Design and development of carbapenem- and cephalosporin-based monocyclic beta-lactam derivatives to address antibiotic-insensitive penicillin-binding proteins

Aziridine-based CO2 capture – a new approach toward the synthesis of fluorinated oxazolidinones

Aziridine-based CO2 capture – a new approach toward the synthesis of fluorinated oxazolidinones.

Catalytic carbonylation of aziridines to novel beta-lactams as versatile building blocks in heterocyclic chemistry

Catalytic synthesis and ring opening of aziridines – novel protocols for the preparation of valuable nitrogen-containing target compounds

Design and development of new selective HDAC6 inhibitors with applications in cancer therapy

Development of hybrid molecules targeting glucocorticoid and peroxisome proliferator-activated receptor-based heterodimers to combat inflammation

Development of steroid-based GR-PPARα conjugates for the treatment of chronic inflammatory diseases

Employment of functionalized azetin-2-ones for the synthesis of biologically relevant C-, N- and spiro-fused beta-lactams.

Exploration of HDAC6 inhibitors as anti-inflammatory agents – linking HDAC6 chemistry with inflammation biology

Explorations in quinoline chemistry – towards the development of novel piperidine-quinoline hybrids with antimalarial activity and nitroxoline analogs with anti-tumor activity

From thiazepane curcuminoid hit structures to new anticancer lead compounds

Generation and application of 2-oxoazetidin-4-yl anions for the construction of new, biologically relevant C-, N- and spiro-fused beta-lactams

Opportunity to develop novel HDAC6 inhibitors for therapeutic use

Out of limbo: a toolbox to eliminate ambiguity around HDAC6, offering a novel therapeutic opportunity against multiple myeloma.

Out of limbo: a toolbox to eliminate ambiguity around HDAC6, offering a novel therapeutic opportunity against multiple myeloma.

Regio- and stereoselective ring expansions of 2-(2-cyanoethyl)aziridines toward functionalized pyrrolidines and piperidines

Stereoselective synthesis of β-lactams and their use in multicomponent reactions

Synthesis and biological assessment of novel β-lactamase inhibitors in the framework of tuberculosis therapy in India

Synthesis and biological evaluation of new beta-lactam containing inhibitors of penicillin-binding proteins from resistant bacteria.

Synthesis and eva luation o f new inhibitors of penicillin-binding proteins from resistant bacteria en route to new antibacterial agents

Curcumin-derived functionalized thiazepanes to selectively target colon cancer cell

Curcumin-derived functionalized thiazepanes to selectively target colon cancer cells

New entries to functionalized beta-lactams as versatile building blocks in heterocyclic chemistry

Purchase of GC-MS equipment for the analysis of volatile organic compounds.

Purchase of LC-MS equipment for the analysis of organic compounds, reaction mixtures and natural extracts

Safe and efficient dehydration of organic solvents for synthesis purposes by means of a ‘Solvent Purification System’

Study of 2-substituted 2-(bromomethyl)aziridines as flexible synthons in heterocyclic chemistry

Sustainable chemistry for the synthesis of fine chemicals

Trifluorinated imines as building blocks for the synthesis of new trifluoromethylated azaheterocycles

Validation of a small molecule system for a safer treatment of chronic inflammation

Catalytic synthesis and ring opening of aziridines – novel protocols for the preparation of valuable nitrogen-containing target compounds