Code
3F000408
Duration
01 October 2008 → 30 September 2012
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Medical and health sciences
- Immunology
- Immunology
- Public health care
- Immunology
Keywords
autoimmunity
cytokines
NKT cells
Project description
Stimulation of invariant NKT (iNKT) cells has a positive influence in several autoimmune diseases (which are mainly characterised by th1 activation). Depending on the stimulation by different synthetic analogs of xGalCer (a known iNKT activator) the Th respons can be polarised to a Th1 versus Th2 respons. By this method we want to develop new therapeutic strategies for autoimmune diseases.