Project

Preclinical development of oleyl-phosphocholine (OIPC: a new promising treatment against leishmaniasis

Code
179P5610
Duration
01 July 2009 → 31 December 2011
Funding
Private funding via IWT/VLAIO
Research disciplines
  • Medical and health sciences
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
Keywords
leishmaniasis
 
Project description

From the perspective of patient's convenience, logistics and other economic considerations, the availability of an oral solid dosage form having excellent stability properties at tropical ambient conditions (high temperature and/or high humidity) will present a real advantage.
Specifics aims are:
1) Determine the pharmaceutical properties of API OIPC
2) Determin if the API is suitable for making tablets and/or capsules.
3) Formulate a trial batch of solid OIPC and determine stability