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Researcher
Björn Heindryckx
Profile
Projects
Publications
Activities
Awards & Distinctions
242
Results
2024
Attitude of Belgian women towards enucleated egg donation for treatment of mitochondrial diseases and infertility
Guido Pennings
Björn Heindryckx
Dominic Stoop
Heidi Mertes
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2024
Effect of biphasic CAPA-IVM on ovarian tissue oocytes of transgender men
Muhammad Fakhar-I-Adil
Antonia Christodoulaki
Susana Marina Chuva de Sousa Lopes
Steven Weyers
Björn Menten
Ann Van Soom
Dominic Stoop
Chloë De Roo
Björn Heindryckx
C3
Conference
2024
High rate of detected variants in male PLCZ1 and ACTL7A genes causing failed fertilization after ICSI
Arantxa Cardona Barberán
Ramesh Reddy Guggilla
Cora Colenbier
Emma Van der Velden
Andrei Rybouchkin
Dominic Stoop
Luc Leybaert
Paul Coucke
Sofie Symoens
Annekatrien Boel
et al.
A1
Journal Article
in
HUMAN REPRODUCTION OPEN
2024
Pronuclear transfer rescues poor embryo development of in vitro-grown secondary mouse follicles
Antonia Christodoulaki
Haitang He
Min Zhou
Chloë De Roo
Machteld Baetens
Tine De Pretre
Muhammad Fakhar-I-Adil
Björn Menten
Ann Van Soom
Dominic Stoop
et al.
A1
Journal Article
in
HUMAN REPRODUCTION OPEN
2024
2023
Assisted oocyte activation does not overcome recurrent embryo developmental problems
Arantxa Cardona Barberán
Davina Bonte
Annekatrien Boel
Vanessa Thys
Ruth Paredis
Femke Machtelinckx
Petra De Sutter
Ilse De Croo
Luc Leybaert
Dominic Stoop
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2023
CRISPR/Cas9-based correction of infertility-related mutations in the germline : ready or not?
Bieke Bekaert
Björn Heindryckx
Annekatrien Boel
Björn Menten
Dissertation
2023
Cathepsin-L secreted by high-quality bovine embryos exerts an embryotrophic effect in vitro
Annelies Raes
Eline Wydooghe
Krishna Chaitanya Pavani
Osvaldo Américo Bogado Pascottini
Katleen Van Steendam
Maarten Dhaenens
Annekatrien Boel
Sonia Heras
Björn Heindryckx
Luc Peelman
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023
Characterization of ovarian tissue oocytes from transgender men reveals poor calcium release and embryo development, which might be overcome by spindle transfer
Antonia Christodoulaki
Haitang He
Min Zhou
Arantxa Cardona Barberán
Chloë De Roo
Susana Marina Chuva de Sousa Lopes
Machteld Baetens
Björn Menten
Ann Van Soom
Petra De Sutter
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2023
Effect of biphasic CAPA-IVM on ovarian tissue oocytes of transgender men
Muhammad Fakhar-I-Adil
Antonia Christodoulaki
Annekatrien Boel
Susana Marina Chuva de Sousa Lopes
Björn Menten
Ann Van Soom
Dominic Stoop
Chloë De Roo
Björn Heindryckx
C3
Conference
2023
Germline nuclear transfer to overcome oocyte cytoplasmic immaturity of in vitro matured oocytes
Antonia Christodoulaki
Björn Heindryckx
Dominic Stoop
Dissertation
2023
Monogenic and digenic variants in male PLCZ1, ACTL7A and ACTL9 genes cause fertilization failure after ICSI
Arantxa Cardona Barberán
Annekatrien Boel
Cora Colenbier
Emma Van der Velden
Dominic Stoop
Paul Coucke
Frauke Vanden Meerschaut
Björn Heindryckx
C3
Conference
2023
Nuclear transfer overcomes poor embryo development of in vitro grown mouse oocytes
Antonia Christodoulaki
H. He
M. Zhou
C. De Roo
M. Baetens
Björn Menten
Ann Van Soom
Dominic Stoop
A. Boel
Björn Heindryckx
C3
Conference
2023
Reliability of blastomere versus trophectoderm biopsy in preimplantation genetic testing for mitochondrial DNA disorders
Noemi Castelluccio
Ramesh Reddy Guggilla
Andrei Rybouchkin
Dominic Stoop
Sofie Symoens
Paul Coucke
Annekatrien Boel
Björn Heindryckx
C3
Conference
2023
Retained chromosomal integrity following CRISPR-Cas9-based mutational correction in human embryos
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Winter Vandenberghe
Mina Popovic
Panagiotis Stamatiadis
Gwenny Cosemans
Lise Tordeurs
Athina-Maria De Loore
Susana Marina Chuva de Sousa Lopes
et al.
A1
Journal Article
in
MOLECULAR THERAPY
2023
The ovaries under supraphysiological androgen exposure
Antonia Christodoulaki
Chloë De Roo
Björn Heindryckx
Dominic Stoop
Bookchapter
in
Context, principles and practice of transgynecology : managing transgender patients in ob/gyn practice
2023
2022
A CRISPR-view on the molecular mechanisms regulating mouse and human preimplantation embryo development
Panagiotis Stamatiadis
Björn Heindryckx
Petra De Sutter
Dissertation
2022
CRISPR/Cas gene editing in the human germline
Bieke Bekaert
Annekatrien Boel
Gwenny Cosemans
Lisa De Witte
Björn Menten
Björn Heindryckx
A1
Journal Article
in
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
2022
Distinct genetic impact of CRISPR/Cas9 gene correction in human embryos compared to induced pluripotent stem cells
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Gwenny Cosemans
Lise Tordeurs
Athina-Maria De Loore
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
Dominic Stoop
Paul Coucke
et al.
C3
Conference
2022
Evaluation of CRISPR/Cas9-induced DNA break repair outcomes in mouse and human embryos
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Gwenny Cosemans
Susana Marina Chuva de Sousa Lopes
Björn Menten
Björn Heindryckx
C3
Conference
2022
Exploring and optimizing variant detection and phasing methods in pharmacogenomics
Laurentijn Tilleman
Filip Van Nieuwerburgh
Björn Heindryckx
Dieter Deforce
Dissertation
2022
Fertilization failure after human ICSI and the clinical potential of PLCZ1
Arantxa Cardona Barberán
Annekatrien Boel
Frauke Vanden Meerschaut
Dominic Stoop
Björn Heindryckx
A1
Journal Article
in
REPRODUCTION
2022
Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts
Krishna Chaitanya Pavani
Tim Meese
Osvaldo Américo Bogado Pascottini
XueFeng Guan
Xiaoyuan Lin
Luc Peelman
Joachim Hamacher
Filip Van Nieuwerburgh
Dieter Deforce
Annekatrien Boel
et al.
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2022
Human germline nuclear transfer to overcome mitochondrial disease and failed fertilization after ICSI
Maoxing Tang
Annekatrien Boel
Noemi Castelluccio
Arantxa Cardona Barberán
Antonia Christodoulaki
Bieke Bekaert
Mina Popovic
Frauke Vanden Meerschaut
Petra De Sutter
Björn Menten
et al.
A1
Journal Article
in
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
2022
Spindle transfer rescues poor embryo development of in vitro matured ovarian tissue oocytes from transgender men
Antonia Christodoulaki
H. He
M. Zhou
Arantxa Cardona Barberán
Chloë De Roo
S. M. Chuva De Sousa Lopes
Björn Menten
Ann Van Soom
Petra De Sutter
Annekatrien Boel
et al.
C3
Conference
2022
TEAD4 regulates trophectoderm differentiation upstream of CDX2 in a GATA3-independent manner in the human preimplantation embryo
Panagiotis Stamatiadis
Gwenny Cosemans
Annekatrien Boel
Björn Menten
Petra De Sutter
Dominic Stoop
Susana Marina Chuva de Sousa Lopes
Frederic Lluis
Paul Coucke
Björn Heindryckx
A1
Journal Article
in
HUMAN REPRODUCTION
2022
Treatment options to overcome impaired fertilization and embryonic development caused by an oocyte-related deficiency in the Patl2-/- mouse model
Arantxa Cardona Barberán
Antonia Christodoulaki
Josefien Goethals
Vanessa Thys
Frauke Vanden Meerschaut
C. Arnoult
Dominic Stoop
Annekatrien Boel
Björn Heindryckx
C3
Conference
2022
2021
Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells
Swati Mishra
Jasin Taelman
Mina Popovic
Laurentijn Tilleman
Evi Duthoo
Margot Van der Jeught
Dieter Deforce
Filip Van Nieuwerburgh
Björn Menten
Petra De Sutter
et al.
A1
Journal Article
in
STEM CELLS
2021
Calcium analysis and embryonic development of in vitro matured oocytes from transgender men
Antonia Christodoulaki
Haitang He
Arantxa Cardona Barberán
Chloë De Roo
Susana Marina Chuva de Sousa Lopes
Björn Menten
Ann Van Soom
Petra De Sutter
Dominic Stoop
Annekatrien Boel
et al.
