Research Explorer

Project

New applications of Camelid single domain antibodies (nanobodies) as research tool and potential therapeutic.
Code
3G022310
Duration
01 January 2010 → 31 December 2015
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Systems biology
  • Medical and health sciences
    • Medical biochemistry and metabolism
    • Morphological sciences
    • Oncology
    • Medical biochemistry and metabolism
    • Morphological sciences
    • Oncology
    • Medical biochemistry and metabolism
    • Morphological sciences
    • Oncology
  • Engineering and technology
    • Catalysis and reacting systems engineering
    • Chemical product design and formulation
    • General chemical and biochemical engineering
    • Process engineering
    • Separation and membrane technologies
    • Transport phenomena
    • Other (bio)chemical engineering
Keywords
cancer cells nanobody cytoskeleton
 
Project description
 

Use of single domain antibodies (nanobodies) as antagonists to structural polypeptides in cells with the aim of neutralizing ar blocking their activities. This knowledge is applied to cancer cell motility.