Research Explorer

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Researcher

Karim Vermaelen

Publications & Research Data

Awards & Distinctions

103 Results

2025

Chitosan/γ-PGA nanoparticles and IFN-γ immunotherapy : a dual approach for triple-negative breast cancer treatment

Flávia Raquel Teixeira De CastroMarta Laranjeiro PintoCatarina Leite PereiraKarine SerreÂngela Margarida CostaBruno CavadasMário Adolfo BarbosaKarim VermaelenSergio LeónDiego Serrano et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Immune checkpoint-induced colitis : a single-center retrospective cohort study

Bengt Van HolderJulie VereeckeNathan UreelTriana Lobatón OrtegaAnne HoorensAmber LievensMarie TruyensSylvie RotteyKarim VermaelenVenita D'Cruz et al.

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Outcome of temozolomide in relapsed small cell lung cancer: A retrospective single center analysis

Sofie DhaeyerElise MissaultVeerle SurmontKarim VermaelenDieter Stevens

U Journal Article in Lung Cancer

Systemic immune epigenomic predictors of immunotherapy response in NSCLC patients : potential and pitfalls

Alvaro Marcos RubioKatleen De PreterCeline EveraertKarim Vermaelen

2024

A co-culture model to study modulators of tumor immune evasion through scalable arrayed CRISPR-interference screens

Ramiro MartinezChiara FinocchiaroLouis DelhayeFien GysensJasper AnckaertWim TrypsteenMaarten VerstevenEva LionSandra Van LintKarim Vermaelen et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Defining the optimal setting for transcriptomic analyses on blood samples for response prediction in immunotherapy-treated NSCLC patients

Alvaro Marcos RubioSeoyeon OhSofie RoelandtDieter StevensEufra Van DammeKarim VermaelenKatleen De PreterCeline Everaert

A1 Journal Article in SCIENTIFIC REPORTS

Development and clinical evaluation of a dendritic cell vaccine targeting patient-individual neoantigens in lung cancer

Joline IngelsBart VandekerckhoveKarim Vermaelen

Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Joline IngelsLaurenz De CockDieter StevensRupert MayerFabien Henri TheryGuillem Sanchez SanchezDavid VermijlenKarin WeeningSaskia De SmetNele Lootens et al.

A1 Journal Article in CELL REPORTS MEDICINE

2023

Circulating immune cell dynamics as outcome predictors for immunotherapy in non-small cell lung cancer

Alvaro Marcos RubioCeline EveraertEufra Van DammeKatleen De PreterKarim Vermaelen

A1 Journal Article in JOURNAL FOR IMMUNOTHERAPY OF CANCER

Deconvolution-based estimation of immune cell fractions in blood for immunotherapy response prediction in non-small cell lung cancer patients

Alvaro Marcos RubioCeline EveraertSofie RoelandtEufra Van DammeDieter StevensKarim VermaelenKatleen De Preter

MIDRIXNEO-LUNG : safety and immunogenicity of a neoantigen-presenting autologous dendritic cell therapy in resected NSCLC patients

Joline IngelsLaurenz De CockDieter StevensKarin WeeningVeerle SurmontJo Van DorpeFrancis ImpensBjörn MentenKarim VermaelenBart Vandekerckhove

2022

Application of an ultrasensitive NGS-based blood test for the diagnosis of early-stage lung cancer : sensitivity, a hurdle still difficult to overcome

Malaïka Van der LindenBram Van GaeverLennart RamanKarim VermaelenIngel DemedtsVeerle SurmontUlrike HimpeYolande LievensLiesbeth FerdinandeFranceska Dedeurwaerdere et al.

