Project

RNA-MAGIC: RNA-based bioMArkers and tarGets In asthma and Chronic Obstructive Pulmonary Disease (COPD)

Acronym
RNA-MAGIC
Duration
01 January 2019 → Ongoing
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Respiratory medicine
    • Respiratory medicine
    • Respiratory medicine
Keywords
Asthma Chronic Obstructive Pulmonary Disease (COPD) RNA-biomarkers RNA-therapeutics
 
Project description

Through multidisciplinary collaboration within this interfaculty RNA-MAGIC consortium, we will discover novel prognostic and theragnostic RNA-based biomarkers in asthma and COPD. By combining transcriptional profiling of airway epithelial cells with CRISPR-interference and drug repurposing investigations, the consortium will identify novel therapeutic targets in asthma and COPD, validate these in vivo using translational approaches, and optimize RNA-based drug delivery via inhalation.