Human germline gene editing to overcome transmission of infertility: a proof-of-concept study

Nuclear Transfer for female-related infertility and mitochondrial diseases

Doctoral project Arantxa Cardona Barberán

Doctoral project Gwenny Cosemans

Doctoral project Haitang He

In vitro maturation of immature follicles: functional analysis and application of Nuclear Transfer technology

In vitro spermatogenesis in mice

Rejuvenation of oocytes to overcome infertility due to advanced maternal age

Scrutinizing the dynamics of lineage segregations in the early embryo via CRISPR/Cas9-mediated germline genome editing

The road to functional oocytes: in vitro gametogenesis versus haploidization

The use of Nuclear Transfer technology to overcome female-related infertility

Unraveling failed fertilization and embryonic development after ICSI

Use of Nuclear Transfer technology to overcome mitochondrial diseases and female-related infertility

Doctoral project Annelies Raes

Doctoral project Minerva Ferrer Buitrago

Doctoral project Sabitri Ghimire

Doctoral project Sharat Warrier

Exploring and optimizing of variant detection and phasing methods in pharmacogenomics.

Human germline gene editing to overcome transmission of infertility: a proof-of-concept study

Nuclear Transfer for female-related infertility and mitochondrial diseases

Regulation of human oocyte ageing

Advancing Fertility and Reproduction thrOugh Dedicated and Innovative Technological Applications

Application of the Nuclear Transfer technology to overcome female-related infertility

Cofunding Core Facility - Clinical Tissue and Cell Culture core

Comparison of editing, complementing or replacement of defective RNA molecules as a novel treatment method to overcome early embryonic developmental arrest

Ex ovo omnia: from stem cell to oocyte

From primordial follicles to mature oocytes: the entire human oogenesis in vitro

Novel approaches to prevent transmission of mitochondrial diseases: filling in the safety gaps towards clinical application

Restoring fertility by the 3R-approach : rejuvenating, replacing or reconstructing the oocyte

Safety first: optimizing artificial oocyte creation through diploid cell haploidization

Scrutinizing the dynamics of first lineage segregation in the embryo via CRISPR/Cas9-mediated germline genome editing

Unraveling early lineage segregation during human embryonic development using CRISPR-Cas9 gene editing

Unraveling human trophectoderm development with the use of CRISPR/Cas9

Unravelling early cell fate decisions during human preimplantation development

Unravelling the mitochondrial DNA reversion phenomenon

Confocal laser scanning microscopy for infertility and stem cell research

Investigation of the spermfactor phospholipase C zeta associated with failed fertilization

Manipulating cell fate during embryonic development and stem cell derivation

Naive human embryonic stem cells: the new contender?

Nuclear transfer technology for the prevention of mitochondrial diseases and infertility

Stepwise differentiation of naive pluripotent stem cells towards haploid sperm cells for infertile patients 

ThirdGenT: linking third-generation sequencing of (epi)genomes, (epi)transcriptomes and translatomes to life sciences revolutionizes oncology, rare diseases, microbiology, cell and gene technology, developmental and computational biology

Unraveling early lineage segregation during human embryonic development using CRISPR-Cas9 gene editing

Upgrade of confocal FLIM microscope with two-photon excitation and detection modules

White light laser-based confocal fluorescence lifetime imaging microscope for multi-parameter 3D live imaging

Bridging the gap in mitochondrial disorder diagnosis and treatment by using human embryos and pluripotent stem cells