Diagnosing HEreditary predisposition syndromes for Childhood cancer: Implementation in clinical PRactice (DHECIPR)

Doctoral project Flavia Zita Francies

Doctoral project Lynn Backers

Fishing for personalized ovarian cancer therapy

In vivo functional evaluation of unclassified and hypomorphic variants in the BRCA2 gene, using CRISPR-mediated prime editing in zebrafish.

In vivo functional evaluation of unclassified variants, found in the breast cancer gene BRCA2, using CRISPR-mediated genome editing in zebrafish

In vivo functional evaluation of variants identified in patients with rare inherited renal diseases using CRISPR-mediated genome editing in zebrafish

Prediction of surgical resectability after FOLFIRINOX chemotherapy for borderline resectable (BR) and locally advanced pancreatic cancer (LADPA)

Psychosocial aspects of diagnosing a hereditary predisposition for childhood cancer

Deep mutational scanning of homologous recombination genes in breast cancer

Genomics for Public Health: personalized medicine for patients with chronic complex disease.

Unraveling the genomic underpinnings of advanced prostate cancer

Analysis of chromosomal radiosensitivity/instability in triple negative and/or young breast cancer patients and patients with Fanconi anemia from South Africa

Cancer predisposition

Cofunding core facility - UGent NGS Core

CONDITIONAL: COvid-19: iNterplay between genetic preDisposITION and immunologicAl Landscape

Development of an in vivo functional assay to determine the pathogenicity of variants in breast cancer genes

Diagnosing HEreditary predisposition syndromes for Childhood cancer: Implementation in clinical PRactice (DHECIPR)

Familial pancreatic cancer: identifying predisposition genes and developing a clinical path for prevention and treatment exploration

HBOC (Hereditary Breast and Ovarian Cancer), a paradigm shift for counseling and treatment of patients with defects in homologous recombination - an explorative study

Heading towards an in vivo predictive test for personalized ovarian cancer treatment: application of novel therapies in zebrafish patient derived xenografts

In vivo functional evaluation of unclassified variants, found in the breast cancer gene BRCA2, using CRISPR-mediated genome editing in zebrafish

Joint Action on Networks of Expertise

Joint Action on Networks of Expertise on Cancer

Joint Action Personalised Cancer Medicine

miRNAs as alternative second hits and potential therapeutic targets in hereditary breast cancer

Multi-omics approach to identify pancreatic cancer biomarkers in liquid biopsies of advanced stage patients by pioneering single cell mass spectrometry of CTCs and (epi)genetics characterization of cfDNA

Next generation sequencing in molecular genetics for hereditary breast cancer, an emerging new strategy

Pancreatic cancer: hope to improve prognosis through thorough analysis of DNA and RNA biomarkers for detection and therapy monitoring in liquid biopsies

Pancreatic cancer: hope to improve prognosis through thorough analysis of DNA and RNA markers for diagnosis and therapy monitoring in liquid biopsies

Towards improved genetic diagnosis for hereditary breast and ovarian cancer: evolution and challenges

Unraveling genetic mechanisms in early onset breast cancer

Zebrafish as a model system to evaluate the causality of variants of unknown clinical significance in hereditary breast cancer

A versatile microscope for the imaging of living and fixed biological samples

Belgian Genome Biobank

Personalized functional genomics in Mendelian diseases: from DNA variants to clinical and bioethical implications

RAPID - Radiosensitivity Analysis for patients with a Primary Immunodeficiency Disease

ThirdGenT: linking third-generation sequencing of (epi)genomes, (epi)transcriptomes and translatomes to life sciences revolutionizes oncology, rare diseases, microbiology, cell and gene technology, developmental and computational biology

Immunomonitoring of patients with non-small cell lung carcinoma treated with a tumor mutanome-targeted dendritic cell vaccine