The role of upstream open reading frames (uORFs) in retinal health, disease and therapy

Antisense oligonucleotide therapy for genetic heterogeneous rare disorders

Design of a novel antisense oligonucleotide therapy for inherited blindness

Design of a novel antisense oligonucleotide therapy for inherited blindness

Design of a novel antisense oligonucleotide therapy for inherited blindness

Design of a novel antisense oligonucleotide therapy for inherited retinal diseases - Year 3

Evaluation of non-coding elements as novel therapeutic targets

Foundation Fighting Blindness - Toekenning: 'Long non-coding RNAs (lncRNAs) as molecular drivers and therapeutics targets of inherited retinal disease'

Functional study of a novel, long non-coding RNA (lncRNA) upstream of ABCA4 in retina and blindness

Sequencing Expertise Centre (Life Sciences)

The quest for a generic therapy for inherited blindness: NRF2 upstream open reading frames as a novel therapeutic target

Cis-regulatorische mapping van de RPE-geexpresseerde transcriptie factor OTX2

Exploring the role of non-coding variation in inherited retinal dystrophies: NMNAT1 regulatory mutations as a proof of concept

Incucyte S3: Comprehensive cellular phenotyping using high-throughput live cell imaging

ThirdGenT: linking third-generation sequencing of (epi)genomes, (epi)transcriptomes and translatomes to life sciences revolutionizes oncology, rare diseases, microbiology, cell and gene technology, developmental and computational biology

Identification of new genes and disease modifier alleles for complex retinal dystrophies and ciliopathies

In vivo study of the function of RCBTB1, a novel disease gene for inherited retinal dystrophy

Retinitis pigmentosa: gene discovery and functional analysis through advanced genomics and zebrafish studies

Precision medicine in inherited blindness using integrated omics in human and animal models