An integrated translational platform to improve the management and outcome of rare heritable connective tissue disease

Cofunding core facility - Core Zebrafish Facility Ghent (Core ZFG)

Genetic analysis in consanguineous families from Palestine : a focus on Cystic Fibrosis and Osteogenesis Imperfecta

Identification of modifier genes responsible for the phenotypic variability in Osteogenesis Imperfecta (OI)- patients using zebrafish models

Identification of modifier genes underlying the phenotypic variability in the ‘Brittle Bone Disease’, using zebrafish models and patient-derived induced pluripotent stem cells

Identification of molecular mechanisms involved in Osteogenesis Imperfecta

Study of the role of GLUT10 in cellular metabolism and growth factor signaling underlying developmental defects.

Unraveling the molecular basis of congenital heart defects

Zebrafish platform for testing pathogenicity of human disease-associated variants

Audiological en genetic determination of hearing loss in patients with Osteogenesis Imperfecta

Comparison of editing, complementing or replacement of defective RNA molecules as a novel treatment method to overcome early embryonic developmental arrest

Localization, identification and functional characterization of disease genes for retinal dystrophies.

Nuclear Transfer for female-related infertility and mitochondrial diseases

Personalized functional genomics in Mendelian diseases: from DNA variants to clinical and bioethical implications

Research equipment for behavior analysis in zebrafish disease models.

Study on the envolvement of LEMD3 and neighbouring genes on 12q14 in the pathogenesis of conditions with elevated bone density and growth disordes

Super-zoom 4D-confocal microscope for in vivo imaging

Unravelling the mitochondrial DNA reversion phenomenon