C3
Conference
2021
Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences
Panagiotis Stamatiadis
Annekatrien Boel
Gwenny Cosemans
Mina Popovic
Bieke Bekaert
Ramesh Reddy Guggilla
Maoxing Tang
Petra De Sutter
Filip Van Nieuwerburgh
Björn Menten
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2021
Correcting a PLCζ mutation in the human germ line to overcome hereditary infertility
Bieke Bekaert
Annekatrien Boel
Mina Popovic
Panagiotis Stamatiadis
S M Chuva de Sousa Lopes
Petra De Sutter
Björn Menten
Dominic Stoop
Paul Coucke
Björn Heindryckx
C3
Conference
2021
Digital polymerase chain reaction for assessment of mutant mitochondrial carry-over after nuclear transfer for In Vitro fertilization
Olivier Tytgat
MX Tang
Willem van Snippenberg
Annekatrien Boel
RR Guggilla
Yannick Gansemans
Michiel Van Herp
Sofie Symoens
Wim Trypsteen
Dieter Deforce
et al.
A1
Journal Article
in
CLINICAL CHEMISTRY
2021
Digital polymerase chain reaction for assessment of mutant mitochondrial carry-over after nuclear transfer for in vitro fertilization
Olivier Tytgat
Maoxing Tang
Willem van Snippenberg
Annekatrien Boel
Ramesh Reddy Guggilla
Yannick Gansemans
Michiel Van Herp
Sofie Symoens
Wim Trypsteen
Dieter Deforce
et al.
A1
Journal Article
in
CLINICAL CHEMISTRY
2021
Prospects of germline nuclear transfer in women with diminished ovarian reserve
Antonia Christodoulaki
Annekatrien Boel
Maoxing Tang
Chloë De Roo
Dominic Stoop
Björn Heindryckx
A1
Journal Article
in
FRONTIERS IN ENDOCRINOLOGY
2021
Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions
Liselot Mus
Stéphane Van Haver
Mina Popovic
Wim Trypsteen
Steve Lefever
Nadja Zeltner
Yudelca Ogando
Eva Jacobs
Geertrui Denecker
Ellen Sanders
et al.
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2021
Sex-specific isolation and propagation of human premeiotic fetal germ cells and germ cell-like cells
Swati Mishra
Jasin Taelman
Yolanda W. Chang
Annekatrien Boel
Petra De Sutter
Björn Heindryckx
Susana Marina Chuva de Sousa Lopes
A1
Journal Article
in
CELLS
2021
Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development
Maya Sen
Dylan Mooijman
Alex Chialastri
Jean-Charles Boisset
Mina Popovic
Björn Heindryckx
Susana Marina Chuva de Sousa Lopes
Siddharth S. Dey
Alexander van Oudenaarden
A1
Journal Article
in
NATURE COMMUNICATIONS
2021
2020
A proof-of-concept study to investigate DNA repair mechanisms in the human embryo after the application of CRISPR/Cas9 gene editing in the germ line
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Mina Popovic
Ramesh Reddy Guggilla
Swati Mishra
Gwenny Cosemans
Lise Tordeurs
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
et al.
C3
Conference
2020
Assessment of molecular determinants underlying recurrent embryo developmental arrest and value of assisted oocyte activation as a treatment option
Annekatrien Boel
Davina Bonte
Arantxa Cardona Barberán
Vanessa Thys
Dominic Stoop
Petra De Sutter
Paul Coucke
Frauke Vanden Meerschaut
Björn Heindryckx
C3
Conference
2020
Chromosomal mosaicism in human blastocysts : the ultimate diagnostic dilemma
Mina Popovic
Lien Dhaenens
Annekatrien Boel
Björn Menten
Björn Heindryckx
A1
Journal Article
in
HUMAN REPRODUCTION UPDATE
2020
Chromosomal mosaicism in human blastocysts : the ultimate diagnostic dilemma (vol 26, pg 313, 2020)
Mina Popovic
Lien Dhaenens
Annekatrien Boel
Björn Menten
Björn Heindryckx
Correction
2020
Comparative study of preimplantation development following distinct assisted oocyte activation protocols in a PLC-zeta knockout mouse model
Minerva Ferrer Buitrago
Laurentijn Tilleman
Vanessa Thys
A Hachem
Annekatrien Boel
Filip Van Nieuwerburgh
Dieter Deforce
Luc Leybaert
Petra De Sutter
J. Parrington
et al.
A1
Journal Article
in
MOLECULAR HUMAN REPRODUCTION
2020
Correcting PLCζ mutation in the germ line to overcome transmission of hereditary infertility in mice
Bieke Bekaert
Annekatrien Boel
Vanessa Thys
Panagiotis Stamatiadis
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
John Parrington
Björn Menten
Dominic Stoop
Paul Coucke
et al.
C3
Conference
2020
Correcting a PLCζ mutation in the human germ line to overcome hereditary infertility
Bieke Bekaert
Annekatrien Boel
Mina Popovic
Panagiotis Stamatiadis
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
Paul Coucke
Björn Heindryckx
C3
Conference
2020
Diagnosis and treatment of male infertility-related fertilization failure
Arantxa Cardona Barberán
Annekatrien Boel
Frauke Vanden Meerschaut
Dominic Stoop
Björn Heindryckx
A1
Journal Article
in
JOURNAL OF CLINICAL MEDICINE
2020
Germline nuclear transfer in mice may rescue poor embryo development associated with advanced maternal age and early embryo arrest
Maoxing Tang
Mina Popovic
Panagiotis Stamatiadis
Margot Van der Jeught
Rudy Van Coster
Dieter Deforce
Petra De Sutter
Paul Coucke
Björn Menten
Dominic Stoop
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2020
Germline nuclear transfer to overcome mitochondrial diseases and female infertility
Maoxing Tang
Björn Heindryckx
Petra De Sutter
Dissertation
2020
Modelling human embryogenesis : embryo-like structures spark ethical and policy debate
AM Pereira Daoud
Mina Popovic
WJ Dondorp
M Trani Bustos
AL Bredenoord
Susana Marina Chuva de Sousa Lopes
SC van den Brink
Roelen BAJ
de Wert GMWR
Björn Heindryckx
A1
Journal Article
in
HUMAN REPRODUCTION UPDATE
2020
Pan-cancer pharmacogenetics : targeted sequencing panels or exome sequencing?
Laurentijn Tilleman
Björn Heindryckx
Dieter Deforce
Filip Van Nieuwerburgh
A1
Journal Article
in
PHARMACOGENOMICS
2020
Vitrification negatively affects the Ca2+-releasing and activation potential of mouse oocytes, but vitrified oocytes are potentially useful for diagnostic purposes
Davina Bonte
Vanessa Thys
Petra De Sutter
Annekatrien Boel
Luc Leybaert
Björn Heindryckx
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2020
2019
17q gain provides proliferative advantage to human embryonic stem cells under conditions of replicative stress
Liselot Mus
Geertrui Denecker
Stéphane Van Haver
Nadja Zeltner
Yudelca Ogando
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conference
2019
17q gain provides proliferative advantage to human embryonic stem cells under replicative stress
Liselot Mus
Stéphane Van Haver
Geertrui Denecker
Nadja Zeltner
Yudelca Ogando
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conference
2019
Assessment of the calcium releasing machinery in oocytes that failed to fertilize after conventional ICSI and assisted oocyte activation
Minerva Ferrer Buitrago
Davina Bonte
Lien Dhaenens
Sanne Vermorgen
Yuechao Lu
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2019
Assisted oocyte activation significantly increases fertilization and pregnancy outcome in patients with low and total failed fertilization after intracytoplasmic sperm injection : a 17-year retrospective study
Davina Bonte
Minerva Ferrer Buitrago
Lien Dhaenens
Mina Popovic
Vanessa Thys
Ilse De Croo
Stefanie De Gheselle
Nathalie Steyaert
Annekatrien Boel
Frauke Vanden Meerschaut
et al.
A1
Journal Article
in
FERTILITY AND STERILITY
2019
Bta-miR-10b secreted by bovine embryos negatively impacts preimplantation embryo quality
Xiaoyuan Lin
Krishna Chaitanya Pavani
Katrien Smits
Dieter Deforce
Björn Heindryckx
Ann Van Soom
Luc Peelman
A1
Journal Article
in
FRONTIERS IN GENETICS
2019
Comparative analysis of different nuclear transfer techniques to prevent the transmission of mitochondrial DNA variants
Maoxing Tang
Ramesh Reddy Guggilla
Yannick Gansemans
Margot Van der Jeught
Annekatrien Boel
Mina Popovic
Panagiotis Stamatiadis
Minerva Ferrer Buitrago
Vanessa Thys
Rudy Van Coster
et al.
A1
Journal Article
in
MOLECULAR HUMAN REPRODUCTION
2019
Comparative analysis of different nuclear transfer techniques to prevent the transmission of mitochondrial DNA variants
Maoxing Tang
R Reddy
Yannick Gansemans
Margot Van der Jeught
Annekatrien Boel
Panagiotis Stamatiadis
Rudy Van Coster
Dieter Deforce
Filip Van Nieuwerburgh
Petra De Sutter
et al.
