Doctoral project Jana Demaegd

Doctoral project Jan Van den Schilden

Doctoral project Nina De Rocker

Human germline gene editing to overcome transmission of infertility: a proof-of-concept study

Mind the gap: long-read sequencing as a diagnostic tool for deciphering intellectual disability

Nuclear Transfer for female-related infertility and mitochondrial diseases

Deciphering Neurodevelopmental Disorders: the Role of Zinc Finger Homeobox Genes

De novo creation of oocytes

Development of an optimal prediction model for the classification of histological groups of tumors.

Doctoral project Sandra De Ganck

Neoantigen identification on diagnostic biopsies from patients with lung cancer

Neoepitope identification for cancer immunotherapy

The road to functional oocytes: in vitro gametogenesis versus haploidization

The use of Nuclear Transfer technology to overcome female-related infertility

BOF-ZAP professorship in neurogenetics

Cofunding core facility - UGent NGS Core

Detection of somatic mutations and disease-defining methylation patterns in brain tissue and cerebrospinal fluid of patients with non-acquired focal epilepsy

Dissecting the regulatory landscape of MEF2C and FOXG1 in Rett-like manifestations 

Elucidating the dark matter of the genome in central nervous system disorders.

Functional validation of cis-regulatory elements of respectively MEF2C and FOXG1

Identification of novel genes involved in malformations of cortical development (MCD)

Improving outcome of immune checkpoint blockade in lung cancer by combination with a tumor mutanome-targeted dendritic cell vaccine

In-depth comparison and feasibility assessment of an integrated pipeline for neoantigen identification and HLA ligandome sequencing in a clinical setting

IViMOVA: In Vitro Maturation and vitrification of oocytes collected during OVarian cortex cryopreservation: a realistic fertility preservation therapy for trans men

Lab equipment necessary for the generation, manipulation and genome editing of pluripotent stem cells

Long-read sequencing for the detection of cryptic structural variation in patients with intellectual disability and congenital anomalies

long-read sequencing for the identification of structural rearrangements in patients with intellectual disability

New developments in Preimplantation Genetic Testing: towards noninvasive, comprehensive chromosome screening

Non-invasive prenatal screening for the presymptomatic detection of pregnancy complications

Precision medicine in inherited blindness using integrated omics in human and animal models

Sequencing Expertise Centre (Life Sciences)

The role of lncRNAs in human cognition

The role of long noncoding RNAs in human cognition

The role of long noncoding RNAs in human cognition

Unraveling the role of MYT1L in intellectual disability: an integrated functional genetic approach

Unraveling the role of the KEOPS complex in Galloway-Mowat syndrome

Application of the Nuclear Transfer technology to overcome female-related infertility

Characterization of novel genetic causes of combined OXPHOS deficiencies

Development and application of digital PCR

Human germline gene editing to overcome transmission of infertility: a proof-of-concept study

Identification of causal mutations in patients with unexplained mental retardation and congenital abnormalities by high throughput sequencing of selected candidate genes

Improving outcome of immune checkpoint blockade in lung cancer by combination with a tumor mutanome-targeted dendritic cell vaccine

Improving outcome of immune checkpoint blockade in lung cancer by combination with a tumor mutanome-targeted dendritic cell vaccine

IsoFlux System: Isolation of rare cells from biological samples

Nuclear Transfer for female-related infertility and mitochondrial diseases

Safety first: optimizing artificial oocyte creation through diploid cell haploidization

ThirdGenT: linking third-generation sequencing of (epi)genomes, (epi)transcriptomes and translatomes to life sciences revolutionizes oncology, rare diseases, microbiology, cell and gene technology, developmental and computational biology

BOF-ZAP professorship in neurogenetics

Fetal cell isolation and characterization for cell-based non-invasive prenatal genetic diagnosis

Immunomonitoring of patients with non-small cell lung carcinoma treated with a tumor mutanome-targeted dendritic cell vaccine

Proteomics-derived epitopes for dramatically improved anticancer and antibacterial vaccine development