Project

Synthesis and biological assessment of novel β-lactamase inhibitors in the framework of tuberculosis therapy in India

Duration
01 October 2018 → Ongoing
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Organic chemistry
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Microbiology
    • Laboratory medicine
    • Laboratory medicine
    • Microbiology
Keywords
Tuberculosis India Organic synthesis Biological evaluation β-lactams
 
Project description

Tuberculosis (TB) is an infectious disease responsible for 220.000 deaths per year in India, imposing an immense burden on the country’s health care system. This project aims at establishing an innovative approach in anti-TB therapy by designing β-lactamase inhibitors that could allow classical
β-lactam antibiotics to exert their antibacterial action against (resistant) Mycobacterium tuberculosis strains.