Contribution of immune cells to vascular wall damage and dissection in Marfan syndrome

Advanced Imaging and Biomechanical Modeling for Cardiovascular Phenotyping in Adult Zebrafish

Biomechanics-based phenotyping of the cardiovascular system in small animal models of heritable connective tissue disease

Dissecting the molecular basis of arterial tortuosity

Doctoral project Regina Le Roux

Doctoral project Silke De Feyter

Exploration of avenues for Precision Medicine in Heritable Thoracic Aortic Diseases

From Mice to Humans: Elucidating Cardiovascular Complications of Marfan Syndrome

Impact of protein-bound uremic toxin- driven inflammation on growth in pediatric chronic kidney disease

Investigating Aortic Pathology and Optimizing Precision Gene Editing in Zebrafish: Roles of SMAD3, SMAD6, and GLUT10

Unraveling the pathophysiology of myocardial disease in Marfan syndrome

Using a zebrafish model to improve diagnosis, risk estimation and treatment of cardiovascular manifestations of Marfan syndrome.

A versatile microscope for the imaging of living and fixed biological samples

Belgian Heart Fund: "Exploring the cell-specific mechanisms of aortic disease using fibrillin-1 mutant mouse models"

Investigating the mechanisms of aortic disease using zebrafish and mouse models

A zebrafish platform for genetic and chemical screening to improve diagnosis, risk estimation and treatment of cardiovascular manifestations in Marfan syndrome.

Contribution of immune cells to vascular wall damage and dissection in Marfan syndrome

Evaluating impaired neural crest fate in a zebrafish model for aortic dissection as a therapeutic target for thoracic aortic dissection

Strategic Institutional Partnership Brigham and Women's Hospital and Harvard Medical School

ThirdGenT: linking third-generation sequencing of (epi)genomes, (epi)transcriptomes and translatomes to life sciences revolutionizes oncology, rare diseases, microbiology, cell and gene technology, developmental and computational biology

Upgrade of confocal FLIM microscope with two-photon excitation and detection modules

White light laser-based confocal fluorescence lifetime imaging microscope for multi-parameter 3D live imaging

Using Zebrafish as a novel tool to Improve the Diagnosis and Outcome of Marfan Syndrome

Comprehensive understanding of Uremic toxin driven clinical and molecular mechanisms of PEDIatric CKD-induced VASculopathy - an impulse project to identify novel diagnostic and therapeutic targets

Growth failure in pediatric CKD: a search for new therapeutic targets to mitigate inflammation driven by protein-bound uremic toxins accumulation