Code
01T02511
Duration
01 March 2012 → 31 December 2012
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Medical and health sciences
- Biomarker discovery and evaluation
- Drug discovery and development
- Medicinal products
- Pharmaceutics
- Pharmacognosy and phytochemistry
- Pharmacology
- Pharmacotherapy
- Toxicology and toxinology
- Other pharmaceutical sciences
Keywords
drug delivery
nasal
muco-adhesion
Project description
The nose-to-brain transport of a drug following nasal adminisatration via a muco-adhesive carrier is evaluated. Initially the muco-adhesive formulation will be optimized, and the drug diffusion through nasal epithelium, mucociliary clearance and irritation of the formulation will be evaluated. In a later phase the pharmacological evaluation of the formulations after nasal administration is planned.