C3
Conference
2019
Contemporary pharmacogenetic assays in view of the PharmGKB database
Laurentijn Tilleman
Jana Weymaere
Björn Heindryckx
Dieter Deforce
Filip Van Nieuwerburgh
A1
Journal Article
in
PHARMACOGENOMICS
2019
Exploring the contribution of gene dosage effects of 17q gain genes on hESC and neuroblastoma proliferation
Liselot Mus
Geertrui Denecker
Stéphane Van Haver
Nadja Zeltner
Yudelca Ogando
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conference
2019
Extended in vitro culture of human embryos demonstrates the complex nature of diagnosing chromosomal mosaicism from a single trophectoderm biopsy
Mina Popovic
L. Dhaenens
J. Taelman
Annelies Dheedene
M. Bialecka
Petra De Sutter
S. M. Chuva de Sousa Lopes
Björn Menten
Björn Heindryckx
A1
Journal Article
in
HUMAN REPRODUCTION
2019
Human blastocyst outgrowths recapitulate primordial germ cell specification events
Mina Popovic
Monika Bialecka
Maria Gomes Fernandes
Jasin Taelman
Margot Van der Jeught
Petra De Sutter
Björn Heindryckx
Susana Marina Chuva de Sousa Lopes
A1
Journal Article
in
MOLECULAR HUMAN REPRODUCTION
2019
Increased primordial germ cell (PGC) specification from human embryonic stem cells (hESC) derived in Activin A
Swati Mishra
Margot Van der Jeught
Mina Popovic
Jasin Taelman
Evi Duthoo
Katarzyna Szymańska-Vandendriessche
Petra De Sutter
Laurentijn Tilleman
Filip Van Nieuwerburgh
Annekatrien Boel
et al.
C3
Conference
2019
Intracellular localisation of platelet-activating factor during mammalian embryo development in vitro : a comparison of cattle, mouse and human
Lynn Vandenberghe
Björn Heindryckx
Katrien Smits
Mina Popovic
Katarzyna Szymańska-Vandendriessche
Davina Bonte
Luc Peelman
Dieter Deforce
Petra De Sutter
Ann Van Soom
et al.
A1
Journal Article
in
REPRODUCTION FERTILITY AND DEVELOPMENT
2019
Losing balance : investigating the prevalence and impact of chromosomal instability during early human development
Mina Popovic
Björn Heindryckx
Petra De Sutter
Dissertation
2019
Robust protocol for feeder-free adaptation of cryopreserved human pluripotent stem cells
Jeffrey Aalders
Natasja Van den Vreken
Mina Popovic
Swati Mishra
Björn Heindryckx
Jolanda van Hengel
A1
Journal Article
in
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
2019
The importance of calcium : the quest for optimal diagnosis and treatment for fertilization failure and embryo arrest in human
Davina Bonte
Björn Heindryckx
Petra De Sutter
Dissertation
2019
The use of pronuclear transfer to overcome infertility disorders in mice
Björn Heindryckx
Annekatrien Boel
Panagiotis Stamatiadis
Margot Van der Jeught
Ramesh Reddy Guggilla
Dieter Deforce
Rudy Van Coster
Petra De Sutter
C3
Conference
2019
Two decades of embryonic stem cells : a historical overview
Cristina Eguizabal
Begoña Aran
Susana Marina Chuva de Sousa Lopes
M. Geens
Björn Heindryckx
S. Panula
Mina Popovic
Rita Vassena
Anna Veiga
A1
Journal Article
in
HUMAN REPRODUCTION OPEN
2019
Untargeted histone profiling during naive conversion uncovers conserved modification markers between mouse and human
Laura De Clerck
Jasin Taelman
Mina Popovic
Sander Willems
Margot Van der Jeught
Björn Heindryckx
Petra De Sutter
Hendrik Marks
Dieter Deforce
Maarten Dhaenens
A1
Journal Article
in
SCIENTIFIC REPORTS
2019
WNT inhibition and increased fibroblast growth factor signaling promotes derivation of less heterogeneous primed human embryonic stem cells, compatible with differentiation
Jasin Taelman
Mina Popovic
Monika Bialecka
Laurentijn Tilleman
Sharat Warrier
Margot Van der Jeught
Björn Menten
Dieter Deforce
Petra De Sutter
Filip Van Nieuwerburgh
et al.
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2019
2018
Assisted oocyte activation significantly increases fertilization and pregnancy rates resulting in healthy live births in patients with oocyte activation deficiencies
Davina Bonte
Lien Dhaenens
Minerva Ferrer Buitrago
Stefanie De Gheselle
Ilse De Croo
Petra De Sutter
Björn Heindryckx
C3
Conference
2018
CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells
Eva Jacobs
Sharat Warrier
Pieter-Jan Volders
Eva D'haene
Eva Vanlombergen
Lies Vantomme
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conference
2018
CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells
Eva Jacobs
Sharat Warrier
Pieter-Jan Volders
Eva D'haene
Eva Vanlombergen
Lies Vantomme
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conference
2018
Chromosomal mosaicism in human blastocysts : the ultimate challenge of preimplantation genetic testing?
Mina Popovic
Annelies Dheedene
CHRISTODOULOS CHRISTODOULOU
Jasin Taelman
Lien Dhaenens
Filip Van Nieuwerburgh
Dieter Deforce
Etienne Van den Abbeel
Petra De Sutter
Björn Menten
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2018
Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background
Sabitri Ghimire
Margot Van der Jeught
Jitesh Neupane
Matthias S Roost
Jasper Anckaert
Mina Popovic
Filip Van Nieuwerburgh
Pieter Mestdagh
Jo Vandesompele
Dieter Deforce
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2018
Culture conditions affect Ca2+ release in artificially activated mouse and human oocytes
Yuechao Lu
Davina Bonte
Minerva Ferrer Buitrago
Mina Popovic
Jitesh Neupane
Margot Van der Jeught
Luc Leybaert
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
REPRODUCTION FERTILITY AND DEVELOPMENT
2018
Deciphering the origin of human embryonic stem cells and different pluripotency states
Sharat Warrier
Petra De Sutter
Björn Heindryckx
Dissertation
2018
Diagnosis and treatment of oocyte activation deficiency in assisted reproduction technology
Minerva Ferrer Buitrago
Petra De Sutter
Björn Heindryckx
Dissertation
2018
Exploring the contribution of gene dosage effects of 17Q gain on ESC and neuroblastoma proliferation
Liselot Mus
Geertrui Denecker
Nadja Zeltner
Yudelca Ogando
Stéphane Van Haver
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conference
2018
Exploring the contribution of gene dosage effects of 17q gain genes on hESC and neuroblastoma proliferation
Liselot Mus
Geertrui Denecker
Stéphane Van Haver
Nadja Zeltner
Yudelca Ogando
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conference
2018
Exploring the contribution of gene dosage effects of 17q gain on ESC and neuroblastoma proliferation
Liselot Mus
Geertrui Denecker
Nadja Zeltner
Yudelca Ogando
Stéphane Van Haver
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conference
2018
Exploring the contribution of gene dosage effects of 17q gain on ESC and neuroblastoma proliferation
Liselot Mus
Geertrui Denecker
Nadja Zeltner
Yudelca Ogando
Stéphane Van Haver
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conference
2018
Human germline gene editing : recommendations of ESHG and ESHRE
Guido de Wert
Guido Pennings
Angus Clarke
Ursula Eichenlaub-Ritter
Carla G van El
Francesca Forzano
Mariëtte Goddijn
Björn Heindryckx
Heidi C Howard
Dragica Radojkovic
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2018
Human germline gene editing : recommendations of ESHG and ESHRE
Guido de Wert
Guido Pennings
Angus Clarke
Ursula Eichenlaub-Ritter
Carla G van El
Francesca Forzano
Mariëtte Goddijn
Björn Heindryckx
Heidi C Howard
Dragica Radojkovic
et al.
A1
Journal Article
in
HUMAN REPRODUCTION OPEN
2018
Human in vitro spermatogenesis from pluripotent stem cells : in need of a stepwise differentiation protocol?
C Rombaut
Heidi Mertes
Björn Heindryckx
E Goossens
A1
Journal Article
in
MOLECULAR HUMAN REPRODUCTION
2018
Human oocyte calcium analysis predicts the response to assisted oocyte activation in patients experiencing fertilization failure after ICSI
Minerva Ferrer Buitrago
Lien Dhaenens
Yuechao Lu
Davina Bonte
Frauke Vanden Meerschaut
Petra De Sutter
Luc Leybaert
Björn Heindryckx
A1
Journal Article
in
HUMAN REPRODUCTION
2018
Impact of pluripotency state and Activin A supplementation on derivation of primordial germ cell-like cells from human
Swati Mishra
Margot Van der Jeught
Jasin Taelman
Mina Popovic
Katarzyna Szymańska-Vandendriessche
Dieter Deforce
Petra De Sutter
Susana Marina Chuva de Sousa Lopes
Björn Heindryckx
C3
Conference
2018
Onderzoek op menselijke embryo’s in België : een overzicht
Guido Pennings
Seppe Segers
Sophie Debrock
Björn Heindryckx
Velichka Kontozova-Deutsch
Usha Punjabi
Hilde vande Velde
André van Steirteghem
Heidi Mertes
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2018
PLCz knock-out sperm reveals the sole effect of altering calcium signals during assisted oocyte activation on later mouse embryogenesis
Minerva Ferrer Buitrago
Laurentijn Tilleman
Vanessa Thys
A Hachem
Filip Van Nieuwerburgh
Luc Leybaert
Petra De Sutter
Dieter Deforce
J Parrington
Björn Heindryckx
C3
Conference
2018
Patients with a high proportion of immature and meiotically resistant oocytes experience defective nuclear oocyte maturation patterns and impaired pregnancy outcomes
Yuechao Lu
Minerva Ferrer Buitrago
Mina Popovic
Jitesh Neupane
Winnok De Vos
Sylvie Lierman
Etienne Van den Abbeel
Margot Van der Jeught
Dimitra Nikiforaki
Petra De Sutter
et al.
