalbha DuggalSylvie LiermanMina PopovicAnn Van SoomLuc PeelmanFilip Van Nieuwerburgh et al.

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Transgenerational inheritance of DNA hypomethylation in Daphnia magna in response to salinity stress

Guilherme JeremiasJoão BarbosaSergio MarquesKarel De SchamphelaereFilip Van NieuwerburghDieter DeforceFernando GonçalvesJoana PereiraJana Asselman

A1 Journal Article in ENVIRONMENTAL SCIENCE & TECHNOLOGY

Unravelling the molecular pathways responsible for sex determination in humans

Jasin TaelmanMina PopovicLaurentijn TillemanMargot Van der JeughtDieter DeforcePetra De SutterFilip Van NieuwerburghBjörn HeindryckxS Chuva De Sousa Lopes

2017

A new approach in pediatric drug design : the development of a pediatric pig model, part II : the maturation of hepatic cytochrome P450 enzymes using enzyme activity and proteomics

Joske MillecamElke GasthuysMathias DevreeseDieter DeforceLies De BockJan Van BocxlaerSiska Croubels

An application of mass spectrometry for quality control of biologicals : highly sensitive profiling of plasma residuals in human plasma-derived immunoglobulin

Franck LimonierKatleen Van SteendamGeneviève WaeterloosKoen BrusselmansMyriam SneyersDieter Deforce

A1 Journal Article in JOURNAL OF PROTEOMICS

An exome sequencing based approach for genome-wide association studies in the dog

Bart BroeckxThomas DerrienStéphanie MottierValentin WucherEdouard CadieuBenoît HédanCéline Le BéguecNadine BotherelKerstin Lindblad-TohJimmy Saunders et al.

A1 Journal Article in SCIENTIFIC REPORTS

An integrated strategy combining DNA walking and NGS to detect GMO

Marie-Alice FraiturePhilippe HermanNina PapazovaMarc De LooseDieter DeforceTom RuttinkNancy Roosens

A1 Journal Article in FOOD CHEMISTRY

Autocrine embryotropins revisited : how do embryos talk to each other in vitro when cultured in groups?

Eline WydoogheLeen VandaeleSonia Heras GarcíaPetra De SutterDieter DeforceLuc PeelmanCatharina De SchauwerAnn Van Soom

A1 Journal Article in BIOLOGICAL REVIEWS

Can vitrified-thawed mouse oocytes be efficiently used to determine the oocyte activation potential of human sperm?

Davina BonteMinerva Ferrer BuitragoVanessa ThysDieter DeforceLuc LeybaertPetra De SutterBjörn Heindryckx

Colony contact contributes to the diversity of gut bacteria in bumblebees (Bombus terrestris)

Annelies BillietIvan MeeusFilip Van NieuwerburghDieter DeforceFelix WäckersGuy Smagghe

A1 Journal Article in INSECT SCIENCE

Comparison of fractionation proteomics for local SWATH library building

Elisabeth GovaertKatleen Van SteendamSander WillemsLiesbeth VossaertMaarten DhaenensDieter Deforce

A1 Journal Article in PROTEOMICS

Comprehensive comparison of inner cell mass and trophectoderm reveals the complex nature of chromosomal mosaicism in human embryos

Mina PopovicAnnelies DheedeneCHRISTODOULOS CHRISTODOULOUMargot Van der JeughtFilip Van NieuwerburghDieter DeforcePetra De SutterEtienne Van den AbbeelBjörn MentenBjörn Heindryckx

Direct comparison of distinct naive pluripotent states in human embryonic stem cells

Sharat WarrierMargot Van der JeughtGalbha DuggalLaurentijn TillemanElla SutherlandJasin TaelmanMina PopovicSylvie LiermanSusana Marina Chuva de Sousa LopesAnn Van Soom et al.

A1 Journal Article in NATURE COMMUNICATIONS

Effect of aleurone on equine fecal microbiome and glucose metabolism in non-training horses

Berit BoshuizenConstance De meeûsFilip Van NieuwerburghDieter DeforceJean de OlivieraLaura Van HauweCatherine Delesalle

Epigenetic sampling effects : nephrectomy modifies the clear cell renal cell cancer methylome

Christophe Van NesteAlexander LairdFiach O’MahonyWim Van CriekingeDieter DeforceFilip Van NieuwerburghThomas PowlesDavid J HarrisonGrant D StewartTim De Meyer

A1 Journal Article in CELLULAR ONCOLOGY

Flagging false positives following untargeted LCMS characterization of histone PTM combinations

Sander WillemsMaarten DhaenensElisabeth GovaertLaura De ClerckPaulien MeertChristophe Van NesteFilip Van NieuwerburghDieter Deforce

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Forensic SNP genotyping using nanopore MinION sequencing

Senne CornelisYannick GansemansLieselot DeleyeDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Infections of virulent and avirulent viruses differentially influenced the expression of dicer-1, ago-1, and microRNAs in Bombus terrestris

Jinzhi NiuIvan MeeusDieter De ConinckDieter DeforceKayvan EtebariSassan AsgariGuy Smagghe

A1 Journal Article in SCIENTIFIC REPORTS

Massively parallel sequencing in preimplantation and prenatal genetic diagnosis

Lieselot DeleyeFilip Van NieuwerburghDieter Deforce

Metabolic activity, urease production, antibiotic resistance and virulence in dual species biofilms of Staphylococcus epidermidis and Staphylococcus aureus

Ilse VandecandelaereFilip Van NieuwerburghDieter DeforceTom Coenye

A1 Journal Article in PLOS ONE

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

Steven GoossensSofie PeirsWouter Van LoockeJueqiong WangMina TakawyFilip MatthijssensStefan E SondereggerKatharina HaighThao NguyenNiels Vandamme et al.

A1 Journal Article in BLOOD

Origins of human embryonic stem cell fate : role of the post inner cell mass intermediate

Sharat WarrierMina PopovicJasin TaelmanLaurentijn TillemanSylvie LiermanMinerva Ferrer BuitragoS. Chuva De Sousa LopesAnn Van SoomLuc PeelmanFilip Van Nieuwerburgh et al.

Performance of four modern whole genome amplification methods for copy number variant detection in single cells

Lieselot DeleyeLaurentijn TillemanAnn-Sophie Vander PlaetsenSenne CornelisDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Phenobarbital or potassium bromide as an add-on antiepileptic drug for the management of canine idiopathic epilepsy refractory to imepitoin

Emilie RoyauxLuc Van HamBart BroeckxIris Van SoensIngrid GielenDieter DeforceSofie Bhatti

A1 Journal Article in VETERINARY JOURNAL

Preimplantation genetic diagnosis for chromosomal rearrangements with the use of array comparative genomic hybridization at the blastocyst stage

CHRISTODOULOS CHRISTODOULOUAnnelies DheedeneBjörn HeindryckxFilip Van NieuwerburghDieter DeforcePetra De SutterBjörn MentenEtienne Van den Abbeel

A1 Journal Article in FERTILITY AND STERILITY

Proteome of equine oviducal fluid : effects of ovulation and pregnancy

Katrien SmitsHilde NelisKatleen Van SteendamJan GovaereKim RoelsCyrillus VerversBart LeemansEline WydoogheDieter DeforceAnn Van Soom

A1 Journal Article in REPRODUCTION FERTILITY AND DEVELOPMENT

RMNE calculation in forensic profiles with a high number of loci and allelic drop-outs using polynomial expansion

Sander WillemsSenne CornelisYannick GansemansBart BroeckxDieter De ConinckChristophe Van NesteMaarten DhaenensDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods

Ann-Sophie Vander PlaetsenLieselot DeleyeSenne CornelisLaurentijn TillemanFilip Van NieuwerburghDieter Deforce

A1 Journal Article in SCIENTIFIC REPORTS

Second hit landscape in BRCA-associated breast cancer

Mattias Van HeetveldeMieke Van BockstalTrees LepezSteve LefeverLeen PietersKathleen LambeinMarleen PraetIvo Van Den BergheFrauke CoppietersNadine Van Roy et al.

Second hit landscape in BRCA1/2-associated breast cancer

Mattias Van HeetveldeMieke Van BockstalTrees LepezKathleen LambeinDieter DeforceAnne VralBruce PoppeKim De LeeneerJo Van DorpeKathleen Claes

The ontogeny of hepatic cytochrome P450 enzymes in conventional pigs using enzyme activity and proteomics

Joske MillecamElke GasthuysMathias DevreeseDieter DeforceJan Van BocxlaerSiska Croubels

The transcriptome of Mycobacterium tuberculosis in a lipid-rich dormancy model through RNAseq analysis

Diana Angelica Aguilar AyalaLaurentijn TillemanFilip Van NieuwerburghDieter DeforceJuan Carlos PalominoPeter VandammeJorge A Gonzalez-Y-MerchandAnandi Martin

A1 Journal Article in SCIENTIFIC REPORTS

Using variant databases for variant prioritization and to detect erroneous genotype-phenotype associations

Bart BroeckxLuc PeelmanJimmy SaundersDieter DeforceLieven Clement

A1 Journal Article in BMC BIOINFORMATICS

Vitrified-thawed mouse oocytes can be efficiently used to determine the oocyte activation potential of human sperm

Davina BonteMinerva Ferrer BuitragoVanessa ThysDieter DeforceLuc LeybaertPetra De SutterBjörn Heindryckx

Wnt inhibition during hESC culture provides an improved pluripotent state starting point for directed differentiation

Jasin TaelmanLaurentijn TillemanFilip Van NieuwerburghSharat WarrierMina PopovicMargot Van der JeughtDieter DeforcePetra De SutterBjörn HeindryckxSusana Marina Chuva de Sousa Lopes

2016

Assessing the impact of minimizing arginine conversion in fully defined SILAC culture medium in human embryonic stem cells

Ellen ScheerlinckKatleen Van SteendamSimon DaledElisabeth GovaertLiesbeth VossaertPaulien MeertFilip Van NieuwerburghAnn Van SoomLuc PeelmanPetra De Sutter et al.

A1 Journal Article in PROTEOMICS

BMP-SMAD signaling regulates lineage priming, but is dispensable for self-renewal in mouse embryonic stem cells

Maria Gomes FernandesRuben DriesMatthias S RoostStefan SemrauAna de Melo BernardoRichard P DavisRamprasad RamakrishnanKaroly SzuhaiElke MaasLieve Umans et al.

A1 Journal Article in STEM CELL REPORTS

Biotech rice : current developments and future detection challenges in food and feed chain

Marie-Alice FraitureNancy RoosensIsabel TaverniersMarc De LooseDieter DeforcePhilippe Herman

A1 Journal Article in TRENDS IN FOOD SCIENCE & TECHNOLOGY

CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis

Thomas NaertRobin ColpaertTom Van NieuwenhuysenDionysia DimitrakopoulouJannick LeoenJurgen HaustraeteAnnekatrien BoelWouter SteyaertTrees LepezDieter Deforce et al.

A1 Journal Article in SCIENTIFIC REPORTS

Computed tomographic findings in canine elbows arthroscopically diagnosed with erosion of the medial compartment : an analytical method comparison study

Eva CoppietersBernadette Van RyssenHenri van BreeGeert VerhoevenBart BroeckxEvelien de BakkerDieter DeforceIngrid Gielen

A1 Journal Article in VETERINARY RADIOLOGY & ULTRASOUND

Divergence between the highly virulent zoonotic pathogen Helicobacter heilmannii and its closest relative, the low-virulence 'Helicobacter ailurogastricus' sp. nov.

Myrthe JoostenSara LindénMirko RossiAlfred Chin Yen TayEmma SkoogMédea PadraFanny PetersTim PerkinsPeter VandammeFilip Van Nieuwerburgh et al.

A1 Journal Article in INFECTION AND IMMUNITY

Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer

Grant D StewartThomas PowlesChristophe Van NesteAlison MeynertFiach O'MahonyAlexander LairdDieter DeforceFilip Van NieuwerburghGeert TrooskensWim Van Criekinge et al.

A1 Journal Article in ONCOTARGET

Extracting histones for the specific purpose of label-free MS

Elisabeth GovaertKatleen Van SteendamEllen ScheerlinckLiesbeth VossaertPaulien MeertMartina StellaSander WillemsLaura De ClerckMaarten DhaenensDieter Deforce

A1 Journal Article in PROTEOMICS

Forensic Loci Allele Database (FLAD) : automatically generated, permanent identifiers for sequenced forensic alleles

Christophe Van NesteWim Van CriekingeDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Histone code caution : clipping and proper propionylation

Paulien MeertDieter DeforceMaarten DhaenensLiesbeth Vossaert

Host stress drives Salmonella recrudescence

Elin VerbruggheMaarten DhaenensBregje LeymanFilip BoyenNeil ShearerAlexander Van ParysRoel HaesendonckWim BertHerman FavoreelDieter Deforce et al.

A1 Journal Article in SCIENTIFIC REPORTS

Host stress drives Salmonella recrudescence (vol 6, 20849, 2016)

Elin VerbruggheMaarten DhaenensBregje LeymanFilip BoyenNeil ShearerAlexander Van ParysRoel HaesendonckWim BertHerman FavoreelDieter Deforce et al.

Human embryonic stem cells : from the follow-up of pluripotency to quantitative peptide analysis

Ellen ScheerlinckDieter DeforceKatleen Van SteendamMaarten Dhaenens

Impact of sugar syrup and pollen diet on the bacterial diversity in the gut of indoor-reared bumblebees (Bombus terrestris)

Annelies BillietIvan MeeusFilip Van NieuwerburghDieter DeforceFelix WäckersGuy Smagghe

A1 Journal Article in APIDOLOGIE

In vivo study of Dicer-2-mediated immune response of the small interfering RNA pathway upon systemic infections of virulent and avirulent viruses in Bombus terrestris

Jinzhi NiuGuy SmaggheDieter De ConinckFilip Van NieuwerburghDieter DeforceIvan Meeus

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detection using massively parallel sequencing

Lieselot DeleyeDieter De ConinckAnnelies DheedenePetra De SutterBjörn MentenDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Phenobarbital or potassium bromide as an add-on anti-epileptic drug for the management of canine idiopathic epilepsy refractory to imepitoin

Emilie RoyauxLuc Van HamBart BroeckxIris Van SoensIngrid GielenDieter DeforceSofie Bhatti

Preimplantation genetic diagnosis (PGD) for translocation carriers using whole genome screening by microarray analysis at the blastocyst stage

CHRISTODOULOS CHRISTODOULOUAnnelies DheedeneIlse De CrooBjörn HeindryckxLieselot DeleyeFilip Van NieuwerburghDieter DeforcePetra De SutterBjörn MentenEtienne Van den Abbeel

Progressive juvenile nephropathy in an 11 week old bloodhound

Han VersnaeyenPieter DefauwBart BroeckxDieter DeforceLeslie BosselerKoen Chiers

Spontaneous protein adsorption on graphene oxide nanosheets allowing efficient intracellular vaccine protein delivery

Hui LiKaat FierensZhiyue ZhangNane VanparijsMartijn SchuijsKatleen Van SteendamNatalia Feiner GraciaRiet De RyckeThomas De BeerAns De Beuckelaer et al.

