REpurposing lung Surfactant Protein B for Inhalation therapy with RNA therapeutics

A lipid nanoparticle platform for RNA delivery with cationic amphiphilic drugs: merging the best of both worlds.

Design of lipid nanoparticles for RNA-based ex vivo T cell engineering in cancer immunotherapy

Development and evaluation of nanoformulations for inhalation of RNA therapeutics

Development of lipid nanoparticles for inhalation of RNA therapeutics

Doctoral project Lore Herman

Exploring co-encapsulation of small molecules and immune checkpoint siRNAs in lipid nanoparticles for anti-cancer immunotherapy

Inhalable mRNA LNP formulations for treatment of lung pathologies

Strategies to overcome the lysosomal entrapment of siRNA therapeutics and chemotherapeutic drugs.

Doctoral project Arianna Oddo

Doctoral project Freya Joris

Doctoral project Jelter Van Hoeck

Doctoral project Laurens Raes

Doctoral project Lore Herman

Doctoral project Roberta Guagliardo

Doctoral project Stephan Stremersch

Doctoral project Thijs Van de Vyver

Exploring biochemical and biophysical methods for the delivery of biologics to the corneal epithelium.

Immunogenicity versus efficacy of lipid nanoparticle-mediated delivery of mRNA and self-amplifying mRNA to the retina.

mRNA lipid nanoparticles for ocular applications

Synthesis of modified PNA probes for sequence-selective G-quadruplex photoalkylation

Unfolding the versatility of laser-induced vapor nanobubbles: from balancing intracellular delivery with regulated cell death to loading of extracellular vesicles.

BOF-TT-professorship in biophysics of the administration of biological drugs

Combination cancer therapy by simultaneous delivery of cationic amphiphilic drugs and RNA therapeutics using a polymer delivery platform

Design and development of nucleic acid nanoformulations for therapeutic applications in the lung

Exploring co-encapsulation of antihistamines and immune checkpoint siRNAs in lipid nanoparticles for cancer immunotherapy.

Local immunomodulation of atherosclerosis by CD8+ T-cell based nanomedicines

NANOMED / Colloidally stable nanogel formulations for siRNA delivery

Repurposing lung surfactant protein B for inhalation therapy with RNA therapeutics

Repurposing of cationic amphiphilic drugs as adjuvants to enhance the cellular delivery of RNA therapeutics

RNA-MAGIC: RNA-based bioMArkers and tarGets In asthma and Chronic Obstructive Pulmonary Disease (COPD)

Conformationally locked G4-decoy oligonucleotides for selective telomerase inhibition and development of a nucleic acid-based anti-telomerase PROTAC strategy

Cytotoxic cell-mediated delivery of nucleic acid nanoparticles as a synergistic cancer immunotherapy

Exosome-inspired nanocarriers for the delivery of small interfering RNA

Laser bench for laser scanning confocal microscopy

Screening for molecular adjuvants to enhance cytoplasmic delivery of small interfering RNA in cancer cells

Stimulated emission depletion microscopy (STED): Nanoscopy for innovative research in the life sciences

Synthesis of modified PNA probes for sequence-selective G-quadruplex photoalkylation.

BOF-TT-professorship in biophysics of the administration of biological drugs

Evaluation of small interfering RNA delivery via nano-particle-laden cells tumoritrope

Pulmonary delivery of small RNAs