A1 Journal Article in CANCERS

Cell type deconvolution as a strategy to develop a blood-based test for immunotherapy response prediction in lung cancer patients

Alvaro Marcos RubioCeline EveraertEufra Van DammeDieter StevensSofie RoelandtKarim VermaelenKatleen De Preter

Headspace volatile organic compound profiling of pleural mesothelioma and lung cancer cell lines as translational bridge for breath research

Eline JanssensZoë MolLore VandermeerschSabrina LagniauKarim VermaelenJan Van MeerbeeckChristophe WalgraeveElly MarcqKevin Lamote

A1 Journal Article in FRONTIERS IN ONCOLOGY

Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials

Joline IngelsLaurenz De CockRupert MayerPam DevrekerKarin WeeningKelly HeynsNele LootensSaskia De SmetMarieke BrusseelStijn De Munter et al.

A1 Journal Article in CYTOTHERAPY

2021

Afatinib for the treatment of advanced non-small-cell lung cancer harboring an epidermal growth factor receptor exon 18 E709_T710delinsD mutation : a case report

Lander Van AckerDieter StevensKarim VermaelenVeerle Surmont

A2 Journal Article in JOURNAL OF MEDICAL CASE REPORTS

Dendritic cell-based immunotherapy in lung cancer

Dieter StevensJoline IngelsSandra Van LintBart VandekerckhoveKarim Vermaelen

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Diagnosing COVID-19 : towards a feasible COVID-19 rule-out protocol

Jozefien De ClercqThomas MalfaitSimon MalfaitJerina BoelensLiselotte CoorevitsElizaveta PadalkoStien VandendriesscheBruno VerhasseltLieve MorbéeFre Bauters et al.

A1 Journal Article in ACTA CLINICA BELGICA

Managing viral hepatitis in cancer patients under immune checkpoint inhibitors : should we take the risk?

Stijn De KeukeleireTijl VermassenZahra Mosala NezhadTessa KerreVibeke KruseHans Van VlierbergheKarim VermaelenSylvie Rottey

A1 Journal Article in IMMUNOTHERAPY

mRNA in cancer immunotherapy : beyond a source of antigen

Lien Van HoeckeRein VerbekeHeleen DewitteIne LentackerKarim VermaelenKarine BreckpotSandra Van Lint

A1 Journal Article in MOLECULAR CANCER

The RNA Atlas expands the catalog of human non-coding RNAs

Lucia LorenziHua-Sheng ChiuFrancisco Avila CobosStephen GrossPieter-Jan VoldersRobrecht CannoodtJustine NuytensKatrien VanderheydenJasper AnckaertSteve Lefever et al.

A1 Journal Article in NATURE BIOTECHNOLOGY

The RNA Atlas expands the catalog of human non-coding RNAs (June, 10.1038/s41587-021-00936-1, 2021)

Lucia LorenziHua-Sheng ChiuFrancisco Avila CobosStephen GrossPieter-Jan VoldersRobrecht CannoodtJustine NuytensKatrien VanderheydenJasper AnckaertSteve Lefever et al.

Treatment of a patient with severe cytomegalovirus (CMV) infection after haploidentical stem cell transplantation with donor-derived CMV-specific T cells

Joline IngelsSaskia De SmetKelly HeynsNele LootensJonas SegaertTom TaghonGeorges LeclercqKarim VermaelenEvelyne WillemsEtienne Baudoux et al.

A1 Journal Article in ACTA CLINICA BELGICA

2020

Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever

Hanne Van GorpLinyan HuangPedro Henrique Viana SaavedraMarnik VuylstekeTomoko AsaokaGiusi PrencipeAntonella InsalacoBenson OgunjimiJerold JeyaratnamIlaria Cataldo et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Chitosan/γ-PGA nanoparticles-based immunotherapy as adjuvant to radiotherapy in breast cancer

Flávia CastroMarta L. PintoCatarina L. PereiraKarine SerreMário A. BarbosaKarim VermaelenFátima GärtnerRaquel M. GonçalvesOlivier De WeverMaria J. Oliveira

A1 Journal Article in BIOMATERIALS

Shallow whole-genome sequencing of plasma cell-free DNA accurately differentiates small from non-small cell lung carcinoma

Lennart RamanMalaïka Van der LindenKim Van der EeckenKarim VermaelenIngel DemedtsVeerle SurmontUlrike HimpeFranceska DedeurwaerdereLiesbeth FerdinandeYolande Lievens et al.