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Statistical framework for detection of genetically modified organisms based on Next Generation Sequencing

Sander WillemsMarie-Alice FraitureDieter DeforceSigrid De KeersmaeckerPhilippe HermanMarc De LooseTom RuttinkFilip Van NieuwerburghNancy Roosens

A1 Journal Article in FOOD CHEMISTRY

Strategies to detect unauthorized GMO in the food and feed chain

Marie-Alice FraitureDieter DeforceNancy RoosensMarc De Loose

Suboptimal culture conditions induce more deviations in gene expression in male than female bovine blastocysts

Sonia Heras GarcíaDieter De ConinckMario Van PouckeKaren GoossensOsvaldo Américo Bogado PascottiniFilip Van NieuwerburghDieter DeforcePetra De SutterJo LeroyAlfonso Gutierrez-Adan et al.

A1 Journal Article in BMC GENOMICS

Tackling aspecific side reactions during histone propionylation: the promise of reversing overpropionylation

Paulien MeertSebastiaan DierickxElisabeth GovaertLaura De ClerckSander WillemsMaarten DhaenensDieter Deforce

A1 Journal Article in PROTEOMICS

The equine embryo influences immune related gene expression in the oviduct

Katrien SmitsDieter De ConinckFilip Van NieuwerburghJan GovaereMario Van PouckeLuc PeelmanDieter DeforceAnn Van Soom

A1 Journal Article in BIOLOGY OF REPRODUCTION

Thorough second hit analysis in BRCA1/2 associated breast cancer

Mattias Van HeetveldeTrees LepezLeen PietersSteve LefeverJo Van DorpeKathleen LambeinMarleen Praetivo Van Den BergheFrauke CoppietersJo Vandesompele et al.

Thorough second-hit analysis in BRCA1/2-associated breast cancer

Mattias Van HeetveldeTrees LepezLeen PietersSteve LefeverJo Van DorpeKathleen LambeinMarleen PraetIvo Van Den BergheFrauke CoppietersJo Vandesompele et al.

Toward the most ideal case-control design with related and unrelated dogs in whole-exome sequencing studies

Bart BroeckxFrank CoopmanGeert VerhoevenSarah De KeulenaerEllen De MeesterValérie BavegemsPascale SmetsBernadette Van RyssenFilip Van NieuwerburghDieter Deforce

A1 Journal Article in ANIMAL GENETICS

Uncovering the novel role of mTORC2 subunit of the PI3K/AKT/mTORC pathway in establishing naive pluripotency in human embryonic stem cells

Sharat WarrierMargot Van der JeughtGalbha DuggalJasin TaelmanSylvie LiermanSusana Marina Chuva de Sousa LopesAnn Van SoomLuc PeelmanFilip Van NieuwerburghDieter De Coninck et al.

Unique long non-coding RNA expression signature in ETV6/RUNX1-Driven B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerlooseWouter Van LoockeAnnelynn WallaertAlina FersterMarleen BakkusGeneviève PlatEric DelabesseAnne UyttebroeckFilip Van Nieuwerburgh et al.

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerlooseWouter Van LoockeAnnelynn WallaertHetty HelsmoortelAlina FersterMarleen BakkusGeneviève PlatEric DelabesseAnne Uyttebroeck et al.

A1 Journal Article in ONCOTARGET

Zinc chelation promotes oocyte activation in human oocytes

Davina BonteMinerva Ferrer BuitragoEtienne Van den AbbeelMargot Van der JeughtDieter DeforceLuc LeybaertPetra De SutterBjörn Heindryckx

2015

16S rRNA Amplicon sequencing demonstrates that indoor-reared bumblebees (Bombus terrestris) harbor a core subset of bacteria normally associated with the wild host

Ivan MeeusLaurian ParmentierAnnelies BillietKevin MaebeFilip Van NieuwerburghDieter DeforceFelix WäckersPeter VandammeGuy Smagghe

A1 Journal Article in PLOS ONE

A doubling of microphytobenthos biomass coincides with a tenfold increase in denitrifier and total bacterial abundances in intertidal sediments of a temperate estuary

Helen DecleyreKim HeylenKoen SabbeBjorn TytgatDieter DeforceFilip Van NieuwerburghCarl Van ColenAnne Willems

A1 Journal Article in PLOS ONE

Alternative routes to induce naive pluripotency in human embryonic stem cells

Galbha DuggalSharat WarrierSabitri GhimireDorien BroekaertMargot Van der JeughtSylvie LiermanTom DerooLuc PeelmanAnn Van SoomMaria Cornelissen et al.

A1 Journal Article in STEM CELLS

An heuristic filtering tool to identify phenotype-associated genetic variants applied to human intellectual disability and canine coat colors

Bart BroeckxFrank CoopmanGeert VerhoevenTim BosmansIngrid GielenWalter DingemanseJimmy SaundersDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in BMC BIOINFORMATICS

Application of small molecules favoring naive pluripotency during human embryonic stem cell derivation

Margot Van der JeughtJasin TaelmanGalbha DuggalSabitri GhimireSylvie LiermanSusana Marina Chuva de Sousa LopesDieter DeforceTom DerooPetra De SutterBjörn Heindryckx

A1 Journal Article in CELLULAR REPROGRAMMING

Canine whole exome sequencing : hip, hip, hurray?: the quest for genetic solutions for phenotypical problems

Bart BroeckxDieter DeforceFrank CoopmanGeert VerhoevenFilip Van Nieuwerburgh

Cellular heterogeneity in the level of mtDNA heteroplasmy in mouse embryonic stem cells

Jitesh NeupaneSabitri GhimireMado VandewoestyneYuechao LuJan GerrisRudy Van CosterTom DerooDieter DeforceStijn VansteelandtPetra De Sutter et al.

A1 Journal Article in CELL REPORTS

Comparative analysis of different culture conditions inducing naive pluripotency in human embryonic stem cells

Sharat WarrierGalbha DuggalJasin TaelmanSylvie LiermanS Chuva de Sousa LopesAnn Van SoomLuc PeelmanFilip Van NieuwerburghDieter De ConinckBjörn Menten et al.

Current and new approaches in GMO detection: challenges and solutions

Marie-Alice FraiturePhilippe HermanIsabel TaverniersMarc De LooseDieter DeforceNancy H Roosens

A1 Journal Article in BIOMED RESEARCH INTERNATIONAL

Derivation conditions affect pluripotency and differentiation propensity of mouse embryonic stem cells

Sabitri GhimireMargot Van der JeughtJitesh NeupaneFilip Van NieuwerburghDieter DeforceSusana Marina Chuva de Sousa LopesPetra De SutterBjörn Heindryckx

Diagnostic and therapeutic approaches to prevent the transmission of heritable mitochondrial diseases

Jitesh NeupanePetra De SutterDieter Deforce

Differential transcriptome analysis of the common shrimp Crangon crangon: special focus on the nuclear receptors and RNAi-related genes

Olivier ChristiaensDaan DelbareChristophe Van NesteNa YuRuben De WildeFilip Van NieuwerburghDieter DeforceKris CooremanGuy Smagghe

A1 Journal Article in GENERAL AND COMPARATIVE ENDOCRINOLOGY

Effect of multiple allelic drop-outs in forensic RMNE calculations

Christophe Van NesteDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Efficiency of exome sequencing for the molecular diagnosis of Pseudoxanthoma Elasticum

Mohammad Jakir HosenFilip Van NieuwerburghWouter SteyaertDieter DeforceLudovic MartinGeorges LeftheriotisAnne De PaepePaul CouckeOlivier Vanakker

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Evaluation of a visualization assay for blood on forensic evidence

Mado VandewoestyneTrees LepezDavid Van HoofstatDieter Deforce

A1 Journal Article in JOURNAL OF FORENSIC SCIENCES

Exogenous supplementation of Activin A enhances germ cell differentiation of human embryonic stem cells

Galbha DuggalBjörn HeindryckxSharat WarrierJasin TaelmanMargot Van der JeughtDieter DeforceSusana Marina Chuva de Sousa LopesPetra De Sutter

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Exposure of Aspergillus fumigatus to T-2 toxin results in a stress response associated with exacerbation of aspergillosis in poultry

Shaoji LiMaarten DhaenensAn GarmynElin VerbrugghePascale Van RooijSarah De SaegerMia EeckhoutRichard DucatelleSiska CroubelsFreddy Haesebrouck et al.

A1 Journal Article in WORLD MYCOTOXIN JOURNAL

Fluoxetine suppresses calcium signaling in human T lymphocytes through depletion of intracellular calcium stores

Veerle GobinMarijke De BockBart BroeckxMaja KiselinovaWard De SpiegelaereLinos VandekerckhoveKatleen Van SteendamLuc LeybaertDieter Deforce

A1 Journal Article in CELL CALCIUM

Forensic massively parallel sequencing data analysis tool: implementation of MyFLq as a standalone web- and Illumina BaseSpace®-application

Christophe Van NesteYannick GansemansDieter De ConinckDavid Van HoofstatWim Van CriekingeDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Genome sequence of Devriesea agamarum, isolated from agamid lizards with dermatitis

Roel HaesendonckFilip Van NieuwerburghFreddy HaesebrouckDieter DeforceFrank PasmansAn Martel

A2 Journal Article in MICROBIOLOGY RESOURCE ANNOUNCEMENTS

Genome-wide transcription start site profiling in biofilm-grown Burkholderia cenocepacia J2315

Andrea SassHeleen Van AckerKonrad FörstnerFilip Van NieuwerburghDieter DeforceJörg VogelTom Coenye

A1 Journal Article in BMC GENOMICS

Heuristic filtering of sequencing variants with the R-package "Mendelian"

Bart BroeckxFrank CoopmanGeert VerhoevenDieter DeforceFilip Van Nieuwerburgh

Histone proteolysis : a proposal for categorization into clipping and degradation

Maarten DhaenensPieter GlibertPaulien MeertLiesbeth VossaertDieter Deforce

A1 Journal Article in BIOESSAYS

Human embryonic stem cells : different shades of pluripotency and differentiation potential

Galbha DuggalPetra De SutterDieter Deforce

Immunoreactive proteins of Brachyspira hyodysenteriae in pigs

Nele De PauwKatleen Van SteendamLien Vande MaeleMaxime MahuFilip BoyenAn MartelFreddy HaesebrouckDieter DeforceFrank Pasmans

Improved canine exome designs, featuring ncRNAs and increased coverage of protein coding genes

Bart BroeckxChristophe HitteFrank CoopmanGeert VerhoevenSarah De KeulenaerEllen De MeesterThomas DerrienJessica AlfoldiKerstin Lindblad-TohTim Bosmans et al.

A1 Journal Article in SCIENTIFIC REPORTS

Integrated DNA walking system to characterize a broad spectrum of GMOs in food/feed matrices

Marie-Alice FraiturePhilippe HermanLoic LefèvreIsabel TaverniersMarc De LooseDieter DeforceNancy H Roosens

A1 Journal Article in BMC BIOTECHNOLOGY

Minimizing technical variation during sample preparation prior to label-free quantitative mass spectrometry

Ellen ScheerlinckMaarten DhaenensAnn Van SoomLuc PeelmanPetra De SutterKatleen Van SteendamDieter Deforce

A1 Journal Article in ANALYTICAL BIOCHEMISTRY

OSC2 and CYP716A14v2 catalyze the biosynthesis of triterpenoids for the cuticle of aerial organs of Artemisia annua

Tessa MosesJacob PollierQian ShenSandra SoetaertJames ReedMarie-Laure ErffelinckFilip Van NieuwerburghRobin Vanden BosscheAnne OsbournJohan M Thevelein et al.

A1 Journal Article in PLANT CELL

Phospho-iTRAQ : assessing isobaric labels for the large-scale study of phosphopeptide stoichiometry

Pieter GlibertPaulien MeertKatleen Van SteendamFilip Van NieuwerburghDieter De ConinckLennart MartensMaarten DhaenensDieter Deforce

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Phospho-iTRAQ data article : assessing isobaric labels for the large-scale study of phosphopeptide stoichiometry

Pieter GlibertPaulien MeertKatleen Van SteendamLennart MartensDieter DeforceMaarten Dhaenens

A2 Journal Article in DATA IN BRIEF

Pitfalls in histone propionylation during bottom-up mass spectrometry analysis

Paulien MeertElisabeth GovaertEllen ScheerlinckMaarten DhaenensDieter Deforce

A1 Journal Article in PROTEOMICS

Porting forensic DNA analysis to deep sequencing

Christophe Van NesteDieter DeforceWim Van CriekingeFilip Van Nieuwerburgh

ScsA as a major driver for increased survival of Salmonella during a stress response

Elin VerbruggheMaarten DhaenensBregje LeymanFilip BoyenNeil ShearerAlexander Van ParysRoel HaesendonckWim BertHerman FavoreelDieter Deforce et al.

Shallow whole genome sequencing is well suited for the detection of chromosomal aberrations in human blastocysts

Lieselot DeleyeAnnelies DheedeneDieter De ConinckTom SanteCHRISTODOULOS CHRISTODOULOUBjörn HeindryckxEtienne Van den AbbeelPetra De SutterDieter DeforceBjörn Menten et al.

