Accellerating towards clinical validation of Galsome nanovaccines

mRNA vaccin Galsomes
15 June 2020 → 28 February 2022
Regional and community funding: Industrial Research Fund
Research disciplines
  • Medical and health sciences
    • Drug discovery and development not elsewhere classified
    • Cancer therapy
Cancer vaccination nanomedicines cancer immunotherapy GMP production clinical translation
Project description

Although the Galsome mRNA vaccine platform has a broad application potential, we opt to first accelerate validation and valorization of Galsomes for treatment of solid tumors. The first objective is to accelerate the translation of Galsomes to a clinical-grade product. This in view of a phase Ia/b clinical trial in lung cancer patients. FThe second objective aims to address the market trend for targeting “neo-antigens” by validating neo-antigen-based Galsome vaccination in a highly relevant orthotopic lung cancer model. A third objective is to perform an in-depth market analysis to identify high-value clinical unmet needs that can be addressed by the Galsome technology and can offer competitive advantages over other commercially available platforms. Such business case may form the basis for a business plan and initial contacts with investors.