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2018
Platelet-activating factor acetylhydrolase 1B3 (PAFAH1 B3) is required for the formation of the meiotic spindle during in vitro oocyte maturation
Lynn Vandenberghe
Björn Heindryckx
Katrien Smits
Katarzyna Szymańska-Vandendriessche
Nerea Ortiz Escribano
Minerva Ferrer Buitrago
Krishna Chaitanya Pavani
Luc Peelman
Dieter Deforce
Petra De Sutter
et al.
A1
Journal Article
in
REPRODUCTION FERTILITY AND DEVELOPMENT
2018
Responsible innovation in human germline gene editing : background document to the recommendations of ESHG and ESHR
Guido de Wert
Björn Heindryckx
Guido Pennings
Angus Clarke
Ursula Eichenlaub-Ritter
Carla G van El
Francesca Forzano
Mariëtte Goddijn
Heidi C Howard
Dragica Radojkovic
et al.
A1
Journal Article
in
HUMAN REPRODUCTION OPEN
2018
Responsible innovation in human germline gene editing : background document to the recommendations of ESHG and ESHRE
Guido De Wert
Björn Heindryckx
Guido Pennings
Angus Clarke
Ursula Eichenlaub-Ritter
Carla G van El
Francesca Forzano
Mariëtte Goddijn
Heidi C Howard
Dragica Radojkovic
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2018
Robust protocol for feeder-free adaptation of frozen pluripotent stem cells using StemFlex
Jeffrey Aalders
Natasja Van den Vreken
Björn Heindryckx
Jolanda van Hengel
C3
Conference
2018
Single Ca2+ transients vs oscillatory Ca2+ signaling for assisted oocyte activation : limitations and benefits
Minerva Ferrer Buitrago
Davina Bonte
Petra De Sutter
Luc Leybaert
Björn Heindryckx
A1
Journal Article
in
REPRODUCTION
2018
Stem cell-derived spermatozoa
Jasin Taelman
Swati Mishra
Margot Van der Jeught
Björn Heindryckx
Bookchapter
in
Reproductomics : the -omics revolution and its impact on human reproductive medicine
2018
Strontium fails to induce Ca2+ release and activation in human oocytes despite the presence of functional TRPV3 channels
Y Lu
R Reddy
Minerva Ferrer Buitrago
Margot Van der Jeught
Jitesh Neupane
Winnok De Vos
Etienne Van den Abbeel
Sylvie Lierman
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
HUMAN REPRODUCTION OPEN
2018
The role of the reprogramming method and pluripotency state in gamete differentiation from patient-specific human pluripotent stem cells
Swati Mishra
E Kacin
Panagiotis Stamatiadis
S Franck
Margot Van der Jeught
Heidi Mertes
Guido Pennings
Petra De Sutter
K Sermon
Björn Heindryckx
et al.
A1
Journal Article
in
MOLECULAR HUMAN REPRODUCTION
2018
The use of vitrified-thawed mouse oocytes and lysolecithin to determine the oocyte activation potential of human sperm by Ca2+ pattern analysis
Davina Bonte
Vanessa Thys
Luc Leybaert
Petra De Sutter
Björn Heindryckx
C3
Conference
2018
Transcriptional landscape changes during human embryonic stem cell derivation
Sharat Warrier
Jasin Taelman
Laurentijn Tilleman
Margot Van der Jeught
Galbha Duggal
Sylvie Lierman
Mina Popovic
Ann Van Soom
Luc Peelman
Filip Van Nieuwerburgh
et al.
A1
Journal Article
in
MOLECULAR HUMAN REPRODUCTION
2018
Unraveling the causes of failed fertilization after intracytoplasmic sperm injection due to oocyte activation deficiency
Davina Bonte
Ramesh Reddy Guggilla
Panagiotis Stamatiadis
Petra De Sutter
Björn Heindryckx
Bookchapter
in
Reproductomics : the -omics revolution and its impact on human reproductive medicine
2018
Unravelling the molecular pathways responsible for sex determination in humans
Jasin Taelman
Mina Popovic
Laurentijn Tilleman
Margot Van der Jeught
Dieter Deforce
Petra De Sutter
Filip Van Nieuwerburgh
Björn Heindryckx
S Chuva De Sousa Lopes
C3
Conference
2018
Using vitrified mouse oocytes and lysolecithin to evaluate the oocyte-activating potential of human sperm by Ca2+ pattern analysis
Davina Bonte
Vanessa Thys
Luc Leybaert
Petra De Sutter
Björn Heindryckx
C3
Conference
2018
2017
CRISPR/Cas9-mediated genome editing in naive human embryonic stem cells followed by neural differentiation : an optimized workflow
Eva Jacobs
Sharrat Warrier
Eva D'haene
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conference
2017
CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells
Eva Jacobs
Sharat Warrier
Pieter-Jan Volders
Eva D'haene
Eva Van Lombergen
Lies Vantomme
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
A1
Journal Article
in
SCIENTIFIC REPORTS
2017
Can vitrified-thawed mouse oocytes be efficiently used to determine the oocyte activation potential of human sperm?
Davina Bonte
Minerva Ferrer Buitrago
Vanessa Thys
Dieter Deforce
Luc Leybaert
Petra De Sutter
Björn Heindryckx
C3
Conference
2017
Comprehensive comparison of inner cell mass and trophectoderm reveals the complex nature of chromosomal mosaicism in human embryos
Mina Popovic
Annelies Dheedene
CHRISTODOULOS CHRISTODOULOU
Margot Van der Jeught
Filip Van Nieuwerburgh
Dieter Deforce
Petra De Sutter
Etienne Van den Abbeel
Björn Menten
Björn Heindryckx
C3
Conference
2017
Direct comparison of distinct naive pluripotent states in human embryonic stem cells
Sharat Warrier
Margot Van der Jeught
Galbha Duggal
Laurentijn Tilleman
Ella Sutherland
Jasin Taelman
Mina Popovic
Sylvie Lierman
Susana Marina Chuva de Sousa Lopes
Ann Van Soom
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2017
Human embryo research in Belgium : an overview
Guido Pennings
Seppe Segers
Sophie Debrock
Björn Heindryckx
Velichka Kontozova-Deutsch
Usha Punjabi
Hilde vande Velde
André van Steirteghem
Heidi Mertes
A1
Journal Article
in
FERTILITY AND STERILITY
2017
Metabolic plasticity complements the unique nature and demands of distinct pluripotency states
Mina Popovic
Björn Heindryckx
Other
2017
Novel reproductive technologies to prevent mitochondrial disease
Lyndsey Craven
Maoxing Tang
Grainne S Gorman
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
HUMAN REPRODUCTION UPDATE
2017
Origins of human embryonic stem cell fate : role of the post inner cell mass intermediate
Sharat Warrier
Mina Popovic
Jasin Taelman
Laurentijn Tilleman
Sylvie Lierman
Minerva Ferrer Buitrago
S. Chuva De Sousa Lopes
Ann Van Soom
Luc Peelman
Filip Van Nieuwerburgh
et al.
C3
Conference
2017
PLCζ is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence
Alaa Hachem
Jonathan Godwin
Margarida Ruas
Hoi Chang Lee
Minerva Ferrer Buitrago
Goli Ardestani
Andrew Bassett
Sebastian Fox
Felipe Navarrete
Petra De Sutter
et al.
A1
Journal Article
in
DEVELOPMENT
2017
Preimplantation genetic diagnosis for chromosomal rearrangements with the use of array comparative genomic hybridization at the blastocyst stage
CHRISTODOULOS CHRISTODOULOU
Annelies Dheedene
Björn Heindryckx
Filip Van Nieuwerburgh
Dieter Deforce
Petra De Sutter
Björn Menten
Etienne Van den Abbeel
A1
Journal Article
in
FERTILITY AND STERILITY
2017
The role of calcium during oocyte maturation, activation and ageing
Yuechao Lu
Petra De Sutter
Björn Heindryckx
Dissertation
2017
Vitrified-thawed mouse oocytes can be efficiently used to determine the oocyte activation potential of human sperm
Davina Bonte
Minerva Ferrer Buitrago
Vanessa Thys
Dieter Deforce
Luc Leybaert
Petra De Sutter
Björn Heindryckx
C3
Conference
2017
Wnt inhibition during hESC culture provides an improved pluripotent state starting point for directed differentiation
Jasin Taelman
Laurentijn Tilleman
Filip Van Nieuwerburgh
Sharat Warrier
Mina Popovic
Margot Van der Jeught
Dieter Deforce
Petra De Sutter
Björn Heindryckx
Susana Marina Chuva de Sousa Lopes
C3
Conference
2017
2016
Assessing the impact of minimizing arginine conversion in fully defined SILAC culture medium in human embryonic stem cells
Ellen Scheerlinck
Katleen Van Steendam
Simon Daled
Elisabeth Govaert
Liesbeth Vossaert
Paulien Meert
Filip Van Nieuwerburgh
Ann Van Soom
Luc Peelman
Petra De Sutter
et al.