A1 Journal Article in FERTILITY AND STERILITY

Tailoring cellular uptake of gold nanoparticles via the hydrophilic-to-hydrophobic ratio of their (co)polymer coating

Zhiyue ZhangKatleen Van SteendamSamarendra MajiLieve BalcaenYulia AnoshkinaQilu ZhangGlenn VanlucheneRiet De RyckeFrank VanhaeckeDieter Deforce et al.

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Teaching old drugs new tricks : selective serotonin reuptake inhibitors as a novel class of immunosuppressants

Veerle GobinDieter DeforceDamiaan DenysKatleen Van Steendam

Transcriptome analysis of Bombyx mori larval midgut during persistent and pathogenic cytoplasmic polyhedrosis virus infection

Anna KolliopoulouFilip Van NieuwerburghDimitrios J StravopodisDieter DeforceLuc SweversGuy Smagghe

A1 Journal Article in PLOS ONE

Validation of a sensitive DNA walking strategy to characterise unauthorised GMOs using model food matrices mimicking common rice products

Marie-Alice FraiturePhilippe HermanIsabel TaverniersMarc De LooseFilip Van NieuwerburghDieter DeforceNancy H. Roosens

A1 Journal Article in FOOD CHEMISTRY

Viral small-RNA analysis of Bombyx mori larval midgut during persistent and pathogenic cytoplasmic polyhedrosis virus infection

Aris ZografidisFilip Van NieuwerburghAnna KolliopoulouKonstantinos Apostolou-KarampelisSteven R HeadDieter DeforceGuy SmaggheLuc Swevers

A1 Journal Article in JOURNAL OF VIROLOGY

Whole exome sequencing as a novel tool for the detection of modifier genes in Pseudoxanthoma elasticum

Eva De VilderFilip Van NieuwerburghDieter DeforceLudovic MartinGeorges LefthériotisPaul CouckeAnne De PaepeOlivier Vanakker

Whole exome sequencing as a novel tool for the detection of modifier genes in pseudoxanthoma elasticum

Eva De VilderFilip Van NieuwerburghDieter DeforceLudovic MartinGeorges LefthériotisAnne De PaepeOlivier Vanakker

Whole exome sequencing the dog

Bart BroeckxChristophe HitteFrank CoopmanGeert VerhoevenSarah De KeulenaerEllen De MeesterThomas DerrienJessica AlfoldiKerstin Lindblad-TohTim Bosmans et al.

Whole genome amplification with SurePlex results in better copy number alteration detection using sequencing data compared to the MALBAC method

Lieselot DeleyeDieter De ConinckCHRISTODOULOS CHRISTODOULOUTom SanteAnnelies DheedeneBjörn HeindryckxEtienne Van den AbbeelPetra De SutterBjörn MentenDieter Deforce et al.

A1 Journal Article in SCIENTIFIC REPORTS

2014

A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuChen QianSylvie LiermanRudy Van CosterJan GerrisTom Deroo et al.

A1 Journal Article in HUMAN REPRODUCTION

An immunogen synthesis strategy for the development of specific anti-deoxynivalenol monoclonal antibodies

Melanie SandersYirong GuoAbhishek IyerYara Ruiz GarciaAnastasia GalvitaArne HeyerickDieter DeforceMartijn RisseeuwSerge Van CalenberghMarc Bracke et al.

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

An innovative and integrated approach based on DNA walking to identify unauthorised GMOs

Marie-Alice FraiturePhilippe HermanIsabel TaverniersMarc De LooseDieter DeforceNancy H Roosens

A1 Journal Article in FOOD CHEMISTRY

Assessment of cellular heterogeneity in the level of mitochondrial DNA heteroplasmy in mouse embryonic stem cells

Jitesh NeupaneBjörn HeindryckxMado VandewoestyneSabitri GhimireYuechao LuRudy Van CosterDieter DeforceTom DerooPetra De Sutter

Assessment of nuclear transfer techniques to prevent the transmission of heritable mitochondrial disorders without compromising embryonic development competence in mice

Jitesh NeupaneMado VandewoestyneSabitri GhimireYuechao LuChen QianRudy Van CosterJan GerrisTom DerooDieter DeforcePetra De Sutter et al.

A1 Journal Article in MITOCHONDRION

Autovaccination confers protection against Devriesea agamarum associated septicemia but not dermatitis in bearded dragons (Pogona vitticeps)

Tom HellebuyckKatleen Van SteendamDieter DeforceMark BlooiFilip Van NieuwerburghEvelien BullaertRichard DucatelleFreddy HaesebrouckFrank PasmansAn Martel

A1 Journal Article in PLOS ONE

Characterization of serotonin transporter expression in human T lymphocytes

Veerle GobinKatleen Van SteendamMaja KiselinovaWard De SpiegelaereLinos VandekerckhoveDieter Deforce

Combined prevalence of inherited skeletal disorders in dog breeds in Belgium

Frank CoopmanBart BroeckxElien VerelstDieter DeforceJimmy SaundersLuc DuchateauGeert Verhoeven

A1 Journal Article in VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY

Detailed method description for noninvasive monitoring of differentiation status of human embryonic stem cells

Ellen ScheerlinckKatleen Van SteendamMado VandewoestyneTrees LepezVeerle GobinPaulien MeertLiesbeth VossaertFilip Van NieuwerburghAnn Van SoomLuc Peelman et al.

A1 Journal Article in ANALYTICAL BIOCHEMISTRY

Development and performance of a targeted whole exome sequencing enrichment kit for the dog (Canis Familiaris Build 3.1)

Bart BroeckxFrank CoopmanGeert VerhoevenValérie BavegemsSarah De KeulenaerEllen De MeesterFilip Van NieuwerburghDieter Deforce

A1 Journal Article in SCIENTIFIC REPORTS

Draft genome sequence of methicillin-resistant Staphylococcus epidermidis strain ET-024, isolated from an endotracheal tube biofilm of a mechanically ventilated patient

Ilse VandecandelaereFilip Van NieuwerburghDieter DeforceHans NelisTom Coenye

A4 Journal Article in GENOME ANNOUNCEMENTS

F4-related mutation and expression analysis of the aminopeptidase N gene in pigs

Tiphanie GoetstouwersMario Van PouckeUt Nguyen VanVesna MelkebeekAnnelies CoddensDieter DeforceEric CoxLuc Peelman

A1 Journal Article in JOURNAL OF ANIMAL SCIENCE

Fast nuclear staining of head hair roots as a screening method for successful STR analysis in forensics

Trees LepezMado VandewoestyneDavid Van HoofstatDieter Deforce

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Growth differentiation factor 15, a marker of lung involvement in systemic sclerosis, is involved in fibrosis development but is not indispensable for fibrosis development

Stijn LambrechtVanessa SmithKatelijne De WildeJulie CoudenysSaskia DecumanDieter DeforceFilip De KeyserDirk Elewaut

A1 Journal Article in ARTHRITIS & RHEUMATOLOGY

Heterologous screening of hybridomas for the development of broad-specific monoclonal antibodies against deoxynivalenol and its analogues

Yirong GuoMelanie SandersAnastasia GalvitaArne HeyerickDieter DeforceMarc BrackeS EreminSarah De Saeger

A1 Journal Article in WORLD MYCOTOXIN JOURNAL

Histone H3 clipping in human embryonic stem cells: in pursuit of an epigenetic outcast

Liesbeth VossaertDieter DeforcePetra De SutterMaarten Dhaenens

Identification of histone H3 clipping activity in human embryonic stem cells

Liesbeth VossaertPaulien MeertEllen ScheerlinckPieter GlibertNadine Van RoyBjörn HeindryckxPetra De SutterMaarten DhaenensDieter Deforce

A1 Journal Article in STEM CELL RESEARCH

Illumina sequencing of 15 deafness genes using fragmented amplicons

Filip Van NieuwerburghSarah De KeulenaerJoachim De SchrijverJo VandesompeleWim Van CriekingePaul CouckeDieter Deforce

A2 Journal Article in BMC RESEARCH NOTES

Immunoreactive proteins of Brachyspira hyodysenteriae in pigs

Nele De PauwKatleen Van SteendamLien Vande MaeleMaxime MahuFilip BoyenAn MartelFreddy HaesebrouckDieter DeforceFrank Pasmans

In vitro inhibition of the transcription factor NF-κB and cyclooxygenase by bamboo extracts

Laura Van HoyweghenKarolien De BosscherGuy HaegemanDieter DeforceArne Heyerick

A1 Journal Article in PHYTOTHERAPY RESEARCH

Inhibition of TGFß signaling supports embryonic stem cell derivation and the ground state of pluripotency in mouse

Sabitri GhimireBjörn HeindryckxJitesh NeupaneDieter DeforceTom DerooPetra De Sutter

More than meets the eye : from fetal microchimerism to forensic applications

Trees LepezDieter Deforce

Mutation-free baby born from a mitochondrial encephalopathy, lactic acidosis and stroke-like syndrome carrier after blastocyst trophectoderm preimplantation genetic diagnosis

Björn HeindryckxJitesh NeupaneMado VandewoestyneCHRISTODOULOS CHRISTODOULOUYens JackersJan GerrisEtienne Van den AbbeelRudy Van CosterDieter DeforcePetra De Sutter

A1 Journal Article in MITOCHONDRION

My-Forensic-Loci-queries (MyFLq) framework for analysis of forensic STR data generated by massive parallel sequencing

Christophe Van NesteMado VandewoestyneWim Van CriekingeDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Neutrophil elastase in the capacity of the 'H2A-specific protease'

Maarten DhaenensPieter GlibertStijn LambrechtLiesbeth VossaertKatleen Van SteendamDirk ElewautDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

New and selective methods for the detection of phytoestrogens in biological matrices

Ciska WynsDieter DeforceMarc Bracke

Passive immunization to reduce Campylobacter jejuni colonization and transmission in broiler chickens

David HermansKatleen Van SteendamElin VerbruggheMarc VerlindenAn MartelTomasz SeliwiorstowMarc HeyndrickxFreddy HaesebrouckLieven De ZutterDieter Deforce et al.

A1 Journal Article in VETERINARY RESEARCH

Perfrin, a novel bacteriocin associated with netB positive Clostridium perfringens strains from broilers with necrotic eneteritis

Leen TimbermontLina De SmetFilip Van NieuwerburghValeria R PareiraGonzalez Van DriesscheFreddy HaesebrouckRichard DucatelleJohn PrescottDieter DeforceBart Devreese et al.

A1 Journal Article in VETERINARY RESEARCH

Presence and analysis of plasmids in human and animal associated Arcobacter species

Laid DouidahLieven De ZutterFilip Van NieuwerburghDieter DeforceHanne IngmerOlivier VandenbergAnne-Marie Van Den AbeeleKurt Houf

A1 Journal Article in PLOS ONE

Quantitative proteomics to characterize specific histone H2A proteolysis in chronic lymphocytic leukemia and the myeloid THP-1 cell line

Pieter GlibertLiesbeth VossaertKatleen Van SteendamStijn LambrechtFilip Van NieuwerburghFritz OffnerThomas KippsMaarten DhaenensDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Refined candidate region for F4ab/ac enterotoxigenic Escherichia coli susceptibility situated proximal to MUC13 in pigs

Tiphanie GoetstouwersMario Van PouckeWouter CoppietersUt Nguyen VanVesna MelkebeekAnnelies CoddensKatleen Van SteendamDieter DeforceEric CoxLuc Peelman

A1 Journal Article in PLOS ONE

Retrospective study of the impact of miniSTRs on forensic DNA profiling of touch DNA samples

Filip Van NieuwerburghDavid Van HoofstatChristophe Van NesteDieter Deforce

A1 Journal Article in SCIENCE & JUSTICE

Safety assessment of the butyrate-producing Butyricicoccus pullicaecorum strain 25-3T, a potential probiotic for patients with inflammatory bowel disease, based on oral toxicity tests and whole genome sequencing

Marjan SteppeFilip Van NieuwerburghGriet VercauterenFilip BoyenVenessa EeckhautDieter DeforceFreddy HaesebrouckRichard DucatelleFilip Van Immerseel

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

ScsA as a major driver for increased survival of Salmonella during a stress response

Elin VerbruggheMaarten DhaenensBregje LeymanFilip BoyenNeil ShearerAlexander Van ParysRoel HaesendonckWim BertHerman FavoreelDieter Deforce et al.

Selective serotonin reuptake inhibitors as a novel class of immunosuppressants

Veerle GobinKatleen Van SteendamDamiaan DenysDieter Deforce

A1 Journal Article in INTERNATIONAL IMMUNOPHARMACOLOGY

Small molecules, big effects? : the use of small molecules during human embryo development and human embryonic stem cell derivation

Margot Van der JeughtPetra De SutterDieter Deforce

Species identification from hair by means of spectral library searches

Katleen Van SteendamOdile De WulfMaarten DhaenensDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF LEGAL MEDICINE

The BCESM genomic region contains a regulator involved in quorum sensing and persistence in Burkholderia cenocepacia J2315

Heleen Van AckerEvelien De CanckFilip Van NieuwerburghAndrea SassDieter DeforceHans NelisTom Coenye

A1 Journal Article in FUTURE MICROBIOLOGY

The effects of positioning, reason for screening and the referring veterinarian on prevalence estimates of canine hip dysplasia

Bart BroeckxGeert VerhoevenFrank CoopmanWim Van HaeringenTim BosmansIngrid GielenSara HenckensJimmy SaundersHenri van BreeBernadette Van Ryssen et al.

A1 Journal Article in VETERINARY JOURNAL

The quest for true post-translational protein modifications through label-based quantitative mass spectrometry

Pieter GlibertDieter DeforceMaarten Dhaenens

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

Margot Van der JeughtBjörn HeindryckxThomas O'LearyGalbha DuggalSabitri GhimireSylvie LiermanNadine Van RoySusana Marina Chuva de Sousa LopesTom DerooDieter Deforce et al.

