Doctoral project Filomeen Haerynck

Unravelling nucleolar dysfunction in lymphocytes: from novel mechanism to diagnosis of (severe) combined immune deficiency

FEBRIS: Flemish joint Effort for Biomarker pRofiling in Inflammatory Systemic diseases

Decoding GTF3A deficiency as a novel inborn error of immunity - expanding the horizons of severe combined immune deficiencies

Doctoral project Lisa Roels

Exploring the Immune Horizon: Systemic Inflammatory Diseases in the Era of SARS-CoV-2 and Beyond

From DNA damage to immune dysfunction: How defect in cell cycle regulation and DNA repair shape inborn errors of immunity

Innate immune sensors balance infection surveillance and autoinflammation

Insights into radiosensitivity and defective DNA repair in immunodeficiency syndromes

Doctoral project Lynn Backers

Expanding diagnostics in primary immunodeficiency Integrating innovations in clinical laboratory practice

A MESO QuickPlex SQ system to measure single or multiple immunotargets in biofluids

BOF-TT-professorship in paediatrics

CONDITIONAL: COvid-19: iNterplay between genetic preDisposITION and immunologicAl Landscape

‘Immunodeficiency-causing IKAROS mutations in the bright sunlight’, A comprehensive study characterizing the genetic and immunological heterogeneity in IKAROS-mediated immune diseases.

In the moonlight of GTF3A: a new way to see innate antiviral signaling?

RAPIDGEN: Rapid Assessment Platform for Severe Combined Immune Deficiency (SCID) GENe validation

TFIIIA deficiency: a novel player in severe combined immune deficiency

Unraveling the role of novel variants/genes in primary antibody deficiencies and Th17 disorders: from bed to bench and back again

A versatile microscope for the imaging of living and fixed biological samples

Description and Comparison of Biological Vulnerability in Pre- Versus Full-TermNeonates in Urban Burkina Faso (DenBalo)

From bed to bench: Insights from novel pathogenic RC3H1 and ZC3H12A variants in patients with autoimmune disease and immune dysregulation syndromes.

FullPicture: Combining Spectral Flow Cytometry with High-Speed Cell Imaging to enable comprehensive profiling of plant and animal cells and their components in real time.

Harnessing transcriptome and proteome wide analyses and engineered reporter assays to unravel the immunopathogenesis of 'multisystem inflammatory syndrome in children' (MIS-C).

The BD FACS Symphony FACS cell sorter: the most advanced multiparameter fluorescence activated cell sorter that allows the identification and purification of rare cells for further functional characterization

The DNA methylome in Common Variable Immunodeficiencies (CVID): a comprehensive study characterizing its heterogeneity and its role in disease subclassification

The role of the C3H1 zinc finger protein Roquin1 in inflammation, from a genetic survey in hyperinflammatory disorders to therapeutic applicability.

BOF-TT-professorship in paediatrics

Growth failure in pediatric CKD: a search for new therapeutic targets to mitigate inflammation driven by protein-bound uremic toxins accumulation

Investigating the effects of regulatory phosphorylation and linear ubiquitination on Pyrin-mediated auto-inflammatory disorders.