A1
Journal Article
in
PROTEOMICS
2016
CRISPR/Cas9-mediated genome editing in naive human embryonic stem cells : an optimized workflow
Eva Jacobs
Sharrat Warrier
Eva D'haene
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conference
2016
Effect of two assisted oocyte activation protocols used to overcome fertilization failure on the activation potential and calcium releasing pattern
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Chloë De Roo
Yuechao Lu
Minerva Ferrer Buitrago
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
FERTILITY AND STERILITY
2016
Elucidating the role of coding and noncoding genes in neuronal development using human embryonic stem cells and the CRISPR/Cas9 system
Eva Jacobs
Sharat Warrier
Eva Van Lombergen
Eva D'haene
Margot Van der Jeught
Björn Heindryckx
Sarah Vergult
Björn Menten
C3
Conference
2016
Establishment and characterization of naïve pluripotency in human embryonic stem cells
Sharat Warrier
Mina Popovic
Margot Van der Jeught
Björn Heindryckx
Bookchapter
in
Stem cell heterogeneity : methods and protocols
2016
Genome egineering through CRISPR/Cas9 technology in the human germline and pluripotent stem cells
Rita Vassena
Björn Heindryckx
R Peco
Guido Pennings
A Raya
A1
Journal Article
in
HUMAN REPRODUCTION UPDATE
2016
Manipulating cell fate in mouse embryos and embryonic stem cells
Sabitri Ghimire
Petra De Sutter
Björn Heindryckx
Dissertation
2016
Massive parallel sequencing uncovers chromosomal mosaicism in human embryonic stem cells in both primed and naive culture conditions
Mina Popovic
Margot Van der Jeught
Franki Speleman
Filip Van Nieuwerburgh
Petra De Sutter
Björn Menten
Björn Heindryckx
C3
Conference
2016
Preimplantation genetic diagnosis (PGD) for translocation carriers using whole genome screening by microarray analysis at the blastocyst stage
CHRISTODOULOS CHRISTODOULOU
Annelies Dheedene
Ilse De Croo
Björn Heindryckx
Lieselot Deleye
Filip Van Nieuwerburgh
Dieter Deforce
Petra De Sutter
Björn Menten
Etienne Van den Abbeel
C3
Conference
2016
Uncovering the novel role of mTORC2 subunit of the PI3K/AKT/mTORC pathway in establishing naive pluripotency in human embryonic stem cells
Sharat Warrier
Margot Van der Jeught
Galbha Duggal
Jasin Taelman
Sylvie Lierman
Susana Marina Chuva de Sousa Lopes
Ann Van Soom
Luc Peelman
Filip Van Nieuwerburgh
Dieter De Coninck
et al.
C3
Conference
2016
Zinc chelation promotes oocyte activation in human oocytes
Davina Bonte
Minerva Ferrer Buitrago
Etienne Van den Abbeel
Margot Van der Jeught
Dieter Deforce
Luc Leybaert
Petra De Sutter
Björn Heindryckx
C3
Conference
2016
2015
Alternative routes to induce naive pluripotency in human embryonic stem cells
Galbha Duggal
Sharat Warrier
Sabitri Ghimire
Dorien Broekaert
Margot Van der Jeught
Sylvie Lierman
Tom Deroo
Luc Peelman
Ann Van Soom
Maria Cornelissen
et al.
A1
Journal Article
in
STEM CELLS
2015
Application of small molecules favoring naive pluripotency during human embryonic stem cell derivation
Margot Van der Jeught
Jasin Taelman
Galbha Duggal
Sabitri Ghimire
Sylvie Lierman
Susana Marina Chuva de Sousa Lopes
Dieter Deforce
Tom Deroo
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
CELLULAR REPROGRAMMING
2015
CRISPR/Cas9-mediated genome editing in primed versus naïve human embryonic stem cells
Eva Jacobs
Sharat Warrier
Eva D'haene
Filip Matthijssens
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conference
2015
Cellular heterogeneity in the level of mtDNA heteroplasmy in mouse embryonic stem cells
Jitesh Neupane
Sabitri Ghimire
Mado Vandewoestyne
Yuechao Lu
Jan Gerris
Rudy Van Coster
Tom Deroo
Dieter Deforce
Stijn Vansteelandt
Petra De Sutter
et al.
A1
Journal Article
in
CELL REPORTS
2015
Comparative analysis of different culture conditions inducing naive pluripotency in human embryonic stem cells
Sharat Warrier
Galbha Duggal
Jasin Taelman
Sylvie Lierman
S Chuva de Sousa Lopes
Ann Van Soom
Luc Peelman
Filip Van Nieuwerburgh
Dieter De Coninck
Björn Menten
et al.
C3
Conference
2015
Cyclin E1 plays a key role in balancing between totipotency and differentiation in human embryonic cells
MV Krivega
M Geens
Björn Heindryckx
S Santos-Ribeiro
H Tournaye
H Van de Velde
A1
Journal Article
in
MOLECULAR HUMAN REPRODUCTION
2015
Derivation conditions affect pluripotency and differentiation propensity of mouse embryonic stem cells
Sabitri Ghimire
Margot Van der Jeught
Jitesh Neupane
Filip Van Nieuwerburgh
Dieter Deforce
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
Björn Heindryckx
C3
Conference
2015
Exogenous supplementation of Activin A enhances germ cell differentiation of human embryonic stem cells
Galbha Duggal
Björn Heindryckx
Sharat Warrier
Jasin Taelman
Margot Van der Jeught
Dieter Deforce
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
A1
Journal Article
in
MOLECULAR HUMAN REPRODUCTION
2015
Human oocyte activation and the causes of fertilization failure
Dimitra Nikiforaki
Petra De Sutter
Björn Heindryckx
Dissertation
2015
Inhibition of transforming growth factor β signaling promotes epiblast formation in mouse embryos
Sabitri Ghimire
Björn Heindryckx
Margot Van der Jeught
Jitesh Neupane
Thomas O'Leary
Sylvie Lierman
Winnok De Vos
Susana Marina Chuva de Sousa Lopes
Tom Deroo
Petra De Sutter
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2015
PLCζ disruption with complete fertilization failure in normozoospermia
Mercè Durban
Montserrat Barragan
Marta Colodron
Minerva Ferrer Buitrago
Petra De Sutter
Björn Heindryckx
Valérie Vernaeve
Rita Vassena
A1
Journal Article
in
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
2015
PLCζ disruption with complete fertilization failure in normozoospermia (vol 32, pg 879, 2015)
Mercè Durban
Montserrat Barragán
Marta Colodron
Minerva Ferrer-Buitrago
Petra De Sutter
Björn Heindryckx
Valérie Vernaeve
Rita Vassena
Correction
2015
Procaine induces cytokinesis in horse oocytes via a pH-dependent mechanism
Bart Leemans
Bart M Gadella
Tom AE Stout
Sonia Heras Garcia
Katrien Smits
Minerva Ferrer Buitrago
Eline Claes
Björn Heindryckx
Winnok De Vos
Hilde Nelis
et al.
A1
Journal Article
in
BIOLOGY OF REPRODUCTION
2015
Procaine induces parthenogenetic cytokinesis in horse oocytes via a pH dependent mechanism
Bart Leemans
Bart M Gadella
Tom AE Stout
Sonia Heras Garcia
Katrien Smits
Minerva Ferrer Buitrago
Eline Claes
Björn Heindryckx
Winnok De Vos
Hilde Nelis
et al.
C3
Conference
2015
Shallow whole genome sequencing is well suited for the detection of chromosomal aberrations in human blastocysts
Lieselot Deleye
Annelies Dheedene
Dieter De Coninck
Tom Sante
CHRISTODOULOS CHRISTODOULOU
Björn Heindryckx
Etienne Van den Abbeel
Petra De Sutter
Dieter Deforce
Björn Menten
et al.
A1
Journal Article
in
FERTILITY AND STERILITY
2015
Stem cells in reproductive medicine: ready for the patient?