A1 Journal Article in HUMAN REPRODUCTION

Variation in 12 porcine genes involved in the carbohydrate moiety assembly of glycosphingolipids does not account for differential binding of F4 Escherichia coli and their fimbriae

Tiphanie GoetstouwersMario Van PouckeAnnelies CoddensUt Nguyen VanVesna MelkebeekDieter DeforceEric CoxLuc Peelman

A1 Journal Article in BMC GENETICS

iTRAQ as a method for optimization : enhancing peptide recovery after gel fractionation

Pieter GlibertKatleen Van SteendamMaarten DhaenensDieter Deforce

A1 Journal Article in PROTEOMICS

2013

A novel dictionary based computer vision method for the detection of cell nuclei

Jonas De VylderJan AeltermanTrees LepezMado VandewoestyneKoen DouterloigneDieter DeforceWilfried Philips

A1 Journal Article in PLOS ONE

An innovative integrated approach based on DNA walking to identify unauthorized GMOs

Marie-Alice FraiturePhilippe HermanIsabel TaverniersMarc De LooseDieter DeforceNancy Roosens

Ancient dispersal of the human fungal pathogen Cryptococcus gattii from the Amazon rainforest

Ferry HagenPaulo C CeresiniItzhack PolacheckHansong MaFilip Van NieuwerburghToni GabaldónSarah KaganE Rhiannon PursallHans L HoogveldLeo JJ van Iersel et al.

A1 Journal Article in PLOS ONE

Bioavailability of hop-derived bitter acids : key factors for the health-beneficial properties of beer

Ko CattoorDieter Deforce

Caspase-14-deficient mice are more prone to the development of parakeratosis

Esther HosteGeertrui DeneckerBarbara GilbertFilip Van NieuwerburghLeslie van der FitsBob AsselberghRiet De RyckeJean-Pierre HachemDieter DeforceErrol P Prens et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cytotoxic activity of Laserpitium latifolium L. extract and its daucane and phenylpropanoid constituents

Višnja PopovićArne HeyerickSilvana PetrovićSerge Van CalenberghIzet KaralicMarjan NiketićDieter Deforce

A1 Journal Article in RECORDS OF NATURAL PRODUCTS

Differential transcriptome analysis of glandular and filamentous trichomes in Artemisia annua

Sandra SoetaertChristophe Van NesteMado VandewoestyneSteven R HeadAlain GoossensFilip Van NieuwerburghDieter Deforce

A1 Journal Article in BMC PLANT BIOLOGY

Differentiation of F4 receptor profiles in pigs based on their mucin 4 polymorphism, responsiveness to oral F4 immunization and in vitro binding of F4 to villi

Ut Nguyen VanTiphanie GoetstouwersAnnelies CoddensMario Van PouckeLuc PeelmanDieter DeforceVesna MelkebeekEric Cox

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Fetal microchimeric cells in autoimmune thyroid diseases: harmful, beneficial or innocent for the thyroid gland?

Trees LepezMado VandewoestyneDieter Deforce

A2 Journal Article in CHIMERISM

Fluoxetine reduces murine graft-versus-host disease by induction of T cell immunosuppression

Veerle GobinKatleen Van SteendamSabine FeveryKelly TillemanAn D BilliauDamiaan DenysDieter Deforce

A1 Journal Article in JOURNAL OF NEUROIMMUNE PHARMACOLOGY

Genome sequence of Helicobacter heilmannii sensu stricto ASB1 isolated from the gastric mucosa of a kitten with severe gastritis

Annemieke SmetFilip Van NieuwerburghJesica LedesmaBram FlahouDieter DeforceRichard DucatelleFreddy Haesebrouck

A4 Journal Article in GENOME ANNOUNCEMENTS

Genome-wide association study of obsessive-compulsive disorder

SE StewartD YuJM ScharfBM NealeJA FagernessCA MathewsPD ArnoldPD EvansER GamazonL Osiecki et al.

A1 Journal Article in MOLECULAR PSYCHIATRY

Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential

Galbha DuggalBjörn HeindryckxSharat WarrierThomas O'LearyMargot Van der JeughtSylvie LiermanLiesbeth VossaertTom DerooDieter DeforceSusana Marina Chuva de Sousa Lopes et al.

A1 Journal Article in STEM CELLS AND DEVELOPMENT

Laser capture microdissection: should an ultraviolet or infrared laser be used?

Mado VandewoestyneKaren GoossensChristian BurvenichAnn Van SoomLuc PeelmanDieter Deforce

A1 Journal Article in ANALYTICAL BIOCHEMISTRY

Mass spectrometry-based proteomics as a tool to identify biological matrices in forensic science

Katleen Van SteendamMarlies De CeuleneerMaarten DhaenensDavid Van HoofstatDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Metabolism of hop-derived bitter acids

Ko CattoorMichael DreselLies De BockKoen BousseryJan Van BocxlaerJean Paul RemonDenis De KeukeleireDieter DeforceThomas HofmannArne Heyerick

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Nuclear transfer can prevent mitochondrial DNA carry-over without compromising embryonic development potential in mice

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxTom DerooYuechao LuSabitri GhimireSylvie LiermanChen QianDieter DeforcePetra De Sutter

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

Lea K DavisDongmei YuClare L KeenanEric R GamazonAnuar I KonkashbaevEske M DerksBenjamin M NealeJian YangS Hong LeePatrick Evans et al.

A1 Journal Article in PLOS GENETICS

PiTRAQ, a strategy to simultaneously correlate protein expression and phosphorylation stoichiometry between different samples: evaluation on different mass spectrometers

Pieter GlibertMaarten DhaenensPaulien MeertNiklaas ColaertFilip Van NieuwerburghLennart MartensDieter Deforce

Predominant mucosal expression of 5-HT4(+h) receptor splice variants in pig stomach and colon

Evelien PriemJoris H De MaeyerMado VandewoestyneDieter DeforceRomain Lefebvre

A1 Journal Article in WORLD JOURNAL OF GASTROENTEROLOGY

Presence and potential of cell free DNA in different types of forensic samples

Mado VandewoestyneDavid Van HoofstatAimee FranssenFilip Van NieuwerburghDieter Deforce

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Prevalence of genetic disorders in dogs from Belgium, the Netherlands and Germany

Bart BroeckxFrank CoopmanGeert VerhoevenWim Van HaeringenTim BosmansIngrid GielenJimmy SaundersHenri van BreeFilip Van NieuwerburghBernadette Van Ryssen et al.

Proteomic analysis of the excretory-secretory products from larval stages of Ascaris suum reveals high abundance of glycosyl hydrolases

Tao WangKatleen Van SteendamMaarten DhaenensJohnny VlaminckDieter DeforceAaron R JexRobin B GasserPeter Geldhof

A1 Journal Article in PLOS NEGLECTED TROPICAL DISEASES

Quantification of IFNγ- and IL17-producing cells after stimulation with citrullinated proteins in healthy subjects and RA patients

Katleen Van SteendamMarlies De CeuleneerKelly TillemanDirk ElewautFilip De KeyserDieter Deforce

A1 Journal Article in RHEUMATOLOGY INTERNATIONAL

Reference loci for RT-qPCR analysis of differentiating human embryonic stem cells

Liesbeth VossaertThomas O'LearyChristophe Van NesteBjörn HeindryckxJo VandesompelePetra De SutterDieter Deforce

A1 Journal Article in BMC MOLECULAR BIOLOGY

Regulation of inositol 1,4,5-trisphosphate receptor during human oocyte maturation and fertilization

Dimitra NikiforakiLiesbeth VossaertFrauke Vanden MeerschautChen QianYuechao LuJ ParysWinnok De VosDieter DeforceTom DerooEtienne Van den Abbeel et al.

Sesquiterpene lactones from the extracts of two Balkan endemic Laserpitium species and their cytotoxic activity

Visnja PopovicArne HeyerickSilvana PetrovićSerge Van CalenberghIzet KaralićMarjan NiketićDieter Deforce

A1 Journal Article in PHYTOCHEMISTRY

TRAPID : an efficient online tool for the functional and comparative analysis of de novo RNA-Seq transcriptomes

Michiel Van BelSebastian ProostChristophe Van NesteDieter DeforceYves Van de PeerKlaas Vandepoele

A1 Journal Article in GENOME BIOLOGY

The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4-and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation

Margot Van der JeughtThomas O'LearySabitri GhimireSylvie LiermanGalbha DuggalKaren VersierenDieter DeforceSusana Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter

A1 Journal Article in STEM CELLS AND DEVELOPMENT

The integration of the detection of systemic sclerosis-associated antibodies in a routine laboratory setting: comparison of different strategies

Carolien BonroyVanessa SmithKatleen Van SteendamJens Van PraetDieter DeforceKatrien DevreeseFilip De Keyser

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

The novel 'Candidatus Amphibiichlamydia ranarum' is highly prevalent in invasive exotic bullfrogs (Lithobates catesbeianus)

An MartelConnie AdriaensenMojdeh Sharifian FardMado VandewoestyneDieter DeforceHerman FavoreelKarolien BergenAdriana Marieke van der SluijsSander DevisscherTim Adriaens et al.

A1 Journal Article in ENVIRONMENTAL MICROBIOLOGY REPORTS

The prevalence of nine genetic disorders in a dog population from Belgium, the Netherlands and Germany

Bart BroeckxFrank CoopmanGeert VerhoevenWim Van HaeringenLeanne van de GoorTim BosmansIngrid GielenJimmy SaundersSandra SoetaertHenri van Bree et al.

A1 Journal Article in PLOS ONE

Trichomes, the key to an increased production of artemisinin in Artemisia annua

Sandra SoetaertDieter DeforceAlain GoossensFilip Van Nieuwerburgh

2012

A novel dictionary based detection method for cell nuclei

Jonas De VylderJan AeltermanDanilo BabinMado VandewoestyneTrees LepezDieter DeforceWilfried Philips

Absorption, translocation and metabolism of metamitron in Chenopodium album

Jonas AperEls MechantBaruch RubinArne HeyerickGert CallebautSven MangelinckxDieter DeforceNorbert De KimpeRobert BulckeDirk Reheul

A1 Journal Article in PEST MANAGEMENT SCIENCE

Assessment of microbial diversity in biofilms recovered from endotracheal tubes using culture dependent and independent approaches

Ilse VandecandelaereNele MatthijsFilip Van NieuwerburghDieter DeforcePETER VOSTERSLiesbet De BusHans NelisPieter DepuydtTom Coenye

A1 Journal Article in PLOS ONE

Batrachochytrium dendrobatidis zoospore secretions rapidly disturb intercellular junctions in frog skin

Melanie BrutynKatharina D'HerdeMaarten DhaenensPascale Van RooijElin VerbruggheAlex D HyattSiska CroubelsDieter DeforceRichard DucatelleFreddy Haesebrouck et al.

A1 Journal Article in FUNGAL GENETICS AND BIOLOGY

Catechol-O-methyltranferase gene expression is associated with response to citalopram in obsessive-compulsive disorder

Nienke CC VulinkHerman GM WestenbergFilip Van NieuwerburghDieter DeforceSjoerd BAHA FluitmanJantien SC MeinardiDamiaan Denys

A1 Journal Article in INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE

Cell nuclei detection using globally optimal active contours with shape prior

Jonas De VylderJan AeltermanMado VandewoestyneTrees LepezDieter DeforceWilfried Philips

Characterization of citrullination in the context of rheumatoid arthritis

Marlies De CeuleneerDieter Deforce

Development and validation of an LC-MS/MS method for the simultaneous determination of deoxynivalenol, zearalenone, T-2 toxin and some masked metabolites in different cereals and cereal-derived food

Marthe De BoevreJosé Diana Di MavunguPeter MaeneKris AudenaertDieter DeforceGeert HaesaertMia EeckhoutAlfons CallebautFranz BerthillerCarlos Van Peteghem et al.

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

Development of a dedicated peptide tandem mass spectral library for conservation science

Wim FremoutMaarten DhaenensSteven SaverwynsJana SanyovaPeter VandenabeeleDieter DeforceLuc Moens

A1 Journal Article in ANALYTICA CHIMICA ACTA

Evaluation of a strategy for parallel protein phosphorylation and expression analysis

Pieter GlibertMaarten DhaenensPaulien MeertNiklaas ColaertFilip Van NieuwerburghLennart MartensDieter Deforce

Evaluation of three DNA extraction protocols for forensic STR typing after laser capture microdissection

Mado VandewoestyneFilip Van NieuwerburghDavid Van HoofstatDieter Deforce

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Fetal microchimeric cells in blood and thyroid glands of women with an autoimmune thyroid disease

Trees LepezMado VandewoestyneDieter Deforce

A2 Journal Article in CHIMERISM

Fetal microchimeric cells in the blood of women with an autoimmune thyroid disease

Trees LepezMado VandewoestyneFilip Van NieuwerburghKris PoppeBrigit VelkeniersDieter Deforce

Fluorescence imaging of mitochondria in cultured skin fibroblasts: a useful method for detection of oxidative phosphorylation defects

Boel De PaepeJoél SmetArnaud VanlanderSara SenecaWilly LissensLinda De MeirleirMado VandewoestyneDieter DeforceRichard J RodenburgRudy Van Coster

A1 Journal Article in PEDIATRIC RESEARCH

Fluoroenzymeimmunoassay to detect systemic sclerosis-associated antibodies : diagnostic performance and correlation with conventional techniques

Carolien BonroyVanessa SmithKatleen Van SteendamJens Van PraetDieter DeforceKatrien DevreeseFilip De Keyser

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Forensic STR analysis using massive parallel sequencing

Christophe Van NesteFilip Van NieuwerburghDavid Van HoofstatDieter Deforce

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Illumina mate-paired DNA sequencing-library preparation using Cre-Lox recombination

Filip Van NieuwerburghRyan C ThompsonJessica LedesmaDieter DeforceTerry GaasterlandPhillip OrdoukhanianSteven R Head

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Immunization with the immunodominant Helicobacter suis urease subunit B induces partial protection against H. suis infection in a mouse model

Miet VermooteKatleen Van SteendamBram FlahouAnnemieke SmetFrank PasmansPieter GlibertRichard DucatelleDieter DeforceFreddy Haesebrouck

A1 Journal Article in VETERINARY RESEARCH

Immunoproteomics of Helicobacter suis and protective efficacy of a subunit vaccine in a mouse model

Miet VermooteKatleen Van SteendamBram FlahouFrank PasmansRichard DucatelleDieter DeforceFreddy Haesebrouck

In vivo relevance of citrullinated proteins and the challenges in their detection

Marlies De CeuleneerKatleen Van SteendamMaarten DhaenensDieter Deforce

A1 Journal Article in PROTEOMICS

Influence of hESC derivation conditions on germ cell differentiation potential

Galbha DuggalBjörn HeindryckxThomas O'LearySylvie LiermanDieter DeforceSusana Chuva de Sousa LopesPetra De Sutter

Isolation of disseminated neuroblastoma cells from bone marrow aspirates for pretreatment risk assessment by array comparative genomic hybridization

Mado VandewoestyneCandy KumpsKatrien SwertsBjörn MentenTim LammensJan PhilippéKatleen De PreterGenevieve LaureysNadine Van RoyFranki Speleman et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Laser capture microdissection in forensics

Mado VandewoestyneDavid Van HoofstatFilip Van NieuwerburghDieter Deforce

Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform

Sarah De KeulenaerJan HellemansSteve LefeverJean-Pierre RenardJoachim De SchrijverHendrik Van de VoordeMohammad Amin TabatabaiefarFilip Van NieuwerburghDaisy FlamezFilip Pattyn et al.

