Deep molecular and functional phenotyping of γδ T cells in spondyloarthritis

Mechanoinflammation in arthritic disease

Advances in primary Sjörgen’s Syndrome diagnosis and patient stratification. First results from the BeSSTT cohort

Discovery of novel, selective GPCR agonists for the treatment of inflammatory conditions.

Doctoral project Céline La

Doctoral project Guillaume Planckaert

Doctoral project Katelijne De Wilde

Doctoral project Lode Melis

Doctoral project Matthias Jarlborg

Doctoral project Nele Juchtmans

Involvement of gut dysbiosis during spondyloarthritis: Pathogenicity of Ruminococcus gnavus

Mechanisms of inflammation and associated tissue damage in musculoskeletal diseases

Mechanosensing via adhesion G-protein coupled receptors (aGPCR) in musculoskeletal disease

Monocyte-directed nanotherapy for resolution of chronic arthritis

Sjogren’s syndrome pathophysiology investigating trial: the “SSPIT” concept

Stratification of patients with spondyloarthritis

The role of γδ-Tcells in combined joint and gut pathology in spondyloarthritis

Doctoral project Aad Dhollander

Doctoral project Catherine Van Der Straeten

Doctoral project Laure Van Steenbergen

Doctoral project Laurien Van Heddegem

Doctoral project Nathan Vastesaeger

Doctoral project Philippe Carron

Doctoral project Pieter Hindryckx

Doctoral project Tine Vanhaverbeke

Improving diagnosis of primary immunodeficiencies using computational cytometry

Microbial contributions to gut and joint disease

Quorum Sensing Peptides in Sarcopenia: moving towards personalised therapies

Sarcopenia: A Gut-Feeling for Quorum Sensing Peptides and Natural Killer T Cells

A proof of concept study for a novel mechanism of action to combat osteoporosis by inhibiting osteoclastogenesis

A unique imaging system combining flow cytometry and confocal microscopy

BeSSTT: Belgian Sjörren's Syndrome transition trial

Characterization of novel antibody targets in rheumatoid arthritis

Deciphering the functional phenotype of ?d T cells in spondyloarthritis.

Deciphering the functional phenotype of γδ T cells in spondyloarthritis.

Deep molecular and functional phenotyping of γδ T cells in spondyloarthritis

DNA methylation markers to predict treatment success of biologicals in Crohn’s disease.

Dynamic modulation of disease progression in chronic gut and joint inflammation in spondyloarthritides

Dynamic visualization of TCR-induced NKT cell arrest and anergy induction in vivo

Functional profiling and therapeutic tolerization of macrophages in type 1 diabetes

GDF15-mAbs: development assay and evaluation therapy

How T cell autoreactivity develops in early rheumatoid arthritis: the smoking gun hypothesis

Identification and characterization of type 2 NKT ligands induced by endoplasmic reticulum stress in cancer immunotherapy

Identifying the functional outcome of different antigen presenting cells for NKT cell activation in the liver.

Immune therapy in MM: can INKT cells be targeted?

Inhibiting pathogenic bone loss in arthritis: a proof of concept study

Investigation of novel targets for therapeutic intervention in chronic gut and joint inflammation in spondyloarthritides

in vivo visualization of NKT cell-mediated anti-tumor activity

IUAPVII/96/Elewaut

Mechanosensing via adhesion G protein-coupled receptors (aGPCR) in musculoskeletal disease

Modulation of host-microbial interplay in spondyloarthritis

Molecular elucidation of polarized cytokine responses induced by structural changes in glycolipid antigenten presented by CD1d.

Monitoring innate immunity in arthritis and mucosal inflammation

MOnocyte-directed NAnotherapy for Resolution of CHronic arthritis (MONARCH).

Preservation and repair of the joint: meeting the osteoarthritis challenge

Purchase and installation of a bedding dump system for the SPF animalarium MRB2

Regulation of emigration invariant killer T cells in the thymus.

Regulation of emigration of invariant natural killer T cells from the thymus

Rehabilitation in Axial spondyloarthritis

Research into cellular processes and their therapeutic potential, involved in impaired chondrocyte metabolism in the pathogenesis of OA.