R Vassena
C Eguizabal
Björn Heindryckx
K Sermon
C Simon
AMM van Pelt
A Veiga
F Zambelli
A1
Journal Article
in
HUMAN REPRODUCTION
2015
The post-inner cell mass intermediate : implications for stem cell biology and assisted reproductive technology
Margot Van der Jeught
Thomas O'Leary
Galbha Duggal
Petra De Sutter
Susana Marina Chuva de Sousa Lopes
Björn Heindryckx
A1
Journal Article
in
HUMAN REPRODUCTION UPDATE
2015
Whole genome amplification with SurePlex results in better copy number alteration detection using sequencing data compared to the MALBAC method
Lieselot Deleye
Dieter De Coninck
CHRISTODOULOS CHRISTODOULOU
Tom Sante
Annelies Dheedene
Björn Heindryckx
Etienne Van den Abbeel
Petra De Sutter
Björn Menten
Dieter Deforce
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2015
2014
A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model
Jitesh Neupane
Mado Vandewoestyne
Björn Heindryckx
Sabitri Ghimire
Yuechao Lu
Chen Qian
Sylvie Lierman
Rudy Van Coster
Jan Gerris
Tom Deroo
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2014
Assessment of cellular heterogeneity in the level of mitochondrial DNA heteroplasmy in mouse embryonic stem cells
Jitesh Neupane
Björn Heindryckx
Mado Vandewoestyne
Sabitri Ghimire
Yuechao Lu
Rudy Van Coster
Dieter Deforce
Tom Deroo
Petra De Sutter
C3
Conference
2014
Assessment of nuclear transfer techniques to prevent the transmission of heritable mitochondrial disorders without compromising embryonic development competence in mice
Jitesh Neupane
Mado Vandewoestyne
Sabitri Ghimire
Yuechao Lu
Chen Qian
Rudy Van Coster
Jan Gerris
Tom Deroo
Dieter Deforce
Petra De Sutter
et al.
A1
Journal Article
in
MITOCHONDRION
2014
Assisted oocyte activation following ICSI fertilization failure
Frauke Vanden Meerschaut
Dimitra Nikiforaki
Björn Heindryckx
Petra De Sutter
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2014
Detailed method description for noninvasive monitoring of differentiation status of human embryonic stem cells
Ellen Scheerlinck
Katleen Van Steendam
Mado Vandewoestyne
Trees Lepez
Veerle Gobin
Paulien Meert
Liesbeth Vossaert
Filip Van Nieuwerburgh
Ann Van Soom
Luc Peelman
et al.
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
2014
Effect of ionomycin and calcium in the culture medium on the calcium releasing pattern of mouse oocytes and their subsequent embryonic development
Yuechao Lu
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Jitesh Neupane
Chen Qian
Winnok De Vos
JP Ozil
Tom Deroo
Petra De Sutter
Björn Heindryckx
C3
Conference
2014
Identification of histone H3 clipping activity in human embryonic stem cells
Liesbeth Vossaert
Paulien Meert
Ellen Scheerlinck
Pieter Glibert
Nadine Van Roy
Björn Heindryckx
Petra De Sutter
Maarten Dhaenens
Dieter Deforce
A1
Journal Article
in
STEM CELL RESEARCH
2014
Inhibition of TGFß signaling supports embryonic stem cell derivation and the ground state of pluripotency in mouse
Sabitri Ghimire
Björn Heindryckx
Jitesh Neupane
Dieter Deforce
Tom Deroo
Petra De Sutter
C3
Conference
2014
Language development of children born following intracytoplasmic sperm injection (ICSI) combined with assisted oocyte activation (AOA)
Evelien D'haeseleer
Frauke Vanden Meerschaut
Kim Bettens
Anke Luyten
Hannelore Gysels
Ylenia Thienpont
Griet De Witte
Björn Heindryckx
Ann Oostra
Herbert Roeyers
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF LANGUAGE & COMMUNICATION DISORDERS
2014
Mutation-free baby born from a mitochondrial encephalopathy, lactic acidosis and stroke-like syndrome carrier after blastocyst trophectoderm preimplantation genetic diagnosis
Björn Heindryckx
Jitesh Neupane
Mado Vandewoestyne
CHRISTODOULOS CHRISTODOULOU
Yens Jackers
Jan Gerris
Etienne Van den Abbeel
Rudy Van Coster
Dieter Deforce
Petra De Sutter
A1
Journal Article
in
MITOCHONDRION
2014
Neonatal and neurodevelopmental outcome of children aged 3-10 years born following assisted oocyte activation
Frauke Vanden Meerschaut
Evelien D'haeseleer
Hannelore Gysels
Ylenia Thienpont
Grietje Dewitte
Björn Heindryckx
Ann Oostra
Herbert Roeyers
Kristiane Van Lierde
Petra De Sutter
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2014
Oocyte cryopreservation and in vitro culture affect calcium signalling during human fertilization
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Chen Qian
Ilse De Croo
Yuechao Lu
Tom Deroo
Etienne Van den Abbeel
Björn Heindryckx
Petra De Sutter
A1
Journal Article
in
HUMAN REPRODUCTION
2014
Sperm involved in recurrent partial hydatidiform moles cannot induce the normal pattern of calcium oscillations
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Stefanie De Gheselle
Chen Qian
Etienne Van den Abbeel
Winnok De Vos
Tom Deroo
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
FERTILITY AND STERILITY
2014
Toxic effects of Hoechst staining and UV irradiation on preimplantation development of parthenogenetically activated mouse oocytes
Karen Versieren
Björn Heindryckx
Chen Qian
Jan Gerris
Petra De Sutter
A1
Journal Article
in
ZYGOTE
2014
Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation
Margot Van der Jeught
Björn Heindryckx
Thomas O'Leary
Galbha Duggal
Sabitri Ghimire
Sylvie Lierman
Nadine Van Roy
Susana Marina Chuva de Sousa Lopes
Tom Deroo
Dieter Deforce
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2014
Use of pluripotent stem cells for reproductive medicine: are we there yet?
Galbha Duggal
Björn Heindryckx
Tom Deroo
Petra De Sutter
A1
Journal Article
in
VETERINARY QUARTERLY
2014
2013
Analysis of calcium oscillations pattern triggered by human sperm showing failed or low fertilization
Björn Heindryckx
Dimitra Nikiforaki
Leen Caluwaerts
Frauke Vanden Meerschaut
Tom Deroo
Petra De Sutter
C3
Conference
2013
Belgium: ISO 9001:2000 certification as a base for total quality management in ART
Kelly Tilleman
Etienne Van den Abbeel
Ilse De Croo
Anneleen Van De Velde
Björn Heindryckx
Sandra Deltombe
Isabelle Stuyver
Annick Geril
Petra De Sutter
Bookchapter
in
Quality management in ART clinics : a practical guide
2013
Comparison of pre- and post-implantation development following the application of three artificial activating stimuli in a mouse model with round-headed sperm cells deficient for oocyte activation
Frauke Vanden Meerschaut
Dimitra Nikiforaki
Chloë De Roo
Sylvie Lierman
Chen Qian
T Schmitt-John
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
HUMAN REPRODUCTION
2013
De taalontwikkeling van kinderen geboren na kunstmatige bevruchting met geassisteerde eicelactivatie, een pilootstudie
Evelien D'haeseleer
Frauke Vanden Meerschaut
Kim Bettens
Anke Luyten
Hannelore Gysels
Ylenia Thienpont
Griet De Witte
Björn Heindryckx
Ann Oostra
Herbert Roeyers
et al.
A2
Journal Article
in
LOGOPEDIE (HERENTALS)
2013
Derivation of human embryonic stem cells using a post-inner cell mass intermediate
Thomas O'Leary
Björn Heindryckx
Sylvie Lierman
Margot Van der Jeught
Galbha Duggal
Petra De Sutter
Susana M Chuva de Sousa Lopes
A1
Journal Article
in
NATURE PROTOCOLS
2013
Diagnostic and prognostic value of calcium oscillatory pattern analysis for patients with ICSI fertilization failure
Frauke Vanden Meerschaut
Luc Leybaert
Dimitra Nikiforaki
Chen Qian
Björn Heindryckx
Petra De Sutter
A1
Journal Article
in
HUMAN REPRODUCTION
2013
Efficiency and safety of assisted oocyte activation (AOA) in the mouse and the human
Frauke Vanden Meerschaut
Petra De Sutter
Björn Heindryckx
Dissertation
2013
Evaluation of calcium machinery in a meiosis defect mouse model
Yuechao Lu
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Jitesh Neupane
Winnok De Vos
Sylvie Lierman
Tom Deroo
Björn Heindryckx
Petra De Sutter
C3
Conference
2013
Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential
Galbha Duggal
Björn Heindryckx
Sharat Warrier
Thomas O'Leary
Margot Van der Jeught
Sylvie Lierman
Liesbeth Vossaert
Tom Deroo
Dieter Deforce
Susana Marina Chuva de Sousa Lopes
et al.
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2013
Nuclear transfer can prevent mitochondrial DNA carry-over without compromising embryonic development potential in mice
Jitesh Neupane
Mado Vandewoestyne
Björn Heindryckx
Tom Deroo
Yuechao Lu
Sabitri Ghimire
Sylvie Lierman
Chen Qian
Dieter Deforce
Petra De Sutter
C3
Conference
2013
Reference loci for RT-qPCR analysis of differentiating human embryonic stem cells
Liesbeth Vossaert
Thomas O'Leary
Christophe Van Neste
Björn Heindryckx
Jo Vandesompele
Petra De Sutter
Dieter Deforce
A1
Journal Article
in
BMC MOLECULAR BIOLOGY
2013
Regulation of inositol 1,4,5-trisphosphate receptor during human oocyte maturation and fertilization
Dimitra Nikiforaki
Liesbeth Vossaert
Frauke Vanden Meerschaut
Chen Qian
Yuechao Lu
J Parys
Winnok De Vos
Dieter Deforce
Tom Deroo
Etienne Van den Abbeel
et al.