A1 Journal Article in BMC MEDICAL GENOMICS

Optimization and diagnostic performance of a single multiparameter lineblot in the serological workup of systemic sclerosis

Carolien BonroyJens Van PraetVanessa SmithKatleen Van SteendamT MimoriEllen DeschepperDieter DeforceKatrien DevreeseFilip De Keyser

A1 Journal Article in JOURNAL OF IMMUNOLOGICAL METHODS

Perfrin, a novel bacteriocin from a necrotic enteritis associated Clostridium perfringens strain

Leen TimbermontSofie GeeraertsLina De SmetFilip Van NieuwerburghValeria R ParreiraGonzalez Van DriesscheFreddy HaesebrouckRichard DucatelleJohn PrescottDieter Deforce et al.

Phenolic composition and in vitro bioactivities of 12 morphologically heterogeneous bamboo species

Laura Van HoyweghenDieter DeforceMarc Bracke

Phenolic compounds and anti-oxidant capacity of twelve morphologically heterogeneous bamboo species

Laura Van HoyweghenThomas De BeerDieter DeforceArne Heyerick

A1 Journal Article in PHYTOCHEMICAL ANALYSIS

Poor correlation between polar bodies and blastomere mutation load in a patient with m.3243A>G tRNALeu(UUR) point mutation

Mado VandewoestyneBjörn HeindryckxStefanie De GheselleTrees LepezJitesh NeupaneJan GerrisRudy Van CosterPetra De SutterDieter Deforce

A1 Journal Article in MITOCHONDRION

Prenylated chalcone xanthohumol associates with histones in breast cancer cells: a novel target identified by a monoclonal antibody

Ciska WynsKatleen Van SteendamBarbara VanhoeckeDieter DeforceMarc BrackeArne Heyerick

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

Pronuclear transfer in mice yields minimal mitochondrial DNA carry-over

Mado VandewoestyneJitesh NeupaneBjörn HeindryckxSylvie LiermanDieter DeforcePetra De Sutter

Proteomic analysis of the excretory-secretory products of the larval stages of Ascaris suum

Tao WangKatleen Van SteendamMaarten DhaenensJohnny VlaminckDieter DeforceAaron JexRobin B GasserJozef VercruyssePeter Geldhof

Purification and characterization of Perfrin, a novel bacteriocin from a virulent Clostridium perfringens strain

Leen TimbermontLina De SmetAnouk LanckrietFilip Van NieuwerburghValeria R ParreiraGonzalez Van DriesscheFreddy HaesebrouckRichard DucatelleJohn PrescottDieter Deforce et al.

Quantification of citrullination by means of skewed isotope distribution pattern

Marlies De CeuleneerKatleen Van SteendamMaarten DhaenensDirk ElewautDieter Deforce

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Relation between the FBN2 haplotype and phenotypical hip dysplasia

Bart BroeckxFrank CoopmanGeert VerhoevenTim BosmansAnn CC CrielIngrid GielenJimmy SaundersSandra SoetaertHenri van BreeWim Van Haeringen et al.

Reliability of pre-implantation genetic diagnosis in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuChen QianDieter DeforcePetra De Sutter

Reliability of pre-implantation genetic diagnosis in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuSylvie LiermanChen QianDieter DeforcePetra De Sutter

Serotonin reuptake inhibitors as immunomodulators: a proof-of-concept

Veerle GobinKatleen Van SteendamSabine FeveryKelly TillemanAn BilliauDamiaan DenysDieter Deforce

T-2 toxin induced Salmonella Typhimurium intoxication results in decreased Salmonella numbers in the cecum contents of pigs, despite marked effects on Salmonella-host cell interactions

Elin VerbruggheVirginie VandenbrouckeMaarten DhaenensNeil ShearerJoline GoossensSarah De SaegerMia EeckhoutKatharina D'HerdeArthur ThompsonDieter Deforce et al.

A1 Journal Article in VETERINARY RESEARCH

Targeting aminopeptidase N, a newly identified receptor for F4ac fimbriae, enhances the intestinal mucosal immune response

Vesna MelkebeekK RasschaertPhilippe BellotK TillemanHerman FavoreelDieter DeforceBruno De GeestBruno GoddeerisEric Cox

A1 Journal Article in MUCOSAL IMMUNOLOGY

The TGFβ pathway plays a pivotal role in early embryo lineage segregation

Margot Van der JeughtSabitri GhimireThomas O'LearySylvie LiermanDieter DeforceSusana Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter

Tracking the progression of the human inner cell mass during embryonic stem cell derivation

Thomas O'LearyBjörn HeindryckxSylvie LiermanDavid van BruggenJelle J GoemanMado VandewoestyneDieter DeforceSusana M Chuva de Sousa LopesPetra De Sutter

A1 Journal Article in NATURE BIOTECHNOLOGY

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

Margot Van der JeughtThomas O'LearySylvie LiermanDieter DeforceSusana Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter

Variations in the exome of the LNCaP prostate cancer cell line

Lien SpansZeynep Kalender AtakFilip Van NieuwerburghDieter DeforceEvelyne LerutStein AertsFrank Claessens

A1 Journal Article in PROSTATE

2011

Antihypertensive effect of insect cells: in vitro and in vivo evaluation

Dorien StaljanssensJohn Van CampGriet HerregodsMaarten DhaenensDieter DeforceJohan Van de VoordeGuy Smagghe

A1 Journal Article in PEPTIDES

Bioavailability of hop-derived iso-α-acids and reduced derivatives

Ko CattoorJean Paul RemonKoen BousseryJan Van BocxlaerMarc BrackeDenis De KeukeleireDieter DeforceArne Heyerick

A1 Journal Article in FOOD & FUNCTION

Calcium releasing ability of human sperm with deficient oocyte activation capacity

Dimitra NikiforakiFrauke Vanden MeerschautChen QianDieter DeforceEsther Van den AbbeelK CowardJ ParringtonLuc LeybaertBjörn HeindryckxPetra De Sutter

Culture optimisation to direct differentiation of human embryonic stem cells into primordial germ cells

Galbha DuggalBjörn HeindryckxThomas O'LearySylvie LiermanDieter DeforceS Chuva de Sousa LopesPetra De Sutter

Development and validation of an LC-MS/MS-method for the simultaneous determination of deoxynivalenol, zearalenone, T2-toxin and their masked forms in different cereals and cereal based food

Marthe De BoevreJosé Diana Di MavunguAleksandrs VersilovskisPeter MaeneKris AudenaertDieter DeforceAlfons CallebautGeert HaesaertMia EeckhoutCarlos Van Peteghem et al.

Development and validation of an LC-MS/MS-method for the simultaneous determination of deoxynivalenol, zearalenone, T2-toxin and their masked forms in different cereals and cereal based food.

Marthe De BoevreJosé Diana Di MavunguAleksandrs VersilovskisPeter MaeneKris AudenaertDieter DeforceAlfons CallebautGeert HaesaertMia EeckhoutCarlos Van Peteghem et al.

Dissection of the phytohormonal regulation of trichome formation and biosynthesis of the antimalarial compound artemisinin in Artemisia annua plants

Lies MaesFilip Van NieuwerburghYansheng ZhangDarwin W ReedJacob PollierSofie Vande CasteeleDirk InzéPatrick S CovelloDieter DeforceAlain Goossens

A1 Journal Article in NEW PHYTOLOGIST

Dysregulated adaptive immunity in two models of immune mediated inflammatory diseases: rheumatoid arthritis and systemic sclerosis

Katleen Van SteendamDieter DeforceFilip De KeyserDirk Elewaut

Fetal microchimeric cells in blood of women with an autoimmune thyroid disease

Trees LepezMado VandewoestyneShahid HussainFilip Van NieuwerburghKris PoppeBrigitte VelkeniersJean KaufmanDieter Deforce

A1 Journal Article in PLOS ONE

From dysregulated protein expression to histone clipping: the virtue of mass spectrometry: a proteomics tale of serendipity

Maarten DhaenensDieter Deforce

GDF15, a distinct TGFb family member, is differentially regulated in spondyloarthritides compared to other rheumatic diseases

Stijn LambrechtJulie CoudenysFilip De KeyserAugust VerbruggenDieter DeforceDirk Elewaut

Genomic applications of laser capture microdissection

Mado VandewoestyneDieter DeforcePetra De Sutter

Immunizing pigs with Ascaris suum haemoglobin increases the inflammatory response in the liver but fails to induce a protective immunity

Johnny VlaminckM Martinez-ValladaresSylvia DewildeLuc MoensKatrien TillemanDieter DeforceJ UrbanEdwin ClaereboutJozef VercruyssePeter Geldhof

A1 Journal Article in PARASITE IMMUNOLOGY

JC-1-based fluorescence to evaluate oxidative phosphorylation defects generates both qualitative and quantitative information

Boel De PaepeJoél SmetSara SenecaWilly LissensLinda De MeirleirMado VandewoestyneDieter DeforceSilke MusscheEmmanuel ScalaisRudy Van Coster

Laser capture microdissection for forensic DNA analysis

Mado VandewoestyneDieter Deforce

A2 Journal Article in FORENSIC SCIENCE INTERNATIONAL. GENETICS SUPPLEMENT SERIES

Laser microdissection for the assessment of the clonal relationship between chronic lymphocytic leukemia/small lymphocytic lymphoma and proliferating B cells within lymph node pseudofollicles

Mado VandewoestyneValerie PedeKathleen LambeinMaarten DhaenensFritz OffnerMarleen PraetJan PhilippéThomas J KippsDieter Deforce

A1 Journal Article in LEUKEMIA

Masked Fusarium mycotoxins: results of a one-year survey in Flanders

Marthe De BoevreJosé Diana Di MavunguPeter MaeneKris AudenaertDieter DeforceGeert HaesaertMia EeckhoutCarlos Van PeteghemSarah De Saeger

Modification of citrulline residues with 2,3-butanedione facilitates their detection by liquid chromatography/mass spectrometry

Marlies De CeuleneerVanessa De WitKatleen Van SteendamFilip Van NieuwerburghKelly TillemanDieter Deforce

A1 Journal Article in RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Neutrophil elastase is the 'histone H2A-specific protease'

Pieter GlibertMaarten DhaenensStijn LambrechtDirk ElewautFritz OffnerTJ KippsDieter Deforce

Phospholipase Cβ1 as a possible oocyte factor responsible for successful oocyte activation and embryo development

Frauke Vanden MeerschautBjörn HeindryckxChen QianDieter DeforceLuc LeybaertPetra De Sutter

Polar body mutation load analysis in a patient with A3243G tRNALeu(UUR) point mutation

Mado VandewoestyneBjörn HeindryckxTrees LepezRudy Van CosterJan GerrisPetra De SutterDieter Deforce

A1 Journal Article in MITOCHONDRION

Practical tools to implement massive parallel pyrosequencing of PCR products in next generation molecular diagnostics

Kim De LeeneerJoachim De SchrijverLieven ClementMachteld BaetensSteve LefeverSarah De KeulenaerWim Van CriekingeDieter DeforceFilip Van NieuwerburghSofie Bekaert et al.

A1 Journal Article in PLOS ONE

Production of monoclonal antibodies against hop-derived (Humulus lupulus L.) prenylflavonoids and the development of immunoassays

Ciska WynsLara DeryckeBram SoenenSelin BolcaDieter DeforceMarc BrackeArne Heyerick

A1 Journal Article in TALANTA

Quantitative bias in Illumina TruSeq and a novel post amplification barcoding strategy for multiplexed DNA and small RNA deep sequencing

Filip Van NieuwerburghSandra SoetaertKatie PodshivalovaEileen Ay-Lin WangLana SchafferDieter DeforceDaniel R SalomonSteven R HeadPhillip Ordoukhanian

A1 Journal Article in PLOS ONE

Reduced levels of the TGFB family member GDF15 in spondyloarthritis versus other rheumatic diseases

Stijn LambrechtJulie CoudenysFilip De KeyserAugust VerbruggenDieter DeforceDirk Elewaut

Serotonin reuptake inhibitors selectively decrease proliferation and viability of activated T-cells

Veerle GobinKatleen Van SteendamDieter Deforce

Sources of DNA contamination and decontamination procedures in the forensic laboratory

Mado VandewoestyneDavid Van HoofstatSabine De GrooteNicky Van ThuyneSaskia HaerinckFilip Van NieuwerburghDieter Deforce

A2 Journal Article in INTERNATIONAL JOURNAL OF FORENSIC PRACTICE AND RESEARCH

Specific anti-nuclear antibodies in systemic sclerosis patients with and without skin involvement : an extended methodological approach

Jens Van PraetKatleen Van SteendamVanessa SmithGeorges De BruyneTsuneyo MimoriCarolien BonroyDirk ElewautDieter DeforceFilip De Keyser

A1 Journal Article in RHEUMATOLOGY

The influence of early embryo traits on human embryonic stem cell derivation efficiency

Thomas O'LearyBjörn HeindryckxSylvie LiermanMargot Van der JeughtBjörn MentenDieter DeforceMaria CornelissenSusana Chuva de Sousa LopesPetra De Sutter

A1 Journal Article in STEM CELLS AND DEVELOPMENT

The relevance of citrullinated vimentin in the production of antibodies against citrullinated proteins and the pathogenesis of rheumatoid arthritis

Katleen Van SteendamKelly TillemanDieter Deforce

A1 Journal Article in RHEUMATOLOGY

Transcriptome analysis of apical and sub-apical cells of Artemisia annua trichomes with next-generation-sequencing

Sandra SoetaertFilip Van NieuwerburghPeter BrodeliusAlain GoossensDieter Deforce

Usefulness of a novel serum proteome-derived index FI-PRO (fibrosis-protein) in the prediction of fibrosis in chronic hepatitis C

Kin Jip CheungKelly TillemanDieter DeforceIsabelle ColleChristophe MorenoThierry GustotHans Van Vlierberghe

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Whole genome sequence analysis of Helicobacter heilmannii

Annemieke SmetFilip Van NieuwerburghBram FlahouFrank PasmansDieter DeforceRichard DucatelleFreddy Haesebrouck

2010

An update: investigation of new analytical challenges for mycotoxin determination: masked mycotoxins

Marthe De BoevreJosé Diana Di MavunguPeter MaeneKris AudenaertDieter DeforceGeert HaesaertMia EeckhoutCarlos Van PeteghemSarah De Saeger

Analysing 454 amplicon resequencing experiments using the modular and database oriented Variant Identification Pipeline

Joachim De SchrijverKim De LeeneerSteve LefeverNick SabbeFilip PattynFilip Van NieuwerburghPaul CouckeDieter DeforceJo VandesompeleSofie Bekaert et al.

