Code
01CD01324
Duration
01 October 2024 → 31 March 2025
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
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Natural sciences
- Animal cell and molecular biology
- Vertebrate biology
- Genetics
-
Medical and health sciences
- Genetics
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Engineering and technology
- Molecular and cellular biomechanics
- Genetically modified animals
Keywords
proteomics
rare disease
crispant screening
swimtunnel
Zebrafish (Danio rerio)
Osteogenesis Imperfecta (OI)
Project description
Osteogenesis Imperfecta is a skeletal disorder characterized by significant clinical variability. To gain more insights into the mechanisms responsible for this variability, various zebrafish models of OI are used for phenotypic, molecular and behavior research. These findings may contribute to potential therapies for the different forms of OI.