C3
Conference
2013
The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4-and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation
Margot Van der Jeught
Thomas O'Leary
Sabitri Ghimire
Sylvie Lierman
Galbha Duggal
Karen Versieren
Dieter Deforce
Susana Chuva de Sousa Lopes
Björn Heindryckx
Petra De Sutter
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2013
Variance in total levels of phospholipase C zeta (PLC-ζ) in human sperm may limit the applicability of quantitative immunofluorescent analysis as a diagnostic indicator of oocyte activation capability
Junaid Kashir
Celine Jones
Ginny Mounce
Walaa M Ramadan
Bernadette Lemmon
Björn Heindryckx
Petra De Sutter
John Parrington
Karen Turner
Tim Child
et al.
A1
Journal Article
in
FERTILITY AND STERILITY
2013
2012
A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertility
Junaid Kashir
Michalis Konstantinidis
Celine Jones
Bernadette Lemmon
Hoi Chang Lee
Rebecca Hamer
Björn Heindryckx
Charlotte M Deane
Petra De Sutter
Rafael A Fissore
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2012
A sperm's tail: the need to consider temporal aspects of specific physiological mechanisms during and following gamete fusion
J Kashir
Björn Heindryckx
C Jones
Petra De Sutter
J Parrington
Kevin Coward
A1
Journal Article
in
HUMAN REPRODUCTION
2012
Assisted oocyte activation is not beneficial for all patients with a suspected oocyte-related activation deficiency
Frauke Vanden Meerschaut
Dimitra Nikiforaki
Stefanie De Gheselle
Valerie Dullaerts
Etienne Van den Abbeel
Jan Gerris
Björn Heindryckx
Petra De Sutter
A1
Journal Article
in
HUMAN REPRODUCTION
2012
Calcium response during human oocyte activation : the effect of in vitro maturation and cryopreservation
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Chen Qian
Etienne Van den Abbeel
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
Calciumpatroonanalyse tijdens eicelrijping en na toepassing van geassisteerde eicelactivatie
Chloë De Roo
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Yuechao Lu
Sylvie Lierman
Chen Qian
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
Challenges and possible clinical applications of human embryonic stem cell research
Björn Heindryckx
Thomas O'Leary
Margot Van der Jeught
Petra De Sutter
A2
Journal Article
in
PROCEEDINGS OF THE BELGIAN ROYAL ACADEMIES OF MEDICINE
2012
Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells
Junaid Kashir
Michalis Konstantinidis
Celine Jones
Björn Heindryckx
Petra De Sutter
John Parrington
Dagan Wells
Kevin Coward
A1
Journal Article
in
FERTILITY AND STERILITY
2012
Comparison of the effect of ionomycin versus calcimycin on the intracellular calcium level in mouse and human oocytes and subsequent oocyte activation
Frauke Vanden Meerschaut
Chloë De Roo
Dimitra Nikiforaki
Sylvie Lierman
Chen Qian
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
Diagnostic calcium pattern analysis in mouse oocytes for patients with previous fertilization failure following ICSI
Frauke Vanden Meerschaut
Dimitra Nikiforaki
Chen Qian
Björn Heindryckx
Luc Leybaert
Petra De Sutter
C3
Conference
2012
Dose-dependent effect of inhibition of the transforming growth factor beta pathway during early mouse lineage segregation
Sabitri Ghimire
Margot Van der Jeught
Jitesh Neupane
Sylvie Lierman
Thomas O'Leary
Susana Chuva de Sousa Lopes
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
Effect of small molecule supplements during in vitro culture of mouse zygotes and parthenogenetic embryos on hypoblast formation and stem cell derivation
Karen Versieren
Margot Van der Jeught
Thomas O'Leary
Galbha Duggal
Jan Gerris
S Chuva de Sousa Lopes
Björn Heindryckx
Petra De Sutter
A1
Journal Article
in
STEM CELL REVIEWS AND REPORTS
2012
Globozoospermia is mainly due to DPY19L2 deletion via non-allelic homologous recombination involving two recombination hotspots
Elias Ellnati
Paul Kuentz
Claire Redin
Sara Jaber
Frauke Vanden Meerschaut
Joelle Makarian
Isabelle Koscinski
Mohammad H Nasr-Esfahani
Aygul Demirol
Timur Gurgan
et al.
A1
Journal Article
in
HUMAN MOLECULAR GENETICS
2012
Human embryonic stem cell derivation : influences and origin
Thomas O'Leary
Petra De Sutter
Björn Heindryckx
Dissertation
2012
Influence of hESC derivation conditions on germ cell differentiation potential
Galbha Duggal
Björn Heindryckx
Thomas O'Leary
Sylvie Lierman
Dieter Deforce
Susana Chuva de Sousa Lopes
Petra De Sutter
C3
Conference
2012
Influence of human sperm motility and cryopreservation on the oocyte activating factor phospholipase C zeta
Björn Heindryckx
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Winnok De Vos
Sylvie Lierman
Petra De Sutter
C3
Conference
2012
Morphological survival of twice-cryopreserved human embryos
Sylvie Lierman
Ilse De Croo
Björn Heindryckx
Etienne Van den Abbeel
Petra De Sutter
C3
Conference
2012
Poor correlation between polar bodies and blastomere mutation load in a patient with m.3243A>G tRNALeu(UUR) point mutation
Mado Vandewoestyne
Björn Heindryckx
Stefanie De Gheselle
Trees Lepez
Jitesh Neupane
Jan Gerris
Rudy Van Coster
Petra De Sutter
Dieter Deforce
A1
Journal Article
in
MITOCHONDRION
2012
Pronuclear transfer in mice yields minimal mitochondrial DNA carry-over
Mado Vandewoestyne
Jitesh Neupane
Björn Heindryckx
Sylvie Lierman
Dieter Deforce
Petra De Sutter
C3
Conference
2012
Reliability of pre-implantation genetic diagnosis in a heteroplasmic mitochondrial mouse model
Jitesh Neupane
Mado Vandewoestyne
Björn Heindryckx
Sabitri Ghimire
Yuechao Lu
Chen Qian
Dieter Deforce
Petra De Sutter
C3
Conference
2012
Reliability of pre-implantation genetic diagnosis in a heteroplasmic mitochondrial mouse model
Jitesh Neupane
Mado Vandewoestyne
Björn Heindryckx
Sabitri Ghimire
Yuechao Lu
Sylvie Lierman
Chen Qian
Dieter Deforce
Petra De Sutter
C3
Conference
2012
The TGFβ pathway plays a pivotal role in early embryo lineage segregation
Margot Van der Jeught
Sabitri Ghimire
Thomas O'Leary
Sylvie Lierman
Dieter Deforce
Susana Chuva de Sousa Lopes
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
The effect of oocyte aging on the calcium oscillations and embryo development of in vivo and in vitro matured oocytes
Yuechao Lu
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Jitesh Neupane
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
The influence of patient and cohort parameters on the incidence and developmental potential of embryos with poor quality traits for use in human embryonic stem cell derivation
Thomas O'Leary
Galbha Duggal
Sylvie Lierman
Etienne Van den Abbeel
Björn Heindryckx
Petra De Sutter
A1
Journal Article
in
HUMAN REPRODUCTION
2012
Tracking the progression of X-chromosome inactivation and reactivation during female human embryonic stem cell derivation
Thomas O'Leary
Björn Heindryckx
Margot Van der Jeught
Galbha Duggal
Susana Chuva de Sousa Lopes
Petra De Sutter
C3
Conference
2012
Tracking the progression of the human inner cell mass during embryonic stem cell derivation
Thomas O'Leary
Björn Heindryckx
Sylvie Lierman
David van Bruggen
Jelle J Goeman
Mado Vandewoestyne
Dieter Deforce
Susana M Chuva de Sousa Lopes
Petra De Sutter
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2012
Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation
Margot Van der Jeught
Thomas O'Leary
Sylvie Lierman
Dieter Deforce
Susana Chuva de Sousa Lopes
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
2011
Aberrant spindle structures responsible for recurrent human metaphase I oocyte arrest with attempts to induce meiosis artificially
Björn Heindryckx
Sylvie Lierman
CM Combelles
Claude Cuvelier
Jan Gerris
Petra De Sutter
A1
Journal Article
in
HUMAN REPRODUCTION
2011
Calcium releasing ability of human sperm with deficient oocyte activation capacity
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Chen Qian
Dieter Deforce
Esther Van den Abbeel
K Coward
J Parrington
Luc Leybaert
Björn Heindryckx
Petra De Sutter
C3
Conference
2011
Culture optimisation to direct differentiation of human embryonic stem cells into primordial germ cells
Galbha Duggal
Björn Heindryckx
Thomas O'Leary
Sylvie Lierman
Dieter Deforce
S Chuva de Sousa Lopes
