Nuclear Transfer for female-related infertility and mitochondrial diseases

Application of the Nuclear Transfer technology to overcome female-related infertility

Clinical Tissue and Cell Culture core

Comparison of editing, complementing or replacement of defective RNA molecules as a novel treatment method to overcome early embryonic developmental arrest

Ex ovo omnia: from stem cell to oocyte

From primordial follicles to mature oocytes: the entire human oogenesis in vitro

Novel approaches to prevent transmission of mitochondrial diseases: filling in the safety gaps towards clinical application

Restoring fertility by the 3R-approach : rejuvenating, replacing or reconstructing the oocyte

Safety first: optimizing artificial oocyte creation through diploid cell haploidization

Unraveling early lineage segregation during human embryonic development using CRISPR-Cas9 gene editing

Unraveling human trophectoderm development with the use of CRISPR/Cas9

Unravelling early cell fate decisions during human preimplantation development

Unravelling the mitochondrial DNA reversion phenomenon

Confocal laser scanning microscopy for infertility and stem cell research

Investigation of the spermfactor phospholipase C zeta associated with failed fertilization

Manipulating cell fate during embryonic development and stem cell derivation

Naive human embryonic stem cells: the new contender?

Nuclear transfer technology for the prevention of mitochondrial diseases and infertility

Stepwise differentiation of naive pluripotent stem cells towards haploid sperm cells for infertile patients 

Unraveling early lineage segregation during human embryonic development using CRISPR-Cas9 gene editing

White light laser-based confocal fluorescence lifetime imaging microscope for multi-parameter 3D live imaging

Bridging the gap in mitochondrial disorder diagnosis and treatment by using human embryos and pluripotent stem cells