Project

Unraveling the role of S100-DAMPs in seronegative arthritis

Duration
01 October 2013 → 30 September 2017
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Orthopaedics
    • Orthopaedics
    • Orthopaedics
Keywords
arthritis innate immunity inflammation
 
Project description

Our goal is to link expression patterns of S100 DAMPs, important drivers of innate immunity, with their mechanistic role in the pathogenesis of joint inflammation in seronegative arthritis. We will use a translational approach combining a variety of unique tools with valuable human samples and multiple validated mouse models.