A1 Journal Article in BMC BIOINFORMATICS

Antioxidant flavone glycosides from the leaves of Fargesia robusta

Laura Van HoyweghenIzet KaralicSerge Van CalenberghDieter DeforceArne Heyerick

A1 Journal Article in JOURNAL OF NATURAL PRODUCTS

Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins

Katleen Van SteendamKelly TillemanMarlies De CeuleneerFilip De KeyserDirk ElewautDieter Deforce

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Complete nucleotide sequence of CTX-M-15-plasmids from clinical Escherichia coli isolates: insertional events of transposons and insertion sequences

Annemieke SmetFilip Van NieuwerburghTom VandekerckhoveAn MartelDieter DeforcePatrick ButayeFreddy Haesebrouck

A1 Journal Article in PLOS ONE

Compulsivity in mouse strains homologous with chromosomes 7p and 15q linked tot obsessive-compulsive disorder

Martien JH KasCigdem GelegenFilip Van NieuwerburghHerman GM WestenbergDieter DeforceDamiaan Denys

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Galectin-3-binding protein : a serological and histological assessment in accordance with hepatitis C-related liver fibrosis

Kin Jip CheungLouis LibbrechtKelly TillemanDieter DeforceIsabelle ColleHans Van Vlierberghe

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Influence of reaction medium during synthesis of Gantrez® AN 119 nanoparticles for oral vaccination

Katrien VandammeVesna MelkebeekEric CoxDieter DeforceJoke LenoirEls AdriaensChris VervaetJean Paul Remon

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Invariant natural killer T cells are natural regulators of murine spondylarthritis

Peggy JacquesKoen VenkenKatrien Van BenedenHamida HammadSylvie SeeuwsMichael DrennanDieter DeforceAugust VerbruggenMaria ApostolakiGeorge Kollias et al.

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Investigation of new analytical challenges for mycotoxin determination: masked mycotoxins

Marthe De BoevreJosé Diana Di MavunguPeter MaeneKris AudenaertDieter DeforceGeert HaesaertMia EeckhoutCarlos Van PeteghemSarah De Saeger

Laser capture microdissection in forensic research: a review

Mado VandewoestyneDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Laser microdissection in forensic sciences

Trees LepezMado VandewoestyneDieter Deforce

Masked mycotoxins: an emerging issue for food safety

Marthe De BoevreJosé Diana Di MavunguPeter MaeneKris AudenaertDieter DeforceGeert HaesaertMia EeckhoutCarlos Van PeteghemSarah De Saeger

Proteome characterization of human articular chondrocytes leads to novel insights in the function of small heat-shock proteins in chondrocyte homeostasis

Stijn LambrechtMaarten DhaenensKarl AlmqvistPeter VerdonkAugust VerbruggenDieter DeforceDirk Elewaut

A1 Journal Article in OSTEOARTHRITIS AND CARTILAGE

Quality analysis of salmon calcitonin in a polymeric bioadhesive pharmaceutical formulation: sample preparation optimization by DOE

Matthias D'HondtSylvia Van DorpeEls MehuysDieter DeforceBart De Spiegeleer

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Real-time PCR expression profiling of genes encoding potential virulence factors in Candida albicans biofilms: identification of model-dependent and -independent gene expression

Heleen NailisSoňa KucharíkováMarkéta ŘičicováPatrick Van DijckDieter DeforceHans NelisTom Coenye

A1 Journal Article in BMC MICROBIOLOGY

Reduced levels of the TGFB family member GDF15 in spondyloarthritis versus other rheumatic diseases

Stijn LambrechtFilip Van den BoschBert Vander CruyssenFilip De KeyserAugust VerbruggenDieter DeforceDirk Elewaut

Techniques to prevent mitochondrial mutation transmission

Björn HeindryckxMado VandewoestyneDieter DeforcePetra De Sutter

The Fibro7-score: a novel serum proteome- and clinical biochemistry-based predictive model for chronic hepatitis C liver fibrosis

Kin Jip CheungKelly TillemanDieter DeforceIsabelle ColleHans Van Vlierberghe

The role of the COMT Val158Met polymorphism in the phenotypic expression of obsessive-compulsive disorder

Hilga KaterbergDanielle C CathDamiaan AJP DenysPeter HeutinkAnnemiek PolmanFilip Van NieuwerburghDieter DeforceZoltán BochdanovitsAnton JLM van BalkomJohan A den Boer

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

The small heat-shock protein HSP27 shows a decreased abundance in OA and mediates IL-1B induced IL-6 secretion in human articular chondrocytes

Stijn LambrechtKarl AlmqvistPeter VerdonkAugust VerbruggenDieter DeforceDirk Elewaut

The small heat-shock protein HSP27 shows decreased expression in OA-chondrocytes and mediates IL-6 secretion in human articular chondrocytes

Stijn LambrechtKarl AlmqvistPeter VerdonkAugust VerbruggenDieter DeforceDirk Elewaut

Transcriptional response to fluconazole and amphotericin B in Candida albicans biofilms

Heleen NailisDavy VandenboschDieter DeforceHans NelisTom Coenye

A1 Journal Article in RESEARCH IN MICROBIOLOGY

Transport of hop bitter acids across intestinal Caco-2 cell monolayers

Ko CattoorMarc BrackeDieter DeforceDenis De KeukeleireArne Heyerick

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Tryptic peptide analysis of protein binders in works of art by liquid chromatography-tandem mass spectrometry

Wim FremoutMaarten DhaenensSteven SaverwynsJana SanyovaPeter VandenabeeleDieter DeforceLuc Moens

A1 Journal Article in ANALYTICA CHIMICA ACTA

Unbreakable codes in electrospun fibers : digitally encoded polymers to stop medicine counterfeiting

Chaobo HuangBart LucasChris VervaetKevin BraeckmansSerge Van CalenberghIzet KaralicMado VandewoestyneDieter DeforceJo DemeesterStefaan De Smedt

A1 Journal Article in ADVANCED MATERIALS

Unbreakable codes in electrospun fibers to stop medicine counterfeiting

Chaobo HuangBart LucasChris VervaetKevin BraeckmansSerge Van CalenberghIzet KaralicMado VandewoestyneDieter DeforceJo DemeesterStefaan De Smedt

2009

A proteomic approach applied on Rembrandt's ground layers

Wim FremoutMaarten DhaenensSteven SaverwynsSanyova JanaPeter VandenabeeleDieter DeforceLuc Moens

Application of a new anti-zearalenone monoclonal antibody in different immunoassay formats

Natalia BurmistrovaIrina GoryachevaEvgenia BasovaAnn-Sophie FrankiDirk ElewautKatrien Van BenedenDieter DeforceCarlos Van PeteghemSarah De Saeger

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Automatic detection of spermatozoa for laser capture microdissection

Mado VandewoestyneDavid Van HoofstatFilip Van NieuwerburghDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Citrullination breaks T-cell tolerance in patients with inflammatory arthritides and in healthy persons

Katleen Van SteendamMarlies De CeuleneerFilip De KeyserDirk ElewautKelly TillemanDieter Deforce

Comparative proteome analysis of porcine follicular fluid and serum reveals that excessive alpha(2)-macroglobulin in serum hampers successful expansion of cumulus-oocyte complexes

Jo BijttebierKelly TillemanMaarten DhaenensDieter DeforceAnn Van SoomDominiek Maes

A1 Journal Article in PROTEOMICS

Cutting Edge: The Chemokine Receptor CXCR3 Retains Invariant NK T Cells in the Thymus

Michael DrennanAnn-Sophie FrankiPieter DewintKatrien Van BenedenSylvie SeeuwsSerge van de PavertEmma ReillyGust VerbruggenThomas LaneReina Mebius et al.

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Dendritic cells from spondylarthritis-prone HLA-B27-transgenic rats display altered cytoskeletal dynamics, class II major histocompatibility complex expression, and viability

Maarten DhaenensIngrid FertSimon GlatignySaskia HaerinckCécile PoulainEmmanuel DonnadieuCécile Hacquard-BouderClaudine AndréDirk ElewautDieter Deforce et al.

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Differential expression of alpha B-crystallin and evidence of its role as a mediator of matrix gene expression in osteoarthritis

Stijn LambrechtAugust VerbruggenDirk ElewautDieter Deforce

A1 Journal Article in Arthritis and rheumatism

INFLUENCE OF SPERM CRYOPRESERVATION ON THE OOCYTE ACTIVATING FACTOR PLCAE

Elke HeytensJohn ParringtonStijn LambrechtClaire YoungKevin CowardReza SoleimaniJan GerrisMarc DhontDieter DeforcePetra De Sutter

Impact of allelic dropout on evidential value of forensic DNA profiles

Filip Van NieuwerburghEls GoetghebeurMado VandewoestyneDieter Deforce

A1 Journal Article in BIOINFORMATICS

Joint GC-MS and LC-MS platforms for comprehensive plant metabolomics: Repeatability and sample pre-treatment

Ruben T'KindtKris MorreelDieter DeforceWout BoerjanJan Van Bocxlaer

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Metabolite analysis of laser captured apical and subapical cells of Artemisia annua trichomes

Sandra SoetaertFilip Van NieuwerburghSofie Vande CasteeleMikael E OlssonMado VandewoestynePeter E BrodeliusAlain GoossensDieter Deforce

Monitoring ALS1 and ALS3 Gene Expression During In Vitro Candida albicans Biofilm Formation Under Continuous Flow Conditions

Heleen NailisRoosmarijn VandenbrouckeKelly TillemanDieter DeforceHans NelisTom Coenye

A1 Journal Article in MYCOPATHOLOGIA

Onderzoek rond nieuwe analytische uitdagingen voor de bepaling van mycotoxinen: gemaskeerde mycotoxinen

Marthe De BoevreJosé Diana Di MavunguPeter MaeneKris AudenaertDieter DeforceGeert HaesaertMia EeckhoutCarlos Van PeteghemSarah De Saeger

Phytohormonal regulation of gland formation and artemisinin biosynthesis in Artemisia annua

Filip Van NieuwerburghLies MaesSofie Vande CasteeleSandra SoetaertMarc Van MontaguDirk InzéDieter DeforceAlain Goossens

Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models

Sandra PeresonHans WilsGernot KleinbergerEileen McGowanMado VandewoestyneBianca Van BroeckGeert JorisIvy CuijtDieter DeforceMichael Hutton et al.

A1 Journal Article in Journal of Pathology

Proteomic study to identify factors in follicular fluid and/or serum involved in in vitro cumulus expansion of porcine oocytes

Jo BijttebierKelly TillemanDieter DeforceMaarten DhaenensAnn Van SoomDominiek Maes

RMNE probability of Forensic DNA profiles with allelic drop-out

Filip Van NieuwerburghEls GoetghebeurMado VandewoestyneDieter Deforce

A2 Journal Article in Forensic science international. Genetics

Reduced amounts and abnormal forms of phospholipase C zeta (PLC zeta) in spermatozoa from infertile men

Elke HeytensJ ParringtonK CowardC YoungSTEFANIE LAMBRECHTSY YoonRA FissoreR. HamerCM DeaneM Ruas et al.

A1 Journal Article in HUMAN REPRODUCTION

Response to serotonin reuptake inhibitors in OCD is not influenced by common CYP2D6 polymorphisms

Filip Van NieuwerburghDamiaan DenysHerman WestenbergDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE

Specific modification of protein-bound citrulline residues facilitates their detection

Marlies De CeuleneerKelly TillemanKatleen Van SteendamDieter Deforce

Specific modification of protein-bound citrulline residues facilitates their detection

Marlies De CeuleneerKelly TillemanKatleen Van SteendamDieter Deforce

Suspension fluorescence in situ hybridization (S-FISH) combined with automatic detection and laser microdissection for STR profiling of male cells in male/female mixtures

Mado VandewoestyneDavid Van HoofstatFilip Van NieuwerburghDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF LEGAL MEDICINE

T cell reactivity against citrullinated proteins does not differ between healthy persons and patients with inflammatory arthritis

Katleen Van SteendamMarlies De CeuleneerFilip De KeyserDirk ElewautKelly TillemanDieter Deforce

The HCV serum proteome: a search for fibrosis protein markers

Kin Jip CheungKelly TillemanDieter DeforceIsabelle ColleHans Van Vlierberghe

A1 Journal Article in JOURNAL OF VIRAL HEPATITIS

The small heat-shock protein HSP27 shows a decreased abundance in OA and mediates IL-1B induced IL-6 secretion in human articular chondrocytes

Stijn LambrechtAugust VerbruggenDieter DeforceDirk Elewaut

2008

A new approach for defining the relative contribution of co-migrating proteins to spot intensity in 2D-PAGE

Maarten DhaenensSofie VandecasteeleDieter Deforce

A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis

Pieter DewintValerie GossyeKarolien De BosscherWim Vanden BergheKatrien Van BenedenDieter DeforceSerge Van CalenberghU MULLER-LADNERBert Vander CruyssenAugust Verbruggen et al.