Petra De Sutter
C3
Conference
2011
Differential apoptotic staining of mammalian blastocysts based on double immunofluorescent CDX2 and active caspase-3 staining
Eline Wydooghe
Leen Vandaele
Josine Beek
Herman Favoreel
Björn Heindryckx
Petra De Sutter
Ann Van Soom
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
2011
Efficiency of polarized microscopy as a predictive tool for human oocyte quality
Björn Heindryckx
Stefanie De Gheselle
Sylvie Lierman
Jan Gerris
Petra De Sutter
A1
Journal Article
in
HUMAN REPRODUCTION
2011
Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes
Junaid Kashir
Celine Jones
Hoi Chang Lee
Katja Rietdorf
Dimitra Nikiforaki
Claire Durrans
Margarida Ruas
Sze Tian Tee
Björn Heindryckx
Antony Galione
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2011
Phospholipase Cβ1 as a possible oocyte factor responsible for successful oocyte activation and embryo development
Frauke Vanden Meerschaut
Björn Heindryckx
Chen Qian
Dieter Deforce
Luc Leybaert
Petra De Sutter
C3
Conference
2011
Polar body mutation load analysis in a patient with A3243G tRNALeu(UUR) point mutation
Mado Vandewoestyne
Björn Heindryckx
Trees Lepez
Rudy Van Coster
Jan Gerris
Petra De Sutter
Dieter Deforce
A1
Journal Article
in
MITOCHONDRION
2011
Slow controlled-rate freezing of human in vitro matured oocytes: effects on maturation rate and kinetics and parthenogenetic activation
Karen Versieren
Björn Heindryckx
Thomas O'Leary
Ilse De Croo
Etienne Van den Abeel
Jan Gerris
Petra De Sutter
A1
Journal Article
in
FERTILITY AND STERILITY
2011
Slow controlled-rate freezing of human in vitro matured oocytes: effects on maturation rate and kinetics, parthenogenesis and spindle structure
Karen Versieren
Björn Heindryckx
Ilse De Croo
Sylvie Lierman
Winnok De Vos
Esther Van den Abbeel
Jan Gerris
Petra De Sutter
C3
Conference
2011
The influence of early embryo traits on human embryonic stem cell derivation efficiency
Thomas O'Leary
Björn Heindryckx
Sylvie Lierman
Margot Van der Jeught
Björn Menten
Dieter Deforce
Maria Cornelissen
Susana Chuva de Sousa Lopes
Petra De Sutter
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2011
2010
Comparison of three artificial activating stimuli using a mouse model deficient for oocyte activation
Björn Heindryckx
Frauke Vanden Meerschaut
Sylvie Lierman
Chen Qian
Thomas O'Leary
Jan Gerris
Petra De Sutter
C3
Conference
2010
Developmental competence of parthenogenetic mouse and human embryos after chemical or electrical activation
Karen Versieren
Björn Heindryckx
Sylvie Lierman
Jan Gerris
Petra De Sutter
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2010
Efficiency of assisted oocyte activation (AOA) in patients with an oocyte factor deficiency diagnosed by the mouse oocyte activation test (MOAT)
Frauke Vanden Meerschaut
Björn Heindryckx
Stefanie De Gheselle
Valerie Dullaerts
Jan Gerris
Petra De Sutter
C3
Conference
2010
Identification and functional characterization of a point mutation in the gene encoding the sperm factor phospholipase C zeta in an infertile male
J Kashir
C Jones
C Young
M Ruas
P Grasa
K Rietdorf
Elke Heytens
Björn Heindryckx
SY Yoon
RA Fissore
et al.
C3
Conference
2010
Oocyte activation, phospholipase C zeta and human infertility
J Kashir
Björn Heindryckx
C Jones
Petra De Sutter
J Parrington
K Coward
A1
Journal Article
in
HUMAN REPRODUCTION UPDATE
2010
Techniques to prevent mitochondrial mutation transmission
Björn Heindryckx
Mado Vandewoestyne
Dieter Deforce
Petra De Sutter
C3
Conference
2010
Toxic effects of Hoechst staining and UV-irradiation on preimplantation development of parthenogenetically activated mouse oocytes
Karen Versieren
Björn Heindryckx
Chen Qian
Jan Gerris
Petra De Sutter
C3
Conference
2010
2009
Behandeling van gefaalde bevruchting na ICSI
Björn Heindryckx
Petra De Sutter
A4
Journal Article
in
Freya
2009
Somatic Nuclear Transfer to In Vitro-Matured Human Germinal Vesicle Oocytes
Björn Heindryckx
Petra De Sutter
Jan Gerris
Bookchapter
in
Stem Cells in Human Reproduction - Basic Science and Therapeutic Potential
2009
2008
Efficiency of assisted oocyte activation as a solution for failed intracytoplasmic sperm injection
Björn Heindryckx
Stefanie De Gheselle
Jan Gerris
Marc Dhont
Petra De Sutter
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2008
Optimization of Somatic Cell Nuclear Transfer (SCNT).
Björn Heindryckx
Jan Gerris
Marc Dhont
Petra De Sutter
C1
Conference
2008
Polscope imaging in the IVF&research lab
Björn Heindryckx
C1
Conference
2008
2007
Embryo development after successful somatic cell nuclear transfer to in vitro matured human germinal vesicle oocytes
Björn Heindryckx
Petra De Sutter
Jan Gerris
Marc Dhont
Josiane Van der Elst
A1
Journal Article
in
HUMAN REPRODUCTION
2007
High success rate of assisted oocyte activation after a diagnostic mouse oocyte activation test in couples with low or failed fertilization after ICSI
Björn Heindryckx
Stefanie De Gheselle
Leen Vanhoutte
Jan Gerris
Marc Dhont
Petra De Sutter
C3
Conference
2007
Kunstmatige geslachtscellen en geassisteerde eicelactivatie. Een experimentele bijdrage tot onvruchtbaarheidsonderzoek en -behandeling
Björn Heindryckx
Josiane Van der Elst
Petra De Sutter
Marc Dhont
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2007
Kunstmatige geslachtscellen en geassisteerde eicelactivatie. Een experimentele bijdrage tot onvruchtbaarheidsonderzoek en –behandeling.
Björn Heindryckx
Josiane Van der Elst
Petra De Sutter
Marc Dhont
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2007
2006
Assisted oocyte activation during ICSI
Björn Heindryckx
Petra De Sutter
Marc Dhont
Jan Gerris
A2
Journal Article
in
Embryo Talk
2006
Back muscle transplantation model for ovarian allo- and xenografts
Reza Soleimani
J LIU
Björn Heindryckx
Rudy Van den Broecke
Petra De Sutter
Jan Gerris
Marc Dhont
Josiane Van der Elst
C3
Conference
2006
Culture medium preferences of pre-implantation cloned mouse embryos
Björn Heindryckx
Josiane Van der Elst
Marc Dhont
Bookchapter
in
Nuclear transfer protocols : cell reprogramming and transgenesis
2006
Experimental contribution to infertility research : artificial gametes and assisted oocyte activation
Björn Heindryckx
Marc Dhont
Josiane Van der Elst
Dissertation
2006
In vitro matured oocytes for human cloning
Björn Heindryckx
C1
Conference
2006
Optimisation of Somatic Cell Nuclear Transfer as a Strategy for Infertility Treatment
Björn Heindryckx
Petra De Sutter
Marc Dhont
Jan Gerris
A4
Journal Article
in
Embryo Talk
2006
Optimisation of Somatic Cell Nuclear Transfer in Mice as a strategy for Infertility Treatment
Björn Heindryckx
Petra De Sutter
Marc Dhont
Jan Gerris
A2
Journal Article
in
Embryo Talk
2006
2005
Treatment option for sperm- or oocyte-related fertilization failure: assisted oocyte activation following diagnostic heterologous ICSI
Björn Heindryckx
Josiane Van der Elst
Petra De Sutter
Marc Dhont
A1
Journal Article
in
HUMAN REPRODUCTION
2005
2004
Chromosome number and development of artificial mouse oocytes and zygotes
Björn Heindryckx
Sylvie Lierman
Josiane Van der Elst
Marc Dhont
A1
Journal Article
in
HUMAN REPRODUCTION
2004
Human Pregnancies after assisted oocyte activation during ICSI in sperm- and oocyte-borne activation failure
Björn Heindryckx
Josiane Van der Elst
Petra De Sutter
Marc Dhont
C1
Conference
2004
2003
De muizenoöcytactivatietest en geassisteerde eicelactivatie bij ICSI
Björn Heindryckx
Sylvie Lierman
Petra De Sutter
Josiane Van der Elst
Marc Dhont
A2
Journal Article
in
TIJDSCHRIFT VOOR FERTILITEITSONDERZOEK
2003
2002
Developmental potential of cloned mouse embryos reconstructed by a conventional technique of nuclear injection.
Andrei Rybouchkin
Björn Heindryckx
Josiane Van der Elst
Marc Dhont
A1
Journal Article
in
REPRODUCTION
2002
Serial pronuclear transfer increases the developmental potential of in vitro-matured oocytes in mouse cloning.
Björn Heindryckx
Andrei Rybouchkin
Josiane Van der Elst
Marc Dhont
A1
Journal Article
in
BIOLOGY OF REPRODUCTION
2002
2001
Effect of culture media on in vitro development of cloned mouse embryos
Björn Heindryckx
Andrei Rybouchkin
Josiane Van der Elst
Marc Dhont
A2
Journal Article
in
CLONING
2001