Cofunding core facility - Centre of Excellence in Sustainable Pharmaceutical Engineering & Manufacturing – Drug product development

Continuous Direct Compression: Improved process knowledge about the feeding and blending unit operation.

Continuous freeze-drying of biopharmaceuticals

Continuous wet granulation for the production of solid dosage forms

Co-processing of amorphous solid dispersions via spray-drying

Development and characterisation of a continuous freeze-drying technology for unit doses

Doctoral project Anouk Vervaeck

Doctoral project Elien De Coninck

Doctoral project Glenn Verstraete

Doctoral project Kaat De Clercq

Doctoral project Katrien Huyge

Doctoral project Lien Dierickx

Doctoral project Lieselotte De Smet

Doctoral project Severien Standaert

Doctoral project Valérie Vanhoorne

Doctoral project Wesley De Jaeghere

Doctoral project Wouter Grymonpré

Embedding material properties in spray dried powder downstream manufacturing

Evaluation of Fused Filament Fabrication for oral solid dosage form production.

Impact of lubrication on process and tablet quality in a direct compression process.

Impact of material properties on continuous blending

Implementation of 3D printing in (hospital) pharmacies

Improved process and formulation understanding during continuous twin screw wet granulation and downstream processing

Innovative applications of hot-melt extrusion and additive manufacturing for the development of oral solid dosage forms.

Integrating engineering knowledge about additive manufacturing in 3D printing of personalized pharmaceutical tablets using different feedstock materials

Radical improvements in the use of existing and novel antioxidants in pharmaceutical oral solid dosage forms.

The Impact of Binders on Formulation Design in a Continuous Pharmaceutical Manufacturing Process based on Twin Screw Wet Granulation.

Automated visual inspection using deep learning approaches for enhanced quality control of pharmaceutical products.

Development and evaluation of a continuous spin freeze-drying technology: Shedding light on the drying kinetics.

Development and optimisation of lyophilised orally disintegrating tablets using an innovative continuous manufacturing technology

Doctoral project Alexander De Man

Doctoral project Ana Almeida

Doctoral project An-Katrien Vynckier

Doctoral project Bart Claeys

Doctoral project Brecht Vanbillemont

Doctoral project Jeroen Van Renterghem

Doctoral project Jurgen Vercruysse

Doctoral project Olmo Frateur

Doctoral project Shana Van de Steene

Doctoral project Tryfon Digkas

Downstream processing of spray dried amorphous solid dispersions via roller compaction

Influence of selected excipients on stabilityof moisture sensitive solid dosage forms using Accelerated Stability Assessment Programme

In-situ dynamic X-ray imaging of drug release

Making the Insoluble Soluble. PEtOx Based Amorphous Solid Dispersions with High Drug Loadings Using Solvent Electrospinning as a Formulation Technique

Clinical efficacy assessment of an intravaginal device for long term treatment of recurrent bacterial vaginosis

Co-extrusion as novel manufacturing tool for the development of multi-layer fixed dose comination dosage forms.

Compression of tablets: from research and development to production

Continuous linear powder blender for processing of pharmaceuticals

Continuous wet granulation as innovative process technology for the development and production of solid drug forms

Development and characterization of a versatile drug delivery platform using fatty acids as functional excipients

Development of an oral drug delivery formulation for cats using nutritional principles

Hydrophilic thermoplastic polyurethanes for the manufacturing of innovative highly dosed oral sustained release matrices

Hyperthermic intraperitoneal drug delivery of paclitaxel formulations in a rat model for peritoneal carcinomatosis

ICONS: Innovation in pharmaceutical manufacturing of oral solid dosage forms via continuous processing

ICONS:Innovation in pharmaceutical manufacturing of oral solid dosage forms via continuous processing

Identifying critical material properties for continuous blending of pharmaceuticals

Implementation of personalised medical and pharmaceutical devices prepared via 3D printing in hospitals

Improving Drugs Efficacy and Availability

Innovative MulticOmponent Drug dEsign (MODE) for enhancing regional strategic advantages in pharmaceutical and biomedical applications

In-situ characterization of drug release and dissolution processes in sustained-release solid dosage forms

Intraperitoneal Drug Delivery for Peritoneal Carcinomatosis: from Bench to Bedside

Nose-to-brain drug delivery via a muco-adhesive drug carrier

Preclinical development of oleyl-phosphocholine (OIPC: a new promising treatment against leishmaniasis

Site-Specific Drug Delivery

3D printing of personalized pharmaceutical tablets using different feedstock materials via direct extrusion additive manufacturing

An innovative continuous freeze drying platform for orally disintegrating tablets

Bench top flow cytometer

Development of a self-emulsifying solid dosage form via co-processing of polyglycolised glyceride/polymer-mixtures with pharmaceutical carriers: enhancement of the bioavailability of poorly water soluble drugs

Engineering hybrid nanofibrous membranes with superior moisture regulation and controlled antimicrobial action for future wound dressings

Fighting infectious diseases with combination therapy: targetting sociomicrobiological processes to circumvent antimicrobial resistance

Innovative Drug Delivery Systems

Intraperitoneal Drug Delivery for Peritoneal Carcinomatosis: from Bench to Bedside

Magnetic resonance equipment for advanced materials research: molecular characterization of solid, soft, homogeneous and heterogeneous matter in the development of advanced functional materials and chemical catalysis

Multifunctional processing equipment for both conventional and reactive twin screw extrusion (MultiProc)

Multi-mode plate reader.

Solvent electrospinning nanofibers as a novel material for improved polymer-API solid dispersions.

Ussing chamber system for transport studies of drugs through intestinal mucosae

Integrated control of psoroptic mange in Belgian Blue beef cattle