Project

Pulmonary delivery of small RNAs

Code

3E014010

Duration

01 October 2010 → 30 September 2016

Funding

Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)

Promotor

Stefaan De Smedt

Fellow

Koen Raemdonck

Research disciplines

Medical and health sciences
- Biomarker discovery and evaluation
- Drug discovery and development
- Medicinal products
- Pharmaceutics
- Pharmacognosy and phytochemistry
- Pharmacology
- Pharmacotherapy
- Toxicology and toxinology
- Other pharmaceutical sciences
Engineering and technology
- Chemical product design and formulation
- Biomaterials engineering

Keywords

drug delivery nanoparticle lungs miRNA siRNA

Project description

The research project describes the design of pulmonary delivery strategies for small RNAs (siRNA and miRNA) and their evaluation in several in vitro and in vivo therapeutic models. The presented project aims to investigate if an optimized formulation of small RNAs may provide a significant therapeutic benefit.