Code
01J12609
Duration
01 January 2009 → 31 October 2013
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Medical and health sciences
- Morphological sciences
- Oncology
- Morphological sciences
- Oncology
- Biomarker discovery and evaluation
- Drug discovery and development
- Medicinal products
- Pharmaceutics
- Pharmacognosy and phytochemistry
- Pharmacology
- Pharmacotherapy
- Toxicology and toxinology
- Other pharmaceutical sciences
- Morphological sciences
- Oncology
Keywords
intraperitoneal perfusion
medical imaging
chemotherapy
Project description
Paclitaxel formulations formulated with cyclodextrins, liposomes and polymer conjugates are in-vitro characterised via solubility, stability and efficiency against tumor cellines. In-vivo the biodistribution, farmacokinetics, tumor penetration and tumor growth delay is determined in a rat model for peritoneal carcinomatosis.