A1 Journal Article in GENOME MEDICINE

Tackling diagnostic challenges during the first wave of COVID-19

Jozefien De ClercqThomas MalfaitSimon MalfaitLiselotte CoorevitsElizaveta PadalkoStien VandendriesscheBruno VerhasseltLieve MorbéeFre BautersKatrien Hertegonne et al.

To treat or not to treat? Managing comorbidities in cancer patients under immune checkpoint inhibition

Stijn De KeukeleireTijl VermassenGert De SchoenmakereVibeke KruseKarim VermaelenSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

2019

The RNA Atlas, a single nucleotide resolution map of the human transcriptome

Lucia LorenziHua-Sheng ChiuFrancisco Avila CobosStephen GrossPieter-Jan VoldersRobrecht CannoodtJustine NuytensKatrien VanderheydenJasper AnckaertSteve Lefever et al.

Vaccine strategies to improve anti-cancer cellular immune responses

Karim Vermaelen

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2018

An accelerated, clinical-grade protocol to generate high yields of type 1-polarizing messenger RNA loaded dendritic cells for cancer vaccination

Elisabeth BrabantsKelly HeynsS De SmetPam DevrekerJoline IngelsNancy De CabooterVeronique DebackerMelissa DullaersJP Van MeerbeeckBart Vandekerckhove et al.

A1 Journal Article in CYTOTHERAPY

An unusual presentation of a case of human psittacosis

Yannick Vande WeygaerdeCharlot VersteeleElke ThijsAnton De SpiegeleerJerina BoelensDaisy VanrompayEva Van BraeckelKarim Vermaelen

A2 Journal Article in RESPIRATORY MEDICINE CASE REPORTS

Immunoengineering through cancer vaccines - A personalized and multi-step vaccine approach towards precise cancer immunity

Lien LybaertKarim VermaelenBruno De GeestLutz Nuhn

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Invasive aspergillosis mimicking metastatic lung cancer

Michiel VanfleterenAnne-Marie C DingemansVeerle SurmontKarim VermaelenAlida A PostmaAstrid ML Oude lashofCordula CM PitzLizza EL Hendriks

A1 Journal Article in FRONTIERS IN ONCOLOGY

Monocyte-derived dendritic cells in lung cancer : from partner in crime to therapeutic option

Elisabeth BrabantsKarim VermaelenJan Van Meerbeeck

Perspectives on the integration of immuno-oncology biomarkers and drugs in a health care setting

Karim VermaelenA WaeytensO KholmanskikhM Van den BulckeE Van Valckenborgh

A1 Journal Article in SEMINARS IN CANCER BIOLOGY

2017

Bijwerkingen van 'immune checkpoint' inhibitoren : waar dient een huisarts alert op te zijn?

S De KeukeleireTessa KerrePiet OstBarbara De MoerlooseKarim VermaelenLieve BrochezVibeke Kruse

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Biomarkers for early diagnosis of malignant mesothelioma : do we need another moonshot?

Sabrina LagniauKevin LamoteJan Van MeerbeeckKarim Vermaelen

A1 Journal Article in ONCOTARGET

Combined high dose radiation and pazopanib in metastatic renal cell carcinoma : a phase I dose escalation trial

Katrien De WolfSylvie RotteyKarim VermaelenKarel DecaesteckerNora SundahlLizzy De LobelEls GoetghebeurGert De MeerleerNicolaas LumenValerie Fonteyne et al.

A1 Journal Article in RADIATION ONCOLOGY

Polyelectrolyte-enrobed cancer cells in view of personalized immune-therapy

Lien LybaertKeun Ah RyuRiet De RyckeAlfred C ChonOlivier De WeverKarim VermaelenAaron Esser-KahnBruno De Geest

A1 Journal Article in ADVANCED SCIENCE

The immunophenotypic fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Delfien BogaertMarieke De BruyneVeronique DebackerPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéMaria Bordon Cueto De BraemBart LambrechtTessa Kerre et al.

