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Researcher
Jan Gettemans
Profile
Projects
Publications
Activities
Awards & Distinctions
Results
:
ALL
(
28
)
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Title (a-z)
Title (a-z)
Chronological by starting year (new to old)
As
Promotor
01 January 2009 → 31 December 2012
Camelid nanobodies targeting cellular motility factors as a tool to counteract tumor cell migration, invasion and metastasis
Funding: Funding by bilateral agreement (private and foundations)
01 January 2015 → 31 December 2018
Characterization and intracellular delivery of p53 nanobodies with a therapeutic action
Fellows: Anneleen Steels
Funding: Regional and community funding: IWT/VLAIO
01 January 2014 → 31 December 2015
Curtailing gelsolin amyloid formation in a transgene mouse model by means of chaperone nanobodies
Funding: Funding by bilateral agreement (private and foundations)
01 October 2008 → 31 March 2010
Epitope mapping using VHH antibodies (nanobodies) as a tool to understand the moceluar basis of gelsolin activity in cancer cell invasion
Funding: Funding by bilateral agreement (private and foundations)
01 October 2015 → 30 September 2018
Exosome biogenesis and the actin cytoskeleton: an exploratory study using bona fide Camelidae nanobodies
Fellow: Els Beghein
Funding: Regional and community funding: Special Research Fund
01 January 2016 → 31 December 2019
Exploring the therapeutic effect of Akt2/PKB- Beta –neutralising nanobodies in cancer cells
Fellows: Tijs Merckaert
Funding: Research Foundation - Flanders (FWO)
01 October 2009 → 26 February 2015
Gelsolin single domain antibodies (nanobodies) as a therapeutic and research tool in monogenic disorder FAF (familial Amyloidosis of the Finnish type).
Fellow: Wouter Van Overbeke
Funding: Regional and community funding: IWT/VLAIO
01 October 2012 → 22 July 2016
High resolution mapping and inhibition of invadosomes by means of single-chain antibodies against fascin.
Fellow: Isabel Van Audenhove
Funding: Research Foundation - Flanders (FWO), Regional and community funding: Special Research Fund
01 October 2010 → 30 September 2014
High resolution mapping of invadopodia by means of single-chain antobodies
Funding: Regional and community funding: Special Research Fund
15 October 2007 → 16 April 2009
Molecular analysis of the intracellular transport of actin binding proteins, and their role in the nucleus
Funding: Regional and community funding: Special Research Fund
01 October 2016 → 30 September 2017
Molecular anatomy of the invadosome: visualisation by super resolution microscopy and furan-modified fluorescent nanobodies
Fellow: Tim Hebbrecht
Funding: Funding by bilateral agreement (private and foundations)
01 October 2007 → 25 March 2008
Molecular and cell biological analysis of the role of the PDZ proteins in in tumorgeassocierde processes.
Fellow: Kris Meerschaert.kr
Funding: Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
01 October 2010 → 05 January 2016
Nanobody-assisted manipulation of the tumor suppressor p53.
Fellow: Jonas Bethuyne
Funding: Regional and community funding: IWT/VLAIO
01 January 2014 → 31 December 2017
Nanobody footprinting as a tool for high-resolution decomposition of cortactin features that contribute to cancer cell invasion and metastasis, with the prospect of further therapeutic development
Fellow: Laurence Bertier
Funding: Regional and community funding: IWT/VLAIO
01 January 2010 → 31 December 2015
New applications of Camelid single domain antibodies (nanobodies) as research tool and potential therapeutic.
Funding: Research Foundation - Flanders (FWO)
01 January 2014 → 30 June 2017
Offsetting gelsolin degradation in a transgene mouse model by means of chaperone nanobodies
Funding: Funding by bilateral agreement (private and foundations)
01 November 2021 → 31 October 2025
Perturbation of apolipoprotein E4 (apoE4) activity in AD pathology using single domain antibodies and targeting them to the brain
Fellow: Laure Vandevelde
Funding: Regional and community funding: Special Research Fund
01 January 2016 → 31 December 2019
Probing the ultrastructure of invadosomes by super resolution microscopy and neutralizing nanobodies that target different stages of invadosome formation.
Funding: Research Foundation - Flanders (FWO)
01 January 2013 → 31 December 2016
Prospecting to the use of gelsolin nanobodies as a diagnostic and therapeutic tool in the monogenic disorder familial amyloidosis of the Finnish type (FAF).
Funding: Regional and community funding: IWT/VLAIO
01 January 2008 → 31 December 2010
Specific nanobodies as a tool to study the role of gelsolin in tumor cell invasion, and to perturb its activity
Funding: Research Foundation - Flanders (FWO)
01 October 2008 → 30 September 2010
Study of the physiological role of the binding of phospoinositides to the Zonula Occludens proteins
Fellow: Eline Remue
Funding: Regional and community funding: Special Research Fund
01 January 2013 → 31 October 2019
The metastic niche: preparation, function and translational evidence of a permissieve micro environment for cancer dissemination
Funding: Regional and community funding: Special Research Fund
01 October 2012 → 30 September 2013
understanding the effect of cortactin, a pleiotropic regulator of cancer cell invasion, using inhibitory nanobodies perturb its functional domains
Funding: Funding by bilateral agreement (private and foundations)
16 July 2022 → 15 July 2025
Funding: Federal funding: various
As
Copromotor
01 November 2020 → 31 October 2024
Furan-modified peptide and protein ligands for covalent trapping onto cell-surface receptors
Fellow: Laure Tack
Funding: Research Foundation - Flanders (FWO)
01 January 2014 → 05 November 2017
Intelligent edge clouds for resource-intensive, media-rich mobile applications
Fellow: Steven Bohez
Funding: Regional and community funding: IWT/VLAIO
01 June 2015 → 31 May 2017
Longitudinal imaging of cellular dynamics with a biostation IM-Q (microscope with sensitive CCD camera and integrated incubator)
Funding: Regional and community funding: Special Research Fund
01 May 2020 → 30 April 2024
Stimulated emission depletion microscopy (STED): Nanoscopy for innovative research in the life sciences
Funding: Research Foundation - Flanders (FWO)