DEXTRACs: An innovative concept for targeted degradation of extracellular proteins

MITACS: Multivalent Immune TArgeting synthetic Chimeric therapeuticS.

Synergistic engineering of anti-tumor immunity by synthethic biomaterials

Biosynthetic immune-engineering

Doctoral project Alexandra Van Driessche

Doctoral project Hui Li

Doctoral project Sabah Kasmi

Doctoral project Simon Van Herck

Doctoral project Xianyi Cao

Engineering the immune system with advanced biomaterials

immune-engineering

immuun-engineering

Lipid Nanoparticle Formulation of the TLR3 Agonist PolyI:C as a Vaccine Adjuvant.

Lipid Nanoparticle Formulation Strategies for Peptide-Based Cancer Vaccines.

Lipid-polymer conjugates for innate immune activation.

(Macro)molecular strategies for lipid nanoparticles and T cell engineering

Multivalent antibody-recruiting molecules: a novel anti-tumor therapy strategy harnessing the immune response.

Multivalent antibody recruiting molecules as a novel type of cancer immunotherapy.

Preclinical models to validate candidate vaccine adjuvants

Synthesis and evaluation of ionizable lipids for lipid nanoparticle mediated mRNA delivery.

Synthesis and Evaluation of TLR7/8 and STING Agonist Conjugates of Tumor-Targeted Cancer Immunotherapy.

A brighter future for medical imaging - Designing nanocrystals for.

A novel CRISPR/Cas9-based nanomedicine strategy targeting CD4+ cells to cure HIV

Characterizing the immune contexture in mesenteric lymph nodes of colon cancer patients

Development of Tailored Indole-Blocked Triazolinediones for Site-Selective Bioconjugation

Doctoral project Diederick Maes

Doctoral project Dorien Van Lysebetten

Doctoral project Glenn Vanluchene

Doctoral project Joachim Van Guyse

Doctoral project Marvin Nicque

Doctoral project Zhiyue Zhang

An innovative class of ionizable lipids for use in lipid nanoparticle based RNA therapeutics and vaccines

A pre-targeted nanomedicine strategy for in vivo CD8+ T cell engineering.

A targeted nanomedicine strategy for in vivo CD8+ T cell engineering

BOF-ZAP professorship biopharamaceutical technology

BUTGIT: Evaluating the effects of providing butyrate to distinct parts of the gastro-intestinal tract to improve animal health, pathogen colonization and nutrient utilization in livestock animals

COVALENT CELL SURFACE MODIFICATION OF T CELLS FOR TUMOR-TARGETED DELIVERY OF IMMUNOTHERAPY

Cut-and-paste chemistry: from circular plastics to immunotherapeutics

Development of an innovative Fentanyl vaccine

Dynamic polymeric systems as basis for reusable high performance materials and polymer therapeutics

Effective Delivery of Nucleic Acid Therapeutics via Designed Nanocarriers

Engineered microparticulate cancer vaccines based on tumour-specific antigens formulated with immune-modulating polymers

Engineering anti-cancer immunity using polymeric nanoparticles that transform into synthetic cell surface receptors in response to intracellular pH

Engineering the immune system with synthetic biomaterials

Exploring UCST behaviour for the design of degradable polymeric drug nanocarriers

Formulation of vaccine antigens in smart dual-responsive ultrasmall nanoparticles

Glycopolymer-based vaccine nanocarriers

HEPTAMETHINE CYANINE-POLY(ETHYLENE GLYCOL) AS MOLECULAR ANCHOR FOR TUMOR TARGETED CYTOKINE DELIVERY

Hybrid ionizable polymer-lipid mRNA delivery systems for intratumoral immunotherapy

Induction of safe but potent anti-tumour responses via lymph node focused nanoparticle-mediated immune activation

Induction of safe but potent anti-tumour responses via lymph node focused nanoparticle-mediated immune activation

Intelligent polymeric nanoparticles for targeted elimination of tumor-associated macrophages as innovative anti-cancer treatment

JAMs - Janus Antibody-recruiting Macromolecules

Macrocycle-mediated in vivo 'gluing' of T cells and cancer cells to improve T cell killing

MACYCs / Membrane Anchoring CYtokine ChimeraS: Unlocking the full potential of tumor acidity for tumor-targeted cytokine delivery.

