CleanChem

DiscoverE

DiscoverE

An Opportunity to Develop Novel Inhibitors of Invasion for the Treatment of Metastatic Cancers

Circumventing the Biological Obstacles of anti-inflammatory Glucocorticoid Therapy

Exploiting novel GR biology as an opportunity to develop safer anti-inflammatory drugs

Fighting infectious diseases with combination therapy: targetting sociomicrobiological processes to circumvent antimicrobial resistance

Hit-to-lead Evaluation of Chalcone Analogs Useful for Anti-Invasive Cancer Therapy

Increasing the value proposition of the IOF programs CRISParray and Amalus: CRISPRi-based target deconvolution of fibroblast modulators

Opportunity to develop novel HDAC6 inhibitors for therapeutic use

STOP_SEPSIS: investigation into a new concept of sepsis, the greatest unmet medical need of our times.

STRETCH: mechanotransduction in osteoimmunology: an innovative approach towards effective drug for rheumatic diseases

Targeting transcription factor addiction in acute leukemia (TaTFAL)

Unravelling the pharmaceutical potential of receptor heterodimers for therapeutic intervention in CNS disorders.

Accellerating towards clinical validation of Galsome nanovaccines

An innovative class of ionizable lipids for use in lipid nanoparticle based RNA therapeutics and vaccines

A SMART technology for the continuous manufacturing of lyophilized orally disintegrating tablets

BioGelator for local immunotherapy

Development of an innovative Fentanyl vaccine

DiscoverE

Evaluation of a new treatment against "blackhead" disease in turkeys (POULTRY 2)

Extending the Amalus drug discovery program: validation studies for immuno-oncological and fibrosis indications to increase the IP and investment value

Identification of optimized Aurora Kinase A PROTACs with suitable PK properties for in vivo proof-of-concept studies (OPTIMAPK).

Increasing the value proposition of the IOF programs CRISParray and Amalus: CRISPRi-based target deconvolution of fibroblast modulators

Introducing mRNA vaccination in chicken: first steps towards a commercial mRNA vaccine against a leading viral infection in chicken

IonKey/MSTM system: enhanced ‘plug and play’ mass spectrometry for ultrasensitive quantification of small molecules in small sample volumes in life sciences, with applications in the development and valorisation of endotoxin-mitigation strategies (feed additives) and anti-inflammatory drugs (pharma) in livestock.

IP strenghtening for MIDRIX, a unique manufacturing process for dendritic cell immunotherapy in solid cancers

Mechanistic & Empirical Modeling for the PHarmaceutical InduStry

Strengthening the UGent patent position on an improved cultivation method for adoptive cell therapies (immuno-oncology).

TARgeted Mrna re-engineering for enhanced Antibody and Cellular immunity (TARMAC)

The generation of bona fide T cell precursors for cell therapy

Validation of a small molecule system for a safer treatment of chronic inflammation