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Analysis of oligonucleotides using capillary zone electrophoresis and electrospray mass spectrometry

An WillemsDieter DeforceJan Van Bocxlaer

Bookchapter in Capillary electrophoresis

Automatic detection of spermatozoa for laser capture microdissection

Mado VandewoestyneDavid Van HoofstatFilip Van NieuwerburghDieter Deforce

Dendritic Cells from Spondyloarthritis-prone HLA-B27 Transgenic Rat Display Altered Cytoskeletal Dynamics, MHC Class II Expression, and Viability.

Maarten DhaenensIngrid FertSimon GlatignySaskia HaerinckCéline PoulainEmanuel DonnadieuCécile Hacquard-BouderClaudine AndréDirk ElewautDieter Deforce et al.

Dendritic Cells from Spondyloarthritis-prone HLA-B27 Transgenic Rat Display Altered Cytoskeletal Dynamics, MHC Class II Expression, and Viability.

Maarten DhaenensFert IngridGlatigny SimonSaskia HaerinckCeline PoulainEmanuel DonnadieuCéline Hacquard-BouderClaudine AndréDirk ElewautDieter Deforce et al.

Differential proteome analysis of normal and osteoarthritic chondrocytes reveals distortion of vimentin network in osteoarthritis

Stijn LambrechtGert VerbruggenPETER VERDONKDirk ElewautDieter Deforce

A1 Journal Article in OSTEOARTHRITIS AND CARTILAGE

Do all anti-citrullinated protein/peptide antibody tests measure the same? Evaluation of discrepancy between anti-citrullinated protein/peptide antibody tests in patients with and without rheumatoid arthritis

Bert Vander CruyssenL NOGUEIRAJens Van PraetDieter DeforceDirk ElewautG SERREFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Evaluation of hydrophilic interaction chromatography versus reversed-phase chromatography in a plant metabolomics perspective

Ruben T'KindtMichael StormeDieter DeforceJan Van Bocxlaer

A1 Journal Article in JOURNAL OF SEPARATION SCIENCE

Evidence for Altered Cytoskeleton Mobilization Pathway in Splenic Dendritic Cells (DC) from HLA-B27/human b2 microglobulin Transgenic Rats (B27-rats)

Maarten DhaenensIngrid FertSimon GlatignySaskia HaerinckCeline Hacquard-BouderClaudine AndréDirk ElewautDieter DeforceMaxime Breban

FILA-1127 Transgenic rat OX62(+) DCs exhibit multiple cellular deficiencies and the tolerigenic CD4(-) subset suffers reduced viability

M DHAENENSI FRETS GLATIGNYS HAERINCKC HACQUARD-BOUDERC ANDREDirk ElewautDieter DeforceM BREBAN

First evidence of disturbed expression of the oocyte-activating factor PLCzeta in globozoospermic men

Elke HeytensJohn ParringtonStijn LambrechtClaire YoungKevin CowardClaude CuvelierJan GerrisMarc DhontDieter DeforcePetra De Sutter

Gene expression profiling to identify microvascular changes in Alzheimer's disease mouse models

Sandra PeresonMado VandewoestyneBianca Van BroeckIvy CuijtEdith PeetersChantal CeuterickEileen McGowanMathias JuckerChristine Van BroeckhovenDieter Deforce et al.

HLA-B27 transgenic rat OX62+DCs exhibit multiple cellular deficiencies and the tolerigenic CD4-subset suffers reduced viability

M DHAENEUSI FERTS GLATIGNYS HAERINCKC HACQUARD-BOUDERC ANDREDirk ElewautDieter DeforceM BREHAN

Identification and possible citrullination of antigens in immune complexes in patients with rheumatoid arthritis

Katleen Van SteendamKelly TillemanMarlies De CeuleneerMaarten DhaenensDirk ElewautFilip De KeyserDieter Deforce

Identification of factors in follicular fluid and/or serum involved in in vitro cumulus expansion of porcine oocytes

Jo BijttebierKelly TillemanDieter DeforceMaarten DhaenensAnn Van SoomDominiek Maes

LC-MS metabolic profiling of Arabidopsis thaliana plant leaves and cell cultures: optimization of pre-LC-MS procedure parameters

Ruben T'KindtLieven De VeylderMichael StormeDieter DeforceJan Van Bocxlaer

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Proteomics in liver fibrosis is more than meets the eye

Kin Jip CheungKelly TillemanDieter DeforceIsabelle ColleHans Van Vlierberghe

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Proteomics in rheumatology: The beginning of a fairy tale?

Stijn LambrechtKelly TillemanDirk ElewautDieter Deforce

A1 Journal Article in PROTEOMICS CLINICAL APPLICATIONS

Response to paroxetine and venlafaxine in OCD is not determined by common CYP2D6 polymorphisms

Filip Van NieuwerburghD. DenysDieter Deforce

SMALL HEAT-SHOCK PROTEINS, NOVEL IDENTIFIED MEDIATORS OF MATRIX GENE EXPRESSION, ARE DIFFERENTIALLY EXPRESSED IN OA CHONDROCYTES

Stijn LambrechtAugust VerbruggenDirk ElewautDieter Deforce

Serotonin Related Genes Affect Antidepressant Treatment in Obsessive-Compulsive Disorder

Filip Van NieuwerburghDieter DeforceD DENYS

A2 Journal Article in Progress in Neurotherapeutics and Neuropsychopharmacology

Serotonin related genes affect antidepressant treatment in obsessive-compulsive disorder

Filip Van NieuwerburghDieter DeforceDamiaan Denys

Bookchapter in Progress in Neurotherapeutics and Neuropsychopharmacology

Shorter CAG repeats in the androgen receptor gene may enhance hyperandrogenicity in polycystic ovary syndrome

Filip Van NieuwerburghDominic StoopPatrick CabriMarc DhontDieter DeforcePetra De Sutter

A1 Journal Article in GYNECOLOGICAL ENDOCRINOLOGY

Shorter CAG repeats in the androgen receptor gene may enhance hyperandrogenicity in polycystic ovary syndrome (PCOS)

Filip Van NieuwerburghDominic StoopPatrick CabriMarc DhontPetra De SutterDieter Deforce

Synovial detection and autoantibody reactivity of processed citrullinated isoforms of vimentin in inflammatory arthritides

Kelly TillemanKatleen Van SteendamTineke CantaertFilip De KeyserDirk ElewautDieter Deforce

A1 Journal Article in RHEUMATOLOGY

The HCV Serum proteome: A search for fibrosis protein markers

Kin Jip CheungKelly TillemanDieter DeforceIsabelle ColleHans Van Vlierberghe

Transgenic rat OX62(+) DCs exhibit multiple cellular deficiencies and the tolerigenic CD4(-) subset suffers reduced viability

Maarten DhaenensIngrid FertSimon GlatignySaskia HaerinckCeline Hacquard-BouderClaudine AndréDirk ElewautDieter DeforceMaxime Breban

Tryptic peptide analysis of protein binders in works of art by liquid chromatography–tandem mass spectrometry

Wim FremoutMaarten DhaenensSteven SaverwynsJana SanyovaPeter VandenabeeleDieter DeforceLuc Moens

2007

A single early activation of invariant NK T cells confers long-term protection against collagen-induced arthritis in a ligand-specific manner

Ken CoppietersKatrien Van BenedenPeggy JacquesPieter DewintAnn VervloetBert Vander CruyssenSerge Van CalenberghGuangwu ChenRichard FranckAugust Verbruggen et al.

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Broad-spectrum separations in metabolomics using enhanced polar LC stationary phases: A dedicated evaluation using plant metabolites

Ruben T'KindtG ALAERTSY VANDER HEYDENDieter DeforceJan Van Bocxlaer

A1 Journal Article in JOURNAL OF SEPARATION SCIENCE

Deguelin inhibits expression of I kappa B alpha protein and induces apoptosis of B-CLL cells in vitro

Ben GeeraertsBarbara VanhoeckeWim Vanden BergheJan PhilippéFritz OffnerDieter Deforce

A1 Journal Article in LEUKEMIA

Edelfosine protects precultured heart fragments against the invasion of malignant cells through altered sialylation

S VAN SLAMBROUCKWFA STEELANTM LOPEZMA RECCHIY BOILLY-MARERErik BruyneelP DELANNOYA VERBERTElfrida Van Den EeckhoutDieter Deforce

A1 Journal Article in ONCOLOGY REPORTS

In pursuit of B-cell synovial autoantigens in rheumatoid arthritis: Confirmation of citrullinated fibrinogen, detection of vimentin, and introducing carbonic anhydrase as a possible new synovial autoantigen

Kelly TillemanAnn UnionT CANTAERTS DE KEYSERA DANIELSDirk ElewautFilip De KeyserDieter Deforce

A1 Journal Article in PROTEOMICS CLINICAL APPLICATIONS

NKT cells: manipulable managers of joint inflammation

Ken CoppietersPieter DewintKatrien Van BenedenPeggy JacquesSylvie SeeuwsAugust VerbruggenDieter DeforceDirk Elewaut

A1 Journal Article in RHEUMATOLOGY

Prediction of response to paroxetine and venlafaxine by serotonin-related genes in obsessive-compulsive disorder in a randomized, double-blind trial

Damiaan DenysFilip Van NieuwerburghDieter DeforceHerman GM Westenberg

A1 Journal Article in JOURNAL OF CLINICAL PSYCHIATRY

Tackling the challenge of quantifying co-migrating proteins in two dimensional gel electrophoresis-based proteome analysis

Maarten DhaenensSofie VandecasteeleDieter Deforce

Tyrosine phosphorylation and lipid raft association of pseudorabies virus glycoprotein E during antibody-mediated capping

Ann DesplanquesHans NauwynckKelly TillemanDieter DeforceHerman Favoreel

A1 Journal Article in VIROLOGY

Virilizing clinical features of PCO patients with normal androgen levels may result from a shorter CAG repeat length of the androgen receptor gene

D STOOPFilip Van NieuwerburghY ZAHNLENKA GALAJDOVAKAATJE DIRCKXP CABRIEVA VERSCHUERENJan GerrisMarc DhontDieter Deforce et al.

2006

A unique LT alpha beta dependent pathway regulates thymic emigration of V alpha 14i NKT cells

Pieter DewintAnn-Sophie FrankiKatrien Van BenedenKirsten HammondStijn LambrechtGeorges LeclercqDieter DeforceMitchell KronenbergDirk Elewaut

A unique lymphotoxin alpha beta dependent pathway regulates thymic emigration of V alpha 14iNKT cells

Dirk ElewautAnn-Sophie FrankiKatrien Van BenedenPieter DewintKirstin HammondGeorges LeclercqDieter DeforceMitchell Kronenberg

A unique lymphotoxin alpha,beta-dependent pathway regulates thymic emigration of V alpha 14 invariant natural killer T cells

Ann-Sophie FrankiKatrien Van BenedenPieter DewintKJL HAMMONDStijn LambrechtGeorges LeclercqM KRONENBERGDieter DeforceDirk Elewaut

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association between serotonergic candidate genes and specific phenotypes of obsessive compulsive disorder

D DENYSFilip Van NieuwerburghDieter DeforceHGM WESTENBERG

A1 Journal Article in JOURNAL OF AFFECTIVE DISORDERS

Association between the dopamine D-2 receptor TaqI A2 allele and low activity COMT allele with obsessive-compulsive disorder in males

D DENYSFilip Van NieuwerburghDieter DeforceH WESTENBERG

A1 Journal Article in EUROPEAN NEUROPSYCHOPHARMACOLOGY

Comparison of the anti-human citrullinated fibrinogen antibodies assayed by ELISA with 2 other ACPA assays: Diagnostic value and agreement between assays

Bert Vander CruyssenL NOGUEIRATineke CantaertC CAVELLEEN DE RYCKEM SEBAGDieter DeforceDirk ElewautG SERREFilip De Keyser

DIFFERENTIAL PROTEOME ANALYSIS OF NORMAL AND OA-AFFECTED CHONDROCYTES

Stijn LambrechtAugust VerbruggenPETER VERDONKDirk ElewautDieter Deforce

Development and evaluation of different normalization strategies for gene expression studies in Candida albicans biofilms by real-time PCR

Heleen NailisTom CoenyeFilip Van NieuwerburghDieter DeforceHans Nelis

A1 Journal Article in BMC MOLECULAR BIOLOGY

Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays

Bert Vander CruyssenTineke CantaertL NOGUEIRAC CLAVELLEEN DE RYCKEA DENDOVENM SEBAGDieter DeforceC VINCENTDirk Elewaut et al.

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Disease mechanism in Spondyloarthropathies: a proteome analysis of spleen dendritic cells from HLA-B27 transgenic rats.

Maarten DhaenensIngrid FertCecile Hacquard-BouderDirk ElewautDieter DeforceMaxime Breban

Entering the era of proteomics in rheumatalogy

Stijn LambrechtDieter DeforceDirk Elewaut

A2 Journal Article in Expert Opinion on Drug Discovery

Long-term IFN-gamma dependent efficacy of activated V alpha 14I natural killer T-cells in the prevention of collagen-induced arthritis

Ken CoppietersKatrien Van BenedenAnn VervloetPieter DewintPeggy JacquesSara GroeneboerMoriya TsujiAugust VerbruggenDieter DeforcePatrick Matthys et al.

Long-term IFN-gamma dependent efficacy of activated valpha141 natural killer T cells in the prevention of collagen-induced arthritis

Katrien Van BenedenKen CoppietersAnn VervloetB VandercruyssenPeggy JacquesPieter DewintB De KlerckH HeremansM TsujiG Verbruggen et al.