Research into the role of GDF-15 in rheumatological disorders in vivo

Role of biomechanical stress in inflammatory arthritis

Role of biomechanical stress in inflammatory arthritis

Role of endogenous NKT ligands induced by Endoplasmic Reticulum stress in NASH-driven hepatocellular carcinoma

Role of endoplasmic reticulum (ER) stress induced immunogenic lipids in cancer immunotherapy

Role of group 2 innate lymphoid cells in knee ligament homeostasis during osteoarthritis

Role of homeostasis of lymphoid structures in inflammation

Role of innovative research tools as biomarkers to predict severe clinical complications in Systemic Sclerosis.

Role of intestinal barrier dysfunction for the pathogenesis of spondyloarthritis

Role of mechanical strain in spondyloarthritis: a proof of concept study

Role of natural killer T cells in the pathophysiology and treatment of experimental arthritis

Role of polarized analogues of alpha-galactosylceramide on the antiviral immune response during CMV infections

Role of the intestinal microbiome in spondyloarthritides

Sjögren's syndrome pathophysiology investigating trial: the SSPIT concept

Sjögren’s Syndrome Pathophysiology Investigating Trial: the SSPIT concept

Study of cellular mechanisms and their therapeutic potential, involved in the distorted chondrocyte metabolism during the development of osteoarthritis.

Study of the impact of CYLD cleavage on lymphocyte function in vivo and its potential contribution to inflammatory and autoimmune disorders

Study of the interaction of natural killer T cells and regulatory T cells in chronic inflammatory arthritis

Study of the interactions of regulatory T cells in chronic inflammatory arthritis

T cell-mediated modulation of Th1/Th17 balances and its consequences on osteoclastogenesis in autoimmune arthritis

T cell receptor signaling pathways in autoimmune disease

T cell receptor signaling pathways in autoimmune disease: the in vivo role of CYLD cleavage

The role of biomechanical factors and hypoxia in the induction of chronic tendinitis in spondyloarthropathy.

The role of innate-like T cells in combined gut-joint disease in spondyloarthritis

The role of Ltab in the regulation of thymic emigration and peripheral homing of Vai NKT cells

The role of the gut microbiome in sarcopenia

Unraveling the role of S100-DAMPs in seronegative arthritis

Unravelling the molecular mechanisms of how mechanical force triggers inflammatory arthritis

Validation of a new mouse model of systemic sclerosis and study of the B cell as effector cell in the disease

Advanced vaccines and pharmaceuticals targeted to macrophages via sialoadhesin

Cancer sciences xs47 r261 (code 8461)

DEVREPAIR: Paracrine and transcriptional control of cell differentiation in organ development and repair

FullPicture: Combining Spectral Flow Cytometry with High-Speed Cell Imaging to enable comprehensive profiling of plant and animal cells and their components in real time.

Negative regulation of NF-kB in the pathophysiology of rheumatoid arthritis and systemic lupus erythermatosus

Purchase of equipment supporting the sterile housekeeping of mice in the Central Animalarium of the faculty of Medicine and Health Sciences

Quorum Sensing Peptides in Sarcopenia: moving towards personalised therapies

Relation between inflammation of the gut and arthritis in spondyloarthropathy: cellular mechanisms and therapeutical implications

Research into the role of small heat shock proteins and GDF-15 in the biology of cartilage cells and their involvement in the development of osteoarthritis.

SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomics

STRETCH: mechanotransduction in osteoimmunology: an innovative approach towards effective drug for rheumatic diseases

The BD FACS Symphony FACS cell sorter: the most advanced multiparameter fluorescence activated cell sorter that allows the identification and purification of rare cells for further functional characterization

The Best Of Both Worlds: Nuclear Receptor Heterodimers To Battle Against Rheumatoid Arthritis.

The role of the RANKL/RANK/OPG pathway in the cross talk between synovial fibroblasts and synovial myeloid cells in erosive hand osteoarthritis.

The role of the RANKL/RANK/OPG pathway in the cross talk between synovial fibroblasts and synovial myeloid cells in erosive hand osteoarthritis.