A1 Journal Article in HAEMATOLOGICA

The immunophenotypical fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Delfien BogaertMarieke De BruyneVeronique DebackerPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéMaria Bordon Cueto De BraemBart LambrechtTessa Kerre et al.

The ION-Ghent guidelines for the management of immune related adverse events (irAE's)

Vibeke KruseMax SchreuerKarim VermaelenPiet OstTessa KerreBarbara De MoerlooseLieve Brochez

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

The role of dicer in alveolar macrophages and dendritic cells in smoke-induced inflammation

Elise De SmetPieter MestdaghS ProvoostLeen SeysGuy JoosKarim VermaelenGuy BrusselleKen Bracke

The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome

Lotte PyfferoenElisabeth BrabantsCeline EveraertNancy De CabooterKelly HeynsKim DeswarteManon VanheerswynghelsSofie De PrijckGlenn WaegemansMelissa Dullaers et al.

A1 Journal Article in ONCOIMMUNOLOGY

2016

CVID, isolated IgG deficiency and isolated IgG subclass deficiency : clinical features and B cell maturation of the Ghent cohort

Delfien BogaertVeronique De BackerTessa KerreMaria Bordon Cueto De BraemBart LambrechtKarim VermaelenFrans De BaetsElfride De BaereMelissa DullaersFilomeen Haerynck

Development of a blood test for selection of lung cancer patients who could benefit from immunotherapy.

Malaïka Van der LindenKarim VermaelenIngel DemedtsVeerle SurmontKathleen ClaesBjörn MentenJo Van Dorpe

Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation

Hanne Van GorpPedro Henrique Viana SaavedraNathalia Moraes de VasconcelosNina Van OpdenboschLieselotte Vande WalleMagdalena MatusiakGiusi PrencipeAntonella InsalacoFilip Van HauwermeirenDieter Demon et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genes associated with common variable immunodeficiency: one diagnosis to rule them all?

Delfien BogaertMelissa DullaersBart LambrechtKarim VermaelenElfride De BaereFilomeen Haerynck

A1 Journal Article in JOURNAL OF MEDICAL GENETICS

Inflammasomes in inflammatory disease

Hanne Van GorpPedro Henrique Viana SaavedraNathalia Moraes de VasconcelosNina Van OpdenboschLieselotte Vande WalleMagdalena MatusiakFilip Van HauwermeirenG. PrencipeDelfien BogaertMelissa Dullaers et al.

JAK2 deficiency as a novel cause of impaired Th17 immunity

Filomeen HaerynckDelfien BogaertElfride De BaereKristof Van SchilFrauke CoppietersMarieke De BruyneMargot HagendorensTessa KerreFrans De BaetsMaria Bordon Cueto De Braem et al.

The immunophenotypical landscape of patients with primary antibody deficiencies and their asymptomatic first-degree relatives : arguments for a multifactorial aetiology

Delfien BogaertPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéMaria Bordon Cueto De BraemTessa KerreBart LambrechtAndrea CeruttiKarim Vermaelen et al.

Using a bronchial airway gene expression classifier

Karim VermaelenGuy Brusselle

VOC analysis in headspace air of mesothelioma and lung cancer cell lines: a comparative literature study

Sabrina LagniauKevin LamoteKarim VermaelenJan Van Meerbeeck

2015

A novel STAT1 mutation in a patient with pneumocystis jiroveci and chronic mucocutaneous candidiasis

Delfien BogaertMelissa DullaersJens StaalSarah GerloElien VandermarliereVeronique De BackerMaria Bordon Cueto De BraemKATHLEEN DE WAELEIsabelle MeytsLeen Moens et al.

Non-coding RNAs and respiratory disease

Pieter MestdaghJo VandesompeleGuy BrusselleKarim Vermaelen

A1 Journal Article in THORAX

Rehabilitation in patients with radically treated respiratory cancer : a randomised controlled trial comparing two training modalities

Bihiyga SalhiChristel HaenebalckeSilvia Perez-BogerdMai D NguyenVincent NinaneThomas MalfaitKarim VermaelenVeerle SurmontGEORGES VAN MAELERoos Colman et al.

