Cofunding core facility - Animalarium,Radiological and Radiobiological Techniques, Histology Core

Uncaging the potential of photopharmacology for the treatment of epilepsy

Doctoral project Lars Emil Larsen

Doctoral project Leen De Taeye

Doctoral project Simona Manzella

Elucidation of neurological risks and associated pathways after early-life cranial radiotherapy.

Evaluation of multidrug adjunctive cancer treatment (MDACT) in glioblastoma

Noradrenergic modulation of seizures and epilepsy: the good, the bad and the ugly

The role of astrocytes in noradrenergic modulation of hippocampal excitability

Toward precision therapy for epilepsy: use of photoactivatable seizure-suppressing molecules for local treatment of seizure focus in an animal model of temporal lobe epilepsy.

Advanced brain network analysis for a better understanding of functional and structural brain network changes in post-stroke epilepsy

A miniature soft optrode for photopharmacological therapy towards epileptic seizure suppression

"Breaking Barriers” in Glioblastoma Treatment: Transcranial Focused Ultrasound and intra-carotid arterial administration to improve the efficacy of Targeted Radioligand Therapy

Computational Modeling of Optogenetic Neuromodulation and Neural Recording for Treatment of Temporal Lobe Epilepsy

Design and Development of a Flexible Electronic Subcutaneous Patch as Interface for Soft Electo-Optical Neuroprobes

Doctoral project Bram Vandekerckhove

Doctoral project Glynnis Devos

Doctoral project Jeroen Spanoghe

Doctoral project Lies Mollet

Doctoral project Melissa Lajtos

Doctoral project Nathalie Van Den Berge

Exploring the Therapeutic Potential of Vagus Nerve Stimulation in Multiple Sclerosis: Insights from Preclinical Models

Longitudinal Structural and Functional Brain Network Changes during Epileptogenesis in a Rat Model of Temporal Lobe Epilepsy

Modeling and design of a closed-loop neurostimulation platform for epilepsy treatment

Neuroprobe for Epilepsy treatment with Optogenetics

Optical modulation of neuronal excitability using a novel photocaged adenosine A1 receptor agonist and its application in an ex vivo seizure model

PHOTO-RESPONSIVE POLYMERS TO SERVE EPILEPSY TREATMENT

Rational design and synthesis of non-hallucinogenic psilocin analogues as selective 5-HT2A receptor agonists with therapeutic potential

Alliance Research Group: Modulation in Epilepsy

BOF-ZAP professorship in intracranial electrophysiology

Emotion control in patients with comorbidity of epilepsy and depression

Essential equipment for the Animal Facility core (part III): bedding disposal system.

Evaluating the potential of Multidrug Adjunctive Cancer Treatment (MDACT) in glioblastoma

Focal activation of adenosine A1 receptor signaling in the hippocampus by means of photopharmacology: a possible tool for epileptic seizure suppression

GlioSELECT - A multi-omic single-cell, functional precision oncology platform to guide personalised medicine in high-grade brain tumors

Individual ventilated cage system for the central animal facility of the faculty of Medicine and Health Sciences

New approaches for detection and modulation of abnormal brain networks in a preclinical model for epilepsy based on a combination of functional magnetic resonance imaging, optogenetics, chemogenetics and intracranial electroencephalography

Noradrenergic modulation of innate and adaptive immune responses: Role in pathogenesis and treatment of EAE

Noradrenergic modulation of seizures and epilepsy: the good, the bad and the ugly

Novel approaches for improving quality of life of children treated for brain tumors: focus on the noradrenergic system

Photoswitchable cannabinoids for precision treatment of refractory focal epileptic seizures

Preclinical evaluation of chemogenetics as new treatment for drug-resistant epilepsy

Preclinical research @ 4BRAIN

Soft and flexible technologies for electrical and optical modulation of the epileptic brain.

The role of the locus coeruleus noradrenergic system in seizures and epilepsy

Vagus nerve stimulation-induced neuroplasticity and its impact on the effectiveness of deep brain stimulation as a therapy for epilepsy

Water bottle handling system for the central animal facility of the Faculty of Medicine and Health Sciences

An investigation into an animal-friendly method for killing individual poultry

A patient derived xenograft (PDX) platform for in vivo evaluation of novel anticancer therapies

Basic research equipment for paraffin-based histology.

Development of technology for next generation closed-loop precision therapy for seizure control in epilepsy using photopharmacology and optogenetics

Elucidating the fundamental questions of deep brain stimulation in temporal lobe epilepsy: Where and How to stimulate?

Enhancing the effects of brain stimulation using targeted brain plasticity

Expanding the capabilities of laser ablation-single particle-ICP-mass spectrometry imaging to study in situ degradation of medical implants

New hydrogel-based, soft waveguides for optical neuromodulation

Preclinical evaluation of Vagus Nerve Stimulation as a therapeutic option in Multiple Sclerosis.

Rational design and synthesis of non-hallucinogenic psilocin analogues as selective 5-HT2A receptor agonists with therapeutic potential

Strategies for boosting local adenosine A1 signaling as a treatment for focal epilepsy: from positive allosteric modulators of the inhibitory A1 receptor to deep brain stimulation and photopharmacology.

Studying brain network changes in epilepsy by combining functional magnetic resonance imaging, intracranial electroencephalography and opto-/chemogenetics to unravel biomarkers for disease prognosis and efficacy of anti-epileptic treatments

The role of the locus coeruleus and hippocampal noradrenergic neurotransmission in the anticonvulsive effect of vagus nerve stimulation.

The role of the locus coeruleus noradrenergic neurons in the anticonvulsive effect of vagus nerve stimulation (VNS) in the intrahippocampal pilocarpine model.

Tissue and cell culture core facility

Transparent and hermetic feedthrough for chronically implantable soft optical and electrical neuroprobes

Upgrade of confocal FLIM microscope with two-photon excitation and detection modules

White light laser-based confocal fluorescence lifetime imaging microscope for multi-parameter 3D live imaging

BOF-ZAP professorship in intracranial electrophysiology