Acronym
VetCoVac
Code
F2022/IOF-StarTT/024
Duration
01 November 2022 → 31 October 2024
Funding
Regional and community funding: Industrial Research Fund
Promotor
Research disciplines
-
Medical and health sciences
- Biopharmaceutics
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Engineering and technology
- Chemical product design and formulation not elsewhere classified
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Agricultural and food sciences
- Animal health engineering
- Veterinary conservation medicine, preventive medicine and hygiene
- Veterinary immunology
- Veterinary microbiology
Keywords
veterinary vaccines
infectious bronchitis
mRNA vaccine platform
chicken
Project description
In this project we will introduce our self-amplifying mRNA vaccine platform in chicken. To that end we will design and in vitro validate two mRNA vaccines encoding selected antigens of one of the most important pathogens in poultry production. Subsequently, we will formulate the sa-mRNA vaccines with UGent owned lipid nanoparticles and investigate their immunogencity and protection efficacy in a challenge study in chicken.