A1 Journal Article in LUNG CANCER

The potential of radiotherapy to enhance the efficacy of renal cell carcinoma therapy

Katrien De WolfKarim VermaelenGert De MeerleerBart LambrechtPiet Ost

A1 Journal Article in ONCOIMMUNOLOGY

Unresectable stage III non-small-cell lung cancer : have we made any progress?

CAROLIEN DE TOLLENAEREYolande LievensKatrien VandecasteeleKarim VermaelenVeerle Surmont

A2 Journal Article in WORLD JOURNAL OF RESPIROLOGY

2014

A case of dendritic cell, monocyte, B and NK lymphoid deficiency (DCML)

Melissa DullaersTessa KerreFrauke CoppietersDorine SichienNancy De CabooterVeronique DebackerReinhart SpeeckaertPaul CouckeElias DebaereFilomeen Haerynck et al.

A case of isolated cerebral nocardiosis caused by a defect in the IL12-IFNG axis

Delfien BogaertVeronique DebackerSteven CallensDirk OmmeslaghMelissa DullaersKarim Vermaelen

A novel Stat1 mutation leading to hyperphosphorylation in a patient with Pneumocystis jjiroveci and chronic mucocutaneous candidiasis

Melissa DullaersJens StaalSarah GerloElien VandermarliereV DebackerMaria Bordon Cueto De BraemK De WaeleI MeytsL MoensX Bossuyt et al.

Clinical presentation of hyper-IgE syndrome in a family with impaired IL-22 production and STAT3 phosphorylation

Filomeen HaerynckDelfien BogaertElfride De BaereBart LambrechtKarim VermaelenVeronique DebackerKristof Van SchilFrans De BaetsPetra SchelstraeteMaria Bordon Cueto De Braem et al.

Lung tumours reprogram pulmonary dendritic cell immunogenicity at the microRNA level

Lotte PyfferoenPieter MestdaghKarl VergoteNancy De CabooterJo VandesompeleBart LambrechtKarim Vermaelen

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Jan Van DeunPieter MestdaghRaija SormunenVeronique CocquytKarim VermaelenJo VandesompeleMarc BrackeOlivier De WeverAn Hendrix

A2 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Jan Van DeunPieter MestdaghRaija SormunenLotte PyfferoenKarim VermaelenVeronique CocquytJo VandesompeleMarc BrackeOlivier De WeverAn Hendrix

Use of an integrative classification system and next-generation sequencing strategies for gene identification in common variable immunodeficiency disorder (CVID)

Delfien BogaertMelissa DullaersFilomeen HaerynckElfride De BaereKarim Vermaelen

2013

Contribution of four common pulmonary function tests to diagnosis of patients with respiratory symptoms : a prospective cohort study

Marc DecramerWim JanssensEric DeromGuy JoosVincent NinaneRené DemanDirk Van RenterghemGiuseppe LiistroKris Bogaertsthe Belgian Pulmonary Study Investigators et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Een 26-jarige vrouw met kortademigheid en nekpijn na een vliegtuigreis

B VantommeM Van De WalleL Van HuffelKarim VermaelenEric Derom

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Exposing a deadly alliance: novel insights into the biological links between COPD and lung cancer

Karim VermaelenGuy Brusselle

A1 Journal Article in PULMONARY PHARMACOLOGY & THERAPEUTICS

Outcome and prognostic factors of bronchopulmonary neuroendocrine tumors (BNETS): a single institutional series

Charlotte VerrokenBIRGITTA HIDDINGALiesbeth FerdinandeVeerle SurmontFrederic De RyckKarim VermaelenKaren GeboesJan Van Meerbeeck

Resistance training in patients with radically treated respiratory cancer: a prospective randomized multi-center study (REINFORCE)

Jan Van MeerbeeckBihiyga SalhiC HaenebalckeS Perez-BogerdMD NguyenThomas MalfaitKarim VermaelenVeerle SurmontGEORGES VAN MAELEEric Derom

Resistance training in patients with radically treated respiratory cancer: mature results of a multi-centre randomised phase 3 trial (REINFORCE)

Jan Van MeerbeeckBihiyga SalhiChristel HaenebalckeSylvia Perez-BogerdMay D NguyenThomas MalfaitKarim VermaelenVeerle SurmontGEORGES VAN MAELERoos Colman et al.

