Clinical translation of vaccine strategies in combination with immune checkpoint inhibtion in non-small cell lung cancer

Reprogramming tumor-homing myeloid cells as a cell therapy for immune-refractory cancers

Doctoral project Alvaro Marcos Rubio

Doctoral project Reinhart Speeckaert

Neoantigen identification on diagnostic biopsies from patients with lung cancer

Neoepitope identification for cancer immunotherapy

Blocking unwanted macrophage phagocytosis by triggering sialoadhesin to enhance tumor derived apopto

Development of gene-modified cellular immunotherapies against immunological "cold" cancers

Diagnostic examinations of an autologous tumor-immune xenograft as a test platform for immunotherapeutic intervention with non-small cell lung cancer

Gene-Environment iNteractions in the pathogenesis of Tobacco smoking-induced Lung diseases (GENT-Lung)

HIGH-THROUGHPUT, HIGH-SENSITIVITY AND COST-EFFECTIVE MONITORING OF INNATE AND ADAPTIVE IMMUNE RESPONSES AT SINGLE CELL LEVEL

Immunopeptidomics-based Development of Next-Generation Bacterial mRNA Vaccines

Improving outcome of immune checkpoint blockade in lung cancer by combination with a tumor mutanome-targeted dendritic cell vaccine

IP strenghtening for MIDRIX, a unique manufacturing process for dendritic cell immunotherapy in solid cancers

MesoBreath 3: Analysis of Volatile Organic Compounds from mesothelioma cells and pleural effusions with gas chromatography-mass spectrometry (GC_MS) and ion mobility spectrometry (IMS)

Oxygen-sensing by professional antigen presenting cells in the tumor micro-environment and its impact on adaptive anti-tumor immunity.

Proteomics-derived epitopes for dramatically improved anticancer and antibacterial vaccine development

REACTION: A modular mRNA-encoded artificial receptor for focused re-ignition of anti-cancer immune responses

REACTION: A modular mRNA-encoded artificial receptor for focused re-ignition of anti-cancer immune responses

Reprogramming of tumor-associated dendritic cells on microRNA level as a novel immune escape mechanism in cancer

SparXells™ : Enabling Next-Generation Dendritic Cell Therapy in Lung cancer and Beyond

TARgeted Mrna re-engineering for enhanced Antibody and Cellular immunity (TARMAC)

Use of an integrative classification system and next-generation sequencing strategies for gene identification in common variable immunodeficiency disorder (CVID)

An autologous tumor-immune system humanized mouse model for the development of dendritic cell-based vaccines in lung cancer

A patient derived xenograft (PDX) platform for in vivo evaluation of novel anticancer therapies

Automatic bench-top cell sorter with biosafety hood for use in a level 3 class biosafety laboratory

BioGelator for local immunotherapy

Development of a non-invasive test to predict immunotherapy response in lung cancer patients

Engineered microparticulate cancer vaccines based on tumour-specific antigens formulated with immune-modulating polymers

FullPicture: Combining Spectral Flow Cytometry with High-Speed Cell Imaging to enable comprehensive profiling of plant and animal cells and their components in real time.

Gene-Environment iNteractions in the pathogenesis of Tobacco smoking-induced Lung diseases (GENT-Lung)

Immunomonitoring of patients with non-small cell lung carcinoma treated with a tumor mutanome-targeted dendritic cell vaccine

Improving outcome of immune checkpoint blockade in lung cancer by combination with a tumor mutanome-targeted dendritic cell vaccine

Improving outcome of immune checkpoint blockade in lung cancer by combination with a tumor mutanome-targeted dendritic cell vaccine

Longitudinal imaging of cellular dynamics with a biostation IM-Q (microscope with sensitive CCD camera and integrated incubator)

Non-invasive drug identification for tumors: a tool for precision oncology

Non-invasive prediction of immune-therapy response in lung cancer patients (NIPIT)

Research Equipment: BD LSRFortessa TM flowcytometer

Use of an integrative classification system and next-generation sequencing strategies for gene identification in common variable immunodeficiency disorder (CVID).

An integrated strategy for preclinical development of improved vaccines against dendritrische cell lung cancer