CONNEXIN-43 HEMICHANNELS AS PRO-ARRHYTHMIC MEDIATORS IN CARDIAC HYPERTROPHY AND HEART FAILURE

Alliance Research Group: Connexin Signalling Research Group

Astrocyte-endothelial control of the blood-brain barrier examined in normal and ischemic conditions by means of in vivo two-photon microscopy imaging.

Centre for Advanced Light Microscopy

Cofunding core facility - Ghent Light Microscopy (GLiM)

Combined single-channel electrophysiology and fluorescence microscopy for fundamental studies of ion channel function

Combining experimental and computational approaches to investigate arrhythmogenic consequences of connexin hemichannel opening in the heart.

Combining experimental and computational approaches to investigate arrhythmogenic consequences of connexin hemichannel opening in the heart.

Connexin and pannexin channels: regulation, function and applications

Connexin and pannexine channels: molecular insights to applications in health and disease.

Connexin channels and cell death

Connexin-mediated bystander responses in radiation-induced damage of brain endothelial cells

Genetic analysis of cytokines and growth factors involved in the development of radiotherapy complications

hemichannels as novel drug targets in liver fibrosis 2014

High-content image analysis of cell death communication

Impact of peripheral virus infection on the central nervous system

Long-term live cell imaging of intracellular signals and cell death.

Mechanisms underlying connexin-mediated bystander cell death.

Molecular and cellular mechanisms of electrical ecxitability.

Molecular and cellular mechanisms of electrical excitability

New functions of the BH4 domain of Bcl-2: a critical regulator of Ca2+-permeable channels.

Photoactivation of caged compounds and live cell confocal calcium imaging at the subcellular level.

Role of connexin channels in the transfer of apoptotic signals

The role of connexin hemichannels in cardiac arrhythmogenesis

The role of connexin-mediated intercellular signaling in the spread of danger and death signals between brain endothelial cells

the spreading mechanisms and responsible messengers of the radiation induced bystander effect

Understanding connexin hemichannel regulation by intramolecular interactions - a single-channel unitary-current event approach.

Understanding hemichannel regulation by intramolecular interactions - a step forward towards novel tools for in vivo modulation of hemichannel function in the brain

Vesselprotect

Cell-cell communication in the neurogliovascular unit at the level of the blood-brain barrier: focus on endothelial-glial interactions, inflammation and the role of Ca2+ and connexins

Functional changes in the stimulated visual cortex of migraine patients, a combined fMRI and fMRS study

Stimulated emission depletion microscopy (STED): Nanoscopy for innovative research in the life sciences

White light laser-based confocal fluorescence lifetime imaging microscope for multi-parameter 3D live imaging

Controlled delivery of connexin43 mimetic peptide by nanocontainers for therapy of systemic inflammation