Second opinion for thoracic cancer and its impact on diagnosis and treatment strategy: a single institutional series

Thomas MalfaitVeerle SurmontBirgitta I HiddingaKarim VermaelenJan Van Meerbeeck

2012

Activating EGFR mutations in patients with non small cell lung cancer: prevalence and predictors in a caucasian series

Thomas MalfaitLiesbeth FerdinandeKurt TournoyD GaldermansMarleen PraetVeerle SurmontRamses ForsythKarim VermaelenJan Van Meerbeeck

Effect of radical treatment on exercise capacity and muscle force in patients with intrathoracic cancer

Bihiyga SalhiCharlotte HaenebalckeS Perez-BogerdM NguyenKarim VermaelenVeerle SurmontJan Van MeerbeeckEric Derom

Expressed wishes and incidence of euthanasia in advanced lung cancer patients

Koen PardonReginald DeschepperRobert Vander SticheleJan L BernheimFreddy MortierDenis SchallierPaul GermonpreDaniella GaldermansWillem Van KerckhovenLuc Deliens et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Feasibility of epidermal growth factor receptor mutation testing in cytology samples

Thomas MalfaitLiesbeth FerdinandeJan Van MeerbeeckD GaldermansVeerle SurmontRamses ForsythKarim VermaelenMarleen PraetKurt Tournoy

Indoleamine 2,3-dioxygenase, a new prognostic marker in sentinel lymph nodes of melanoma patients

Reinhart SpeeckaertKarim VermaelenNanja van GeelPhilippe AutierJo LambertMarc HaspeslaghMireille Van GeleKris ThielemansBart NeynsNathalie Roche et al.

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

SCID-like symptoms in a patient with chronic mucocutaneous candidiasis caused by STAT1 mutation

Melissa DullaersMaria Bordon Cueto De BraemK De WaeleI MeytsL MoensX BossuytKarim VermaelenBart LambrechtF De BaetsFilomeen Haerynck

2011

Immune reactions in benign and malignant melanocytic lesions: lessons for immunotherapy

Reinhart SpeeckaertNanja van GeelKarim VermaelenJo LambertMireille Van GeleMarijn SpeeckaertLieve Brochez

A1 Journal Article in PIGMENT CELL & MELANOMA RESEARCH

Investigational approaches for mesothelioma

Veerle SurmontEric RE Van ThielKarim VermaelenJan Van Meerbeeck

A2 Journal Article in FRONTIERS IN ONCOLOGY

Melanocyte-specific immune response in a patient with multiple regressing nevi and a history of melanoma

Reinhart SpeeckaertNanja van GeelRosalie M LuitenMireille Van GeleMarijn SpeeckaertJo LambertKarim VermaelenEsther PM TjinLieve Brochez

A1 Journal Article in ANTICANCER RESEARCH

2010

A new danger in the air: how pulmonary innate immunity copes with man-made airborne xenobiotics

Ellen LanckackerLander RobaysGuy JoosKarim Vermaelen

A1 Journal Article in Journal of Innate Immunity

Endurance and resistance training in radically treated respiratory cancer patients: a pilot study

Bihiyga SalhiIngel DemetsAnn SimpelaereSofie DecraeneKarim VermaelenVeerle SurmontJan Van MeerbeeckEric Derom

A2 Journal Article in REHABILITATION RESEARCH AND PRACTICE

First histopathological and immunophenotypic analysis of early dynamic events in a patient with segmental vitiligo associated with halo nevi

Nanja van GeelILSE MOLLETSofie De SchepperEsther PM TjinKarim VermaelenRachael A ClarkThomas S KupperRosalie M LuitenJo Lambert

A1 Journal Article in PIGMENT CELL & MELANOMA RESEARCH

Treatment of extensive-stage small cell lung carcinoma: current status and future prospects

Ingel DemedtsKarim VermaelenJan Van Meerbeeck

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

2009

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β-dependent adaptive immunity against tumors

Francois GhiringhelliLionel ApetohAntoine TesniereLaetitia AymericYuting MaKarim VermaelenTheocharis PanaretakisGrégoire MignotEvelyn UllrichJean-Luc Perfettini et al.

