Research Explorer

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Project

Targeted depletion or reprogramming of tumour-associated macrophages with engineered nanomedicines

Outputs and Outcomes

Code

3G044017

Duration

01 January 2017 → 31 December 2020

Funding

Research Foundation - Flanders (FWO)

Promotor

Bruno De Geest

Research disciplines

Medical and health sciences
- Immunology
- Immunology
- Immunology
Engineering and technology
- Chemical product design and formulation
- Process engineering
- Polymeric materials
- Biomaterials engineering

Keywords

tumor associated macrophages nanoparticle

Project description

This project aims at the development of nanoparticles that are selectively recognized and taken up by tumor associated macrophages (TAMs). This phenotype of macrophages is known for its pro-tumoral activity. Therefore we will engineer nanoparticles to reprogram TAMs into an anti-tumoral phenotype to allow fora n improved anti-cancer treatment.

English

Dutch

English

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