Tracking epigenetic plasticity in circulating tumor-derived DNA to monitor drug resistance and guide personalized treatment in cancer patients

A SIOPEN pragmatic clinical trial to MOnitor NeuroblastomA relapse with LIquid biopsy Sensitive Analysis

Bioinformatics for future precision medicine in cancer treatment

Development of a data-mining pipeline for drug target identification from circulating transcriptomes of lung cancer patients

Development of a fast, minimally-invasive and affordable test for accurate diagnosis of Cancer of Unknown Primary (CUP) using DNA methylation profiling.

Development of a minimally-invasive test for accurate diagnosis of Cancer of Unknown Primary (CUP) using DNA methylation profiling

Development of a non-invasive test to predict immunotherapy response in lung cancer patients

Development of a toolbox for temporal monitoring of pediatric cancers using liquid biopsy samples

NIPITplus, a multi-cancer blood test to predict immune checkpoint inhibitor response and monitor toxicity

Non invasive drug identification for tumors (NIDIT): a tool for precision oncology

Non-invasive prediction of immune-therapy response in lung cancer patients (NIPIT)

Non-invasive prediction of immunotherapy response for lung cancer patients

Prediction of immunotherapy response and toxicity in melanoma, renal cell and lung cancer using transcriptome based systemic immune phenotyping.

Single cell expression profiling of neuroblastoma in search of novel treatment approaches for chemoresistant clones

SOX11 controlled SWI/SNF combinatorial assembly and neuroblastoma super-enhancer landscaping

Special Research Fund Professorship in Translational genomics and bioinformatics

The neuroblastoma 17q enigma: exploiting zebrafish modeling to study the cooperative role of 17q genes in MYCN driven tumor formation

The SOX11 transcription factor as “lineage survival” oncogene in neuroblastoma

Universal, cost-effective and hypersensitive open-source technology platform for liquid biopsy based on methylome profiling of circulating DNA.

Unraveling neuroblastoma subtype 2A using differential network methods.

Functional study of the ALK-F1174 mutation in

Gene-Environment iNteractions in the pathogenesis of Tobacco smoking-induced Lung diseases (GENT-Lung)

Reconstruction of dynamic initiation and progression gene expression regulatory networks in neuroblastoma

SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomics

The DNA methylome in Common Variable Immunodeficiencies (CVID): a comprehensive study characterizing its heterogeneity and its role in disease subclassification

Reconstructing m(i)RNA regulatory networks implicated in invasion and metastasis in neuroblastoma

Special Research Fund Professorship in Translational genomics and bioinformatics

Study of neuroblastoma oncogenesis through mRNA and miRNA expression profiling of normal neuroblasts and neuroblastoma stem cells

Replication fork protector dependency factors: novel targets for combination treatment and immunomodulation in neuroblastoma (REINFORCE)