MATRACs / Membrane Anchoring Trafficking Chimeras

MATRACs / Membrane Anchoring Trafficking Chimeras

m/mPROTACs : macromolecular multivalent proteolysis targeting chimeras

Monitoring ketal-hydrolysis in synthetic polymer nanoparticles by FRET in living systems

Multi-mode plate reader.

Nanobody-based depletion or reprogramming of protumoral tumor-associated macrophages for the enhancement of therapy response

Non-covalent hapten-immunogen next generation anti-opioid nanovaccines

Normalising tumour pH to bring the STING back in anti-tumour immunity

Polymeric microparticulate vaccine formulations based on hydrogen bonding

Polymer-lipid amphiphile carriers for small molecule immune-modulators

PRECISION IMMUNE-ENGINEERING OF THE TUMOR MICROENVIRONMENT

Solid phase synthesis of functional RAFT chain transfer agents: towards the design of well defined building blocks for multivalent supramolecular nanoassemblies

starter scholarship EVDS Ruben De Coen: OncoRham

Targeted depletion or reprogramming of tumour-associated macrophages with engineered nanomedicines

A MALDI-TOF/TOF MS instrument for (bio)polymer characterization and imaging.

A novel CRISPR/Cas9-based nanomedicine strategy targeting CD4+ cells to cure HIV

A novel CRISPR/Cas9-based nanomedicine strategy targeting CD4+ cells to cure HIV

Bench top flow cytometer

Dynamic polymeric systems as basis for reusable high performance materials and polymer therapeutics

E2E SUD: Transforming the cleaning category with end-to-end technology innovation in new product forms.

Early event in the interaction of antigens/microorganisms with intestinal epithelial cells and intestinal dendritic cells: development of new oral delivery system

Early events in the interaction of antigens/microorganisms with the intestinal epithelial cells and intestinal dendritic cells : development of new innovative oral delivery system.

Engineerde microcapsules for enhanced antigen delivery

Formulation of antigens in immunomodulating microparticles for cancer vaccination

Formulation of antigens in porous spray dried polyelectrolyte microspheres

Formulation of hydrophobic anticancer drugs into intelligent polymer nanoparticles

Formulation of ultrasmall vaccine nanoparticles

FullPicture: Combining Spectral Flow Cytometry with High-Speed Cell Imaging to enable comprehensive profiling of plant and animal cells and their components in real time.

Gold nanoparticle templated vaccine nanocarriers

In Situ Fourier Transform Infrared equipment for polymer analysis.

Introducing mRNA vaccination in chicken: first steps towards a commercial mRNA vaccine against a leading viral infection in chicken

Multivalent dual-responsive polymeric nanoparticles for targeted anti-cancer therapy

PROTECTED TRIAZOLIDINEDIONES AS VERSATILE TOOLS FOR IN SITU BIOCONJUGATION

ReHiFiNMR - Rejuvenation of High-Field NMR equipment for the continued and enhanced characterization of complex molecular architectures and their interactions

Sequence-defined Polymers: Engineering Materials with Biological Precision

Stimulated emission depletion microscopy (STED): Nanoscopy for innovative research in the life sciences

Synthesis and surface chemistry of doped hafnium oxide nanocrystals for dual-modality bio-imaging

The BD FACS Symphony FACS cell sorter: the most advanced multiparameter fluorescence activated cell sorter that allows the identification and purification of rare cells for further functional characterization

Tumor engineering a clinical relevant in vivo model for peritoneal metastasis

BOF-ZAP professorship biopharamaceutical technology