Protein expression profiling of normal and osteoarthritic chondrocytes points to distortion of vimentin organisation in osteoarthritis

Stijn LambrechtG VERBRUGGENPETER VERDONKDirk ElewautDieter Deforce

Quantitation of artemisinin and its biosynthetic precursors in Artemisia annua L. by high performance liquid chromatography - electrospray quadrupole time-of-flight tandem mass spectrometry

Filip Van NieuwerburghSofie Vande CasteeleLies MaesAlain GoossensDirk InzéJan Van BocxlaerDieter Deforce

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

The diagnostic value of the anti-human citrullinated fibrinogen antibodies by elisa compared to anti-CCP2 antibodies, and their agreement with ACPA detected by 3 other substrates

Bert Vander CruyssenL NogueiraT CantaertC CavelLies De RyckeM SebagDieter DeforceDirk ElewautG SerreFilip De Keyser

2005

A unique LT alpha beta dependent pathway regulates thymic emigration of V alpha 14i NKT cells

Ann-Sophie FrankiKatrien Van BenedenPieter DewintKJL HAMMONDS LAMBRECHTG LECLERCQM KRONENBERGDieter DeforceDirk Elewaut

A unique LT dependent pathway regulates thymic emigration of V alpha 14i NKT cells

Ann-Sophie FrankiKatrien Van BenedenPieter DewintStijn LambrechtDieter DeforceDirk Elewaut

Analysis of nucleic acid constituents by on-line capillary electrophoresis-mass spectrometry

An WillemsDieter DeforceCarlos Van PeteghemJan Van Bocxlaer

A1 Journal Article in ELECTROPHORESIS

Chronically inflamed synovium from spondyloarthropathy and rheumatoid arthritis investigated by protein expression profiling followed by tandem mass spectrometry

Kelly TillemanKatrien Van BenedenAline DhondtIlse HoffmanFilip De KeyserEric VeysDirk ElewautDieter Deforce

A1 Journal Article in PROTEOMICS

Deguelin, a PI3K/Akt inhibitor induceds apoptotic killing of B-CLL cells in vitro

Ben GeeraertsFritz OffnerDieter Deforce

Development of a quality control method for the characterization of oligonucleotides by capillary zone electrophoresis-electrospray ionization-quadrupole time of flight-mass spectrometry

An WillemsDieter DeforceCarlos Van PeteghemJan Van Bocxlaer

A1 Journal Article in ELECTROPHORESIS

Differential expression of hypoxia activated proteins in synovial tissue of inflammatory arthritides

Kelly TillemanAline DhondtPieter DewintFilip De KeyserDirk ElewautDieter Deforce

Differential proteome analysis of Chronic lymphocytic leukemia subtypes

Ben GeeraertsAline DhondtDirk ElewautJan Van BocxlaerDieter Deforce

Ly49 and CD94/NKG2 receptor acquisition by NK cells does not require lymphotoxin-beta receptor expression

Frederik StevenaertKatrien Van BenedenVeerle De ColvenaerAnn-Sophie FrankiVeronique DebackerTom BoterbergDieter DeforceK PFEFFERJean PlumDirk Elewaut et al.

A1 Journal Article in BLOOD

Lymphotoxin alpha 1 beta 2: a critical mediator in V alpha 14i NKT cell differentiation

Ann-Sophie FrankiKatrien Van BenedenPieter DewintIvan MeeusEric VeysDieter DeforceDirk Elewaut

A1 Journal Article in MOLECULAR IMMUNOLOGY

Lymphotoxins alpha and beta are indispensable for phenotypical and functional development of V alpha 14i NKT cells during fetal ontogeny

Ann-Sophie FrankiKatrien Van BenedenPieter DewintStijn LambrechtDieter DeforceDirk Elewaut

Prediction of response to paroxetine and venlafaxine by serotonin related genes in obsessive-compulsive disorder

Damiaan DenysFilip Van NieuwerburghDieter DeforceHerman Westenberg

Rheumatology: a close encounter with proteomics

Kelly TillemanDieter DeforceDirk Elewaut

A1 Journal Article in RHEUMATOLOGY

Synthesis of [I-123]-3-(4-iodobenzyl)-1,2,3,4-tetrahydro-8-hydroxychromeno[3,4-c]pyri din-5-one, a potential dopamine D4 ligand for SPECT studies

Ludovicus StaelensRuth OltenfreiterBart CornelissenPeter BlanckaertFilip De VosDieter DeforceRudi DierckxGuido Slegers

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

X linked agammaglobulinaemia and rheumatoid arthritis

G VERBRUGGENSofie De BackerDieter DeforcePieter DemetterClaude CuvelierEric VeysDirk Elewaut

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

2004

Homeostasis of CD4+CD25+regulatory T cells in naive and arthritic mice

Katrien Van BenedenA VAN DER AADieter DeforceEric VeysDirk Elewaut

Indispensable role of lymphotoxins alpha and beta in phenotypical and functional development of V alpha 14i NKT cells during fetal ontogeny

Ann-Sophie FrankiKatrien Van BenedenEric VeysDieter DeforceDirk Elewaut

Lymphotoxin beta receptor mediated activation of RelB by NIK defines a unique signaling pathway for the development of V alpha 14i NKT cells

Ann-Sophie FrankiKatrien Van BenedenR ShaikhDieter DeforceDirk Elewaut

Lymphotoxins alpha and beta are indispensable for phenotypical and functional development of V alpha 14i NKT cells during fetal ontogeny

Katrien Van BenedenAnn-Sophie FrankiEric VeysDieter DeforceDirk Elewaut

Lymphotoxins alpha and beta are indispensable for phenotypical and functional development of V alpha 14i NKT cells during fetal ontogeny

Katrien Van BenedenAnn-Sophie FrankiEric VeysDieter DeforceDirk Elewaut

Lymphotoxins alpha and beta are indispensable for phenotypical and functional development of V alpha 14i NKT cells during fetal ontogeny

Pieter DewintKatrien Van BenedenAnn-Sophie FrankiDieter DeforceDirk Elewaut

Optimization of solid-phase extraction for a liquid chromatographic-tandem mass spectrometric general unknown screening procedure by means of computational techniques

Tineke DecaesteckerWilly LambertCarlos Van PeteghemDieter DeforceJan Van Bocxlaer

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Protein expression profiling of inflamed synovial tissue in rheumatoid arthritis, spondyloarthropathy and osteoarthritis

Kelly TillemanAline DhondtIlse HoffmanFilip De KeyserEric VeysDieter DeforceDirk Elewaut

Rapid characterization of oligonucleotides by capillary liquid chromatography-nano electrospray quadrupole time-of-flight mass spectrometry

An WillemsDieter DeforceWilly LambertCarlos Van PeteghemJan Van Bocxlaer

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Synovial tissue proteomics in rheumatoid arthritis and spondyloarthropathy

Kelly TillemanKatrien Van BenedenFilip De KeyserEric VeysDieter DeforceDirk Elewaut

The determination of cocaine, benzoylecgonine, and cocaethylene in small-volume oral fluid samples by liquid chromatography-quadrupole-time-of-flight mass spectrometry

K CLAUWAERTT DECALESTECKERKjell MortierWilly LambertDieter DeforceCarlos Van PeteghemJan Van Bocxlaer

A1 Journal Article in JOURNAL OF ANALYTICAL TOXICOLOGY

2003

Exact mass measurement of product ions for the structural confirmation and identification of unknown compounds using a quadrupole time-of-flight spectrometer: a simplified approach using combined tandem mass spectrometric functions

Karine ClauwaertSofie Vande CasteeleBart SinnaeveDieter DeforceWilly LambertCarlos Van PeteghemJan Van Bocxlaer

A1 Journal Article in RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Lymphotoxin beta receptor mediated activation of RelB by NIK defines a unique signaling pathway for the development of V alpha 14i NKT cells

Ann-Sophie FrankiKatrien Van BenedenR ShaikhDieter DeforceM VeysC WareM KronenbergDirk Elewaut

The protein expression pattern of CLL cells is stable over six months intervals

Ben GeeraertsJan Van BocxlaerWilly LambertCarlos Van PeteghemDieter DeforceDirk Elewaut

2002

Analysis of benzo(a)pyrene diol epoxide-DNA adducts by capillary zone electrophoresis-electrospray ionization-mass spectrometry in conjunction with sample stacking

An WillemsDieter DeforceElfrida Van Den EeckhoutWilly LambertCarlos Van PeteghemAndreas De LeenheerJan Van Bocxlaer

A1 Journal Article in ELECTROPHORESIS

Flemish population data using the AmpF/STR Profiler (TM) PCR amplification kit.

DEO VAN HOOFSTATSaskia HaerinckDieter Deforce

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL

Latent sensitivity to Fas-mediated apoptosis after CD40 ligation may explain activity of CD154 gene therapy in chronic lymphocytic leukemia.

P CHUDieter DeforceIM PEDERSENY KIMS KITADAJC REEDTJ KIPPS

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simultaneous, quantitative determination of opiates, amphetamines, cocaine and benzoylecgonine in oral fluid by liquid chromatography quadrupole-time-of-flight mass spectrometry

Kjell MortierKristof MaudensWilly LambertKarine ClauwaertJan Van BocxlaerDieter DeforceCarlos Van PeteghemAndreas De Leenheer

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

2001

Analysis and identification of MHC-associated peptides using mass spectrometry

Dieter DeforceElfrida Van Den Eeckhout

Bookchapter in Recent Research Developments in Analytical Chemistry, vol. 1

Analysis of DNA damage using capillary zone electrophoresis and electrospray mass spectrometry

Dieter DeforceElfrida Van Den Eeckhout

Bookchapter in Capillary Electrophoresis of Nucleic Acids

2000

Analysis of oligonucleotides by ESI-MS

Dieter DeforceElfrida Van Den Eeckhout

A1 Journal Article in ADVANCES IN CHROMATOGRAPHY

Characterization of CD4 cytotoxic T cells specific for autologous chronic lymphocytic leukemia B cells

P ChuDieter DeforceLZ RassentiTJ Kipps

Generation of CD8+ T cell lines with specific cytotoxicity for autologous chronic lymphocytic leukemia B cells

Dieter DeforceP ChuLZ RassentiR MendozaE RazTJ Kipps

Infectivity of hematopoetic cells with the semliki forest virus

T GutjahrN TsukadaD ElingDieter DeforceJ Kipps

Liquid chromatography-mass spectrometry in forensic toxicology

Jan Van BocxlaerKarine ClauwaertWilly LambertDieter DeforceElfrida Van Den EeckhoutAndreas De Leenheer

A1 Journal Article in MASS SPECTROMETRY REVIEWS

1999

Analysis of melphalan adducts of 2 '-deoxynucleotides in calf thymus DNA hydrolysates by capillary high-performance liquid chromatography-electrospray tandem mass spectrometry.

I HOESF LEMIEREW VAN DONGENK VANHOUTTEEL ESMANSD VAN BOCKSTAELEZ BERNEMANDieter DeforceElfrida Van Den Eeckhout

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B

DNA typing of fingerprints using capillary electrophoresis: Effect of dactyloscopic powders.

DEO VAN HOOFSTATDieter DeforceIPH DE PAUWElfrida Van Den Eeckhout

A1 Journal Article in ELECTROPHORESIS

1998

Analysis of the DNA adducts of phenyl glycidyl ether in a calf thymus DNA hydrolysate by capillary zone electrophoresis-electrospray mass spectrometry : evidence for phosphate alkylation

Dieter DeforceFilip LemièreIlse HoesRebecca E MillecampsEddy L EsmansAndreas De LeenheerElfrida Van Den Eeckhout

A1 Journal Article in CARCINOGENESIS

Analysis of the DNA damage induced by phenyl glycidyl ether using capillary zone electrophoresis-electrospray mass spectrometry

Dieter DeforceF LemièreEL EsmansAndreas De LeenheerElfrida Van Den Eeckhout

A1 Journal Article in ANALYTICAL BIOCHEMISTRY

Characterization of DNA oligonucleotides by coupling of capillary zone electrophoresis to electrospray ionization Q-TOF mass spectrometry

Dieter DeforceJ RaymackersL MeheusF Van WijnendaeleAndreas De LeenheerElfrida Van Den Eeckhout

A1 Journal Article in ANALYTICAL CHEMISTRY

Comparison of slab gel electrophoresis and capillary electrophoresis for the detection of the fluorescently labeled polymerase chain reaction products of short tandem repeat fragments.

Dieter DeforceREM MILLECAMPSDavid Van HoofstatElfrida Van Den Eeckhout

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

DNA typing of Fingerprints and Skin Debris: Sensitivity of Capillary Electrophoresis in Forensic Applications using Multiplex PCR

David Van HoofstatDieter DeforceVeerle BrochezIsabel De PauwK JanssensM MestdaghR MillecampsEls Van GeldreElfrida Van Den Eeckhout

Onderzoek van de DNA-adductvorming van epoxiden en platinaverbindingen met behulp van capillaire zone elektroforese en gekoppelde elektrospray massaspectrometrie

Dieter DeforceElfrida Van Den EeckhoutEL Esmans

Population genetic study of four short tandem repeat loci in the Belgian population, using capillary electrophoresis.

David Van HoofstatDieter DeforceREM MillecampsVeerle BrochezEls Van GeldreAnnemieke VergauweA SijsElfrida Van Den Eeckhout

A1 Journal Article in ELECTROPHORESIS

Preparative capillary zone electrophoresis in combination with off-line graphite furnace atomic absorption for the analysis of DNA complexes formed by a new aminocoumarine platinum (II) compound

Dieter DeforceG KokotosEL EsmansAndreas De LeenheerElfrida Van Den Eeckhout

A1 Journal Article in ELECTROPHORESIS

1997

Synthesis and in vitro cytotoxicity of aminocoumarin platinum II complexes.

G KOKOTOSV THEODOROUDieter DeforceC TZANGRAKIElfrida Van Den Eeckhout

A2 Journal Article in Anticancer Res.

Synthesis and in vitro cytotoxicity of aminocoumarin platinum(II) complexes.

G KOKOTOSV THEODOROUC TZOUGRAKIDieter DeforceEG VANDENEECKHOUT

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1996

Analysis of DNA adducts in DNA hydrolysates by capillary zone electrophoresis and capillary zone electrophoresis electrospray mass spectrometry.

Dieter DeforceFPK RYNIERSEG VANDENEECKHOUTF LEMIEREEL ESMANS

A1 Journal Article in ANALYTICAL CHEMISTRY

1995

Capillary zone electrophoresis in the elucidation of DNA adduct formation with phenylglycydyl ethers as carcinogenic compounds

Dieter DeforceF RYNIERST ROCKElfrida Van Den Eeckhout