Project

The role of biomechanical factors and hypoxia in the induction of chronic tendinitis in spondyloarthropathy.

Duration
01 October 2012 → 30 September 2016
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Orthopaedics
    • Orthopaedics
    • Orthopaedics
Keywords
mechanical stresses enthesitis hypoxia
 
Project description

This research project aims to analyze the consequences of frequently occurring stress conditions in joint homeostasis and how these may contribute to chronicity of inflammation in arthritic joint diseases, notably Spondyloarthritis (SpA). The current project therefore aims to unravel the underlying mechanisms of mechanobiology associated inflammation and to explore the role of oxygen levels herein.