A1 Journal Article in NATURE MEDICINE

Between a cough and a wheeze: dendritic cells at the nexus of tobacco smoke-induced allergic airway sensitization

Lander RobaysTania MaesGuy JoosKarim Vermaelen

A1 Journal Article in MUCOSAL IMMUNOLOGY

CCR7 Modulates Pulmonary and Lymph Node Inflammatory Responses in Cigarette Smoke-Exposed Mice

Tine DemoorKen BrackeKarim VermaelenLisa DupontGuy JoosGuy Brusselle

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Concomittant inhalation of cigarette smoke and aerosolized protein activates airway dendritic cells and induces allergic airway inflammation in a TLR-independent way

Lander RobaysEllen LanckackerKatrien MoerlooseTania MaesKen BrackeGuy BrusselleGuy JoosKarim Vermaelen

A1 Journal Article in Journal of Immunology

Trimodality treatment of early stage Malignant Pleural Mesothelioma (MPM): a single institutional experience

Elke VandenbrouckeMarleen PraetKarim VermaelenVeerle SurmontFrederic De RyckKurt TournoyRobert GosselinWilfried De NeveFrank VermassenJan Van Meerbeeck

2007

Chemokine receptor CCR2 but not CCR5 or CCR6 mediates the increase in pulmonary dendritic cells during allergic airway inflammation.

Lander RobaysTania MaesS LEBECQUESA LIRAWA KUZIELGuy BrusselleGuy JoosKarim Vermaelen

A1 Journal Article in JOURNAL OF IMMUNOLOGY

2006

Murine TLR4 is implicated in cigarette smoke-induced pulmonary inflammation

Tania MaesKen BrackeKarim VermaelenIngel DemedtsGuy JoosRomain PauwelsGuy Brusselle

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

2005

Identification and characterization of human pulmonary dendritic cells

Ingel DemedtsGuy BrusselleKarim VermaelenRomain Pauwels

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Matrix metalloproteinases in asthma and COPD

Ingel DemedtsGuy BrusselleKen BrackeKarim VermaelenRomain Pauwels

A1 Journal Article in CURRENT OPINION IN PHARMACOLOGY

Pulmonary dendritic cells

Karim VermaelenRomain Pauwels

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

2004

Accurate and simple discrimination of mouse pulmonary dendritic cell and macrophage populations by flow cytometry: methodology and new insights

Karim VermaelenRomain Pauwels

A1 Journal Article in CYTOMETRY PART A

2003

Matrix metalloproteinase-9-mediated dendritic cell recruitment into the airways is a critical step in a mouse model of asthma

Karim VermaelenD CATALDOKurt TournoyTania MaesAn DhulstR LOUISJM FOIDARTA NOELRomain Pauwels

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Pulmonary dendritic cell trafficking in health and disease

Karim VermaelenRomain Pauwels

2002

Matrix metalloproteinase-9 deficiency impairs cellular infiltration and bronchial hyperresponsiveness during allergen-induced airway inflammation.

DD CATALDOKurt TournoyKarim VermaelenC MUNAUTJM FOIDARTR LOUISA NOELRomain Pauwels

A1 Journal Article in AMERICAN JOURNAL OF PATHOLOGY

2001

Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes.

Karim VermaelenInes Carro-MuinoBart LambrechtRomain Pauwels

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

1999

Allergen-induced changes in bone-marrow progenitor and airway dendritic cells in sensitized rats.

Bart LambrechtInes Carro-MuinoKarim VermaelenRomain Pauwels

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY